Scleroderma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A rheumatic disease and collagen disease that involves the abnormal growth of connective tissue, which supports the skin and internal organs. (Human Disease Ontology, DOID_419)
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Genes

1497 genes co-occuring with the disease Scleroderma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TGFB1 transforming growth factor, beta 1 3.227
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 3.156
EXOSC10 exosome component 10 3.135
TRIM21 tripartite motif containing 21 3.037
IL6 interleukin 6 3.007
CENPB centromere protein B, 80kDa 2.981
CD4 CD4 molecule 2.924
TNF tumor necrosis factor 2.918
CCN2 cellular communication network factor 2 2.917
IFNG interferon, gamma 2.848
IL1B interleukin 1, beta 2.833
EDN1 endothelin 1 2.831
IL17A interleukin 17A 2.83
IL4 interleukin 4 2.805
CRP C-reactive protein, pentraxin-related 2.784
IL13 interleukin 13 2.746
TSSK1B testis-specific serine kinase 1B 2.729
IL10 interleukin 10 2.725
CD8A CD8a molecule 2.719
FN1 fibronectin 1 2.716
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.665
RO60 Ro60, Y RNA binding protein 2.651
IL1A interleukin 1, alpha 2.641
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.615
FBL fibrillarin 2.611
CCL2 chemokine (C-C motif) ligand 2 2.599
IFIH1 interferon induced with helicase C domain 1 2.589
IFNA1 interferon, alpha 1 2.582
CXCL8 chemokine (C-X-C motif) ligand 8 2.567
IRF5 interferon regulatory factor 5 2.567
COL1A1 collagen, type I, alpha 1 2.567
SSB Sjogren syndrome antigen B (autoantigen La) 2.566
PRTN3 proteinase 3 2.555
SMAD3 SMAD family member 3 2.55
COL1A2 collagen, type I, alpha 2 2.544
SMAD2 SMAD family member 2 2.542
IL2 interleukin 2 2.535
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.527
ACE angiotensin I converting enzyme 2.526
MORC3 MORC family CW-type zinc finger 3 2.521
NPPB natriuretic peptide B 2.521
EDNRA endothelin receptor type A 2.518
STAT4 signal transducer and activator of transcription 4 2.481
TRIM33 tripartite motif containing 33 2.475
CD19 CD19 molecule 2.467
FOXP3 forkhead box P3 2.466
TOP1 topoisomerase (DNA) I 2.455
CXCL10 chemokine (C-X-C motif) ligand 10 2.448
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.447
CD34 CD34 molecule 2.433
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 2.429
MMP1 matrix metallopeptidase 1 2.426
TOP1MT topoisomerase (DNA) I, mitochondrial 2.419
UBTF upstream binding transcription factor, RNA polymerase I 2.417
CENPA centromere protein A 2.412
FBN1 fibrillin 1 2.396
ICAM1 intercellular adhesion molecule 1 2.395
VWF von Willebrand factor 2.379
PDE5A phosphodiesterase 5A, cGMP-specific 2.367
IL22 interleukin 22 2.348
ALB albumin 2.347
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.347
MUC1 mucin 1, cell surface associated 2.346
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.338
IL33 interleukin 33 2.338
TLR7 toll-like receptor 7 2.338
SFTPD surfactant protein D 2.337
MPO myeloperoxidase 2.334
IL5 interleukin 5 2.334
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.328
CKM creatine kinase, muscle 2.328
CKMT1B creatine kinase, mitochondrial 1B 2.327
CKB creatine kinase, brain 2.325
PF4 platelet factor 4 2.323
TLR4 toll-like receptor 4 2.321
TLR9 toll-like receptor 9 2.312
VCAM1 vascular cell adhesion molecule 1 2.311
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.311
PTPRC protein tyrosine phosphatase, receptor type, C 2.31
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.31
IL18 interleukin 18 2.304
TIMP1 TIMP metallopeptidase inhibitor 1 2.3
CD40LG CD40 ligand 2.273
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.266
TGFBR1 transforming growth factor, beta receptor 1 2.262
CD40 CD40 molecule, TNF receptor superfamily member 5 2.262
EXOSC9 exosome component 9 2.261
CENPS centromere protein S 2.261
ELN elastin 2.254
HARS1 histidyl-tRNA synthetase 1 2.248
PECAM1 platelet/endothelial cell adhesion molecule 1 2.245
SELE selectin E 2.245
IFNB1 interferon, beta 1, fibroblast 2.244
CXCR3 chemokine (C-X-C motif) receptor 3 2.242
TGFB2 transforming growth factor, beta 2 2.242
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.237
MMP9 matrix metallopeptidase 9 2.233
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.23
FOSL2 FOS-like antigen 2 2.224
CD28 CD28 molecule 2.222
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.22
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.218
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.201
BLK BLK proto-oncogene, Src family tyrosine kinase 2.198
STAT1 signal transducer and activator of transcription 1, 91kDa 2.195
COL3A1 collagen, type III, alpha 1 2.194
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.182
TNIP1 TNFAIP3 interacting protein 1 2.181
POSTN periostin, osteoblast specific factor 2.18
TGFB3 transforming growth factor, beta 3 2.176
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.173
CD86 CD86 molecule 2.167
CD80 CD80 molecule 2.166
OXCT1 3-oxoacid CoA transferase 1 2.165
CXCL9 chemokine (C-X-C motif) ligand 9 2.165
MMP3 matrix metallopeptidase 3 2.161
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.161
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.159
EDNRB endothelin receptor type B 2.157
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.154
FAM167A family with sequence similarity 167, member A 2.149
CCL5 chemokine (C-C motif) ligand 5 2.143
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.142
C3 complement component 3 2.137
FGF2 fibroblast growth factor 2 (basic) 2.133
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.133
FGF7 fibroblast growth factor 7 2.131
CD27 CD27 molecule 2.127
ENG endoglin 2.126
TBX21 T-box 21 2.125
LPAR1 lysophosphatidic acid receptor 1 2.119
TLR2 toll-like receptor 2 2.119
APOH apolipoprotein H (beta-2-glycoprotein I) 2.113
SMAD7 SMAD family member 7 2.11
IRF7 interferon regulatory factor 7 2.11
JAK1 Janus kinase 1 2.109
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 2.109
TLR3 toll-like receptor 3 2.107
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.106
CD163 CD163 molecule 2.106
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 2.105
REN renin 2.095
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.094
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.092
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 2.089
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.089
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.086
PPARG peroxisome proliferator-activated receptor gamma 2.086
TLR8 toll-like receptor 8 2.081
CSF3 colony stimulating factor 3 (granulocyte) 2.076
CCL3 chemokine (C-C motif) ligand 3 2.075
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.074
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.072
AGTR1 angiotensin II receptor, type 1 2.069
CXCR5 chemokine (C-X-C motif) receptor 5 2.061
THY1 Thy-1 cell surface antigen 2.059
CXCL12 chemokine (C-X-C motif) ligand 12 2.054
CCR6 chemokine (C-C motif) receptor 6 2.048
CXCL13 chemokine (C-X-C motif) ligand 13 2.047
THBS1 thrombospondin 1 2.045
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.043
CD68 CD68 molecule 2.039
PXDN peroxidasin 2.037
CDH5 cadherin 5, type 2 (vascular endothelium) 2.037
CENPC centromere protein C 2.035
EGF epidermal growth factor 2.035
FGF9 fibroblast growth factor 9 2.034
IL9 interleukin 9 2.034
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.033
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.033
FGF6 fibroblast growth factor 6 2.032
INS insulin 2.032
PXDNL peroxidasin-like 2.03
NUP210 nucleoporin 210kDa 2.029
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.029
FGF10 fibroblast growth factor 10 2.028
CXCR4 chemokine (C-X-C motif) receptor 4 2.027
FGF22 fibroblast growth factor 22 2.027
FGF18 fibroblast growth factor 18 2.026
CXCL11 chemokine (C-X-C motif) ligand 11 2.026
CAV1 caveolin 1, caveolae protein, 22kDa 2.025
FGF17 fibroblast growth factor 17 2.025
SPP1 secreted phosphoprotein 1 2.025
FGF16 fibroblast growth factor 16 2.024
FGF20 fibroblast growth factor 20 2.024
COL18A1 collagen, type XVIII, alpha 1 2.022
FGF5 fibroblast growth factor 5 2.022
