| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.0759697 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0733704 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0707737 |
| JMJD1C | jumonji domain containing 1C | 0.0695754 |
| SPAG9 | sperm associated antigen 9 | 0.0692375 |
| DST | dystonin | 0.0657452 |
| RASAL2 | RAS protein activator like 2 | 0.0603999 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0603505 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0557512 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0530034 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0527589 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0524877 |
| RPS6 | ribosomal protein S6 | 0.0519936 |
| PRTG | protogenin | 0.0512823 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0478158 |
| RPS12 | ribosomal protein S12 | 0.0475063 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.046971 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0468426 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0460991 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.04482 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.044363 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0442548 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0433842 |
| ATXN2 | ataxin 2 | 0.0432425 |
| FBXO11 | F-box protein 11 | 0.0432041 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0430504 |
| RPS8 | ribosomal protein S8 | 0.0427064 |
| USP25 | ubiquitin specific peptidase 25 | 0.0424598 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.040722 |
| GOLGB1 | golgin B1 | 0.0399598 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.03856 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0375741 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0368857 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0365367 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0362822 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0361135 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0350534 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0350279 |
| MB21D2 | Mab-21 domain containing 2 | 0.0344323 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0341294 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0341032 |
| EFNA5 | ephrin-A5 | 0.0339511 |
| WWC2 | WW and C2 domain containing 2 | 0.0339403 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0339221 |
| SRPK2 | SRSF protein kinase 2 | 0.0332851 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0326231 |
| B2M | beta-2-microglobulin | 0.0320806 |
| RPS3 | ribosomal protein S3 | 0.0320671 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0320201 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0319408 |
| PHIP | pleckstrin homology domain interacting protein | 0.0319075 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0317533 |
| CEP350 | centrosomal protein 350kDa | 0.0314983 |
| NBEAL1 | neurobeachin-like 1 | 0.0314032 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0313577 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0313079 |
| VCL | vinculin | 0.0311202 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0310233 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0309594 |
| RPS16 | ribosomal protein S16 | 0.0308942 |
| CCDC88A | coiled-coil domain containing 88A | 0.0307677 |
| RPL35A | ribosomal protein L35a | 0.0306303 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0305011 |
| RBM20 | RNA binding motif protein 20 | 0.030379 |
| COG5 | component of oligomeric golgi complex 5 | 0.0301954 |
| FGF13 | fibroblast growth factor 13 | 0.0298843 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0298705 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0298446 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.029231 |
| LYST | lysosomal trafficking regulator | 0.0291817 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0291813 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0291576 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0291506 |
| RIGI | RNA sensor RIG-I | 0.0290984 |
| CTBP2 | C-terminal binding protein 2 | 0.0290316 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0289966 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.028936 |
| ITSN2 | intersectin 2 | 0.0289177 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.028886 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0288712 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.028508 |
| INTS6 | integrator complex subunit 6 | 0.0279056 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0278352 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0278059 |
| ERBIN | erbb2 interacting protein | 0.0276476 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0275132 |
| HIP1 | huntingtin interacting protein 1 | 0.0274765 |
| RPLP0 | ribosomal protein, large, P0 | 0.0274615 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0268229 |
| FMNL2 | formin-like 2 | 0.0267722 |
| SMYD3 | SET and MYND domain containing 3 | 0.0266671 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0266255 |
| PTEN | phosphatase and tensin homolog | 0.0263379 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260749 |
| GPHN | gephyrin | 0.0258862 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0255985 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0255621 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.025473 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0254523 |
| RPL23 | ribosomal protein L23 | 0.0254111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.13744 |
| COL11A1 | collagen, type XI, alpha 1 | -0.125563 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.122367 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.117027 |
| GPC3 | glypican 3 | -0.109994 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.102539 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0914356 |
| ITGAV | integrin, alpha V | -0.0886832 |
| NRG1 | neuregulin 1 | -0.0884822 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0872629 |
| PCDH9 | protocadherin 9 | -0.086993 |
| THBS1 | thrombospondin 1 | -0.0834686 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0812484 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0800108 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0759731 |
| PTMA | prothymosin, alpha | -0.0728664 |
| EMP1 | epithelial membrane protein 1 | -0.0647031 |
| METAP2 | methionyl aminopeptidase 2 | -0.0638444 |
| TMSB10 | thymosin beta 10 | -0.0610756 |
| COL5A2 | collagen, type V, alpha 2 | -0.0599911 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0599816 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.059052 |
| AHNAK | AHNAK nucleoprotein | -0.0580378 |
| MKI67 | marker of proliferation Ki-67 | -0.0568768 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0563681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0554212 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0538005 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0536273 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.053323 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0528964 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0519739 |
| POTEF | POTE ankyrin domain family, member F | -0.0487925 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0479387 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0453329 |
| LRRC4C | leucine rich repeat containing 4C | -0.0450809 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0443687 |
| MAP4 | microtubule-associated protein 4 | -0.042528 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.042068 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0405217 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0401579 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0400196 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0399172 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0390327 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0385126 |
| CALR | calreticulin | -0.0381661 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0381522 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0376081 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0375741 |
| ACTN4 | actinin, alpha 4 | -0.0373209 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.036593 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0360617 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0359983 |
| TMSB4X | thymosin beta 4, X-linked | -0.0358943 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0353945 |
| ACTG1 | actin gamma 1 | -0.0353112 |
| COL1A2 | collagen, type I, alpha 2 | -0.0334353 |
| SET | SET nuclear proto-oncogene | -0.0332294 |
| HMCN1 | hemicentin 1 | -0.0329654 |
| TPX2 | TPX2, microtubule-associated | -0.0327492 |
| UBC | ubiquitin C | -0.0327339 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0323584 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0320395 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0311435 |
| CCDC102B | coiled-coil domain containing 102B | -0.0308897 |
| TUBB | tubulin, beta class I | -0.0301229 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0299276 |
| NONO | non-POU domain containing, octamer-binding | -0.0299217 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0297868 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0293704 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0291794 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0291517 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0285434 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0284967 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0284635 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0284278 |
| THOC2 | THO complex 2 | -0.02839 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0283239 |
| HMGB2 | high mobility group box 2 | -0.0283125 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0280152 |
| PFN1 | profilin 1 | -0.0278751 |
| KHSRP | KH-type splicing regulatory protein | -0.0277686 |
| TEX11 | testis expressed 11 | -0.0277029 |
| CBX5 | chromobox homolog 5 | -0.0276658 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | -0.02748 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0274762 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0273379 |
| EPHA3 | EPH receptor A3 | -0.0270432 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.026979 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0268336 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265555 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0263738 |
| CAVIN1 | caveolae associated protein 1 | -0.0262412 |
| VIM | vimentin | -0.0259784 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0259711 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0258457 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0258096 |
| ENO1 | enolase 1, (alpha) | -0.0256062 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0255643 |
| CANX | calnexin | -0.0253496 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0252678 |
