Schistosomiasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria. (Human Disease Ontology, DOID_1395)
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Genes

555 genes co-occuring with the disease Schistosomiasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FAM53B family with sequence similarity 53, member B 3.227
IL4 interleukin 4 3.072
IL13 interleukin 13 2.97
TXNRD3 thioredoxin reductase 3 2.938
IFNG interferon, gamma 2.931
IL10 interleukin 10 2.917
IL5 interleukin 5 2.898
CD4 CD4 molecule 2.814
TGFB1 transforming growth factor, beta 1 2.619
THBS2 thrombospondin 2 2.601
TNF tumor necrosis factor 2.519
IL2 interleukin 2 2.445
IL17A interleukin 17A 2.439
IL6 interleukin 6 2.415
IL4R interleukin 4 receptor 2.389
ALB albumin 2.38
CD8A CD8a molecule 2.369
IL1B interleukin 1, beta 2.36
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.341
SNAI1 snail family zinc finger 1 2.312
CTSB cathepsin B 2.292
ARG1 arginase 1 2.27
FOXP3 forkhead box P3 2.267
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.266
TSPAN2 tetraspanin 2 2.241
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.238
IL13RA2 interleukin 13 receptor, alpha 2 2.135
IL33 interleukin 33 2.129
PSAPL1 prosaposin-like 1 (gene/pseudogene) 2.114
TLR2 toll-like receptor 2 2.112
TLR4 toll-like receptor 4 2.11
IL1A interleukin 1, alpha 2.105
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.085
IL13RA1 interleukin 13 receptor, alpha 1 2.084
TPI1 triosephosphate isomerase 1 2.073
IL9 interleukin 9 2.039
RNASE3 ribonuclease, RNase A family, 3 1.962
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.953
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.953
TXN thioredoxin 1.951
PXDN peroxidasin 1.941
PXDNL peroxidasin-like 1.93
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.93
CCL2 chemokine (C-C motif) ligand 2 1.92
CTSL cathepsin L 1.909
CD86 CD86 molecule 1.905
HSPG2 heparan sulfate proteoglycan 2 1.904
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.892
F2 coagulation factor II (thrombin) 1.891
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.887
CCL3 chemokine (C-C motif) ligand 3 1.887
HDAC8 histone deacetylase 8 1.884
HPGDS hematopoietic prostaglandin D synthase 1.882
TIMP1 TIMP metallopeptidase inhibitor 1 1.874
MAGEH1 melanoma antigen family H1 1.873
IL22 interleukin 22 1.866
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.865
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 1.864
CCL5 chemokine (C-C motif) ligand 5 1.842
HSPA4 heat shock 70kDa protein 4 1.839
CCL11 chemokine (C-C motif) ligand 11 1.833
CD40 CD40 molecule, TNF receptor superfamily member 5 1.83
CTSS cathepsin S 1.822
MYD88 myeloid differentiation primary response 88 1.818
CD80 CD80 molecule 1.812
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.806
PSAP prosaposin 1.803
FN1 fibronectin 1 1.802
MRC1 mannose receptor, C type 1 1.797
TSLP thymic stromal lymphopoietin 1.796
TP53 tumor protein p53 1.796
LGMN legumain 1.793
PTPRC protein tyrosine phosphatase, receptor type, C 1.783
SMAD7 SMAD family member 7 1.778
EPX eosinophil peroxidase 1.773
IL18 interleukin 18 1.763
TLR9 toll-like receptor 9 1.763
CXCL8 chemokine (C-X-C motif) ligand 8 1.762
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.76
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.758
CD209 CD209 molecule 1.752
GATA3 GATA binding protein 3 1.745
TLR3 toll-like receptor 3 1.741
CXCL10 chemokine (C-X-C motif) ligand 10 1.735
ARG2 arginase 2 1.731
CCL4 chemokine (C-C motif) ligand 4 1.729
KCNK3 potassium channel, two pore domain subfamily K, member 3 1.728
SMAD2 SMAD family member 2 1.727
CCN2 cellular communication network factor 2 1.718
PRDX2 peroxiredoxin 2 1.711
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.707
CD1D CD1d molecule 1.7
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.7
MMP9 matrix metallopeptidase 9 1.699
CD19 CD19 molecule 1.692
IL3 interleukin 3 1.691