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.021
TYK2 tyrosine kinase 2 2.018
FGF4 fibroblast growth factor 4 2.018
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.017
FGF3 fibroblast growth factor 3 2.016
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.012
RNPC3 RNA-binding region (RNP1, RRM) containing 3 2.012
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.012
FGF8 fibroblast growth factor 8 (androgen-induced) 2.01
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.01
IL7 interleukin 7 2.001
MMP2 matrix metallopeptidase 2 1.999
MX1 MX dynamin-like GTPase 1 1.999
MYD88 myeloid differentiation primary response 88 1.995
CCRL2 chemokine (C-C motif) receptor-like 2 1.994
MMP12 matrix metallopeptidase 12 1.993
NT5C1A 5'-nucleotidase, cytosolic IA 1.99
SMAD4 SMAD family member 4 1.986
NLRP3 NLR family, pyrin domain containing 3 1.983
JUN jun proto-oncogene 1.982
PSIP1 PC4 and SFRS1 interacting protein 1 1.981
PLG plasminogen 1.978
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.976
IFI44 interferon-induced protein 44 1.973
IFNA2 interferon, alpha 2 1.972
IL6R interleukin 6 receptor 1.971
JAK2 Janus kinase 2 1.969
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.969
F3 coagulation factor III (thromboplastin, tissue factor) 1.968
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.966
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.966
ACTB actin, beta 1.964
IRAK1 interleukin-1 receptor-associated kinase 1 1.963
PLD4 phospholipase D family, member 4 1.962
HLA-B major histocompatibility complex, class I, B 1.961
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.961
S100A4 S100 calcium binding protein A4 1.959
CCL4 chemokine (C-C motif) ligand 4 1.956
IL15 interleukin 15 1.953
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.953
IL17F interleukin 17F 1.951
TSLP thymic stromal lymphopoietin 1.95
DNASE1L3 deoxyribonuclease I-like 3 1.95
IL1R1 interleukin 1 receptor, type I 1.946
CCR2 chemokine (C-C motif) receptor 2 1.945
THBD thrombomodulin 1.944
IL31 interleukin 31 1.943
CD69 CD69 molecule 1.941
ICOS inducible T-cell co-stimulator 1.94
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.937
DCN decorin 1.932
TPO thyroid peroxidase 1.93
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.93
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.926
SAE1 SUMO1 activating enzyme subunit 1 1.926
CCR7 chemokine (C-C motif) receptor 7 1.924
MAPK3 mitogen-activated protein kinase 3 1.923
MRC1 mannose receptor, C type 1 1.922
KDR kinase insert domain receptor 1.922
IFI44L interferon-induced protein 44-like 1.916
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.915
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.912
IL4R interleukin 4 receptor 1.91
CD38 CD38 molecule 1.91
TARS3 threonyl-tRNA synthetase 3 1.91
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.909
SELL selectin L 1.908
IRF8 interferon regulatory factor 8 1.906
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.905
FASLG Fas ligand (TNF superfamily, member 6) 1.905
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.901
IL23R interleukin 23 receptor 1.897
PDGFB platelet-derived growth factor beta polypeptide 1.895
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.894
COMP cartilage oligomeric matrix protein 1.893
HP haptoglobin 1.891
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.888
OSM oncostatin M 1.886
PRF1 perforin 1 (pore forming protein) 1.886
IL2RA interleukin 2 receptor, alpha 1.886
CD274 CD274 molecule 1.885
TG thyroglobulin 1.883
MMP7 matrix metallopeptidase 7 1.883
IL7R interleukin 7 receptor 1.881
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.88
IFNA17 interferon, alpha 17 1.871
CD44 CD44 molecule (Indian blood group) 1.869
NOX4 NADPH oxidase 4 1.866
RPP25 ribonuclease P/MRP 25kDa subunit 1.866
NOS3 nitric oxide synthase 3 (endothelial cell) 1.863
TNPO3 transportin 3 1.862
NLRC4 NLR family, CARD domain containing 4 1.861
SP100 SP100 nuclear antigen 1.861
TARS1 threonyl-tRNA synthetase 1 1.861
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.856
IDO1 indoleamine 2,3-dioxygenase 1 1.856
TP53 tumor protein p53 1.853
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.852
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1.851
LOX lysyl oxidase 1.851
PTX3 pentraxin 3, long 1.85
GATA3 GATA binding protein 3 1.846
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.845
LGALS3 lectin, galactoside-binding, soluble, 3 1.843
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.842
F2 coagulation factor II (thrombin) 1.839
PCNA proliferating cell nuclear antigen 1.837
HMGB1 high mobility group box 1 1.835
CCL20 chemokine (C-C motif) ligand 20 1.834
RHOA ras homolog family member A 1.833
IGF1 insulin-like growth factor 1 (somatomedin C) 1.832
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.829
IL17RA interleukin 17 receptor A 1.824
IL11 interleukin 11 1.822
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.822
HLA-A major histocompatibility complex, class I, A 1.82
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.818
CD247 CD247 molecule 1.814
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.811
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.811
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.811
WRN Werner syndrome, RecQ helicase-like 1.81
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.81
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.809
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.809
NCAM1 neural cell adhesion molecule 1 1.808
CCL11 chemokine (C-C motif) ligand 11 1.806
RPP38 ribonuclease P/MRP 38kDa subunit 1.806
IFNA4 interferon, alpha 4 1.806
FAS Fas cell surface death receptor 1.804
ADIPOQ adiponectin, C1Q and collagen domain containing 1.801
CAMP cathelicidin antimicrobial peptide 1.799
IRF3 interferon regulatory factor 3 1.797
JAK3 Janus kinase 3 1.796
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.793
NT5E 5'-nucleotidase, ecto (CD73) 1.792
BCL2 B-cell CLL/lymphoma 2 1.791
SFTPC surfactant protein C 1.79
IFNA8 interferon, alpha 8 1.786
IFNA6 interferon, alpha 6 1.785
IFNA10 interferon, alpha 10 1.784
IFNA7 interferon, alpha 7 1.783
IFNA21 interferon, alpha 21 1.78
IFNA5 interferon, alpha 5 1.78
IFNA13 interferon, alpha 13 1.779
IFNA14 interferon, alpha 14 1.778
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.777
IFNA16 interferon, alpha 16 1.777
CCL21 chemokine (C-C motif) ligand 21 1.776
AARS1 alanyl-tRNA synthetase 1 1.774
AGBL2 ATP/GTP binding protein-like 2 1.771
AIRE autoimmune regulator 1.771
IL1RN interleukin 1 receptor antagonist 1.771
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.769
STAT5B signal transducer and activator of transcription 5B 1.767
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.765
IFNK interferon, kappa 1.763
CD1D CD1d molecule 1.762
CCL17 chemokine (C-C motif) ligand 17 1.761
IL33R interleukin 33 receptor 1.758
AARS2 alanyl-tRNA synthetase 2, mitochondrial 1.757
CSF1 colony stimulating factor 1 (macrophage) 1.757
CCL19 chemokine (C-C motif) ligand 19 1.755
C4A complement component 4A (Rodgers blood group) 1.755
IRF4 interferon regulatory factor 4 1.755
ACE2 angiotensin I converting enzyme 2 1.749
MYH14 myosin, heavy chain 14, non-muscle 1.747
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.744
IL3 interleukin 3 1.741
GDF15 growth differentiation factor 15 1.74
CD276 CD276 molecule 1.739
STAT5A signal transducer and activator of transcription 5A 1.737
HLA-C major histocompatibility complex, class I, C 1.737
PDCD1 programmed cell death 1 1.735
COL17A1 collagen, type XVII, alpha 1 1.733
IL13RA1 interleukin 13 receptor, alpha 1 1.728
TIMP2 TIMP metallopeptidase inhibitor 2 1.726
FLT1 fms-related tyrosine kinase 1 1.724
ELANE elastase, neutrophil expressed 1.723
SYK spleen tyrosine kinase 1.723
ENO1 enolase 1, (alpha) 1.722
LEP leptin 1.721
CD1C CD1c molecule 1.721
CGAS cyclic GMP-AMP synthase 1.721
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.718
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.713
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.711
IL12RB2 interleukin 12 receptor, beta 2 1.711
PTH parathyroid hormone 1.711
