Schwannomatosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

299 genes co-occuring with the disease Schwannomatosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
NF2 neurofibromin 2 (merlin) 4.0
LZTR1 leucine-zipper-like transcription regulator 1 3.35
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 3.267
NF1 neurofibromin 1 3.116
RDX radixin 2.713
MSN moesin 2.669
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 2.541
EZR ezrin 2.525
LATS1 large tumor suppressor kinase 1 2.471
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2.456
EPB41 erythrocyte membrane protein band 4.1 2.419
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 2.367
SAV1 salvador family WW domain containing protein 1 2.28
TCHP trichoplein, keratin filament binding 2.238
H3C12 H3 clustered histone 12 2.17
H3-3B H3.3 histone B 2.139
H3-4 H3.4 histone, cluster member 2.138
H3-5 H3.5 histone 2.138
H3C13 H3 clustered histone 13 2.132
WWC1 WW and C2 domain containing 1 2.104
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.102
LATS2 large tumor suppressor kinase 2 2.08
CDKN2A cyclin-dependent kinase inhibitor 2A 2.029
AMOT angiomotin 2.026
CTXN3 cortexin 3 2.006
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.999
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.982
DCAF1 DDB1 and CUL4 associated factor 1 1.982
MOB1A MOB kinase activator 1A 1.981
MSI1 musashi RNA-binding protein 1 1.979
GFER growth factor, augmenter of liver regeneration 1.965
SOX10 SRY (sex determining region Y)-box 10 1.912
EPB41L3 erythrocyte membrane protein band 4.1-like 3 1.901
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 1.892
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.889
CHD3 chromodomain helicase DNA binding protein 3 1.885
RBBP4 retinoblastoma binding protein 4 1.883
H2AC20 H2A clustered histone 20 1.88
H2AC18 H2A clustered histone 18 1.879
YAP1 Yes-associated protein 1 1.871
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.856
TP53 tumor protein p53 1.841
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.814
H2AZ1 H2A.Z variant histone 1 1.805
STK3 serine/threonine kinase 3 1.793
CUL3 cullin 3 1.791
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.787
SUFU suppressor of fused homolog (Drosophila) 1.781
WWTR1 WW domain containing transcription regulator 1 1.775
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.758
STK4 serine/threonine kinase 4 1.757
COQ6 coenzyme Q6 monooxygenase 1.75
MYB v-myb avian myeloblastosis viral oncogene homolog 1.741
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.736
EGFR epidermal growth factor receptor 1.735
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 1.723
SUZ12 SUZ12 polycomb repressive complex 2 subunit 1.717
STK24 serine/threonine kinase 24 1.716
MED28 mediator complex subunit 28 1.714
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.699
ARID1B AT rich interactive domain 1B (SWI1-like) 1.693
ABI3 ABI family, member 3 1.671
ARID1A AT rich interactive domain 1A (SWI-like) 1.664
KLF4 Kruppel-like factor 4 (gut) 1.662
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.662
MOB1B MOB kinase activator 1B 1.651
SPRED1 sprouty-related, EVH1 domain containing 1 1.651
SRCAP Snf2-related CREBBP activator protein 1.649
MED18 mediator complex subunit 18 1.642
BANF1 barrier to autointegration factor 1 1.633
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.629
PTEN phosphatase and tensin homolog 1.628
LARP1 La ribonucleoprotein domain family, member 1 1.619
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.604
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.588
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.581
H2BC21 H2B clustered histone 21 1.58
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.575
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.568
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.563
ZNF346 zinc finger protein 346 1.557
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.544
SEPTIN3 septin 3 1.538
PBRM1 polybromo 1 1.515
SSX2 synovial sarcoma, X breakpoint 2 1.5
VGLL4 vestigial-like family member 4 1.491
CD34 CD34 molecule 1.485
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.48
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.479
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 1.475
CCND1 cyclin D1 1.472
CD44 CD44 molecule (Indian blood group) 1.472
SH3PXD2A SH3 and PX domains 2A 1.472
CABIN1 calcineurin binding protein 1 1.467
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 1.464
TAOK1 TAO kinase 1 1.452
