Saquinavir_NCI-H596 Gene Set
Genes
51 genes differentially expressed following the Saquinavir_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AKAP12
|
A kinase (PRKA) anchor protein 12
|
0.224281
|
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1
|
0.197725
|
|
EFNA5
|
ephrin-A5
|
0.193193
|
|
MYO1E
|
myosin IE
|
0.188621
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
0.140902
|
|
PKM
|
pyruvate kinase, muscle
|
0.140182
|
|
ANXA2
|
annexin A2
|
0.124306
|
|
DSCAM
|
Down syndrome cell adhesion molecule
|
0.121847
|
|
NDRG1
|
N-myc downstream regulated 1
|
0.119056
|
|
CD55
|
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
|
0.108569
|
|
B2M
|
beta-2-microglobulin
|
0.106104
|
|
VIM
|
vimentin
|
0.105998
|
|
AHNAK
|
AHNAK nucleoprotein
|
0.0996529
|
|
AKAP13
|
A kinase (PRKA) anchor protein 13
|
0.0934019
|
|
GOLGA4
|
golgin A4
|
0.0921769
|
|
HSPA5
|
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
|
0.0837561
|
|
TPT1
|
tumor protein, translationally-controlled 1
|
0.0666003
|
|
TRIO
|
trio Rho guanine nucleotide exchange factor
|
0.0526169
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
0.0525495
|
|
CDC42BPA
|
CDC42 binding protein kinase alpha (DMPK-like)
|
0.0478863
|
|
ASPH
|
aspartate beta-hydroxylase
|
0.0395643
|
|
RPS6
|
ribosomal protein S6
|
0.0358571
|
|
MMAB
|
methylmalonic aciduria (cobalamin deficiency) cblB type
|
0.0357569
|
|
MT2A
|
metallothionein 2A
|
0.03274
|
|
FN1
|
fibronectin 1
|
0.026883
|
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
0.0200953
|
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific
|
0.0119924
|
|
NALF1
|
NALCN channel auxiliary factor 1
|
0.00701386
|
|
LAMA4
|
laminin, alpha 4
|
8.94985E-4
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PTMA
|
prothymosin, alpha
|
-0.2089
|
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase
|
-0.178071
|
|
JMJD1C
|
jumonji domain containing 1C
|
-0.173665
|
|
RPS16
|
ribosomal protein S16
|
-0.15786
|
|
SNX9
|
sorting nexin 9
|
-0.15558
|
|
LMO7
|
LIM domain 7
|
-0.143866
|
|
COL6A3
|
collagen, type VI, alpha 3
|
-0.129476
|
|
NAV2
|
neuron navigator 2
|
-0.114417
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-0.0870289
|
|
PSD3
|
pleckstrin and Sec7 domain containing 3
|
-0.078214
|
|
LIMS1
|
LIM and senescent cell antigen-like domains 1
|
-0.0700326
|
|
DPP10
|
dipeptidyl-peptidase 10 (non-functional)
|
-0.058462
|
|
NKD1
|
naked cuticle homolog 1 (Drosophila)
|
-0.0540324
|
|
FNDC3B
|
fibronectin type III domain containing 3B
|
-0.0475184
|
|
PDE3A
|
phosphodiesterase 3A, cGMP-inhibited
|
-0.0469548
|
|
INHBA
|
inhibin, beta A
|
-0.0467284
|
|
TMSB10
|
thymosin beta 10
|
-0.0363298
|
|
MAML3
|
mastermind-like 3 (Drosophila)
|
-0.0350195
|
|
ROBO2
|
roundabout, axon guidance receptor, homolog 2 (Drosophila)
|
-0.0270554
|
|
PITPNC1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
-0.0248559
|
|
TXNRD1
|
thioredoxin reductase 1
|
-0.0247015
|
|
RPS8
|
ribosomal protein S8
|
-0.0126006
|