EGFR epidermal growth factor receptor 1.71
GDF2 growth differentiation factor 2 1.71
WDR11 WD repeat domain 11 1.706
CCL7 chemokine (C-C motif) ligand 7 1.706
CHD3 chromodomain helicase DNA binding protein 3 1.705
SNAI1 snail family zinc finger 1 1.703
CD5 CD5 molecule 1.703
FOS FBJ murine osteosarcoma viral oncogene homolog 1.702
RSAD2 radical S-adenosyl methionine domain containing 2 1.702
ACTA2 actin, alpha 2, smooth muscle, aorta 1.701
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.7
IFI16 interferon, gamma-inducible protein 16 1.699
CD226 CD226 molecule 1.699
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 1.698
SDC1 syndecan 1 1.698
CXCL5 chemokine (C-X-C motif) ligand 5 1.696
RETNLB resistin like beta 1.694
PXK PX domain containing serine/threonine kinase 1.693
FGF13 fibroblast growth factor 13 1.692
LOC102723996 ICOS ligand 1.692
IRF1 interferon regulatory factor 1 1.69
NLRP1 NLR family, pyrin domain containing 1 1.688
RUVBL1 RuvB-like AAA ATPase 1 1.688
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.686
TRIM24 tripartite motif containing 24 1.686
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.685
KLRB1 killer cell lectin-like receptor subfamily B, member 1 1.684
ADAM17 ADAM metallopeptidase domain 17 1.682
COL5A2 collagen, type V, alpha 2 1.68
LYN LYN proto-oncogene, Src family tyrosine kinase 1.679
TAC1 tachykinin, precursor 1 1.679
LOXL2 lysyl oxidase-like 2 1.679
ACVRL1 activin A receptor type II-like 1 1.677
PADI4 peptidyl arginine deiminase, type IV 1.675
MMP13 matrix metallopeptidase 13 1.673
IFI27 interferon, alpha-inducible protein 27 1.673
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.673
FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.672
CXCL2 chemokine (C-X-C motif) ligand 2 1.671
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.67
CD70 CD70 molecule 1.67
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.668
CLEC4C C-type lectin domain family 4, member C 1.667
B2M beta-2-microglobulin 1.667
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.667
SIRT1 sirtuin 1 1.667
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.666
DSG3 desmoglein 3 1.665
BTK Bruton agammaglobulinemia tyrosine kinase 1.665
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.663
CCL24 chemokine (C-C motif) ligand 24 1.663
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.662
CD22 CD22 molecule 1.662
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.662
ARG1 arginase 1 1.661
BCR breakpoint cluster region 1.661
SOCS1 suppressor of cytokine signaling 1 1.653
EGR1 early growth response 1 1.65
MCAM melanoma cell adhesion molecule 1.647
ANGPT2 angiopoietin 2 1.647
TEK TEK tyrosine kinase, endothelial 1.647
LTA lymphotoxin alpha 1.646
BGN biglycan 1.646
IL26 interleukin 26 1.644
CTSS cathepsin S 1.644
ACKR2 atypical chemokine receptor 2 1.643
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.642
IDO2 indoleamine 2,3-dioxygenase 2 1.641
SELPLG selectin P ligand 1.638
ADAM12 ADAM metallopeptidase domain 12 1.637
HMOX1 heme oxygenase 1 1.636
TGM2 transglutaminase 2 1.636
DLAT dihydrolipoamide S-acetyltransferase 1.636
KCNK3 potassium channel, two pore domain subfamily K, member 3 1.635
RXFP1 relaxin/insulin-like family peptide receptor 1 1.635
AIM2 absent in melanoma 2 1.635
CCL22 chemokine (C-C motif) ligand 22 1.634
TLR5 toll-like receptor 5 1.634
CCR3 chemokine (C-C motif) receptor 3 1.634
IL21R interleukin 21 receptor 1.633
ISG15 ISG15 ubiquitin-like modifier 1.632
SOCS3 suppressor of cytokine signaling 3 1.632
CHD4 chromodomain helicase DNA binding protein 4 1.631
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.63
PLAU plasminogen activator, urokinase 1.629
STAT2 signal transducer and activator of transcription 2, 113kDa 1.629
ANXA5 annexin A5 1.627
RORC RAR-related orphan receptor C 1.626
OCA2 oculocutaneous albinism II 1.625
CCR1 chemokine (C-C motif) receptor 1 1.625
LMNA lamin A/C 1.622
ITGAV integrin, alpha V 1.619
HLA-G major histocompatibility complex, class I, G 1.619
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.618
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.617
SCARB1 scavenger receptor class B, member 1 1.617
SMAD6 SMAD family member 6 1.615
IFNL1 interferon, lambda 1 1.615
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 1.61
HDAC9 histone deacetylase 9 1.608
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.607
EP300 E1A binding protein p300 1.607
VTN vitronectin 1.605
DSG1 desmoglein 1 1.605
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 1.605
IGFBP5 insulin-like growth factor binding protein 5 1.604
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.603
H2BC21 H2B clustered histone 21 1.602
FLG2 filaggrin family member 2 1.601
FLG filaggrin 1.601
H3C12 H3 clustered histone 12 1.601
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.6
SFRP4 secreted frizzled-related protein 4 1.598
TOR1A torsin family 1, member A (torsin A) 1.597
SCARB2 scavenger receptor class B, member 2 1.597
CYBB cytochrome b-245, beta polypeptide 1.596
ANGPT1 angiopoietin 1 1.596
TSHR thyroid stimulating hormone receptor 1.595
BMP7 bone morphogenetic protein 7 1.595
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.593
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.593
AGER advanced glycosylation end product-specific receptor 1.592
AHR aryl hydrocarbon receptor 1.592
MMP8 matrix metallopeptidase 8 1.592
CD36 CD36 molecule (thrombospondin receptor) 1.592
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.591
H3C13 H3 clustered histone 13 1.591
LCK LCK proto-oncogene, Src family tyrosine kinase 1.59
LPAR3 lysophosphatidic acid receptor 3 1.589
H3-5 H3.5 histone 1.589
H3-4 H3.4 histone, cluster member 1.589
CTSG cathepsin G 1.586
IL3RA interleukin 3 receptor, alpha (low affinity) 1.586
SFTPA2 surfactant protein A2 1.586
IFNE interferon, epsilon 1.585
NOD2 nucleotide-binding oligomerization domain containing 2 1.585
BCL6 B-cell CLL/lymphoma 6 1.584
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.584
PDE4A phosphodiesterase 4A, cAMP-specific 1.584
IL1RAP interleukin 1 receptor accessory protein 1.582
OSMR oncostatin M receptor 1.581
PTEN phosphatase and tensin homolog 1.581
CCN3 cellular communication network factor 3 1.581
H3-3B H3.3 histone B 1.581
SMAD9 SMAD family member 9 1.58
PDGFA platelet-derived growth factor alpha polypeptide 1.579
XYLT1 xylosyltransferase I 1.578
S100A7 S100 calcium binding protein A7 1.578
APOE apolipoprotein E 1.575
CMA1 chymase 1, mast cell 1.575
WNT10B wingless-type MMTV integration site family, member 10B 1.574
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.574
POMC proopiomelanocortin 1.574
ACKR4 atypical chemokine receptor 4 1.573
ESR1 estrogen receptor 1 1.573
CTSK cathepsin K 1.572
TBX4 T-box 4 1.572
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.57
F2R coagulation factor II (thrombin) receptor 1.57
PRSS23 protease, serine, 23 1.569
COL5A1 collagen, type V, alpha 1 1.567
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.567
SPI1 Spi-1 proto-oncogene 1.567
IL25 interleukin 25 1.565
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.565
IRAK4 interleukin-1 receptor-associated kinase 4 1.564
IL12RB1 interleukin 12 receptor, beta 1 1.564
DPP4 dipeptidyl-peptidase 4 1.563
CD46 CD46 molecule, complement regulatory protein 1.561
MFAP5 microfibrillar associated protein 5 1.56
HLA-DRA major histocompatibility complex, class II, DR alpha 1.559
PRL prolactin 1.558
MSR1 macrophage scavenger receptor 1 1.557
VCAN versican 1.556
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.555
TOLLIP toll interacting protein 1.555
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.554
AGBL3 ATP/GTP binding protein-like 3 1.551
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.551
TERT telomerase reverse transcriptase 1.549
ACAN aggrecan 1.548
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.548
CCL8 chemokine (C-C motif) ligand 8 1.548
IARS1 isoleucyl-tRNA synthetase 1 1.548
DST dystonin 1.544
KNG1 kininogen 1 1.544
IL16 interleukin 16 1.544
IL32 interleukin 32 1.543
BPIFA2 BPI fold containing family A, member 2 1.543
S100A9 S100 calcium binding protein A9 1.542