SHH sonic hedgehog 1.452
ADGRL1 adhesion G protein-coupled receptor L1 1.45
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.449
SCHIP1 schwannomin interacting protein 1 1.445
TEAD2 TEA domain family member 2 1.444
TERT telomerase reverse transcriptase 1.438
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 1.437
MAP2K1 mitogen-activated protein kinase kinase 1 1.434
NRG1 neuregulin 1 1.431
LGALS4 lectin, galactoside-binding, soluble, 4 1.427
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.427
MORC2 MORC family CW-type zinc finger 2 1.424
SOS1 son of sevenless homolog 1 (Drosophila) 1.419
PHF10 PHD finger protein 10 1.41
CDC42 cell division cycle 42 1.402
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.402
TEAD4 TEA domain family member 4 1.4
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.398
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.394
ERBB2 erb-b2 receptor tyrosine kinase 2 1.392
EGF epidermal growth factor 1.388
ERBB3 erb-b2 receptor tyrosine kinase 3 1.387
RING1 ring finger protein 1 1.386
PXN paxillin 1.383
SGSM1 small G protein signaling modulator 1 1.382
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.381
GLYATL1 glycine-N-acyltransferase-like 1 1.379
CCN2 cellular communication network factor 2 1.377
TAAR9 trace amine associated receptor 9 (gene/pseudogene) 1.369
LRRC70 leucine rich repeat containing 70 1.368
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.364
AGO4 argonaute RISC catalytic component 4 1.353
MRAS muscle RAS oncogene homolog 1.349
SCRIB scribbled planar cell polarity protein 1.349
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.348
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 1.346
HDAC9 histone deacetylase 9 1.342
ZNF629 zinc finger protein 629 1.339
ZNF501 zinc finger protein 501 1.339
ZNF44 zinc finger protein 44 1.338
ZNF763 zinc finger protein 763 1.337
ZNF436 zinc finger protein 436 1.337
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.331
ZNF569 zinc finger protein 569 1.329
MEN1 multiple endocrine neoplasia I 1.324
PTK2 protein tyrosine kinase 2 1.324
HRAS Harvey rat sarcoma viral oncogene homolog 1.324
CCN1 cellular communication network factor 1 1.32
ADGRL2 adhesion G protein-coupled receptor L2 1.32
TSC2 tuberous sclerosis 2 1.318
AMOTL2 angiomotin like 2 1.317
ACTL6A actin-like 6A 1.316
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.315
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 1.311
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.308
TLN2 talin 2 1.301
SPTBN1 spectrin, beta, non-erythrocytic 1 1.299
CDK4 cyclin-dependent kinase 4 1.299
TAOK2 TAO kinase 2 1.294
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.291
DPF2 D4, zinc and double PHD fingers family 2 1.284
CIAO3 cytosolic iron-sulfur assembly component 3 1.278
RIT1 Ras-like without CAAX 1 1.262
BMI1 BMI1 proto-oncogene, polycomb ring finger 1.262
GLI1 GLI family zinc finger 1 1.26
AEBP2 AE binding protein 2 1.257
ERBB4 erb-b2 receptor tyrosine kinase 4 1.257
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 1.254
COMMD3-BMI1 COMMD3-BMI1 readthrough 1.253
KRAS Kirsten rat sarcoma viral oncogene homolog 1.253
NFYB nuclear transcription factor Y, beta 1.252
BRD7 bromodomain containing 7 1.245
TLN1 talin 1 1.236
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.234
EWSR1 EWS RNA-binding protein 1 1.231
SMO smoothened, frizzled class receptor 1.231
DCLK3 doublecortin-like kinase 3 1.229
PTCH1 patched 1 1.228
RASA2 RAS p21 protein activator 2 1.224
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.223
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.223
YEATS4 YEATS domain containing 4 1.219
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.219
GFAP glial fibrillary acidic protein 1.218
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.217
SCARF2 scavenger receptor class F, member 2 1.215
BRCA1 breast cancer 1, early onset 1.214
PATJ PATJ crumbs cell polarity complex component 1.214
TGFB1 transforming growth factor, beta 1 1.212
MORC1 MORC family CW-type zinc finger 1 1.212
NGF nerve growth factor (beta polypeptide) 1.205
MET MET proto-oncogene, receptor tyrosine kinase 1.203
TP73 tumor protein p73 1.203
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.199
H4C7 H4 clustered histone 7 1.195
HNMT histamine N-methyltransferase 1.194
CAMTA1 calmodulin binding transcription activator 1 1.193
EZHIP EZH inhibitory protein 1.193
DICER1 dicer 1, ribonuclease type III 1.182
FRMD1 FERM domain containing 1 1.181
TADA2B transcriptional adaptor 2B 1.178
