| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.243392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0762582 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0746954 |
| IER3 | immediate early response 3 | 0.0700148 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0687844 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.06794 |
| HDAC9 | histone deacetylase 9 | 0.0656642 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0640743 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0622628 |
| SQSTM1 | sequestosome 1 | 0.0585805 |
| LDHA | lactate dehydrogenase A | 0.0542248 |
| SPAG9 | sperm associated antigen 9 | 0.0500095 |
| CADM1 | cell adhesion molecule 1 | 0.0495856 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.04391 |
| INTS6 | integrator complex subunit 6 | 0.0409823 |
| RPLP0 | ribosomal protein, large, P0 | 0.0399607 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0397796 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.039051 |
| ADM | adrenomedullin | 0.0377181 |
| MYOF | myoferlin | 0.0369745 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0358122 |
| PRELID2 | PRELI domain containing 2 | 0.0350372 |
| ARFGEF3 | ARFGEF family member 3 | 0.0350169 |
| RPS3 | ribosomal protein S3 | 0.0330723 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0313332 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0307593 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0301034 |
| PGK1 | phosphoglycerate kinase 1 | 0.0298198 |
| RND3 | Rho family GTPase 3 | 0.0285039 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0284108 |
| UBC | ubiquitin C | 0.0284034 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0280752 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0278785 |
| OGA | O-GlcNAcase | 0.0278707 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0275928 |
| RYBP | RING1 and YY1 binding protein | 0.0275901 |
| NAV2 | neuron navigator 2 | 0.0263529 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0258675 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0252007 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0249462 |
| SDCBP | syndecan binding protein (syntenin) | 0.024922 |
| CD164 | CD164 molecule, sialomucin | 0.0248568 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0245501 |
| RPS12 | ribosomal protein S12 | 0.02396 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0236269 |
| RPL7 | ribosomal protein L7 | 0.0234386 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0229627 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0224786 |
| HELZ | helicase with zinc finger | 0.0223959 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0219522 |
| CD109 | CD109 molecule | 0.0218161 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0217916 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0213429 |
| MORF4L2 | mortality factor 4 like 2 | 0.0211667 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0211386 |
| STAG2 | stromal antigen 2 | 0.0211166 |
| RPS4X | ribosomal protein S4, X-linked | 0.0211117 |
| ZNF292 | zinc finger protein 292 | 0.0201253 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0198446 |
| SEC24A | SEC24 family member A | 0.0198391 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0197417 |
| RPS24 | ribosomal protein S24 | 0.0196618 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.019657 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0194205 |
| PHIP | pleckstrin homology domain interacting protein | 0.0189443 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0189135 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.01843 |
| DTNA | dystrobrevin, alpha | 0.0183956 |
| CALR | calreticulin | 0.0181432 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0179644 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0179516 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0179338 |
| TRAM2 | translocation associated membrane protein 2 | 0.0176268 |
| TMEM132D | transmembrane protein 132D | 0.0173741 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.01731 |
| IRS2 | insulin receptor substrate 2 | 0.0169857 |
| RLF | rearranged L-myc fusion | 0.0169705 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0169099 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0168786 |
| CERT1 | ceramide transporter 1 | 0.0168676 |
| JAK1 | Janus kinase 1 | 0.0168107 |
| SMYD3 | SET and MYND domain containing 3 | 0.0167259 |
| PCBP3 | poly(rC) binding protein 3 | 0.0167228 |
| SP100 | SP100 nuclear antigen | 0.0166865 |
| QKI | QKI, KH domain containing, RNA binding | 0.0166391 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0165898 |
| RPL37 | ribosomal protein L37 | 0.0165037 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0164203 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0163433 |
| USP12 | ubiquitin specific peptidase 12 | 0.0163237 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0162495 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0162302 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0161818 |
| B2M | beta-2-microglobulin | 0.0160597 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0157279 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0156808 |
| WTAP | Wilms tumor 1 associated protein | 0.0155606 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.015557 |