NOS2 nitric oxide synthase 2, inducible 1.541
GREM1 gremlin 1, DAN family BMP antagonist 1.541
CCR10 chemokine (C-C motif) receptor 10 1.54
ICOSLG inducible T-cell co-stimulator ligand 1.54
CHIT1 chitinase 1 (chitotriosidase) 1.538
LPAR6 lysophosphatidic acid receptor 6 1.538
TSPAN4 tetraspanin 4 1.538
RETN resistin 1.536
IRF9 interferon regulatory factor 9 1.535
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.534
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.534
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.532
NOTCH4 notch 4 1.532
CD52 CD52 molecule 1.532
IL23A interleukin 23, alpha subunit p19 1.531
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.531
LTBP1 latent transforming growth factor beta binding protein 1 1.531
DNAL1 dynein, axonemal, light chain 1 1.529
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.529
MOG myelin oligodendrocyte glycoprotein 1.526
CCL13 chemokine (C-C motif) ligand 13 1.526
IL13RA2 interleukin 13 receptor, alpha 2 1.525
TBK1 TANK-binding kinase 1 1.525
ACTA1 actin, alpha 1, skeletal muscle 1.525
IL6ST interleukin 6 signal transducer 1.523
PLAUR plasminogen activator, urokinase receptor 1.523
LTF lactotransferrin 1.523
NGF nerve growth factor (beta polypeptide) 1.522
IL31RA interleukin 31 receptor A 1.522
RAG2 recombination activating gene 2 1.522
CCN1 cellular communication network factor 1 1.521
CD83 CD83 molecule 1.52
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.52
TLR1 toll-like receptor 1 1.519
EPO erythropoietin 1.518
CXCR2 chemokine (C-X-C motif) receptor 2 1.517
MAVS mitochondrial antiviral signaling protein 1.517
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.517
RTEL1 regulator of telomere elongation helicase 1 1.516
PGF placental growth factor 1.514
GSK3B glycogen synthase kinase 3 beta 1.513
CFH complement factor H 1.512
ADCY4 adenylate cyclase 4 1.512
NELFCD negative elongation factor complex member C/D 1.512
ZMPSTE24 zinc metallopeptidase STE24 1.51
IL1F10 interleukin 1 family, member 10 (theta) 1.51
MLN motilin 1.51
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.508
SFRP1 secreted frizzled-related protein 1 1.507
TREX1 three prime repair exonuclease 1 1.507
SNRPC small nuclear ribonucleoprotein polypeptide C 1.507
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.506
CD24 CD24 molecule 1.504
CCN4 cellular communication network factor 4 1.503
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 1.501
LEMD3 LEM domain containing 3 1.5
ATP8B4 ATPase, class I, type 8B, member 4 1.5
COL4A1 collagen, type IV, alpha 1 1.5
C4B complement component 4B (Chido blood group) 1.498
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.498
MYOCD myocardin 1.497
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.496
IL37 interleukin 37 1.494
CREB1 cAMP responsive element binding protein 1 1.493
GSDMA gasdermin A 1.492
NOX1 NADPH oxidase 1 1.492
BMP2 bone morphogenetic protein 2 1.492
CTHRC1 collagen triple helix repeat containing 1 1.492
CSF1R colony stimulating factor 1 receptor 1.491
HSPG2 heparan sulfate proteoglycan 2 1.491
NRP1 neuropilin 1 1.49
VIP vasoactive intestinal peptide 1.49
CSK c-src tyrosine kinase 1.489
JAG1 jagged 1 1.487
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.482
TPH1 tryptophan hydroxylase 1 1.481
PLAT plasminogen activator, tissue 1.476
AREG amphiregulin 1.475
WIF1 WNT inhibitory factor 1 1.474
TGFA transforming growth factor, alpha 1.474
PARN poly(A)-specific ribonuclease 1.474
TSSK2 testis-specific serine kinase 2 1.473
TAGLN transgelin 1.471
BMP4 bone morphogenetic protein 4 1.471
IFNGR1 interferon gamma receptor 1 1.471
IFI6 interferon, alpha-inducible protein 6 1.47
KITLG KIT ligand 1.47
NPPA natriuretic peptide A 1.469
PRDM1 PR domain containing 1, with ZNF domain 1.469
MUSK muscle, skeletal, receptor tyrosine kinase 1.466
MME membrane metallo-endopeptidase 1.465
SIRT3 sirtuin 3 1.465
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.464
CXCL16 chemokine (C-X-C motif) ligand 16 1.464
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.463
GLB1 galactosidase, beta 1 1.462
LPAR2 lysophosphatidic acid receptor 2 1.462
MBP myelin basic protein 1.461
AGTR2 angiotensin II receptor, type 2 1.458
CD1E CD1e molecule 1.457
THBS2 thrombospondin 2 1.457
KLF4 Kruppel-like factor 4 (gut) 1.455
CD1B CD1b molecule 1.453
H2AC18 H2A clustered histone 18 1.453
H2AC20 H2A clustered histone 20 1.45
HDAC1 histone deacetylase 1 1.447
CCL23 chemokine (C-C motif) ligand 23 1.445
HBEGF heparin-binding EGF-like growth factor 1.445
PTK2 protein tyrosine kinase 2 1.445
LY6E lymphocyte antigen 6 complex, locus E 1.445
LPAR4 lysophosphatidic acid receptor 4 1.444
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.444
S100A12 S100 calcium binding protein A12 1.443
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.441
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.44
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.439
CD9 CD9 molecule 1.437
RAG1 recombination activating gene 1 1.436
FOXO3 forkhead box O3 1.435
VCL vinculin 1.434
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.433
CD1A CD1a molecule 1.433
CCND1 cyclin D1 1.433
IL18R1 interleukin 18 receptor 1 1.432
APLN apelin 1.432
MAPK8 mitogen-activated protein kinase 8 1.431
PF4V1 platelet factor 4 variant 1 1.43
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.43
LPAR5 lysophosphatidic acid receptor 5 1.429
IL2RB interleukin 2 receptor, beta 1.429
SHH sonic hedgehog 1.429
MMP10 matrix metallopeptidase 10 1.428
TGFBR3 transforming growth factor, beta receptor III 1.428
NOTCH1 notch 1 1.427
SNAI2 snail family zinc finger 2 1.427
HSPA4 heat shock 70kDa protein 4 1.427
WNT5A wingless-type MMTV integration site family, member 5A 1.426
TIMP3 TIMP metallopeptidase inhibitor 3 1.425
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.425
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.425
GLI1 GLI family zinc finger 1 1.425
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.424
VEGFC vascular endothelial growth factor C 1.423
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.422
CDKN2A cyclin-dependent kinase inhibitor 2A 1.422
BCL2L1 BCL2-like 1 1.418
CD2 CD2 molecule 1.418
SFRP2 secreted frizzled-related protein 2 1.417
ERVW-1 endogenous retrovirus group W, member 1 1.416
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.414
PROM1 prominin 1 1.414
GSDMD gasdermin D 1.411
AIF1 allograft inflammatory factor 1 1.411
MECP2 methyl CpG binding protein 2 1.41
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.41
LCN2 lipocalin 2 1.409
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.408
ANPEP alanyl (membrane) aminopeptidase 1.408
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.407
SNRPA small nuclear ribonucleoprotein polypeptide A 1.407
IFNL2 interferon, lambda 2 1.407
BAX BCL2-associated X protein 1.406
PDCD1LG2 programmed cell death 1 ligand 2 1.405
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.405
LGALS9 lectin, galactoside-binding, soluble, 9 1.405
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.402
FSTL1 follistatin-like 1 1.4
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.4
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.399
ADA adenosine deaminase 1.399
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.397
CCL27 chemokine (C-C motif) ligand 27 1.397
HAVCR2 hepatitis A virus cellular receptor 2 1.397
PTGDR2 prostaglandin D2 receptor 2 1.396
APOA1 apolipoprotein A-I 1.395
LUM lumican 1.395
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 1.395
ATG5 autophagy related 5 1.395
ICAM2 intercellular adhesion molecule 2 1.394
IL24 interleukin 24 1.392
RUNX2 runt-related transcription factor 2 1.392
USP18 ubiquitin specific peptidase 18 1.391
EDN3 endothelin 3 1.391
PRKCD protein kinase C, delta 1.389
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 1.388
TRAT1 T cell receptor associated transmembrane adaptor 1 1.388
COL8A1 collagen, type VIII, alpha 1 1.386
PPARA peroxisome proliferator-activated receptor alpha 1.386
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 1.386
CD59 CD59 molecule, complement regulatory protein 1.385
COIL coilin 1.384
CD63 CD63 molecule 1.382
EDA ectodysplasin A 1.381