SMAD3 SMAD family member 3 1.684
ERVW-1 endogenous retrovirus group W, member 1 1.683
IFNA1 interferon, alpha 1 1.682
RETNLB resistin like beta 1.681
TBX21 T-box 21 1.68
CRP C-reactive protein, pentraxin-related 1.679
GLRX glutaredoxin (thioltransferase) 1.676
ACVRL1 activin A receptor type II-like 1 1.666
CCR2 chemokine (C-C motif) receptor 2 1.657
STAT1 signal transducer and activator of transcription 1, 91kDa 1.656
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.654
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.649
AFP alpha-fetoprotein 1.647
PPARG peroxisome proliferator-activated receptor gamma 1.644
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.641
GSR glutathione reductase 1.639
IL10RA interleukin 10 receptor, alpha 1.638
ERV3-1 endogenous retrovirus group 3, member 1 1.637
APOL1 apolipoprotein L, 1 1.633
EDN1 endothelin 1 1.633
TGFBR1 transforming growth factor, beta receptor 1 1.631
C3 complement component 3 1.626
HAMP hepcidin antimicrobial peptide 1.624
CD40LG CD40 ligand 1.621
NOS2 nitric oxide synthase 2, inducible 1.62
COL1A1 collagen, type I, alpha 1 1.619
TBL1X transducin (beta)-like 1X-linked 1.617
CCL24 chemokine (C-C motif) ligand 24 1.614
CD69 CD69 molecule 1.614
BCL2 B-cell CLL/lymphoma 2 1.612
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 1.612
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.608
CLEC7A C-type lectin domain family 7, member A 1.603
COLEC11 collectin sub-family member 11 1.6
CD28 CD28 molecule 1.599
INS insulin 1.599
ATAD1 ATPase family, AAA domain containing 1 1.596
ICOS inducible T-cell co-stimulator 1.595
INKA2 inka box actin regulator 2 1.59
IL7 interleukin 7 1.588
CHIA chitinase, acidic 1.586
GPX8 glutathione peroxidase 8 (putative) 1.583
ACTB actin, beta 1.578
GPX3 glutathione peroxidase 3 1.578
CXCL9 chemokine (C-X-C motif) ligand 9 1.577
HDAC9 histone deacetylase 9 1.577
CXCR5 chemokine (C-X-C motif) receptor 5 1.577
ICAM1 intercellular adhesion molecule 1 1.575
GPX7 glutathione peroxidase 7 1.572
GPX5 glutathione peroxidase 5 1.571
GPX6 glutathione peroxidase 6 1.569
PDE5A phosphodiesterase 5A, cGMP-specific 1.569
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.567
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.564
GPX2 glutathione peroxidase 2 1.563
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.563
ATP13A3 ATPase type 13A3 1.555
JUN jun proto-oncogene 1.553
NANOS1 nanos homolog 1 (Drosophila) 1.552
TLR7 toll-like receptor 7 1.546
IFNGR1 interferon gamma receptor 1 1.543
CXCR4 chemokine (C-X-C motif) receptor 4 1.543
CLEC6A C-type lectin domain family 6, member A 1.541
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.53
ACE angiotensin I converting enzyme 1.529
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 1.523
SELL selectin L 1.523
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.522
TFRC transferrin receptor 1.521
CD274 CD274 molecule 1.52
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.516
LAP3 leucine aminopeptidase 3 1.51
LGALS3 lectin, galactoside-binding, soluble, 3 1.508
PDCD1LG2 programmed cell death 1 ligand 2 1.502
CD68 CD68 molecule 1.5
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.498
MYH14 myosin, heavy chain 14, non-muscle 1.494
SMAD4 SMAD family member 4 1.486
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.485
CCL17 chemokine (C-C motif) ligand 17 1.485
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.481
TAC1 tachykinin, precursor 1 1.478
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.477
CDC42SE1 CDC42 small effector 1 1.472
MBL2 mannose-binding lectin (protein C) 2, soluble 1.469
SMAD9 SMAD family member 9 1.467
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.467
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.467
CHIT1 chitinase 1 (chitotriosidase) 1.466
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.464
NELFCD negative elongation factor complex member C/D 1.464
