| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.110671 |
| CEP250 | centrosomal protein 250kDa | 0.0678281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0641735 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0627078 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0558495 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0550917 |
| ANKRD36C | ankyrin repeat domain 36C | 0.053284 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0476065 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0406814 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0389765 |
| HLA-B | major histocompatibility complex, class I, B | 0.0376839 |
| GOLGB1 | golgin B1 | 0.0375026 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0371759 |
| RAD51B | RAD51 paralog B | 0.0369233 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0365001 |
| SP100 | SP100 nuclear antigen | 0.0363594 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0359858 |
| CDK12 | cyclin-dependent kinase 12 | 0.0358913 |
| VEGFA | vascular endothelial growth factor A | 0.0350879 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.03407 |
| PLSCR1 | phospholipid scramblase 1 | 0.0320704 |
| INTS6 | integrator complex subunit 6 | 0.0311831 |
| RAI14 | retinoic acid induced 14 | 0.0308407 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0308288 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0304746 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0302581 |
| PRELID2 | PRELI domain containing 2 | 0.0292223 |
| RNF213 | ring finger protein 213 | 0.0280998 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.026382 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0263776 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0256163 |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 | 0.0248137 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0244095 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237064 |
| CCNG2 | cyclin G2 | 0.0233823 |
| S100P | S100 calcium binding protein P | 0.0233409 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0229014 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0227084 |
| FHIT | fragile histidine triad | 0.0224869 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0218488 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0214582 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0211306 |
| ETV6 | ets variant 6 | 0.0210984 |
| MMP24OS | MMP24 opposite strand | 0.02099 |
| USO1 | USO1 vesicle transport factor | 0.020938 |
| BPTF | bromodomain PHD finger transcription factor | 0.0207204 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.020371 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0202904 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0202167 |
| SBF2 | SET binding factor 2 | 0.0200353 |
| OGA | O-GlcNAcase | 0.0200109 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0198873 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0195761 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0191109 |
| MLPH | melanophilin | 0.0189871 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0188857 |
| RBM47 | RNA binding motif protein 47 | 0.0184986 |
| KRT86 | keratin 86, type II | 0.0184532 |
| DSPP | dentin sialophosphoprotein | 0.0183344 |
| SULF2 | sulfatase 2 | 0.0179949 |
| ZNF841 | zinc finger protein 841 | 0.0177588 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0176603 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0170852 |
| LASP1NB | LASP1 neighbor | 0.0170457 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0169348 |
| PMP22 | peripheral myelin protein 22 | 0.01693 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0166198 |
| FGB | fibrinogen beta chain | 0.0165972 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0164396 |
| PGM3 | phosphoglucomutase 3 | 0.0162811 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.0159561 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0158412 |
| DNHD1 | dynein heavy chain domain 1 | 0.0158333 |
| B2M | beta-2-microglobulin | 0.0157402 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0157346 |
| MX1 | MX dynamin-like GTPase 1 | 0.015574 |
| AEBP2 | AE binding protein 2 | 0.015474 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | 0.0154478 |
| UBAP2L | ubiquitin associated protein 2-like | 0.015322 |
| STXBP1 | syntaxin binding protein 1 | 0.0152456 |
| SLFN5 | schlafen family member 5 | 0.0152308 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0148927 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0148715 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0148597 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0146302 |
| COPA | coatomer protein complex, subunit alpha | 0.0146115 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0144467 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0143911 |
| EHBP1 | EH domain binding protein 1 | 0.0143242 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0141035 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0140131 |
| HDAC4 | histone deacetylase 4 | 0.0139607 |
| DGLUCY | D-glutamate cyclase | 0.0139584 |
| NTN4 | netrin 4 | 0.0138871 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0138468 |
| CCDC57 | coiled-coil domain containing 57 | 0.0138433 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0137922 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0137661 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0136963 |