NAMPT nicotinamide phosphoribosyltransferase 1.381
DGKE diacylglycerol kinase, epsilon 64kDa 1.38
LGALS9C lectin, galactoside-binding, soluble, 9C 1.379
DNAH8 dynein, axonemal, heavy chain 8 1.379
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 1.379
EDN2 endothelin 2 1.377
SMAD5 SMAD family member 5 1.376
CA6 carbonic anhydrase VI 1.376
B3GAT1 beta-1,3-glucuronyltransferase 1 1.374
IL19 interleukin 19 1.373
ARG2 arginase 2 1.372
LAG3 lymphocyte-activation gene 3 1.371
BGLAP bone gamma-carboxyglutamate (gla) protein 1.371
S1PR1 sphingosine-1-phosphate receptor 1 1.37
STING1 stimulator of interferon response cGAMP interactor 1 1.369
FLT4 fms-related tyrosine kinase 4 1.368
ERV3-1 endogenous retrovirus group 3, member 1 1.368
ECM1 extracellular matrix protein 1 1.367
TFRC transferrin receptor 1.365
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.363
CD81 CD81 molecule 1.363
IL1R2 interleukin 1 receptor, type II 1.363
LBR lamin B receptor 1.362
MB myoglobin 1.361
MRTFA myocardin related transcription factor A 1.361
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.36
IL17C interleukin 17C 1.36
CISH cytokine inducible SH2-containing protein 1.359
ANXA2 annexin A2 1.359
TTR transthyretin 1.359
NVL nuclear VCP-like 1.358
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.357
IL17B interleukin 17B 1.356
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.356
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.356
ADAM10 ADAM metallopeptidase domain 10 1.355
CD180 CD180 molecule 1.355
FOXO1 forkhead box O1 1.354
LGALS9B lectin, galactoside-binding, soluble, 9B 1.353
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 1.353
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.352
NFE2L2 nuclear factor, erythroid 2-like 2 1.351
CST3 cystatin C 1.35
ADM adrenomedullin 1.349
RUNX1 runt-related transcription factor 1 1.349
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.348
SOD2 superoxide dismutase 2, mitochondrial 1.348
FGF1 fibroblast growth factor 1 (acidic) 1.347
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.347
WNT1 wingless-type MMTV integration site family, member 1 1.346
MEFV Mediterranean fever 1.346
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.345
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.344
PLD3 phospholipase D family, member 3 1.344
PADI2 peptidyl arginine deiminase, type II 1.344
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.344
EPAS1 endothelial PAS domain protein 1 1.344
AICDA activation-induced cytidine deaminase 1.343
PTGIS prostaglandin I2 (prostacyclin) synthase 1.341
KLF5 Kruppel-like factor 5 (intestinal) 1.34
RLN2 relaxin 2 1.34
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.339
MBL2 mannose-binding lectin (protein C) 2, soluble 1.338
LY96 lymphocyte antigen 96 1.336
RPP40 ribonuclease P/MRP 40kDa subunit 1.336
CXCR6 chemokine (C-X-C motif) receptor 6 1.336
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.336
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.336
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.335
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.335
THPO thrombopoietin 1.335
NOTCH3 notch 3 1.334
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.333
PI3 peptidase inhibitor 3, skin-derived 1.332
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.332
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 1.332
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.331
COL12A1 collagen, type XII, alpha 1 1.331
APCS amyloid P component, serum 1.331
LIF leukemia inhibitory factor 1.329
IL2RG interleukin 2 receptor, gamma 1.329
RUNX3 runt-related transcription factor 3 1.329
ERBB2 erb-b2 receptor tyrosine kinase 2 1.328
FCN1 ficolin (collagen/fibrinogen domain containing) 1 1.327
TGFBI transforming growth factor, beta-induced, 68kDa 1.326
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.325
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.325
GSDMB gasdermin B 1.324
LOXL1 lysyl oxidase-like 1 1.324
CALR calreticulin 1.323
PDPN podoplanin 1.323
C5AR1 complement component 5a receptor 1 1.323
CXCR1 chemokine (C-X-C motif) receptor 1 1.322
ATP13A3 ATPase type 13A3 1.322
NID1 nidogen 1 1.32
CCL26 chemokine (C-C motif) ligand 26 1.32
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.319
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 1.319
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 1.319
SPON1 spondin 1, extracellular matrix protein 1.318
VEGFD vascular endothelial growth factor D 1.318
CLEC16A C-type lectin domain family 16, member A 1.317
BIRC5 baculoviral IAP repeat containing 5 1.317
HOXD13 homeobox D13 1.316
CD47 CD47 molecule 1.316
ZEB1 zinc finger E-box binding homeobox 1 1.315
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.315
CDC42 cell division cycle 42 1.315
TTN titin 1.315
TLR6 toll-like receptor 6 1.315
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.314
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 1.313
GLI2 GLI family zinc finger 2 1.311
SH2B3 SH2B adaptor protein 3 1.311
VGLL3 vestigial-like family member 3 1.311
SAMHD1 SAM domain and HD domain 1 1.31
C5 complement component 5 1.307
FCAR Fc fragment of IgA receptor 1.306
ATF3 activating transcription factor 3 1.306
IGFBP3 insulin-like growth factor binding protein 3 1.305
IFNLR1 interferon, lambda receptor 1 1.305
CD72 CD72 molecule 1.305
MLNR motilin receptor 1.304
IL34 interleukin 34 1.303
CFD complement factor D (adipsin) 1.302
KDM6B lysine (K)-specific demethylase 6B 1.302
WNT3A wingless-type MMTV integration site family, member 3A 1.302
IFITM1 interferon induced transmembrane protein 1 1.302
SAA1 serum amyloid A1 1.302
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.301
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.3
HDAC2 histone deacetylase 2 1.299
IL18BP interleukin 18 binding protein 1.297
FPR2 formyl peptide receptor 2 1.297
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.296
S100A6 S100 calcium binding protein A6 1.296
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.296
TBL1X transducin (beta)-like 1X-linked 1.295
CFB complement factor B 1.292
IL17RC interleukin 17 receptor C 1.292
FABP4 fatty acid binding protein 4, adipocyte 1.291
DICER1 dicer 1, ribonuclease type III 1.287
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.286
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.286
KL klotho 1.286
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.285
TWIST1 twist family bHLH transcription factor 1 1.285
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.285
NOTCH2 notch 2 1.283
DEFB4A defensin, beta 4A 1.283
FBN2 fibrillin 2 1.282
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 1.282
GPX3 glutathione peroxidase 3 1.282
S100A8 S100 calcium binding protein A8 1.281
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 1.28
IL21 interleukin 21 1.279
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.278
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.277
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.277
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.277
MMP28 matrix metallopeptidase 28 1.276
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.276
CD79A CD79a molecule, immunoglobulin-associated alpha 1.274
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.273
FPR1 formyl peptide receptor 1 1.273
ESM1 endothelial cell-specific molecule 1 1.273
KAT2B K(lysine) acetyltransferase 2B 1.272
CXCL3 chemokine (C-X-C motif) ligand 3 1.27
ADAR adenosine deaminase, RNA-specific 1.27
FAM13A family with sequence similarity 13, member A 1.27
SST somatostatin 1.269
TNNI3 troponin I type 3 (cardiac) 1.269
CD93 CD93 molecule 1.269
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.268
BRD4 bromodomain containing 4 1.267
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 1.266
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.266
COL11A1 collagen, type XI, alpha 1 1.264
KRT14 keratin 14, type I 1.263
FBLN5 fibulin 5 1.262
CCL1 chemokine (C-C motif) ligand 1 1.262
SAA2 serum amyloid A2 1.262
EOMES eomesodermin 1.261
KLF2 Kruppel-like factor 2 1.261
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.26
