Schizophrenia Gene Set

Dataset DISEASES Curated Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.|A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. (Experimental Factor Ontology, EFO_0000692)
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Genes

16 genes involed in the disease Schizophrenia from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

Symbol Name Standardized Value
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 5.0
ZDHHC8 zinc finger, DHHC-type containing 8 5.0
C4A complement component 4A (Rodgers blood group) 5.0
AKT1 v-akt murine thymoma viral oncogene homolog 1 5.0
OLIG2 oligodendrocyte lineage transcription factor 2 5.0
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 5.0
RTN4R reticulon 4 receptor 5.0
NRXN1 neurexin 1 5.0
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 5.0
SYN2 synapsin II 5.0
DGCR2 DiGeorge syndrome critical region gene 2 5.0
DGCR8 DGCR8 microprocessor complex subunit 5.0
DRD2 dopamine receptor D2 5.0
COMT catechol-O-methyltransferase 5.0
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 5.0
TOP3B topoisomerase (DNA) III beta 5.0