Scurvy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_13724)
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Genes

136 genes co-occuring with the disease Scurvy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 3.219
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 3.193
GDPGP1 GDP-D-glucose phosphorylase 1 2.627
RGN regucalcin 2.528
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.447
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 2.419
MIOX myo-inositol oxygenase 2.073
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.945
SLC23A3 solute carrier family 23, member 3 1.939
PAM peptidylglycine alpha-amidating monooxygenase 1.863
TET1 tet methylcytosine dioxygenase 1 1.859
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.859
PRDX4 peroxiredoxin 4 1.831
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.813
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.81
ERO1B endoplasmic reticulum oxidoreductase 1 beta 1.79
ALB albumin 1.774
CRP C-reactive protein, pentraxin-related 1.756
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 1.751
TET2 tet methylcytosine dioxygenase 2 1.713
TTPA tocopherol (alpha) transfer protein 1.711
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 1.709
IL6 interleukin 6 1.672
GPX7 glutathione peroxidase 7 1.652
TET3 tet methylcytosine dioxygenase 3 1.641
GPX3 glutathione peroxidase 3 1.633
GPX8 glutathione peroxidase 8 (putative) 1.631
INS insulin 1.612
GPX5 glutathione peroxidase 5 1.606
GPX2 glutathione peroxidase 2 1.601
GPX6 glutathione peroxidase 6 1.598
TNF tumor necrosis factor 1.572
IL1B interleukin 1, beta 1.57
CYB561 cytochrome b561 1.551
QSOX2 quiescin Q6 sulfhydryl oxidase 2 1.538
GSR glutathione reductase 1.532
BGLAP bone gamma-carboxyglutamate (gla) protein 1.521
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.505
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 1.486
EGLN1 egl-9 family hypoxia-inducible factor 1 1.446
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III 1.443
IL2 interleukin 2 1.428
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 1.422
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.411
F2 coagulation factor II (thrombin) 1.408
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.407
F3 coagulation factor III (thromboplastin, tissue factor) 1.4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.387
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 1.376
PTH parathyroid hormone 1.36
GLRX glutaredoxin (thioltransferase) 1.346
P3H1 prolyl 3-hydroxylase 1 1.346
KDM2A lysine (K)-specific demethylase 2A 1.339
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.334
IL10 interleukin 10 1.328
IL1A interleukin 1, alpha 1.311
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.297
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 1.297
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.296
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.289
TXN thioredoxin 1.278
IFNG interferon, gamma 1.271
NOS3 nitric oxide synthase 3 (endothelial cell) 1.263
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1.26
EGLN2 egl-9 family hypoxia-inducible factor 2 1.26
HP haptoglobin 1.247
TGFB1 transforming growth factor, beta 1 1.242
P3H2 prolyl 3-hydroxylase 2 1.237
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.234
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.229
CD4 CD4 molecule 1.229
XDH xanthine dehydrogenase 1.221
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.218
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.211
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.192
EGLN3 egl-9 family hypoxia-inducible factor 3 1.19
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 1.188
TYW5 tRNA-yW synthesizing protein 5 1.177
POMC proopiomelanocortin 1.177
NFE2L2 nuclear factor, erythroid 2-like 2 1.173
G6PD glucose-6-phosphate dehydrogenase 1.169
KDM3A lysine (K)-specific demethylase 3A 1.162
CP ceruloplasmin (ferroxidase) 1.161
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.16
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.16
EPO erythropoietin 1.155
HMOX1 heme oxygenase 1 1.154
TP53 tumor protein p53 1.15
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.149
MB myoglobin 1.147
CXCL8 chemokine (C-X-C motif) ligand 8 1.133
BCL2 B-cell CLL/lymphoma 2 1.131
ELN elastin 1.13
OXT oxytocin/neurophysin I prepropeptide 1.13
CYCS cytochrome c, somatic 1.129
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.127
COL1A1 collagen, type I, alpha 1 1.117
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.116
GPKOW G patch domain and KOW motifs 1.115
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.115
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.113
CD8A CD8a molecule 1.108
TKTL2 transketolase-like 2 1.103
PSEN1 presenilin 1 1.102
ACTB actin, beta 1.101
MPI mannose phosphate isomerase 1.099
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.094
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.089
KDM4A lysine (K)-specific demethylase 4A 1.082
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.079
PXDNL peroxidasin-like 1.076
SPP1 secreted phosphoprotein 1 1.075
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.075
DCN decorin 1.075
TKT transketolase 1.075
PXDN peroxidasin 1.074
TYR tyrosinase 1.073
GPI glucose-6-phosphate isomerase 1.072
LEP leptin 1.067
RIOX1 ribosomal oxygenase 1 1.066
IL4 interleukin 4 1.064
HAMP hepcidin antimicrobial peptide 1.063
JMJD4 jumonji domain containing 4 1.06
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 1.05
MGP matrix Gla protein 1.046
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 1.044
TKTL1 transketolase-like 1 1.044
KDM4B lysine (K)-specific demethylase 4B 1.043
MT1E metallothionein 1E 1.04
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.038
LTF lactotransferrin 1.031
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.021
FTO fat mass and obesity associated 1.016
TDG thymine-DNA glycosylase 1.012
GC group-specific component (vitamin D binding protein) 1.012
MMP1 matrix metallopeptidase 1 1.008