CYCS cytochrome c, somatic 1.26
ARRB2 arrestin, beta 2 1.259
LTBP4 latent transforming growth factor beta binding protein 4 1.259
CHUK conserved helix-loop-helix ubiquitous kinase 1.258
APLNR apelin receptor 1.257
GP1BA glycoprotein Ib (platelet), alpha polypeptide 1.256
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.256
TXN thioredoxin 1.255
TNNT2 troponin T type 2 (cardiac) 1.255
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 1.254
SCHIP1 schwannomin interacting protein 1 1.254
TRAF3 TNF receptor-associated factor 3 1.253
TRAF1 TNF receptor-associated factor 1 1.251
HAS2 hyaluronan synthase 2 1.251
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.25
MAPK1 mitogen-activated protein kinase 1 1.249
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.249
HSPB3 heat shock 27kDa protein 3 1.248
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.248
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.248
WNT2 wingless-type MMTV integration site family member 2 1.246
PDGFC platelet derived growth factor C 1.246
OASL 2'-5'-oligoadenylate synthetase-like 1.245
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.244
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.244
LOXL4 lysyl oxidase-like 4 1.243
COL4A2 collagen, type IV, alpha 2 1.243
CFHR1 complement factor H-related 1 1.243
SDC4 syndecan 4 1.242
COL10A1 collagen, type X, alpha 1 1.242
MAP2K1 mitogen-activated protein kinase kinase 1 1.241
TMEM11 transmembrane protein 11 1.241
IL10RB interleukin 10 receptor, beta 1.24
FGFR1 fibroblast growth factor receptor 1 1.24
MSN moesin 1.24
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.24
IL22RA1 interleukin 22 receptor, alpha 1 1.238
ILK integrin-linked kinase 1.238
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.237
MERTK MER proto-oncogene, tyrosine kinase 1.237
GRB2 growth factor receptor-bound protein 2 1.237
HLA-E major histocompatibility complex, class I, E 1.236
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.236
THBS4 thrombospondin 4 1.236
SFTPA1 surfactant protein A1 1.236
TET2 tet methylcytosine dioxygenase 2 1.235
CP ceruloplasmin (ferroxidase) 1.235
ZNRD2 zinc ribbon domain containing 2 1.235
CFHR3 complement factor H-related 3 1.233
IGF2 insulin-like growth factor 2 1.231
AOC3 amine oxidase, copper containing 3 1.231
CHIA chitinase, acidic 1.231
CA2 carbonic anhydrase II 1.231
HNF4A hepatocyte nuclear factor 4, alpha 1.231
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.23
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.229
TIGIT T cell immunoreceptor with Ig and ITIM domains 1.228
IL36RN interleukin 36 receptor antagonist 1.228
CCK cholecystokinin 1.226
AGO2 argonaute RISC catalytic component 2 1.225
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.225
GRN granulin 1.224
BMP1 bone morphogenetic protein 1 1.224
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.224
XDH xanthine dehydrogenase 1.224
COL6A3 collagen, type VI, alpha 3 1.22
GCG glucagon 1.22
ATM ATM serine/threonine kinase 1.219
PDZK1IP1 PDZK1 interacting protein 1 1.218
DROSHA drosha, ribonuclease type III 1.217
MSTN myostatin 1.217
XYLT2 xylosyltransferase II 1.217
SLAMF1 signaling lymphocytic activation molecule family member 1 1.217
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.216
RNASEH2B ribonuclease H2, subunit B 1.215
TLR10 toll-like receptor 10 1.215
LDLR low density lipoprotein receptor 1.215
FYN FYN proto-oncogene, Src family tyrosine kinase 1.215
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.215
CD58 CD58 molecule 1.214
BTNL2 butyrophilin-like 2 1.214
HDAC4 histone deacetylase 4 1.214
BATF basic leucine zipper transcription factor, ATF-like 1.214
RNASE3 ribonuclease, RNase A family, 3 1.213
C1S complement component 1, s subcomponent 1.213
CCR8 chemokine (C-C motif) receptor 8 1.213
DLL4 delta-like 4 (Drosophila) 1.212
TJP1 tight junction protein 1 1.212
COL23A1 collagen, type XXIII, alpha 1 1.212
MAPK14 mitogen-activated protein kinase 14 1.211
JUND jun D proto-oncogene 1.211
GPX2 glutathione peroxidase 2 1.211
FRZB frizzled-related protein 1.21
FGF23 fibroblast growth factor 23 1.21
IL10RA interleukin 10 receptor, alpha 1.209
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.209
TET1 tet methylcytosine dioxygenase 1 1.209
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.208
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.208
C1R complement component 1, r subcomponent 1.208
GPX7 glutathione peroxidase 7 1.208
CTSB cathepsin B 1.207
DPT dermatopontin 1.207
A2M alpha-2-macroglobulin 1.207
GPX8 glutathione peroxidase 8 (putative) 1.207
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.206
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.206
TPMT thiopurine S-methyltransferase 1.206
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 1.205
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.205
GZMK granzyme K (granzyme 3; tryptase II) 1.204
ERAP1 endoplasmic reticulum aminopeptidase 1 1.203
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.203
GPX5 glutathione peroxidase 5 1.203
IL17D interleukin 17D 1.202
SPHK1 sphingosine kinase 1 1.201
NKG7 natural killer cell granule protein 7 1.201
CD209 CD209 molecule 1.2
IL17RB interleukin 17 receptor B 1.2
IGF1R insulin-like growth factor 1 receptor 1.2
GPX6 glutathione peroxidase 6 1.2
ASPN asporin 1.199
PI16 peptidase inhibitor 16 1.199
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 1.198
SNRPN small nuclear ribonucleoprotein polypeptide N 1.198
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 1.197
PLCL1 phospholipase C-like 1 1.196
KRT5 keratin 5, type II 1.196
IFNL3 interferon, lambda 3 1.196
FURIN furin (paired basic amino acid cleaving enzyme) 1.195
LRP5 low density lipoprotein receptor-related protein 5 1.194
MYOM2 myomesin 2 1.194
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.194
HAMP hepcidin antimicrobial peptide 1.192
FSTL3 follistatin-like 3 (secreted glycoprotein) 1.192
ITK IL2-inducible T-cell kinase 1.191
ACVR1 activin A receptor, type I 1.19
AXIN2 axin 2 1.19
ADCY5 adenylate cyclase 5 1.189
IGFBP7 insulin-like growth factor binding protein 7 1.189
UNC93B1 unc-93 homolog B1 (C. elegans) 1.189
C3AR1 complement component 3a receptor 1 1.189
ARNT aryl hydrocarbon receptor nuclear translocator 1.188
ANXA1 annexin A1 1.187
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.187
PTCH1 patched 1 1.185
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.185
PLCL2 phospholipase C-like 2 1.185
IL36R interleukin 36 receptor 1.185
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.185
RNASEH2C ribonuclease H2, subunit C 1.184
COL7A1 collagen, type VII, alpha 1 1.184
CRLF2 cytokine receptor-like factor 2 1.184
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 1.183
RHOB ras homolog family member B 1.183
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 1.182
SOX2 SRY (sex determining region Y)-box 2 1.182
CCN5 cellular communication network factor 5 1.182
AQP5 aquaporin 5 1.181
CALML5 calmodulin-like 5 1.181
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.181
MX2 MX dynamin-like GTPase 2 1.181
GAST gastrin 1.181
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.181
APP amyloid beta (A4) precursor protein 1.18
RPP30 ribonuclease P/MRP 30kDa subunit 1.179
CCR9 chemokine (C-C motif) receptor 9 1.179
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.179
BECN1 beclin 1, autophagy related 1.177
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.177
FMOD fibromodulin 1.176
YAP1 Yes-associated protein 1 1.176
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1.175
COL22A1 collagen, type XXII, alpha 1 1.174
PSD3 pleckstrin and Sec7 domain containing 3 1.174
FLT3 fms-related tyrosine kinase 3 1.173
DNASE2 deoxyribonuclease II, lysosomal 1.172
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.171
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.171
H4C6 H4 clustered histone 6 1.171
PARP1 poly (ADP-ribose) polymerase 1 1.17
CFP complement factor properdin 1.168
CENPF centromere protein F, 350/400kDa 1.168
SUMO1 small ubiquitin-like modifier 1 1.168
IFI35 interferon-induced protein 35 1.167
ARRB1 arrestin, beta 1 1.167
ANKRD55 ankyrin repeat domain 55 1.166
