Sciatic Neuropathy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description PRISM. (Human Disease Ontology, DOID_11446)
External Link https://www.disgenet.org/browser/0/1/0/C0149940
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Genes

113 genes associated with the disease Sciatic Neuropathy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP12 A kinase (PRKA) anchor protein 12
AMIGO3 adhesion molecule with Ig-like domain 3
APOA1 apolipoprotein A-I
APOE apolipoprotein E
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
C3 complement component 3
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALCA calcitonin-related polypeptide alpha
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CNR2 cannabinoid receptor 2 (macrophage)
CRCP CGRP receptor component
CREB1 cAMP responsive element binding protein 1
CRH corticotropin releasing hormone
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBN1 drebrin 1
ELAVL4 ELAV like neuron-specific RNA binding protein 4
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FUBP1 far upstream element (FUSE) binding protein 1
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GFRA3 GDNF family receptor alpha 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HRH3 histamine receptor H3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAM3 junctional adhesion molecule 3
KARS1 lysyl-tRNA synthetase 1
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
LAMP2 lysosomal-associated membrane protein 2
LRP1 low density lipoprotein receptor-related protein 1
MAG myelin associated glycoprotein
MAP2 microtubule-associated protein 2
MC4R melanocortin 4 receptor
MMP9 matrix metallopeptidase 9
MPZ myelin protein zero
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH4 myosin, heavy chain 4, skeletal muscle
NEFH neurofilament, heavy polypeptide
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NF1 neurofibromin 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NLGN2 neuroligin 2
NLGN3 neuroligin 3
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRG1 neuregulin 1
NTS neurotensin
OPRL1 opiate receptor-like 1
PCNA proliferating cell nuclear antigen
PCSK5 proprotein convertase subtilisin/kexin type 5
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PMP22 peripheral myelin protein 22
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTAFR platelet-activating factor receptor
PTN pleiotrophin
QARS1 glutaminyl-tRNA synthetase 1
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RANGAP1 Ran GTPase activating protein 1
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REG3A regenerating islet-derived 3 alpha
RGMA repulsive guidance molecule family member a
RPSA ribosomal protein SA
RXRA retinoid X receptor, alpha
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SNW1 SNW domain containing 1
SOD1 superoxide dismutase 1, soluble
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B