| CALU | calumenin | 0.0154828 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0152879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.192735 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.158242 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.148064 |
| VEGFA | vascular endothelial growth factor A | -0.0976096 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0973861 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0954752 |
| VIM | vimentin | -0.0902306 |
| TMSB10 | thymosin beta 10 | -0.0852778 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0772792 |
| TPM4 | tropomyosin 4 | -0.0739833 |
| GLIS3 | GLIS family zinc finger 3 | -0.0678991 |
| VCL | vinculin | -0.0666485 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0663558 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0661041 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0632982 |
| FRMD4A | FERM domain containing 4A | -0.0608896 |
| CD44 | CD44 molecule (Indian blood group) | -0.0593432 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0592602 |
| RAI14 | retinoic acid induced 14 | -0.0578776 |
| RTN4 | reticulon 4 | -0.0578231 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0553501 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0547832 |
| VCAN | versican | -0.0536854 |
| MSN | moesin | -0.0535489 |
| RPS6 | ribosomal protein S6 | -0.0517328 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0502644 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0466917 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0456254 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0445713 |
| AHNAK | AHNAK nucleoprotein | -0.0441765 |
| HLA-B | major histocompatibility complex, class I, B | -0.0440766 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0437652 |
| VMP1 | vacuole membrane protein 1 | -0.0406421 |
| EGR1 | early growth response 1 | -0.0401544 |
| PTMA | prothymosin, alpha | -0.0399137 |
| KRT19 | keratin 19, type I | -0.0393636 |
| RPLP2 | ribosomal protein, large, P2 | -0.0378701 |
| CLMP | CXADR-like membrane protein | -0.0376558 |
| THBS1 | thrombospondin 1 | -0.0373301 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0371194 |
| C3 | complement component 3 | -0.0364993 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0350542 |
| NRP1 | neuropilin 1 | -0.034865 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0344574 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0335488 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0328745 |
| CENPF | centromere protein F, 350/400kDa | -0.0325014 |
| CDCP1 | CUB domain containing protein 1 | -0.0323782 |
| SBF2 | SET binding factor 2 | -0.0318959 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0309094 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0304188 |
| FLNB | filamin B, beta | -0.0303881 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0300212 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0299956 |
| RPL35A | ribosomal protein L35a | -0.029499 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0292068 |
| RPS19 | ribosomal protein S19 | -0.0289545 |
| PALLD | palladin, cytoskeletal associated protein | -0.0289495 |
| RPS21 | ribosomal protein S21 | -0.0287303 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0283026 |
| TPM1 | tropomyosin 1 (alpha) | -0.0283022 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0281802 |
| COL1A2 | collagen, type I, alpha 2 | -0.0281243 |
| IL6 | interleukin 6 | -0.0280037 |
| S100A9 | S100 calcium binding protein A9 | -0.0272918 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0270751 |
| TNS3 | tensin 3 | -0.0267469 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0263743 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0261966 |
| RPL23 | ribosomal protein L23 | -0.0249612 |
| MX1 | MX dynamin-like GTPase 1 | -0.0249432 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0247706 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0244381 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024294 |
| RPLP1 | ribosomal protein, large, P1 | -0.0238721 |
| NABP1 | nucleic acid binding protein 1 | -0.0236985 |
| PKM | pyruvate kinase, muscle | -0.0236627 |
| TXNRD1 | thioredoxin reductase 1 | -0.0235992 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0235922 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0232752 |
| MKI67 | marker of proliferation Ki-67 | -0.0230533 |
| RPL19 | ribosomal protein L19 | -0.0228394 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0226456 |
| MAP1B | microtubule-associated protein 1B | -0.0222263 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0221864 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0219555 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0218264 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0216968 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0215619 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0213729 |
| RNF213 | ring finger protein 213 | -0.0212086 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0211154 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0210694 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0206519 |
| RPS14 | ribosomal protein S14 | -0.0205353 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0204703 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0203787 |
| TMEM41B | transmembrane protein 41B | -0.0203007 |
| RPL36 | ribosomal protein L36 | -0.0200043 |
| CAB39 | calcium binding protein 39 | -0.0198578 |
