Scrapie Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

337 genes co-occuring with the disease Scrapie in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PRNP prion protein 4.0
MSMB microseminoprotein, beta- 3.118
SPRN shadow of prion protein homolog (zebrafish) 3.072
PRND prion protein 2 (dublet) 2.995
SCN2A sodium channel, voltage gated, type II alpha subunit 2.965
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.765
APP amyloid beta (A4) precursor protein 2.501
RPSA ribosomal protein SA 2.379
HTT huntingtin 2.372
SCRG1 stimulator of chondrogenesis 1 2.37
GFAP glial fibrillary acidic protein 2.343
AIF1 allograft inflammatory factor 1 2.205
TARDBP TAR DNA binding protein 2.189
FYN FYN proto-oncogene, Src family tyrosine kinase 2.121
TMEM154 transmembrane protein 154 2.092
STIP1 stress-induced phosphoprotein 1 2.066
SOD1 superoxide dismutase 1, soluble 2.05
HSPA4 heat shock 70kDa protein 4 2.035
PEPD peptidase D 2.027
MAPT microtubule-associated protein tau 2.023
PDIA3 protein disulfide isomerase family A, member 3 2.012
PXDNL peroxidasin-like 1.955
PXDN peroxidasin 1.953
BACE1 beta-site APP-cleaving enzyme 1 1.948
FLOT1 flotillin 1 1.925
PLGLB1 plasminogen-like B1 1.921
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.908
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.883
ACTB actin, beta 1.877
IAPP islet amyloid polypeptide 1.875
ALB albumin 1.813
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.774
FUS FUS RNA binding protein 1.773
SSBP1 single-stranded DNA binding protein 1, mitochondrial 1.768
HSPA8 heat shock 70kDa protein 8 1.739
ADAM10 ADAM metallopeptidase domain 10 1.729
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.725
PSEN1 presenilin 1 1.723
IL1B interleukin 1, beta 1.716
APOE apolipoprotein E 1.712
TTR transthyretin 1.707
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.694
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.69
ENO2 enolase 2 (gamma, neuronal) 1.686
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.67
SYP synaptophysin 1.668
OR52W1 olfactory receptor, family 52, subfamily W, member 1 1.665
TREM2 triggering receptor expressed on myeloid cells 2 1.658
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.651
CLU clusterin 1.65
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.646
ERI3 ERI1 exoribonuclease family member 3 1.612
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.607
CPEB1 cytoplasmic polyadenylation element binding protein 1 1.599
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.584
TNF tumor necrosis factor 1.583
NGF nerve growth factor (beta polypeptide) 1.581
TXNDC9 thioredoxin domain containing 9 1.568
PADI2 peptidyl arginine deiminase, type II 1.568
STMN2 stathmin 2 1.565
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 1.561
OR56B4 olfactory receptor, family 56, subfamily B, member 4 1.559
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.557
SNAP25 synaptosomal-associated protein, 25kDa 1.539
MAP2 microtubule-associated protein 2 1.537
BDNF brain-derived neurotrophic factor 1.536
NWD2 NACHT and WD repeat domain containing 2 1.535
MAN2A1 mannosidase, alpha, class 2A, member 1 1.528
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.527
SLC39A5 solute carrier family 39 (zinc transporter), member 5 1.52
TSG101 tumor susceptibility 101 1.519
IL6 interleukin 6 1.518
ADGRG6 adhesion G protein-coupled receptor G6 1.514
CTSD cathepsin D 1.509
PRKN parkin RBR E3 ubiquitin protein ligase 1.509
SYN1 synapsin I 1.505
SLC39A14 solute carrier family 39 (zinc transporter), member 14 1.503
PINK1 PTEN induced putative kinase 1 1.503
NEFL neurofilament, light polypeptide 1.502
CFL1 cofilin 1 (non-muscle) 1.499
IL1A interleukin 1, alpha 1.485
CAV1 caveolin 1, caveolae protein, 22kDa 1.475
TFRC transferrin receptor 1.471
C1QA complement component 1, q subcomponent, A chain 1.471
MBP myelin basic protein 1.468
OR56A3 olfactory receptor, family 56, subfamily A, member 3 1.468
SQSTM1 sequestosome 1 1.457
SNCAIP synuclein, alpha interacting protein 1.457
CDK5 cyclin-dependent kinase 5 1.455
CANX calnexin 1.452
ADGRL3 adhesion G protein-coupled receptor L3 1.45
DNAH8 dynein, axonemal, heavy chain 8 1.44
AHSP alpha hemoglobin stabilizing protein 1.432
C9ORF72 chromosome 9 open reading frame 72 1.429
CTSS cathepsin S 1.428
ATG5 autophagy related 5 1.424
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.422
CFL2 cofilin 2 (muscle) 1.414
OR56A1 olfactory receptor, family 56, subfamily A, member 1 1.413
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.411
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.411
CTRB2 chymotrypsinogen B2 1.411
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.411
BSPH1 binder of sperm protein homolog 1 1.408
BCL2 B-cell CLL/lymphoma 2 1.407
APLP1 amyloid beta (A4) precursor-like protein 1 1.406
CTRB1 chymotrypsinogen B1 1.405
LAMP1 lysosomal-associated membrane protein 1 1.404
PLK3 polo-like kinase 3 1.403
