| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Selinexor _C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF150 | ring finger protein 150 | 0.0898334 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0722946 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.047066 |
| XPO1 | exportin 1 | 0.0461806 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0457569 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0455173 |
| NEBL | nebulette | 0.0358267 |
| DMXL1 | Dmx-like 1 | 0.0353418 |
| DIXDC1 | DIX domain containing 1 | 0.0318185 |
| PRTG | protogenin | 0.0315555 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0298428 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | 0.0294041 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.0265489 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0252174 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0250699 |
| NGFR | nerve growth factor receptor | 0.024734 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0243087 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.023787 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0234577 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0225515 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0223461 |
| ZNF146 | zinc finger protein 146 | 0.0221593 |
| GPHN | gephyrin | 0.021412 |
| OTUD7B | OTU deubiquitinase 7B | 0.0211415 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0208731 |
| FMNL2 | formin-like 2 | 0.0206521 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0204527 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0197054 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0186677 |
| RAI14 | retinoic acid induced 14 | 0.0186525 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0185727 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0185136 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0181389 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0176862 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.0175686 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0174746 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.017438 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0174295 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0173003 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0172315 |
| NAF1 | nuclear assembly factor 1 ribonucleoprotein | 0.0167269 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0164841 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.0164778 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0164705 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0162153 |
| VRK2 | vaccinia related kinase 2 | 0.0161121 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0160131 |
| ANO10 | anoctamin 10 | 0.0158581 |
| CCDC57 | coiled-coil domain containing 57 | 0.0154671 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0154366 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0154095 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit | 0.0153602 |
| ZNF609 | zinc finger protein 609 | 0.0153341 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0148127 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0143445 |
| MACROD1 | MACRO domain containing 1 | 0.0141688 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0140785 |
| TLK2 | tousled-like kinase 2 | 0.0140441 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 | 0.0139894 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0139538 |
| CDK12 | cyclin-dependent kinase 12 | 0.0138475 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0138111 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0137208 |
| TMEM178B | transmembrane protein 178B | 0.0136377 |
| CUX1 | cut-like homeobox 1 | 0.0133943 |
| ARRDC3 | arrestin domain containing 3 | 0.0133592 |
| R3HDM2 | R3H domain containing 2 | 0.0133441 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0132773 |
| RNF220 | ring finger protein 220 | 0.0132412 |
| CENPF | centromere protein F, 350/400kDa | 0.0130786 |
| HMGA1 | high mobility group AT-hook 1 | 0.013032 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0129561 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0129336 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0129268 |
| SLTM | SAFB-like, transcription modulator | 0.0128684 |
| TBCD | tubulin folding cofactor D | 0.0127877 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.012755 |
| ANKRD13A | ankyrin repeat domain 13A | 0.0126817 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0126563 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0126523 |
| XPO6 | exportin 6 | 0.0125577 |
| KIAA1671 | KIAA1671 | 0.0125542 |
| DENND4C | DENN/MADD domain containing 4C | 0.0124456 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0123601 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | 0.012213 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0122025 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0119027 |
| HCFC1 | host cell factor C1 | 0.0118799 |
| CAPN5 | calpain 5 | 0.0118671 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.0118247 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0116641 |
| CLCN2 | chloride channel, voltage-sensitive 2 | 0.0113566 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0112619 |
| MEF2A | myocyte enhancer factor 2A | 0.0112232 |
