| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.160177 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.138171 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0865009 |
| OGA | O-GlcNAcase | 0.0699693 |
| EMP1 | epithelial membrane protein 1 | 0.0636903 |
| UPP1 | uridine phosphorylase 1 | 0.0636532 |
| XPO1 | exportin 1 | 0.0603826 |
| SDC4 | syndecan 4 | 0.0590849 |
| TXNRD1 | thioredoxin reductase 1 | 0.0515564 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0494193 |
| SMAD3 | SMAD family member 3 | 0.0363254 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0354102 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0353497 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0343811 |
| SGMS2 | sphingomyelin synthase 2 | 0.0327444 |
| ARRDC3 | arrestin domain containing 3 | 0.0327184 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0325062 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0313384 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0304984 |
| FAM107B | family with sequence similarity 107, member B | 0.0303185 |
| TUFT1 | tuftelin 1 | 0.0285733 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0284137 |
| FAM13A | family with sequence similarity 13, member A | 0.0283661 |
| ITGB8 | integrin, beta 8 | 0.0282624 |
| FHL2 | four and a half LIM domains 2 | 0.0249885 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0245557 |
| SEPTIN9 | septin 9 | 0.024396 |
| SLTM | SAFB-like, transcription modulator | 0.0243503 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0241359 |
| ACVR1 | activin A receptor, type I | 0.0238041 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0237759 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0237524 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0236417 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229767 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0227129 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.021676 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210598 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0206388 |
| MCL1 | myeloid cell leukemia 1 | 0.0202375 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0198174 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0191038 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.019095 |
| RLIM | ring finger protein, LIM domain interacting | 0.0188148 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0187967 |
| ANXA1 | annexin A1 | 0.0186326 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0184919 |
| FNBP4 | formin binding protein 4 | 0.0182249 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0181101 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0180862 |
| TXNIP | thioredoxin interacting protein | 0.0179923 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0173423 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.0171277 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0168558 |
| ANO10 | anoctamin 10 | 0.0167946 |
| DMXL1 | Dmx-like 1 | 0.0167661 |
| DENND4C | DENN/MADD domain containing 4C | 0.0165507 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0164613 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0162969 |
| CTSB | cathepsin B | 0.0161815 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0161193 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0160484 |
| OPTN | optineurin | 0.0159189 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0157847 |
| AHR | aryl hydrocarbon receptor | 0.0157776 |
| TGM2 | transglutaminase 2 | 0.0157551 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.015732 |
| MLF1 | myeloid leukemia factor 1 | 0.0155 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.0153924 |
| CBFB | core-binding factor, beta subunit | 0.0153557 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0148587 |
| BIN3 | bridging integrator 3 | 0.0143209 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0142708 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.014223 |
| MCC | mutated in colorectal cancers | 0.0141849 |
| ATF3 | activating transcription factor 3 | 0.0141649 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0141183 |
| APP | amyloid beta (A4) precursor protein | 0.0139808 |
| YTHDC1 | YTH domain containing 1 | 0.0139218 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0138969 |
| ZNF462 | zinc finger protein 462 | 0.0138799 |
| SH3PXD2A | SH3 and PX domains 2A | 0.013813 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0136666 |
| RASA3 | RAS p21 protein activator 3 | 0.013592 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0135694 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0134936 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0133589 |
| ADM | adrenomedullin | 0.0132775 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0132391 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0130362 |
| CD47 | CD47 molecule | 0.0129066 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0128236 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0128062 |
| TRRAP | transformation/transcription domain-associated protein | 0.0126056 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0124261 |
| STK17B | serine/threonine kinase 17b | 0.012349 |
| OTUD7B | OTU deubiquitinase 7B | 0.0121337 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.0120758 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0120128 |
