| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.0838586 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0797138 |
| NRXN3 | neurexin 3 | 0.0526719 |
| WWOX | WW domain containing oxidoreductase | 0.0469618 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0446187 |
| XPO1 | exportin 1 | 0.0438977 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0438646 |
| PCDH9 | protocadherin 9 | 0.0385551 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0357063 |
| NEGR1 | neuronal growth regulator 1 | 0.0348985 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0344983 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0343696 |
| VMP1 | vacuole membrane protein 1 | 0.0330506 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0322859 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0317904 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0317685 |
| MACROD2 | MACRO domain containing 2 | 0.031374 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0306985 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0296468 |
| YAP1 | Yes-associated protein 1 | 0.0295898 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0294464 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.02935 |
| JMJD1C | jumonji domain containing 1C | 0.029304 |
| ARRDC3 | arrestin domain containing 3 | 0.0287695 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0284976 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0269743 |
| FHIT | fragile histidine triad | 0.0268762 |
| OGA | O-GlcNAcase | 0.0266872 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0262276 |
| ANK2 | ankyrin 2, neuronal | 0.0259846 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0257085 |
| PCBP2 | poly(rC) binding protein 2 | 0.0254335 |
| CCNL1 | cyclin L1 | 0.025413 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0248072 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0247939 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0244601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0238159 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0235201 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0231835 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0231012 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0229231 |
| PRKCE | protein kinase C, epsilon | 0.0222101 |
| DENND5A | DENN/MADD domain containing 5A | 0.0218496 |
| RNF150 | ring finger protein 150 | 0.0211836 |
| INTS6 | integrator complex subunit 6 | 0.02075 |
| MYOM1 | myomesin 1 | 0.0207026 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0203844 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0202386 |
| RPS6 | ribosomal protein S6 | 0.0201235 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0199241 |
| BRD2 | bromodomain containing 2 | 0.0199155 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0185795 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0183403 |
| RTN4 | reticulon 4 | 0.018305 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0179516 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0177468 |
| RPS12 | ribosomal protein S12 | 0.0176167 |
| GPHN | gephyrin | 0.0175088 |
| PREPL | prolyl endopeptidase-like | 0.0175 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0173727 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0172677 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0170465 |
| FLNA | filamin A, alpha | 0.0168661 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0165607 |
| SUMF1 | sulfatase modifying factor 1 | 0.016529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0165105 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0163369 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0160242 |
| USP53 | ubiquitin specific peptidase 53 | 0.0160165 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0159881 |
| CCNG2 | cyclin G2 | 0.0159821 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0159299 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0158488 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0158053 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0157749 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0156785 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.015549 |
| TPM3 | tropomyosin 3 | 0.0154861 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.015408 |
| MYOF | myoferlin | 0.0153579 |
| CPOX | coproporphyrinogen oxidase | 0.0152517 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | 0.0152463 |
| PRELID2 | PRELI domain containing 2 | 0.0151782 |
| MYO10 | myosin X | 0.0151675 |
| NGFR | nerve growth factor receptor | 0.0151442 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.015134 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0148308 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0148123 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0147543 |
| HELZ | helicase with zinc finger | 0.0146751 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.014651 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0145623 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.014439 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0143939 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0143612 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0141859 |
| FAT1 | FAT atypical cadherin 1 | 0.0141394 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.014088 |
| EPHA5 | EPH receptor A5 | 0.0139753 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0139079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.201567 |
| MMP12 | matrix metallopeptidase 12 | -0.100943 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0860906 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0838452 |
| CLDN1 | claudin 1 | -0.0682424 |
| PCDH7 | protocadherin 7 | -0.0674131 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.066228 |
| LMO7 | LIM domain 7 | -0.0647548 |
| VIM | vimentin | -0.0631204 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0602065 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.059748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0592782 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0574598 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0547199 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0510346 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0505193 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0493758 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0482862 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0481524 |
| BCHE | butyrylcholinesterase | -0.0466293 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0459491 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0450688 |
| DST | dystonin | -0.0441335 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0439805 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0424487 |
| KIF5B | kinesin family member 5B | -0.0420414 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0419006 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0418914 |
| AHNAK | AHNAK nucleoprotein | -0.0412219 |
| ECT2 | epithelial cell transforming 2 | -0.0401722 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396216 |
| HMGA2 | high mobility group AT-hook 2 | -0.0385523 |
| CENPF | centromere protein F, 350/400kDa | -0.0382357 |
| MKI67 | marker of proliferation Ki-67 | -0.0378693 |
| TXNRD1 | thioredoxin reductase 1 | -0.0375838 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0367796 |
| H1-0 | H1.0 linker histone | -0.0355522 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0344135 |
| TENM3 | teneurin transmembrane protein 3 | -0.034358 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0339116 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0338585 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0337271 |
| TMSB10 | thymosin beta 10 | -0.0337028 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.03354 |
| MTAP | methylthioadenosine phosphorylase | -0.032762 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0315264 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0314782 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0313619 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0307716 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303298 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0302755 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0299143 |
| MAP1B | microtubule-associated protein 1B | -0.0295336 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0288723 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.028843 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0287799 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0286949 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281292 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0281179 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0275696 |
| EHBP1 | EH domain binding protein 1 | -0.0270553 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0268325 |
| TMEM123 | transmembrane protein 123 | -0.0267934 |
| CENPE | centromere protein E, 312kDa | -0.0267589 |
| TUBB | tubulin, beta class I | -0.0265352 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0263698 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0262646 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261916 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0260661 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0260061 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0258673 |
| VCL | vinculin | -0.0256283 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0254734 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0253849 |
| NEBL | nebulette | -0.0250767 |
| ADIPOR2 | adiponectin receptor 2 | -0.0249452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248536 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0244207 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0243638 |
| ACTG1 | actin gamma 1 | -0.0243222 |
| MYPN | myopalladin | -0.024308 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0242454 |
| MAP4 | microtubule-associated protein 4 | -0.024236 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0240358 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0239702 |
| RASAL2 | RAS protein activator like 2 | -0.0238924 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0238667 |
| HDLBP | high density lipoprotein binding protein | -0.0232917 |
| ZNF217 | zinc finger protein 217 | -0.0232703 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0231101 |
| WDR43 | WD repeat domain 43 | -0.0229396 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.022923 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0227791 |
| NAV3 | neuron navigator 3 | -0.0226989 |
| TMEM131 | transmembrane protein 131 | -0.0226486 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0226467 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0224647 |
| NEK7 | NIMA-related kinase 7 | -0.0222714 |
| ANXA1 | annexin A1 | -0.0221604 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0218709 |
