Schistosomiasis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria. (Human Disease Ontology, DOID_1395)
External Link https://www.disgenet.org/browser/0/1/0/C0036323
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Genes

139 genes associated with the disease Schistosomiasis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACHE acetylcholinesterase (Yt blood group)
APOE apolipoprotein E
ARG1 arginase 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
C2 complement component 2
CA1 carbonic anhydrase I
CCL24 chemokine (C-C motif) ligand 24
CCL7 chemokine (C-C motif) ligand 7
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD28 CD28 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD63 CD63 molecule
CD86 CD86 molecule
CDK2 cyclin-dependent kinase 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CHP1 calcineurin-like EF-hand protein 1
COLEC11 collectin sub-family member 11
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSD cathepsin D
CXCR5 chemokine (C-X-C motif) receptor 5
DCTN3 dynactin 3 (p22)
DHODH dihydroorotate dehydrogenase (quinone)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGFR epidermal growth factor receptor
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FBRS fibrosin
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FUZ fuzzy planar cell polarity protein
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC8 histone deacetylase 8
HLA-A major histocompatibility complex, class I, A
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
HSPA14 heat shock 70kDa protein 14
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICOS inducible T-cell co-stimulator
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL21 interleukin 21
IL22 interleukin 22
IL23R interleukin 23 receptor
IL33 interleukin 33
IL4 interleukin 4
IL4I1 interleukin 4 induced 1
IL4R interleukin 4 receptor
IL5 interleukin 5
IL7 interleukin 7
IL9 interleukin 9
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LAMP3 lysosomal-associated membrane protein 3
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LSAMP limbic system-associated membrane protein
LYPD5 LY6/PLAUR domain containing 5
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MICA MHC class I polypeptide-related sequence A
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRPL28 mitochondrial ribosomal protein L28
MTA1 metastasis associated 1
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBEAL2 neurobeachin-like 2
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NXT1 nuclear transport factor 2-like export factor 1
PC pyruvate carboxylase
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD10 programmed cell death 10
PDE4A phosphodiesterase 4A, cAMP-specific
PHB2 prohibitin 2
PLAU plasminogen activator, urokinase
PLG plasminogen
POMC proopiomelanocortin
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDX1 peroxiredoxin 1
RAB40B RAB40B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RARA retinoic acid receptor, alpha
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RRBP1 ribosome binding protein 1
SELENOT selenoprotein T
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFXN1 sideroflexin 1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMAD7 SMAD family member 7
SOD1 superoxide dismutase 1, soluble
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STH saitohin
STOML1 stomatin (EPB72)-like 1
SUB1 SUB1 homolog (S. cerevisiae)
SUCO SUN domain containing ossification factor
SYTL1 synaptotagmin-like 1
TACR1 tachykinin receptor 1
THBS2 thrombospondin 2
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TNF tumor necrosis factor
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
TXN thioredoxin
TXNIP thioredoxin interacting protein
TXNRD3 thioredoxin reductase 3
VEGFA vascular endothelial growth factor A