| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A1 | collagen, type V, alpha 1 | 0.0899978 |
| COL3A1 | collagen, type III, alpha 1 | 0.0809604 |
| AHNAK | AHNAK nucleoprotein | 0.0808662 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.060482 |
| THBS2 | thrombospondin 2 | 0.0561524 |
| COL5A2 | collagen, type V, alpha 2 | 0.0533564 |
| SEPTIN9 | septin 9 | 0.0451592 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0427461 |
| XPO1 | exportin 1 | 0.0424574 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0403636 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0399548 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0396198 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0367986 |
| APP | amyloid beta (A4) precursor protein | 0.0366767 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0366083 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0360652 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.035597 |
| CANX | calnexin | 0.0355743 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.03514 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0347955 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0345634 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0343475 |
| RND3 | Rho family GTPase 3 | 0.0337628 |
| DST | dystonin | 0.0319648 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.031729 |
| HDAC9 | histone deacetylase 9 | 0.0316173 |
| VMP1 | vacuole membrane protein 1 | 0.0304147 |
| PODXL | podocalyxin-like | 0.0300188 |
| MYOF | myoferlin | 0.029664 |
| CTSB | cathepsin B | 0.0294785 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277001 |
| FBN1 | fibrillin 1 | 0.0275237 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0269362 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.026891 |
| OGA | O-GlcNAcase | 0.0266906 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0263345 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0258593 |
| LOX | lysyl oxidase | 0.0243183 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.022364 |
| FLNA | filamin A, alpha | 0.022302 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0222808 |
| ANXA2 | annexin A2 | 0.0222277 |
| FSTL1 | follistatin-like 1 | 0.0214293 |
| LOXL2 | lysyl oxidase-like 2 | 0.0207665 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0205103 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0198224 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0196816 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0196643 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 | 0.0193374 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0193188 |
| ARRDC3 | arrestin domain containing 3 | 0.0191127 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0189695 |
| NEK7 | NIMA-related kinase 7 | 0.018901 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0171829 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0170467 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0169136 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0166243 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0166135 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.016514 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | 0.0164733 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0163604 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0162511 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0162482 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0161679 |
| FUS | FUS RNA binding protein | 0.0161389 |
| TMSB4X | thymosin beta 4, X-linked | 0.0160939 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0158045 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0156874 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0154912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0154305 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0149595 |
| ZNF217 | zinc finger protein 217 | 0.0148779 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0148494 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0148056 |
| CAVIN1 | caveolae associated protein 1 | 0.0147896 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0145864 |
| TRAM2 | translocation associated membrane protein 2 | 0.0144219 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0142342 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0141209 |
| ANXA1 | annexin A1 | 0.0139276 |
| LMO7 | LIM domain 7 | 0.013677 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0136576 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0135918 |
| SFXN3 | sideroflexin 3 | 0.0132511 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0132285 |
| CEP112 | centrosomal protein 112kDa | 0.0130417 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0129928 |
| FAT1 | FAT atypical cadherin 1 | 0.0129624 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0128815 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0128161 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0126872 |
| RNF150 | ring finger protein 150 | 0.0126298 |
| CDH13 | cadherin 13 | 0.0125497 |
| PFKP | phosphofructokinase, platelet | 0.012537 |
| SLFN5 | schlafen family member 5 | 0.0125338 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0124807 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0124001 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0123977 |
| E2F7 | E2F transcription factor 7 | 0.0123028 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0122465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.185922 |
| MT2A | metallothionein 2A | -0.169237 |
| VIM | vimentin | -0.155159 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.147051 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106441 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.105029 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0957119 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0898509 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0810098 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0671993 |
| NDRG1 | N-myc downstream regulated 1 | -0.0623823 |
| S100A10 | S100 calcium binding protein A10 | -0.0578121 |
| CSTB | cystatin B (stefin B) | -0.0574671 |
| MT1X | metallothionein 1X | -0.0562797 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0562687 |
| PLAT | plasminogen activator, tissue | -0.0498615 |
| S100A6 | S100 calcium binding protein A6 | -0.0404871 |
| LMNA | lamin A/C | -0.0379706 |
| GPC6 | glypican 6 | -0.0367108 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0366021 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0348711 |
| HLA-B | major histocompatibility complex, class I, B | -0.0340834 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0333864 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0321994 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0311699 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0289348 |
| CD44 | CD44 molecule (Indian blood group) | -0.0271308 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0262009 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0261831 |
| RPS19 | ribosomal protein S19 | -0.0258538 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0252264 |
| PTMA | prothymosin, alpha | -0.0251434 |
| MX2 | MX dynamin-like GTPase 2 | -0.0250197 |
| AUTS2 | autism susceptibility candidate 2 | -0.0249066 |
| RSF1 | remodeling and spacing factor 1 | -0.0242912 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.022912 |
| PRSS23 | protease, serine, 23 | -0.0228167 |
| PFN1 | profilin 1 | -0.0227436 |
| SBF2 | SET binding factor 2 | -0.0225162 |
| NAV1 | neuron navigator 1 | -0.0224621 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0219159 |
| RPL28 | ribosomal protein L28 | -0.0218898 |
| RPL37A | ribosomal protein L37a | -0.0217497 |
| RPS6 | ribosomal protein S6 | -0.0215439 |
| RPL35A | ribosomal protein L35a | -0.0214006 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0210906 |
| SUCNR1 | succinate receptor 1 | -0.0207329 |
| S100A11 | S100 calcium binding protein A11 | -0.0206628 |
| B2M | beta-2-microglobulin | -0.0206311 |
| SEC61G | Sec61 gamma subunit | -0.020523 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0200009 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0194375 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0194312 |
| MYADM | myeloid-associated differentiation marker | -0.0191261 |
| S100A4 | S100 calcium binding protein A4 | -0.0190178 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0187743 |
| RPS8 | ribosomal protein S8 | -0.0184815 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0183094 |
| RPL23 | ribosomal protein L23 | -0.0182285 |
| SMIM44 | small integral membrane protein 44 | -0.0180352 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0180055 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0179688 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0177068 |
| SETD5 | SET domain containing 5 | -0.017611 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0172746 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0171441 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0169977 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0169142 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0169078 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0168978 |
| VCL | vinculin | -0.0167808 |
| RPS14 | ribosomal protein S14 | -0.0166345 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.01659 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0165706 |
| POTEF | POTE ankyrin domain family, member F | -0.0164905 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0164754 |
| SP100 | SP100 nuclear antigen | -0.0164303 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0163494 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0162501 |
| GOLGA4 | golgin A4 | -0.0160818 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0159343 |
| RPS13 | ribosomal protein S13 | -0.0158538 |
| RBM25 | RNA binding motif protein 25 | -0.0158116 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0158095 |
| RPL34 | ribosomal protein L34 | -0.0157401 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0156229 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0153936 |
| UBC | ubiquitin C | -0.0152762 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0151812 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0151261 |
| RRBP1 | ribosome binding protein 1 | -0.0150933 |
| CMIP | c-Maf inducing protein | -0.014993 |
| RPL9 | ribosomal protein L9 | -0.0149532 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0148959 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0146748 |
| RPL36 | ribosomal protein L36 | -0.0145914 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0145686 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0144942 |
| ADM | adrenomedullin | -0.0144758 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0142156 |
