Secretory Diarrhea Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Secretory diarrhea is a diarrhea where there is an increase in the active secretion, or there is an inhibition of absorption causing little to no structural damage. The most common cause of this type of diarrhea is a cholera toxin that stimulates the secretion of anions, especially chloride ions. (Human Disease Ontology, DOID_0050129)
External Link https://www.disgenet.org/browser/0/1/0/C0267557
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Genes

18 genes associated with the disease Secretory Diarrhea in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ANO6 anoctamin 6
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
FOXP3 forkhead box P3
GUCA2A guanylate cyclase activator 2A (guanylin)
GUCA2B guanylate cyclase activator 2B (uroguanylin)
IL13RA1 interleukin 13 receptor, alpha 1
MYO5B myosin VB
NLRC4 NLR family, CARD domain containing 4
PLVAP plasmalemma vesicle associated protein
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TAPBP TAP binding protein (tapasin)
VIP vasoactive intestinal peptide