ANXA8 annexin A8 1.463
IL15 interleukin 15 1.463
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.457
MMP2 matrix metallopeptidase 2 1.455
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.453
CBS cystathionine-beta-synthase 1.453
ORM2 orosomucoid 2 1.449
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.448
CXCR3 chemokine (C-X-C motif) receptor 3 1.445
IL23A interleukin 23, alpha subunit p19 1.441
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.44
FASLG Fas ligand (TNF superfamily, member 6) 1.432
CAV1 caveolin 1, caveolae protein, 22kDa 1.431
ENG endoglin 1.428
CD44 CD44 molecule (Indian blood group) 1.428
IFNB1 interferon, beta 1, fibroblast 1.426
TMEM37 transmembrane protein 37 1.425
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.423
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.42
GDF2 growth differentiation factor 2 1.415
CALR calreticulin 1.414
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.413
GSTM1 glutathione S-transferase mu 1 1.412
THBS3 thrombospondin 3 1.412
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.41
CTSD cathepsin D 1.408
NLRP3 NLR family, pyrin domain containing 3 1.407
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 1.406
CD27 CD27 molecule 1.4
EDNRB endothelin receptor type B 1.4
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.393
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.393
PGK2 phosphoglycerate kinase 2 1.391
IL17RA interleukin 17 receptor A 1.391
PRF1 perforin 1 (pore forming protein) 1.389
PLG plasminogen 1.388
F3 coagulation factor III (thromboplastin, tissue factor) 1.386
ORM1 orosomucoid 1 1.384
AOC3 amine oxidase, copper containing 3 1.384
TLR1 toll-like receptor 1 1.383
TACR1 tachykinin receptor 1 1.38
YME1L1 YME1-like 1 ATPase 1.377
IL7R interleukin 7 receptor 1.372
CCL22 chemokine (C-C motif) ligand 22 1.369
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.367
CD59 CD59 molecule, complement regulatory protein 1.367
CCR3 chemokine (C-C motif) receptor 3 1.367
CTRB2 chymotrypsinogen B2 1.365
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.364
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.364
EGF epidermal growth factor 1.363
RETN resistin 1.362
ICOSLG inducible T-cell co-stimulator ligand 1.36
CTRB1 chymotrypsinogen B1 1.359
LOC102723996 ICOS ligand 1.359
NANOS2 nanos homolog 2 (Drosophila) 1.357
SPP1 secreted phosphoprotein 1 1.355
NPPB natriuretic peptide B 1.355
HMGB1 high mobility group box 1 1.351
MMP12 matrix metallopeptidase 12 1.35
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.35
SMC1A structural maintenance of chromosomes 1A 1.35
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.347
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 1.345
SST somatostatin 1.343
MAPK3 mitogen-activated protein kinase 3 1.341
KNG1 kininogen 1 1.338
ACHE acetylcholinesterase (Yt blood group) 1.337
POU5F2 POU domain class 5, transcription factor 2 1.332
SYK spleen tyrosine kinase 1.332
CSF1 colony stimulating factor 1 (macrophage) 1.33
CD276 CD276 molecule 1.327
HDAC1 histone deacetylase 1 1.325
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 1.323
PIWIL4 piwi-like RNA-mediated gene silencing 4 1.323
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.322
IRF4 interferon regulatory factor 4 1.321
CALML5 calmodulin-like 5 1.317
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.315
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.314
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.314
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.314
G6PD glucose-6-phosphate dehydrogenase 1.314
CALML6 calmodulin-like 6 1.313
CALML4 calmodulin-like 4 1.313
VCAM1 vascular cell adhesion molecule 1 1.312
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.31
CALML3 calmodulin-like 3 1.31
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.308
SCARB1 scavenger receptor class B, member 1 1.308
