| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.202464 |
| CD44 | CD44 molecule (Indian blood group) | 0.0975846 |
| NRXN3 | neurexin 3 | 0.0887119 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0867333 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0843559 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0757463 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0671869 |
| HIP1 | huntingtin interacting protein 1 | 0.0631882 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0605414 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0597703 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0581838 |
| KYNU | kynureninase | 0.0548602 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0544112 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0543612 |
| VCL | vinculin | 0.0526423 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0524492 |
| RPS12 | ribosomal protein S12 | 0.0513563 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0481606 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0475599 |
| SQSTM1 | sequestosome 1 | 0.0471732 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0469858 |
| HDAC9 | histone deacetylase 9 | 0.0466382 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.045989 |
| DST | dystonin | 0.0453297 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0445021 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0407866 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0388529 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0379332 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0378239 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0376855 |
| MYO1E | myosin IE | 0.035943 |
| HMGA2 | high mobility group AT-hook 2 | 0.0354426 |
| PRELID2 | PRELI domain containing 2 | 0.0351576 |
| GLIS3 | GLIS family zinc finger 3 | 0.0351334 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0347896 |
| FHIT | fragile histidine triad | 0.0344352 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0342909 |
| RAD51B | RAD51 paralog B | 0.0342367 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0336962 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0335693 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0334281 |
| MORF4L2 | mortality factor 4 like 2 | 0.0330544 |
| RUNX1 | runt-related transcription factor 1 | 0.0329826 |
| VEGFC | vascular endothelial growth factor C | 0.0325904 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0321819 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0320922 |
| RAB7A | RAB7A, member RAS oncogene family | 0.032054 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.031574 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0315149 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0314646 |
| ATXN1 | ataxin 1 | 0.0313566 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.03124 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0312104 |
| INTS6 | integrator complex subunit 6 | 0.0311452 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0305196 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0304817 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0301445 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0296245 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0292704 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0291043 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0286015 |
| EXOC4 | exocyst complex component 4 | 0.0282825 |
| SETX | senataxin | 0.0278967 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0275879 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.027269 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0272132 |
| METTL15 | methyltransferase like 15 | 0.0270286 |
| NBEAL1 | neurobeachin-like 1 | 0.0269964 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0268691 |
| PGK1 | phosphoglycerate kinase 1 | 0.026601 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0263341 |
| COG5 | component of oligomeric golgi complex 5 | 0.0260548 |
| MED13L | mediator complex subunit 13-like | 0.0256299 |
| JPH2 | junctophilin 2 | 0.0254659 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0253411 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.025333 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0249052 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0247602 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0244314 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.024317 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0241404 |
| SCFD1 | sec1 family domain containing 1 | 0.0240748 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0240552 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0240092 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0239459 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0238059 |
| EGFR | epidermal growth factor receptor | 0.0238035 |
| GSE1 | Gse1 coiled-coil protein | 0.0237195 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0237093 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0236406 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0235821 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0235455 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0235155 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0233206 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0231566 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0231434 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0229973 |
| NDRG1 | N-myc downstream regulated 1 | 0.0228598 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0228314 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0227772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199736 |
| MT2A | metallothionein 2A | -0.103925 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0677887 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0624893 |
| ANXA5 | annexin A5 | -0.0505809 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0493476 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0481256 |
| PTMA | prothymosin, alpha | -0.0414141 |
| COL1A1 | collagen, type I, alpha 1 | -0.0408428 |
| UBC | ubiquitin C | -0.0403249 |
| HDLBP | high density lipoprotein binding protein | -0.0388077 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0378936 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0365592 |
| HMGB2 | high mobility group box 2 | -0.0363295 |
| B2M | beta-2-microglobulin | -0.0335476 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0333742 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0331006 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0306459 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0305957 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.030586 |
| TMSB10 | thymosin beta 10 | -0.0304539 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0302028 |
| TMEM41B | transmembrane protein 41B | -0.0298819 |
| HLA-C | major histocompatibility complex, class I, C | -0.0298235 |
| ENO1 | enolase 1, (alpha) | -0.029192 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0291803 |
| TPM2 | tropomyosin 2 (beta) | -0.029102 |
| FTL | ferritin, light polypeptide | -0.0289396 |
| CCNI | cyclin I | -0.0284628 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0277109 |
| SDC4 | syndecan 4 | -0.0275043 |
| MT1X | metallothionein 1X | -0.0268861 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0265701 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0263175 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0262858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0254261 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0248309 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.0248205 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0246694 |
| COL1A2 | collagen, type I, alpha 2 | -0.02437 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0243556 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0243188 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0241977 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0240138 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0240039 |
| CANX | calnexin | -0.0239501 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0234088 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0232894 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0232724 |
| POM121 | POM121 transmembrane nucleoporin | -0.0232358 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0232316 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0230041 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0229799 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.022951 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0227031 |
| FAM3C | family with sequence similarity 3, member C | -0.0224511 |
| THOC2 | THO complex 2 | -0.0222525 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0221882 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0221615 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0220603 |
| CALU | calumenin | -0.021986 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0219594 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0219368 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0217759 |
| NUCB2 | nucleobindin 2 | -0.0217185 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0216397 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0216102 |
| GCN1 | GCN1 activator of EIF2AK4 | -0.0216023 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0214705 |
| ZNF292 | zinc finger protein 292 | -0.0212313 |
| SIL1 | SIL1 nucleotide exchange factor | -0.02111 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0210986 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0208804 |
| SRP54 | signal recognition particle 54kDa | -0.0207472 |
| RPS11 | ribosomal protein S11 | -0.0206973 |
| S100A10 | S100 calcium binding protein A10 | -0.0205528 |
| RPS13 | ribosomal protein S13 | -0.0204717 |
| CABIN1 | calcineurin binding protein 1 | -0.0202741 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0200656 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0200468 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -0.0200277 |
| ZNF207 | zinc finger protein 207 | -0.0198161 |
| TMSB4X | thymosin beta 4, X-linked | -0.0198053 |
| TFG | TRK-fused gene | -0.0197692 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0196507 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0195642 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0194882 |
| FN1 | fibronectin 1 | -0.0194321 |
| CD99 | CD99 molecule | -0.0193629 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0193428 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0192659 |
| COL5A2 | collagen, type V, alpha 2 | -0.0192619 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -0.0192499 |
| ARF4 | ADP-ribosylation factor 4 | -0.0190915 |
| FOXP1 | forkhead box P1 | -0.0190134 |
| OST4 | oligosaccharyltransferase 4 homolog (S. cerevisiae) | -0.0189952 |
| ZNF326 | zinc finger protein 326 | -0.0189841 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0189587 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0189125 |
| RHEB | Ras homolog enriched in brain | -0.0187464 |