| ANXA3 | annexin A3 | 0.0136922 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.281709 |
| RPL19 | ribosomal protein L19 | -0.261385 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.155147 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.134481 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129248 |
| MT2A | metallothionein 2A | -0.110284 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0967394 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0777957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0772564 |
| TMSB10 | thymosin beta 10 | -0.0761952 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0644417 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0620255 |
| CLTC | clathrin, heavy chain (Hc) | -0.0586354 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0574562 |
| RPL35A | ribosomal protein L35a | -0.0574366 |
| S100A9 | S100 calcium binding protein A9 | -0.0572267 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0560895 |
| GNAS | GNAS complex locus | -0.0526676 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0517745 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0512587 |
| S100A8 | S100 calcium binding protein A8 | -0.0503766 |
| PTMA | prothymosin, alpha | -0.0477158 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0475045 |
| ACACA | acetyl-CoA carboxylase alpha | -0.046444 |
| CCNI | cyclin I | -0.0436792 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0418714 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0415985 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0402988 |
| TMEM123 | transmembrane protein 123 | -0.039057 |
| FTL | ferritin, light polypeptide | -0.0387211 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0384245 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0383189 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0373474 |
| DTNA | dystrobrevin, alpha | -0.0373434 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0373059 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0370929 |
| RPL35 | ribosomal protein L35 | -0.0367479 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363479 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0362871 |
| TXNRD1 | thioredoxin reductase 1 | -0.0355892 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0354943 |
| TMSB4X | thymosin beta 4, X-linked | -0.035302 |
| AREG | amphiregulin | -0.0346203 |
| RPS6 | ribosomal protein S6 | -0.0344703 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0341244 |
| RPS19 | ribosomal protein S19 | -0.0338248 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336973 |
| JMJD1C | jumonji domain containing 1C | -0.0330897 |
| MYO1B | myosin IB | -0.0327957 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0326906 |
| PFDN4 | prefoldin subunit 4 | -0.0324768 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0324655 |
| IPO7 | importin 7 | -0.0323406 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0317507 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0312904 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0311461 |
| OLA1 | Obg-like ATPase 1 | -0.0310178 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0308823 |
| CCND1 | cyclin D1 | -0.0307934 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0307838 |
| MIEN1 | migration and invasion enhancer 1 | -0.0307698 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0307068 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0306315 |
| RPL8 | ribosomal protein L8 | -0.0305174 |
| CAB39 | calcium binding protein 39 | -0.0304421 |
| RPL32 | ribosomal protein L32 | -0.0303275 |
| WWC1 | WW and C2 domain containing 1 | -0.0294633 |
| TMEM165 | transmembrane protein 165 | -0.0294284 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0292869 |
| SRPK2 | SRSF protein kinase 2 | -0.0286115 |
| KRT8 | keratin 8, type II | -0.0285269 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0282782 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0282387 |
| TC2N | tandem C2 domains, nuclear | -0.0280687 |
| S100A14 | S100 calcium binding protein A14 | -0.0279438 |
| S100A6 | S100 calcium binding protein A6 | -0.0278618 |
| ZNF217 | zinc finger protein 217 | -0.027818 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0277985 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0276688 |
| RPL12 | ribosomal protein L12 | -0.0275549 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0270247 |
| AHNAK | AHNAK nucleoprotein | -0.0270081 |
| RPS29 | ribosomal protein S29 | -0.0267846 |
| S100A7 | S100 calcium binding protein A7 | -0.0266872 |
| RPS16 | ribosomal protein S16 | -0.0266826 |
| TBK1 | TANK-binding kinase 1 | -0.0265213 |
| RPL7A | ribosomal protein L7a | -0.0265147 |
| POTEF | POTE ankyrin domain family, member F | -0.0264626 |
| ANXA2 | annexin A2 | -0.0262541 |
| STRBP | spermatid perinuclear RNA binding protein | -0.025929 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.025432 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0253795 |
| PCBP2 | poly(rC) binding protein 2 | -0.0251587 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0250937 |
| RPLP0 | ribosomal protein, large, P0 | -0.0249908 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0247552 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0247416 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0247089 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0244428 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0243713 |