IL9R interleukin 9 receptor 1.166
CD3D CD3d molecule, delta (CD3-TCR complex) 1.165
RUVBL2 RuvB-like AAA ATPase 2 1.165
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.165
CD7 CD7 molecule 1.164
SP1 Sp1 transcription factor 1.163
SLAMF7 SLAM family member 7 1.163
NUMA1 nuclear mitotic apparatus protein 1 1.162
PPARD peroxisome proliferator-activated receptor delta 1.162
SOX9 SRY (sex determining region Y)-box 9 1.162
H4C7 H4 clustered histone 7 1.162
GBP1 guanylate binding protein 1, interferon-inducible 1.161
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.159
SDC2 syndecan 2 1.159
NOS1 nitric oxide synthase 1 (neuronal) 1.157
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.157
CTSL cathepsin L 1.156
SRY sex determining region Y 1.156
KRT1 keratin 1, type II 1.153
KRT15 keratin 15, type I 1.153
CD84 CD84 molecule 1.152
ADCY8 adenylate cyclase 8 (brain) 1.151
BST2 bone marrow stromal cell antigen 2 1.151
CXCL6 chemokine (C-X-C motif) ligand 6 1.15
XBP1 X-box binding protein 1 1.149
HSPA1B heat shock 70kDa protein 1B 1.149
TIMP4 TIMP metallopeptidase inhibitor 4 1.149
BAMBI BMP and activin membrane-bound inhibitor 1.149
PXN paxillin 1.149
INSR insulin receptor 1.148
LEF1 lymphoid enhancer-binding factor 1 1.147
DHFR dihydrofolate reductase 1.147
IRAK3 interleukin-1 receptor-associated kinase 3 1.145
DUSP1 dual specificity phosphatase 1 1.145
KRT10 keratin 10, type I 1.144
DGKQ diacylglycerol kinase, theta 110kDa 1.144
HRH2 histamine receptor H2 1.143
DNASE1 deoxyribonuclease I 1.142
BICD2 bicaudal D homolog 2 (Drosophila) 1.142
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.14
CLU clusterin 1.139
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.138
COL14A1 collagen, type XIV, alpha 1 1.138
TNIP2 TNFAIP3 interacting protein 2 1.138
S1PR5 sphingosine-1-phosphate receptor 5 1.138
EGR2 early growth response 2 1.137
NGFR nerve growth factor receptor 1.137
ATG7 autophagy related 7 1.136
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 1.135
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.134
PLXND1 plexin D1 1.133
EFNB2 ephrin-B2 1.132
COL4A4 collagen, type IV, alpha 4 1.132
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 1.131
SOST sclerostin 1.131
SPN sialophorin 1.131
IVL involucrin 1.131
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.131
F8 coagulation factor VIII, procoagulant component 1.131
IGFBP1 insulin-like growth factor binding protein 1 1.13
COL15A1 collagen, type XV, alpha 1 1.13
ADRB1 adrenoceptor beta 1 1.129
CALML6 calmodulin-like 6 1.128
CALML4 calmodulin-like 4 1.128
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.128
SLPI secretory leukocyte peptidase inhibitor 1.128
FLT3LG fms-related tyrosine kinase 3 ligand 1.128
ZBTB7B zinc finger and BTB domain containing 7B 1.126
CALML3 calmodulin-like 3 1.126
SRSF6 serine/arginine-rich splicing factor 6 1.126
ADAM8 ADAM metallopeptidase domain 8 1.125
NCR2 natural cytotoxicity triggering receptor 2 1.125
COL6A1 collagen, type VI, alpha 1 1.124
SOX17 SRY (sex determining region Y)-box 17 1.124
GPATCH2L G patch domain containing 2-like 1.123
ERN1 endoplasmic reticulum to nucleus signaling 1 1.123
GNLY granulysin 1.123
RXFP4 relaxin/insulin-like family peptide receptor 4 1.123
ANXA11 annexin A11 1.123
BDNF brain-derived neurotrophic factor 1.122
RGCC regulator of cell cycle 1.121
ALK anaplastic lymphoma receptor tyrosine kinase 1.121
ACVR2A activin A receptor, type IIA 1.12
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.12
MET MET proto-oncogene, receptor tyrosine kinase 1.119
NLRP10 NLR family, pyrin domain containing 10 1.119
FBLN1 fibulin 1 1.119
VIM vimentin 1.119
PDHX pyruvate dehydrogenase complex, component X 1.118
CD33 CD33 molecule 1.117
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 1.117
ACP5 acid phosphatase 5, tartrate resistant 1.117
FADD Fas (TNFRSF6)-associated via death domain 1.115
CST4 cystatin S 1.114
MBD4 methyl-CpG binding domain protein 4 1.114
IRGM immunity-related GTPase family, M 1.113
AXIN1 axin 1 1.113
VAV1 vav 1 guanine nucleotide exchange factor 1.112
ECE1 endothelin converting enzyme 1 1.112
MAPK13 mitogen-activated protein kinase 13 1.112
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.112
ZEB2 zinc finger E-box binding homeobox 2 1.112
F11R F11 receptor 1.112
P4HB prolyl 4-hydroxylase, beta polypeptide 1.111
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.111
GBP2 guanylate binding protein 2, interferon-inducible 1.111
SRP54 signal recognition particle 54kDa 1.11
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.11
TNXB tenascin XB 1.109
HDAC3 histone deacetylase 3 1.108
HDAC6 histone deacetylase 6 1.108
CTSD cathepsin D 1.107
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.107
BSG basigin (Ok blood group) 1.107
FMO1 flavin containing monooxygenase 1 1.107
SFTPB surfactant protein B 1.106
GHRL ghrelin/obestatin prepropeptide 1.106
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.106
H1-0 H1.0 linker histone 1.106
ITGB6 integrin, beta 6 1.105
TBRG1 transforming growth factor beta regulator 1 1.105
LOXL3 lysyl oxidase-like 3 1.104
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.104
CFI complement factor I 1.103
SPDL1 spindle apparatus coiled-coil protein 1 1.103
MAPK11 mitogen-activated protein kinase 11 1.103
POTEF POTE ankyrin domain family, member F 1.103
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.103
CD200 CD200 molecule 1.103
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.102
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.102
GREM2 gremlin 2, DAN family BMP antagonist 1.102
ACVR1B activin A receptor, type IB 1.102
BMP6 bone morphogenetic protein 6 1.101
CDK2 cyclin-dependent kinase 2 1.101
PRKG1 protein kinase, cGMP-dependent, type I 1.1
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.1
PHGDH phosphoglycerate dehydrogenase 1.099
EBF1 early B-cell factor 1 1.099
EZR ezrin 1.098
DKC1 dyskeratosis congenita 1, dyskerin 1.098
BPI bactericidal/permeability-increasing protein 1.096
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 1.093
ITGB5 integrin, beta 5 1.092
ATF6 activating transcription factor 6 1.092
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.09
FST follistatin 1.09
EGFL7 EGF-like-domain, multiple 7 1.09
PHRF1 PHD and ring finger domains 1 1.09
PCSK5 proprotein convertase subtilisin/kexin type 5 1.089
LRRC32 leucine rich repeat containing 32 1.089
PDGFD platelet derived growth factor D 1.089
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.089
IL18RAP interleukin 18 receptor accessory protein 1.088
DUOX1 dual oxidase 1 1.088
COL13A1 collagen, type XIII, alpha 1 1.088
ACVR2B activin A receptor, type IIB 1.087
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.087
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.087
SIRPA signal-regulatory protein alpha 1.086
CLEC7A C-type lectin domain family 7, member A 1.086
TYR tyrosinase 1.085
NCF1 neutrophil cytosolic factor 1 1.085
MYB v-myb avian myeloblastosis viral oncogene homolog 1.085
MGP matrix Gla protein 1.084
PLSCR1 phospholipid scramblase 1 1.084
CFL1 cofilin 1 (non-muscle) 1.084
APOB apolipoprotein B 1.083
SOX5 SRY (sex determining region Y)-box 5 1.083
FOSL1 FOS-like antigen 1 1.083
S1PR2 sphingosine-1-phosphate receptor 2 1.083
IL27RA interleukin 27 receptor, alpha 1.083
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.082
COL6A5 collagen, type VI, alpha 5 1.082
INSM2 insulinoma-associated 2 1.082
KLF10 Kruppel-like factor 10 1.082
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.081
FCN3 ficolin (collagen/fibrinogen domain containing) 3 1.08
TRIM45 tripartite motif containing 45 1.08
PAX5 paired box 5 1.08
FKBP1A FK506 binding protein 1A, 12kDa 1.079
NCR3 natural cytotoxicity triggering receptor 3 1.079
PYHIN1 pyrin and HIN domain family, member 1 1.079
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.078
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.078
PTGES prostaglandin E synthase 1.078
PARP9 poly (ADP-ribose) polymerase family, member 9 1.078
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.077
FGR FGR proto-oncogene, Src family tyrosine kinase 1.076
BLNK B-cell linker 1.076