| FMNL3 | formin-like 3 | 0.0112155 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.011024 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0110061 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0109717 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.010955 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0108661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148418 |
| UBC | ubiquitin C | -0.128637 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.111114 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.101722 |
| RPL23 | ribosomal protein L23 | -0.0883882 |
| TMSB10 | thymosin beta 10 | -0.0776332 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0685653 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0682394 |
| JMJD1C | jumonji domain containing 1C | -0.0681352 |
| RPS8 | ribosomal protein S8 | -0.0673658 |
| GNAS | GNAS complex locus | -0.0640901 |
| SMYD3 | SET and MYND domain containing 3 | -0.0629698 |
| PTMA | prothymosin, alpha | -0.06242 |
| B2M | beta-2-microglobulin | -0.0620831 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.062025 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0601597 |
| RPS6 | ribosomal protein S6 | -0.0591135 |
| RPS27A | ribosomal protein S27a | -0.0580495 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0577519 |
| NFIA | nuclear factor I/A | -0.0575953 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0563347 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.056181 |
| SEPTIN7 | septin 7 | -0.0551034 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.054919 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0523548 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0523099 |
| ENO1 | enolase 1, (alpha) | -0.052238 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0515572 |
| RPS19 | ribosomal protein S19 | -0.0496801 |
| RPLP1 | ribosomal protein, large, P1 | -0.0494799 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0470991 |
| RPS4X | ribosomal protein S4, X-linked | -0.0469665 |
| RTN4 | reticulon 4 | -0.0467939 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0466683 |
| RPL36 | ribosomal protein L36 | -0.0462987 |
| RPL28 | ribosomal protein L28 | -0.0460651 |
| RPL31 | ribosomal protein L31 | -0.0455139 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0454928 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.045487 |
| EGR1 | early growth response 1 | -0.0453569 |
| WDR45B | WD repeat domain 45B | -0.0453512 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0453384 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0447093 |
| MED13L | mediator complex subunit 13-like | -0.0446194 |
| RPL26 | ribosomal protein L26 | -0.0443545 |
| RPS5 | ribosomal protein S5 | -0.0442109 |
| RPS21 | ribosomal protein S21 | -0.044058 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.043926 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0438828 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0432219 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0432138 |
| RPL11 | ribosomal protein L11 | -0.0425753 |
| ZNF292 | zinc finger protein 292 | -0.0421483 |
| RPL5 | ribosomal protein L5 | -0.0421351 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0418913 |
| USP34 | ubiquitin specific peptidase 34 | -0.0418894 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0418862 |
| RPLP2 | ribosomal protein, large, P2 | -0.0417022 |
| DST | dystonin | -0.0414567 |
| RPL32 | ribosomal protein L32 | -0.0413938 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0410561 |
| PGK1 | phosphoglycerate kinase 1 | -0.0409414 |
| KIAA1958 | KIAA1958 | -0.0405403 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0405399 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404893 |
| RPS11 | ribosomal protein S11 | -0.039849 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0397742 |
| COL5A2 | collagen, type V, alpha 2 | -0.0394411 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0393946 |
| RPL37A | ribosomal protein L37a | -0.0389999 |
| RPS24 | ribosomal protein S24 | -0.0382586 |
| ENAH | enabled homolog (Drosophila) | -0.0381131 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0378328 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.037736 |
| RPL34 | ribosomal protein L34 | -0.0376813 |
| TOX | thymocyte selection-associated high mobility group box | -0.0372668 |
| FBXO11 | F-box protein 11 | -0.0369239 |
| NFIB | nuclear factor I/B | -0.0369126 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0369061 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0366828 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0364962 |
| RPS3 | ribosomal protein S3 | -0.0364818 |
| JUN | jun proto-oncogene | -0.0363934 |
| EFNA5 | ephrin-A5 | -0.036054 |
| RBM25 | RNA binding motif protein 25 | -0.0358436 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0356264 |
| RPL12 | ribosomal protein L12 | -0.0355967 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0354781 |
| RPS29 | ribosomal protein S29 | -0.0354246 |
| FAM162A | family with sequence similarity 162, member A | -0.0353124 |
| BBX | bobby sox homolog (Drosophila) | -0.0345916 |
| RPL19 | ribosomal protein L19 | -0.0345667 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0340562 |
| PEG10 | paternally expressed 10 | -0.0340064 |
| PHF21A | PHD finger protein 21A | -0.0337967 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0336757 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0335903 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0333692 |
| FOXO3 | forkhead box O3 | -0.0331384 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0328662 |