CP ceruloplasmin (ferroxidase) 1.402
CYCS cytochrome c, somatic 1.398
IL34 interleukin 34 1.391
PGA5 pepsinogen 5, group I (pepsinogen A) 1.39
CALB1 calbindin 1, 28kDa 1.39
PRR4 proline rich 4 (lacrimal) 1.387
S100B S100 calcium binding protein B 1.385
OR56A4 olfactory receptor, family 56, subfamily A, member 4 1.382
CD68 CD68 molecule 1.381
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.381
PARK7 parkinson protein 7 1.38
PLG plasminogen 1.376
CREB1 cAMP responsive element binding protein 1 1.375
ITM2B integral membrane protein 2B 1.372
DLG4 discs, large homolog 4 (Drosophila) 1.368
ATF6 activating transcription factor 6 1.366
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.364
PRSS57 protease, serine, 57 1.36
PSEN2 presenilin 2 1.356
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.354
LTB lymphotoxin beta (TNF superfamily, member 3) 1.352
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.346
INS insulin 1.344
CSF1R colony stimulating factor 1 receptor 1.344
FLOT2 flotillin 2 1.343
B2M beta-2-microglobulin 1.343
OR52B2 olfactory receptor, family 52, subfamily B, member 2 1.341
ATXN3L ataxin 3-like 1.338
TP53 tumor protein p53 1.337
FAM229B family with sequence similarity 229, member B 1.337
IFNG interferon, gamma 1.337
GP2 glycoprotein 2 (zymogen granule membrane) 1.333
HSPA1B heat shock 70kDa protein 1B 1.331
TPPP tubulin polymerization promoting protein 1.33
TLR2 toll-like receptor 2 1.328
GPC1 glypican 1 1.321
PLD1 phospholipase D1, phosphatidylcholine-specific 1.314
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.31
THY1 Thy-1 cell surface antigen 1.308
ATXN1 ataxin 1 1.307
SH2D3C SH2 domain containing 3C 1.307
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.306
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.306
LRP1 low density lipoprotein receptor-related protein 1 1.299
STEAP3 STEAP family member 3, metalloreductase 1.297
TLR4 toll-like receptor 4 1.295
ADAM17 ADAM metallopeptidase domain 17 1.295
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.288
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.286
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.279
HSPA13 heat shock protein 70kDa family, member 13 1.276
TH tyrosine hydroxylase 1.275
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.273
RAB11A RAB11A, member RAS oncogene family 1.272
SYN2 synapsin II 1.27
GSK3B glycogen synthase kinase 3 beta 1.267
NCSTN nicastrin 1.265
JUN jun proto-oncogene 1.261
PVALB parvalbumin 1.257
MAPK3 mitogen-activated protein kinase 3 1.256
GRM5 glutamate receptor, metabotropic 5 1.256
TGFB1 transforming growth factor, beta 1 1.255
LIMK1 LIM domain kinase 1 1.254
CALML4 calmodulin-like 4 1.253
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.252
IL10 interleukin 10 1.25
CCL5 chemokine (C-C motif) ligand 5 1.249
GDNF glial cell derived neurotrophic factor 1.248
APLP2 amyloid beta (A4) precursor-like protein 2 1.247
ADAM9 ADAM metallopeptidase domain 9 1.247
GRB2 growth factor receptor-bound protein 2 1.247
XBP1 X-box binding protein 1 1.244
CALML6 calmodulin-like 6 1.242
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 1.241
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.24
CALML3 calmodulin-like 3 1.24
CALML5 calmodulin-like 5 1.239
CTSB cathepsin B 1.235
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.232
CPNE8 copine VIII 1.231
CSN1S1 casein alpha s1 1.231
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.229
CD4 CD4 molecule 1.227
CXCL10 chemokine (C-X-C motif) ligand 10 1.226
NEFH neurofilament, heavy polypeptide 1.225
ATXN3 ataxin 3 1.223
C1QB complement component 1, q subcomponent, B chain 1.221
MAP1B microtubule-associated protein 1B 1.218
BECN1 beclin 1, autophagy related 1.218
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.218
ATRN attractin 1.215
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.214
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.214
EEA1 early endosome antigen 1 1.206
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.205
CCL2 chemokine (C-C motif) ligand 2 1.202
NES nestin 1.201
LAMP2 lysosomal-associated membrane protein 2 1.201
ERVW-1 endogenous retrovirus group W, member 1 1.197
ACO1 aconitase 1, soluble 1.196
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.189
SH2D3A SH2 domain containing 3A 1.189
CD9 CD9 molecule 1.189
A2M alpha-2-macroglobulin 1.188
DNM1L dynamin 1-like 1.185
LGALS4 lectin, galactoside-binding, soluble, 4 1.185
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.179
CCL19 chemokine (C-C motif) ligand 19 1.179
APCS amyloid P component, serum 1.178
HSPB1 heat shock 27kDa protein 1 1.178
MAP1A microtubule-associated protein 1A 1.164
ALPP alkaline phosphatase, placental 1.163
SYN3 synapsin III 1.163
P4HB prolyl 4-hydroxylase, beta polypeptide 1.161
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 1.161
IL1R1 interleukin 1 receptor, type I 1.157
IDE insulin-degrading enzyme 1.156
