| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.165419 |
| ZNF292 | zinc finger protein 292 | 0.0784531 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0765682 |
| ECT2 | epithelial cell transforming 2 | 0.0694461 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0685108 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0652833 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.064394 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0641538 |
| MT2A | metallothionein 2A | 0.0576062 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0564431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0553252 |
| CDC73 | cell division cycle 73 | 0.0552947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0541852 |
| RNF145 | ring finger protein 145 | 0.0531739 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.051219 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0498488 |
| NAV2 | neuron navigator 2 | 0.049795 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0485194 |
| QKI | QKI, KH domain containing, RNA binding | 0.0481567 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0473728 |
| ANLN | anillin, actin binding protein | 0.0471748 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0465352 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0455017 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0447309 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0439305 |
| DUSP6 | dual specificity phosphatase 6 | 0.0438224 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0429667 |
| RLF | rearranged L-myc fusion | 0.0425212 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0422891 |
| RBM25 | RNA binding motif protein 25 | 0.0419001 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0417336 |
| DIAPH3 | diaphanous-related formin 3 | 0.0414982 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0408169 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0403052 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0400863 |
| RRM2 | ribonucleotide reductase M2 | 0.0383246 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0380002 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.037466 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0369075 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0368543 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0367811 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0363601 |
| JMJD1C | jumonji domain containing 1C | 0.0363471 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0354514 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0354311 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0350923 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0342541 |
| EZR | ezrin | 0.0341878 |
| PUM1 | pumilio RNA-binding family member 1 | 0.03303 |
| STK4 | serine/threonine kinase 4 | 0.0325623 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0323704 |
| MORF4L2 | mortality factor 4 like 2 | 0.0320899 |
| ERBIN | erbb2 interacting protein | 0.0320511 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0316252 |
| S100A6 | S100 calcium binding protein A6 | 0.0315823 |
| H3-3B | H3.3 histone B | 0.0315748 |
| RAD21 | RAD21 homolog (S. pombe) | 0.031432 |
| RTN4 | reticulon 4 | 0.0313191 |
| RPS3 | ribosomal protein S3 | 0.0311143 |
| CKAP2 | cytoskeleton associated protein 2 | 0.030714 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0303708 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0303443 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0303382 |
| TMSB4X | thymosin beta 4, X-linked | 0.0300509 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.029673 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0296538 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.02946 |
| CCNI | cyclin I | 0.0293121 |
| CRY1 | cryptochrome circadian clock 1 | 0.0286905 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0285556 |
| ANXA1 | annexin A1 | 0.0285333 |
| PARD3 | par-3 family cell polarity regulator | 0.0285331 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0283655 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0282664 |
| TPX2 | TPX2, microtubule-associated | 0.028153 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0281244 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0281038 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0276666 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0274289 |
| NUP58 | nucleoporin 58 | 0.0273069 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.027098 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0270224 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0267972 |
| CENPF | centromere protein F, 350/400kDa | 0.0267333 |
| KIF18B | kinesin family member 18B | 0.0265255 |
| ADD1 | adducin 1 (alpha) | 0.0263163 |
| USP3 | ubiquitin specific peptidase 3 | 0.0262636 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0260312 |
| CTBP2 | C-terminal binding protein 2 | 0.0259524 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0259445 |
| PHIP | pleckstrin homology domain interacting protein | 0.0257523 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0257233 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0255852 |
| TTK | TTK protein kinase | 0.025391 |
| ATOSA | atos homolog A | 0.0253637 |
| RPS24 | ribosomal protein S24 | 0.0252335 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | 0.0251956 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.0251035 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0249684 |
| RHEB | Ras homolog enriched in brain | 0.02493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.104177 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0905949 |
| RPL35A | ribosomal protein L35a | -0.0797819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0791346 |
| PKM | pyruvate kinase, muscle | -0.0775652 |
| RPS6 | ribosomal protein S6 | -0.0770856 |
| FHIT | fragile histidine triad | -0.0725099 |
| EGFR | epidermal growth factor receptor | -0.0719477 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0713619 |
| RPL31 | ribosomal protein L31 | -0.0701369 |
| TJP1 | tight junction protein 1 | -0.0681795 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0613883 |
| AHNAK | AHNAK nucleoprotein | -0.0592503 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0591657 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0580761 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0572043 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0567228 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0546901 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0539998 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0532982 |
| POTEF | POTE ankyrin domain family, member F | -0.0520085 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.051636 |
| GLI2 | GLI family zinc finger 2 | -0.0513724 |
| EFNA5 | ephrin-A5 | -0.0505812 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0492281 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0491187 |
| PYGB | phosphorylase, glycogen; brain | -0.0478697 |
| RPL3 | ribosomal protein L3 | -0.0473273 |
| GOLGA4 | golgin A4 | -0.0471752 |
| RPL37A | ribosomal protein L37a | -0.0438998 |
| NBEA | neurobeachin | -0.0432689 |
| TXNRD1 | thioredoxin reductase 1 | -0.0428031 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0413569 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0403438 |
| ENO1 | enolase 1, (alpha) | -0.0398482 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0394433 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0387217 |
| ONECUT2 | one cut homeobox 2 | -0.03825 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0374878 |
| FLNB | filamin B, beta | -0.0368262 |
| SQSTM1 | sequestosome 1 | -0.0366959 |
| YEATS2 | YEATS domain containing 2 | -0.0359286 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0359013 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0353788 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0353605 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0351181 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0351032 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0345861 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0345653 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0343618 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0343211 |
| RPL36 | ribosomal protein L36 | -0.0342638 |
| RPLP2 | ribosomal protein, large, P2 | -0.0339855 |
| RPS27 | ribosomal protein S27 | -0.0336797 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0336021 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0335357 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0322332 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0320241 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0311505 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0308818 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0302578 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.029914 |
| HM13 | histocompatibility (minor) 13 | -0.0297956 |
| RPL9 | ribosomal protein L9 | -0.0296271 |
| CLIC4 | chloride intracellular channel 4 | -0.0295908 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0295653 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0295529 |
| CD47 | CD47 molecule | -0.0290227 |
| GPHN | gephyrin | -0.0288572 |
| BMP2K | BMP2 inducible kinase | -0.0288155 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0286449 |
| EMP3 | epithelial membrane protein 3 | -0.0285387 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0282857 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0280673 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0273963 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0270974 |
| RPS23 | ribosomal protein S23 | -0.0270324 |
| TMEM165 | transmembrane protein 165 | -0.0270238 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0269872 |
| PDE10A | phosphodiesterase 10A | -0.0267989 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0267179 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0265461 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0264787 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.0261996 |
| USP25 | ubiquitin specific peptidase 25 | -0.0260485 |
| TULP4 | tubby like protein 4 | -0.0252728 |
| RPL21 | ribosomal protein L21 | -0.0251233 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0250166 |
| CUL5 | cullin 5 | -0.0246997 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0244374 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0244364 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.024326 |
| TMSB10 | thymosin beta 10 | -0.0241305 |
| RFX7 | regulatory factor X, 7 | -0.0240838 |
| ITGAV | integrin, alpha V | -0.0237137 |
| ATN1 | atrophin 1 | -0.0234836 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0234534 |
| RPS19 | ribosomal protein S19 | -0.0233289 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0230969 |
| QSER1 | glutamine and serine rich 1 | -0.0229873 |