| GPHN | gephyrin | 0.011925 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0119144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.204402 |
| TMSB10 | thymosin beta 10 | -0.198604 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.125013 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.12234 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.111982 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.107342 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.091522 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0896124 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0876393 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0842009 |
| ASPH | aspartate beta-hydroxylase | -0.0837569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.081569 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0773653 |
| FLNB | filamin B, beta | -0.0769159 |
| LAMA4 | laminin, alpha 4 | -0.0761005 |
| DIAPH2 | diaphanous-related formin 2 | -0.0721797 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0712096 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.068691 |
| LAMC2 | laminin, gamma 2 | -0.0628159 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0613428 |
| HMGA1 | high mobility group AT-hook 1 | -0.0610749 |
| NPSR1 | neuropeptide S receptor 1 | -0.0603751 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0602171 |
| LAMB3 | laminin, beta 3 | -0.0596119 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0595302 |
| FBXO11 | F-box protein 11 | -0.0575539 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0553532 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0537698 |
| ITGA6 | integrin, alpha 6 | -0.0534746 |
| ANXA2 | annexin A2 | -0.0528928 |
| KLK10 | kallikrein-related peptidase 10 | -0.0519988 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0511659 |
| RASAL2 | RAS protein activator like 2 | -0.0508391 |
| TJP1 | tight junction protein 1 | -0.0504694 |
| RPS21 | ribosomal protein S21 | -0.050323 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0495212 |
| VCL | vinculin | -0.0488077 |
| RRBP1 | ribosome binding protein 1 | -0.048497 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0467434 |
| LMO7 | LIM domain 7 | -0.0465104 |
| S100A10 | S100 calcium binding protein A10 | -0.0461702 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0454757 |
| RPL23 | ribosomal protein L23 | -0.0440353 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.042049 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0420033 |
| RPS3 | ribosomal protein S3 | -0.0414564 |
| GNAS | GNAS complex locus | -0.0412624 |
| FERMT1 | fermitin family member 1 | -0.0412082 |
| RPL12 | ribosomal protein L12 | -0.0411989 |
| RPL37A | ribosomal protein L37a | -0.0409487 |
| UBC | ubiquitin C | -0.0406716 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.040609 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.040397 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.039903 |
| SP100 | SP100 nuclear antigen | -0.0395194 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0390091 |
| RCOR1 | REST corepressor 1 | -0.0387076 |
| INTS6 | integrator complex subunit 6 | -0.0386763 |
| USP34 | ubiquitin specific peptidase 34 | -0.0385767 |
| PERP | PERP, TP53 apoptosis effector | -0.0382713 |
| RPLP2 | ribosomal protein, large, P2 | -0.0382521 |
| NBEAL1 | neurobeachin-like 1 | -0.0382362 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0377903 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0376996 |
| PTMA | prothymosin, alpha | -0.0376335 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0373685 |
| POTEF | POTE ankyrin domain family, member F | -0.0372249 |
| CCDC88A | coiled-coil domain containing 88A | -0.0370142 |
| TMEM263 | transmembrane protein 263 | -0.0369347 |
| ACTG1 | actin gamma 1 | -0.0368496 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0366971 |
| SPAG9 | sperm associated antigen 9 | -0.0365014 |
| PRRC2C | proline-rich coiled-coil 2C | -0.036437 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0363654 |
| FTL | ferritin, light polypeptide | -0.0353258 |
| S100A4 | S100 calcium binding protein A4 | -0.0352551 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.035058 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0349941 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0348885 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0348289 |
| RPL34 | ribosomal protein L34 | -0.0344091 |
| VIM | vimentin | -0.0342339 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0341934 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0341376 |
| MYOF | myoferlin | -0.0340589 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0340294 |
| PARD3 | par-3 family cell polarity regulator | -0.0340017 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0337259 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0333398 |
| RPS6 | ribosomal protein S6 | -0.0333142 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.033083 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0330463 |
| PRSS3 | protease, serine, 3 | -0.0329561 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0327486 |
| MORF4L2 | mortality factor 4 like 2 | -0.0327484 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0326709 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324346 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031969 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0317763 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0317196 |