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.153
OR52L1 olfactory receptor, family 52, subfamily L, member 1 1.151
RARB retinoic acid receptor, beta 1.151
IREB2 iron-responsive element binding protein 2 1.145
LGALS3 lectin, galactoside-binding, soluble, 3 1.143
SNCB synuclein, beta 1.139
CCL21 chemokine (C-C motif) ligand 21 1.139
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.136
CYBRD1 cytochrome b reductase 1 1.135
CST3 cystatin C 1.134
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 1.132
IZUMO4 IZUMO family member 4 1.129
LTA lymphotoxin alpha 1.128
CD81 CD81 molecule 1.127
CSF1 colony stimulating factor 1 (macrophage) 1.125
CTRL chymotrypsin-like 1.122
ADAM8 ADAM metallopeptidase domain 8 1.118
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.118
H1-0 H1.0 linker histone 1.118
TMEM119 transmembrane protein 119 1.118
RAB5A RAB5A, member RAS oncogene family 1.118
PTPRC protein tyrosine phosphatase, receptor type, C 1.111
RBM8A RNA binding motif protein 8A 1.109
DNM1 dynamin 1 1.101
IL1RN interleukin 1 receptor antagonist 1.099
C4A complement component 4A (Rodgers blood group) 1.098
GUSB glucuronidase, beta 1.095
USP19 ubiquitin specific peptidase 19 1.093
BAX BCL2-associated X protein 1.09
ERN1 endoplasmic reticulum to nucleus signaling 1 1.089
HSPB8 heat shock 22kDa protein 8 1.086
CD63 CD63 molecule 1.086
CFH complement factor H 1.085
SSR1 signal sequence receptor, alpha 1.085
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.084
LYN LYN proto-oncogene, Src family tyrosine kinase 1.083
MMEL1 membrane metallo-endopeptidase-like 1 1.079
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.078
RPL32 ribosomal protein L32 1.075
NOS1 nitric oxide synthase 1 (neuronal) 1.074
CALR calreticulin 1.071
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 1.07
GBP2 guanylate binding protein 2, interferon-inducible 1.07
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.069
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.068
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 1.067
CXCL13 chemokine (C-X-C motif) ligand 13 1.067
MT2A metallothionein 2A 1.066
CNTF ciliary neurotrophic factor 1.066
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.065
MARK4 MAP/microtubule affinity-regulating kinase 4 1.065
TXN thioredoxin 1.065
CD44 CD44 molecule (Indian blood group) 1.064
MAP1S microtubule-associated protein 1S 1.063
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.062
DPYSL2 dihydropyrimidinase-like 2 1.06
NCAM1 neural cell adhesion molecule 1 1.059
DICER1 dicer 1, ribonuclease type III 1.058
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 1.058
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 1.057
KIF5C kinesin family member 5C 1.055
HSPA12A heat shock 70kDa protein 12A 1.055
IFNB1 interferon, beta 1, fibroblast 1.055
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 1.054
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.054
LMAN2 lectin, mannose-binding 2 1.051
CD8A CD8a molecule 1.05
FN1 fibronectin 1 1.049
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 1.047
EGF epidermal growth factor 1.046
HSPH1 heat shock 105kDa/110kDa protein 1 1.045
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.044
COL25A1 collagen, type XXV, alpha 1 1.043
PSENEN presenilin enhancer gamma secretase subunit 1.041
CHAT choline O-acetyltransferase 1.038
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.035
EGR1 early growth response 1 1.035
CST7 cystatin F (leukocystatin) 1.035
CAPN6 calpain 6 1.034
LRRN4 leucine rich repeat neuronal 4 1.034
OPRD1 opioid receptor, delta 1 1.031
RAB4A RAB4A, member RAS oncogene family 1.031
POTEF POTE ankyrin domain family, member F 1.03
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 1.03
HMOX1 heme oxygenase 1 1.03
MT1E metallothionein 1E 1.029
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.028
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.024
DHCR24 24-dehydrocholesterol reductase 1.023
TRIT1 tRNA isopentenyltransferase 1 1.022
GLUL glutamate-ammonia ligase 1.021
MSTN myostatin 1.019
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.017
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.016
APH1A APH1A gamma secretase subunit 1.016
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 1.014
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 1.014
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 1.014
ZNF174 zinc finger protein 174 1.013
MYD88 myeloid differentiation primary response 88 1.013
GH1 growth hormone 1 1.013
MAGEE2 melanoma antigen family E2 1.013
OMA1 OMA1 zinc metallopeptidase 1.01
C3AR1 complement component 3a receptor 1 1.009
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.008
DCTN3 dynactin 3 (p22) 1.008
MAOB monoamine oxidase B 1.007
CAST calpastatin 1.004
SYT5 synaptotagmin V 1.002
ULK1 unc-51 like autophagy activating kinase 1 1.002
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.001