IL1R1 interleukin 1 receptor, type I 1.308
H2BC21 H2B clustered histone 21 1.307
CTSF cathepsin F 1.306
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.306
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.302
THBS1 thrombospondin 1 1.3
BACE1 beta-site APP-cleaving enzyme 1 1.3
IFNA2 interferon, alpha 2 1.298
EDNRA endothelin receptor type A 1.298
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.298
TBX4 T-box 4 1.296
EID2 EP300 interacting inhibitor of differentiation 2 1.29
CD36 CD36 molecule (thrombospondin receptor) 1.282
IL17F interleukin 17F 1.282
LBP lipopolysaccharide binding protein 1.281
CTSZ cathepsin Z 1.28
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.279
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.274
CYB5A cytochrome b5 type A (microsomal) 1.273
IL22RA2 interleukin 22 receptor, alpha 2 1.272
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.269
CD63 CD63 molecule 1.269
VIP vasoactive intestinal peptide 1.268
IFNA17 interferon, alpha 17 1.268
SCARB2 scavenger receptor class B, member 2 1.268
A2M alpha-2-macroglobulin 1.268
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.267
ZFYVE1 zinc finger, FYVE domain containing 1 1.264
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.264
LOX lysyl oxidase 1.263
OAT ornithine aminotransferase 1.263
COL3A1 collagen, type III, alpha 1 1.262
EGFR epidermal growth factor receptor 1.261
TIMP2 TIMP metallopeptidase inhibitor 2 1.261
CD34 CD34 molecule 1.258
PRDX1 peroxiredoxin 1 1.258
ICAM3 intercellular adhesion molecule 3 1.256
PNP purine nucleoside phosphorylase 1.255
LTA lymphotoxin alpha 1.253
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.252
CD38 CD38 molecule 1.25
RAG1 recombination activating gene 1 1.247
PCNA proliferating cell nuclear antigen 1.246
FGFR3 fibroblast growth factor receptor 3 1.243
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.24
CD5 CD5 molecule 1.24
CD163 CD163 molecule 1.24
VWF von Willebrand factor 1.239
DICER1 dicer 1, ribonuclease type III 1.239
CP ceruloplasmin (ferroxidase) 1.235
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.234
MPO myeloperoxidase 1.233
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.231
ELN elastin 1.229
IDO1 indoleamine 2,3-dioxygenase 1 1.229
SIRT2 sirtuin 2 1.229
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.229
TLR6 toll-like receptor 6 1.225
BAX BCL2-associated X protein 1.225
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1 1.221
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.217
CXCL11 chemokine (C-X-C motif) ligand 11 1.214
SELE selectin E 1.213
UPP2 uridine phosphorylase 2 1.212
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.211
IL25 interleukin 25 1.211
CDKN2A cyclin-dependent kinase inhibitor 2A 1.209
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.208
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 1.208
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.208
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.207
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 1.206
CYCS cytochrome c, somatic 1.204
DNAH8 dynein, axonemal, heavy chain 8 1.204
IGF1 insulin-like growth factor 1 (somatomedin C) 1.203
CCRL2 chemokine (C-C motif) receptor-like 2 1.202
JAK2 Janus kinase 2 1.199
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.199
PTEN phosphatase and tensin homolog 1.199
BCL6 B-cell CLL/lymphoma 6 1.198
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.193
CCR6 chemokine (C-C motif) receptor 6 1.193
RNASET2 ribonuclease T2 1.188
NUTF2 nuclear transport factor 2 1.188
MRGPRE MAS-related GPR, member E 1.187
IFNA13 interferon, alpha 13 1.186
ELANE elastase, neutrophil expressed 1.185
IFNA8 interferon, alpha 8 1.18
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.179
DROSHA drosha, ribonuclease type III 1.178
IFNA5 interferon, alpha 5 1.178
RHOA ras homolog family member A 1.178
TPT1 tumor protein, translationally-controlled 1 1.178