RHOA ras homolog family member A 1.178
H3C6 H3 clustered histone 6 1.178
KDR kinase insert domain receptor 1.177
H3C3 H3 clustered histone 3 1.176
S100B S100 calcium binding protein B 1.176
SOS2 son of sevenless homolog 2 (Drosophila) 1.175
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.172
MAPK3 mitogen-activated protein kinase 3 1.172
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.168
H4C6 H4 clustered histone 6 1.164
SOX2 SRY (sex determining region Y)-box 2 1.162
JUN jun proto-oncogene 1.161
AURKA aurora kinase A 1.159
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.158
DGCR8 DGCR8 microprocessor complex subunit 1.155
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 1.154
HOXA6 homeobox A6 1.143
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.142
NOTCH2 notch 2 1.142
MAMLD1 mastermind-like domain containing 1 1.138
C2ORF88 chromosome 2 open reading frame 88 1.137
DNAH8 dynein, axonemal, heavy chain 8 1.136
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 1.135
AGO1 argonaute RISC catalytic component 1 1.13
CRYBB2 crystallin, beta B2 1.129
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.127
DIAPH1 diaphanous-related formin 1 1.124
BICRA BRD4 interacting chromatin remodeling complex associated protein 1.116
AJUBA ajuba LIM protein 1.113
AP1B1 adaptor-related protein complex 1, beta 1 subunit 1.109
NDRG2 NDRG family member 2 1.107
ALPK2 alpha-kinase 2 1.107
PMP22 peripheral myelin protein 22 1.103
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.103
SIRAL1 SIR2 antiphage like 1 1.103
EED embryonic ectoderm development 1.101
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.095
CALB2 calbindin 2 1.091
RRAS related RAS viral (r-ras) oncogene homolog 1.09
PGR progesterone receptor 1.086
HDAC1 histone deacetylase 1 1.079
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.079
TRIOBP TRIO and F-actin binding protein 1.079
RNMT RNA (guanine-7-) methyltransferase 1.071
EIF3C eukaryotic translation initiation factor 3, subunit C 1.065
AMOTL1 angiomotin like 1 1.063
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.062
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.062
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.061
ASRGL1 asparaginase like 1 1.061
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 1.06
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.059
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.058
ACTB actin, beta 1.057
DPF3 D4, zinc and double PHD fingers, family 3 1.054
RB1 retinoblastoma 1 1.051
MAP2K2 mitogen-activated protein kinase kinase 2 1.05
DDB1 damage-specific DNA binding protein 1, 127kDa 1.047
SETD2 SET domain containing 2 1.046
ARHGAP17 Rho GTPase activating protein 17 1.046
HDAC2 histone deacetylase 2 1.044
FRMD6 FERM domain containing 6 1.043
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.041
KDM6A lysine (K)-specific demethylase 6A 1.039
CD274 CD274 molecule 1.038
KAT2B K(lysine) acetyltransferase 2B 1.037
PXDNL peroxidasin-like 1.037
PRH1 proline-rich protein HaeIII subfamily 1 1.036
NPIPB11 nuclear pore complex interacting protein family, member B11 1.036
PXDN peroxidasin 1.035
PWWP2B PWWP domain containing 2B 1.034
WASL Wiskott-Aldrich syndrome-like 1.032
NEFH neurofilament, heavy polypeptide 1.03
STK38 serine/threonine kinase 38 1.027
WNK2 WNK lysine deficient protein kinase 2 1.027
PEBP1 phosphatidylethanolamine binding protein 1 1.026
BIRC5 baculoviral IAP repeat containing 5 1.023
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.023
SRRT serrate, RNA effector molecule 1.022
IL6 interleukin 6 1.021
CKMT1A creatine kinase, mitochondrial 1A 1.02
NGFR nerve growth factor receptor 1.02
CDKN3 cyclin-dependent kinase inhibitor 3 1.018
FGF2 fibroblast growth factor 2 (basic) 1.017
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.016
ALK anaplastic lymphoma receptor tyrosine kinase 1.013
MYPN myopalladin 1.013
FLT1 fms-related tyrosine kinase 1 1.013
GLI2 GLI family zinc finger 2 1.011
BRD9 bromodomain containing 9 1.011
MITF microphthalmia-associated transcription factor 1.011
CDK6 cyclin-dependent kinase 6 1.01
VGLL1 vestigial-like family member 1 1.01
CRY2 cryptochrome circadian clock 2 1.009
SMIM20 small integral membrane protein 20 1.007
BRD4 bromodomain containing 4 1.007
NCOR1 nuclear receptor corepressor 1 1.002
GRB2 growth factor receptor-bound protein 2 1.002
GJE1 gap junction protein, epsilon 1, 23kDa 1.002
CRB2 crumbs family member 2 1.002
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 1.002
VGLL3 vestigial-like family member 3 1.0