ADORA2A adenosine A2a receptor 1.076
BMP10 bone morphogenetic protein 10 1.076
NOD1 nucleotide-binding oligomerization domain containing 1 1.075
KEAP1 kelch-like ECH-associated protein 1 1.075
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.075
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.075
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 1.074
ALPL alkaline phosphatase, liver/bone/kidney 1.073
AXL AXL receptor tyrosine kinase 1.073
DBT dihydrolipoamide branched chain transacylase E2 1.073
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.073
HSPA1A heat shock 70kDa protein 1A 1.072
JAM3 junctional adhesion molecule 3 1.072
MFAP2 microfibrillar-associated protein 2 1.072
TREM1 triggering receptor expressed on myeloid cells 1 1.072
PTK2B protein tyrosine kinase 2 beta 1.072
DHFR2 dihydrofolate reductase 2 1.072
KRT17 keratin 17, type I 1.07
GJA1 gap junction protein, alpha 1, 43kDa 1.07
ITGA1 integrin, alpha 1 1.069
KRT19 keratin 19, type I 1.069
LAMP1 lysosomal-associated membrane protein 1 1.069
KLRC1 killer cell lectin-like receptor subfamily C, member 1 1.069
NUCLEOLIN nucleolin multifunctional protein 1.069
RNASEH2A ribonuclease H2, subunit A 1.068
CFLAR CASP8 and FADD-like apoptosis regulator 1.068
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.068
CNR2 cannabinoid receptor 2 (macrophage) 1.067
CENPI centromere protein I 1.067
IRAK2 interleukin-1 receptor-associated kinase 2 1.067
CXCL14 chemokine (C-X-C motif) ligand 14 1.067
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.067
OCLN occludin 1.066
KRAS Kirsten rat sarcoma viral oncogene homolog 1.065
CTF1 cardiotrophin 1 1.065
POU5F1 POU class 5 homeobox 1 1.065
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.065
SLIT3 slit homolog 3 (Drosophila) 1.065
COL2A1 collagen, type II, alpha 1 1.065
MMEL1 membrane metallo-endopeptidase-like 1 1.064
SPPL2C signal peptide peptidase like 2C 1.064
HDAC5 histone deacetylase 5 1.063
MPPE1 metallophosphoesterase 1 1.063
SAA4 serum amyloid A4, constitutive 1.063
ITGA9 integrin, alpha 9 1.062
TCF7 transcription factor 7 (T-cell specific, HMG-box) 1.061
MAPK12 mitogen-activated protein kinase 12 1.06
NPY neuropeptide Y 1.06
TRADD TNFRSF1A-associated via death domain 1.058
IGFBP4 insulin-like growth factor binding protein 4 1.058
DMD dystrophin 1.058
DKK2 dickkopf WNT signaling pathway inhibitor 2 1.058
ALCAM activated leukocyte cell adhesion molecule 1.058
DSG2 desmoglein 2 1.058
PLEKHM3 pleckstrin homology domain containing, family M, member 3 1.057
CIITA class II, major histocompatibility complex, transactivator 1.056
SAA2-SAA4 SAA2-SAA4 readthrough 1.056
ADCY9 adenylate cyclase 9 1.055
AGO1 argonaute RISC catalytic component 1 1.055
TANK TRAF family member-associated NFKB activator 1.055
MCL1 myeloid cell leukemia 1 1.054
HRAS Harvey rat sarcoma viral oncogene homolog 1.054
TMPRSS2 transmembrane protease, serine 2 1.053
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.052
ADIPOR1 adiponectin receptor 1 1.052
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 1.052
CBLN2 cerebellin 2 precursor 1.052
MZB1 marginal zone B and B1 cell-specific protein 1.051
NCR1 natural cytotoxicity triggering receptor 1 1.049
LYZ lysozyme 1.049
LGALS7 lectin, galactoside-binding, soluble, 7 1.049
LGALS7B lectin, galactoside-binding, soluble, 7B 1.049
ESR2 estrogen receptor 2 (ER beta) 1.049
BMPR1B bone morphogenetic protein receptor, type IB 1.049
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.048
HDAC7 histone deacetylase 7 1.047
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.046
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.045
ZFYVE9 zinc finger, FYVE domain containing 9 1.045
STAC SH3 and cysteine rich domain 1.044
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 1.043
IRF2 interferon regulatory factor 2 1.043
TOR1B torsin family 1, member B (torsin B) 1.042
TYRP1 tyrosinase-related protein 1 1.042
LTB lymphotoxin beta (TNF superfamily, member 3) 1.042
WDFY4 WDFY family member 4 1.041
AHSG alpha-2-HS-glycoprotein 1.041
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.041
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.041
XPO5 exportin 5 1.039
ENO2 enolase 2 (gamma, neuronal) 1.037
ENHO energy homeostasis associated 1.037
LTB4R leukotriene B4 receptor 1.037
S1PR3 sphingosine-1-phosphate receptor 3 1.037
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.037
TCIM transcriptional and immune response regulator 1.037
DEFA1B defensin, alpha 1B 1.036
EXOC2 exocyst complex component 2 1.036
ZUP1 zinc finger containing ubiquitin peptidase 1 1.036
CCL25 chemokine (C-C motif) ligand 25 1.035
RASAL1 RAS protein activator like 1 (GAP1 like) 1.035
PYCARD PYD and CARD domain containing 1.034
ECE2 endothelin converting enzyme 2 1.034
DDR1 discoidin domain receptor tyrosine kinase 1 1.033
AFP alpha-fetoprotein 1.032
CENPO centromere protein O 1.032
TMSB4X thymosin beta 4, X-linked 1.031
TET3 tet methylcytosine dioxygenase 3 1.031
YY1 YY1 transcription factor 1.031
DSP desmoplakin 1.03
XAF1 XIAP associated factor 1 1.03
CREBBP CREB binding protein 1.029
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.027
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.027
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.027
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.026
DDAH1 dimethylarginine dimethylaminohydrolase 1 1.026
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.025
MICB MHC class I polypeptide-related sequence B 1.025
ADORA2B adenosine A2b receptor 1.023
OTUD6B OTU domain containing 6B 1.022
IFITM3 interferon induced transmembrane protein 3 1.022
ITGB8 integrin, beta 8 1.021
MFGE8 milk fat globule-EGF factor 8 protein 1.021
UBASH3A ubiquitin associated and SH3 domain containing A 1.021
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.02
LRP2 low density lipoprotein receptor-related protein 2 1.02
TYROBP TYRO protein tyrosine kinase binding protein 1.02
PTS 6-pyruvoyltetrahydropterin synthase 1.019
SMAD1 SMAD family member 1 1.018
LGI1 leucine-rich, glioma inactivated 1 1.018
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 1.018
SLIT2 slit homolog 2 (Drosophila) 1.017
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.017
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.015
PLIN1 perilipin 1 1.015
MAG myelin associated glycoprotein 1.015
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.014
ETV2 ets variant 2 1.014
WNT4 wingless-type MMTV integration site family, member 4 1.013
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.013
TRIB3 tribbles pseudokinase 3 1.012
TSG101 tumor susceptibility 101 1.012
DPP9 dipeptidyl-peptidase 9 1.012
CTCF CCCTC-binding factor (zinc finger protein) 1.011
CD248 CD248 molecule, endosialin 1.011
JAG2 jagged 2 1.011
PTPRN protein tyrosine phosphatase, receptor type, N 1.011
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.01
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.01
LRP1 low density lipoprotein receptor-related protein 1 1.009
RNASET2 ribonuclease T2 1.009
CYTH2 cytohesin 2 1.008
LTA4H leukotriene A4 hydrolase 1.008
PKM pyruvate kinase, muscle 1.008
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 1.008
LPP LIM domain containing preferred translocation partner in lipoma 1.008
CENPE centromere protein E, 312kDa 1.008
FAP fibroblast activation protein, alpha 1.008
CMKLR1 chemerin chemokine-like receptor 1 1.008
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.007
NLRP12 NLR family, pyrin domain containing 12 1.007
VEGFB vascular endothelial growth factor B 1.007
STN1 STN1 subunit of CST complex 1.007
ACKR3 atypical chemokine receptor 3 1.006
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.006
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.005
IL27 interleukin 27 1.003
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.003
EPSTI1 epithelial stromal interaction 1 (breast) 1.003
COL8A2 collagen, type VIII, alpha 2 1.002
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.001
BMPR1A bone morphogenetic protein receptor, type IA 1.001
CDHR5 cadherin-related family member 5 1.0
HSPB1 heat shock 27kDa protein 1 1.0
EBI3 Epstein-Barr virus induced 3 1.0