HMOX1 heme oxygenase 1 1.177
RORC RAR-related orphan receptor C 1.176
KRT20 keratin 20, type I 1.176
IFNA4 interferon, alpha 4 1.175
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.173
CAMP cathelicidin antimicrobial peptide 1.173
IFNA14 interferon, alpha 14 1.172
IFNA7 interferon, alpha 7 1.172
IFNA16 interferon, alpha 16 1.172
CXORF66 chromosome X open reading frame 66 1.172
SOCS3 suppressor of cytokine signaling 3 1.171
IFNA10 interferon, alpha 10 1.171
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.171
IFNA21 interferon, alpha 21 1.171
HP haptoglobin 1.171
IFNA6 interferon, alpha 6 1.171
MMP1 matrix metallopeptidase 1 1.17
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.169
NOS3 nitric oxide synthase 3 (endothelial cell) 1.169
CLMP CXADR-like membrane protein 1.168
ANXA5 annexin A5 1.167
CXCL13 chemokine (C-X-C motif) ligand 13 1.162
IRAK1 interleukin-1 receptor-associated kinase 1 1.16
CXCL12 chemokine (C-X-C motif) ligand 12 1.158
PDCD1 programmed cell death 1 1.158
CES2 carboxylesterase 2 1.153
FGF7 fibroblast growth factor 7 1.152
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.152
TLR5 toll-like receptor 5 1.151
SOCS1 suppressor of cytokine signaling 1 1.15
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.149
TSPAN1 tetraspanin 1 1.149
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.149
MMP13 matrix metallopeptidase 13 1.149
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.149
TLR8 toll-like receptor 8 1.145
CXCR2 chemokine (C-X-C motif) receptor 2 1.144
HDAC6 histone deacetylase 6 1.144
CSF3 colony stimulating factor 3 (granulocyte) 1.143
FGF22 fibroblast growth factor 22 1.143
CCR7 chemokine (C-C motif) receptor 7 1.143
MB myoglobin 1.142
HMGA2 high mobility group AT-hook 2 1.142
FGF16 fibroblast growth factor 16 1.141
FGF6 fibroblast growth factor 6 1.141
ACE2 angiotensin I converting enzyme 2 1.141
FGF9 fibroblast growth factor 9 1.14
TCF15 transcription factor 15 (basic helix-loop-helix) 1.139
FGF20 fibroblast growth factor 20 1.139
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.139
FGF10 fibroblast growth factor 10 1.138
FGF3 fibroblast growth factor 3 1.136
FGF17 fibroblast growth factor 17 1.136
TXNDC9 thioredoxin domain containing 9 1.135
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.134
IRF1 interferon regulatory factor 1 1.134
FGF5 fibroblast growth factor 5 1.133
FGF18 fibroblast growth factor 18 1.133
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.132
CCR1 chemokine (C-C motif) receptor 1 1.13
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.129
CXCL2 chemokine (C-X-C motif) ligand 2 1.129
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.128
CLEC4E C-type lectin domain family 4, member E 1.127
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.127
FGF4 fibroblast growth factor 4 1.126
IL27RA interleukin 27 receptor, alpha 1.125
SDC1 syndecan 1 1.124
PTGDR2 prostaglandin D2 receptor 2 1.124
H3-5 H3.5 histone 1.121
COL1A2 collagen, type I, alpha 2 1.121
CYBB cytochrome b-245, beta polypeptide 1.121
H3-4 H3.4 histone, cluster member 1.12
NCAM1 neural cell adhesion molecule 1 1.12
APOE apolipoprotein E 1.12
FGF8 fibroblast growth factor 8 (androgen-induced) 1.118
UPP1 uridine phosphorylase 1 1.118
REN renin 1.116
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.115
DHODH dihydroorotate dehydrogenase (quinone) 1.114
H3C13 H3 clustered histone 13 1.114
TGFB2 transforming growth factor, beta 2 1.114
PGK1 phosphoglycerate kinase 1 1.113
ESR1 estrogen receptor 1 1.113
NOD2 nucleotide-binding oligomerization domain containing 2 1.111
KRAS Kirsten rat sarcoma viral oncogene homolog 1.11
CES1 carboxylesterase 1 1.11
H3C12 H3 clustered histone 12 1.109
BCL2L1 BCL2-like 1 1.108
H3-3B H3.3 histone B 1.108
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.107
AIM2 absent in melanoma 2 1.106
SMN1 survival of motor neuron 1, telomeric 1.104
CXCR6 chemokine (C-X-C motif) receptor 6 1.103
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.102
FGF2 fibroblast growth factor 2 (basic) 1.102
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.102
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.101
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.1
HAVCR2 hepatitis A virus cellular receptor 2 1.098
NFE2L2 nuclear factor, erythroid 2-like 2 1.097
IFNL3 interferon, lambda 3 1.096
LTF lactotransferrin 1.094
KRT7 keratin 7, type II 1.094
PLK1 polo-like kinase 1 1.09
SOX17 SRY (sex determining region Y)-box 17 1.086
SIRT1 sirtuin 1 1.086
TIMD4 T-cell immunoglobulin and mucin domain containing 4 1.085
IL4I1 interleukin 4 induced 1 1.082
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.082
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.081
MMP3 matrix metallopeptidase 3 1.081
GSDMD gasdermin D 1.081
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.078
JAK1 Janus kinase 1 1.077
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.076
FLNB filamin B, beta 1.076
CD83 CD83 molecule 1.075
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.073
IL17RB interleukin 17 receptor B 1.071
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.071
EPO erythropoietin 1.07
MRGPRF MAS-related GPR, member F 1.068
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.067
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.067
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.066
PFN4 profilin family, member 4 1.066
IRF3 interferon regulatory factor 3 1.066
IL2RA interleukin 2 receptor, alpha 1.063
IL27 interleukin 27 1.063
H4C7 H4 clustered histone 7 1.062
PFN3 profilin 3 1.061
IL19 interleukin 19 1.061
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.06
BST2 bone marrow stromal cell antigen 2 1.059
RIOK2 RIO kinase 2 1.058
PGLYRP1 peptidoglycan recognition protein 1 1.056
TGFA transforming growth factor, alpha 1.055
CCR9 chemokine (C-C motif) receptor 9 1.053
CA1 carbonic anhydrase I 1.053
H2AC20 H2A clustered histone 20 1.052
H2AC18 H2A clustered histone 18 1.051
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.05
PECAM1 platelet/endothelial cell adhesion molecule 1 1.05
TERT telomerase reverse transcriptase 1.05
H4C6 H4 clustered histone 6 1.047
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.045
PCSK2 proprotein convertase subtilisin/kexin type 2 1.045
IL21R interleukin 21 receptor 1.045
KLK3 kallikrein-related peptidase 3 1.044
PTCH2 patched 2 1.042
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.041
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.038
ERBB2 erb-b2 receptor tyrosine kinase 2 1.037
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.036
TCHH trichohyalin 1.036
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.035
KRT5 keratin 5, type II 1.034
CD9 CD9 molecule 1.033
CCL20 chemokine (C-C motif) ligand 20 1.031
IL23R interleukin 23 receptor 1.031
CD81 CD81 molecule 1.026
LDLR low density lipoprotein receptor 1.025
STAT5A signal transducer and activator of transcription 5A 1.024
TTR transthyretin 1.023
PTGIS prostaglandin I2 (prostacyclin) synthase 1.022
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.019
KRT76 keratin 76, type II 1.018
PKM pyruvate kinase, muscle 1.017
CCND1 cyclin D1 1.015
IL12RB1 interleukin 12 receptor, beta 1 1.012
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.011
HSPB3 heat shock 27kDa protein 3 1.011
IL22RA1 interleukin 22 receptor, alpha 1 1.009
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1.008
IL17B interleukin 17B 1.008
FAS Fas cell surface death receptor 1.008
TGFB3 transforming growth factor, beta 3 1.007
DHFR2 dihydrofolate reductase 2 1.006
ECE1 endothelin converting enzyme 1 1.005
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.004
IL12RB2 interleukin 12 receptor, beta 2 1.004
NUMA1 nuclear mitotic apparatus protein 1 1.004
CA14 carbonic anhydrase XIV 1.001
FLNC filamin C, gamma 1.0