| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.14034 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.114099 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0815854 |
| CD109 | CD109 molecule | 0.0657968 |
| NDRG1 | N-myc downstream regulated 1 | 0.0645507 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0608903 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0539583 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0493382 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0440922 |
| VMP1 | vacuole membrane protein 1 | 0.0412554 |
| RNF150 | ring finger protein 150 | 0.0384749 |
| NAV2 | neuron navigator 2 | 0.0383867 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0368001 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0345151 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0336875 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0311354 |
| ADM | adrenomedullin | 0.0306987 |
| COPA | coatomer protein complex, subunit alpha | 0.030619 |
| XPO1 | exportin 1 | 0.0300914 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0298225 |
| TMEM255B | transmembrane protein 255B | 0.0297705 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296479 |
| CABIN1 | calcineurin binding protein 1 | 0.0288377 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0286256 |
| PRELID2 | PRELI domain containing 2 | 0.0285914 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0285124 |
| ASPH | aspartate beta-hydroxylase | 0.0276114 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0261268 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0260018 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0258592 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0253134 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0253082 |
| ANO10 | anoctamin 10 | 0.0252008 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0249157 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0247905 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0245766 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0241826 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.024033 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0235879 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0231332 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0229361 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0228131 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0227637 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.022546 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0225137 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0223753 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0220582 |
| ANO6 | anoctamin 6 | 0.0215711 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213092 |
| STK32A | serine/threonine kinase 32A | 0.0212958 |
| MYO1E | myosin IE | 0.0209153 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0207378 |
| SEPTIN9 | septin 9 | 0.0206843 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0206573 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0206341 |
| FOSL1 | FOS-like antigen 1 | 0.0206322 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0205147 |
| CCNL1 | cyclin L1 | 0.0204398 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0203878 |
| PARVB | parvin, beta | 0.020256 |
| MCL1 | myeloid cell leukemia 1 | 0.0196027 |
| FMNL2 | formin-like 2 | 0.0195006 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0194888 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0194338 |
| ATXN1 | ataxin 1 | 0.0193926 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0192101 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0191512 |
| VEGFA | vascular endothelial growth factor A | 0.0190693 |
| AFDN | afadin, adherens junction formation factor | 0.0189246 |
| SEC24A | SEC24 family member A | 0.0188706 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.018588 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0183691 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0183167 |
| SMYD3 | SET and MYND domain containing 3 | 0.0182385 |
| STRIP2 | striatin interacting protein 2 | 0.0181591 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0179249 |
| ANK2 | ankyrin 2, neuronal | 0.0176466 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0175495 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0172918 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.017279 |
| DMXL1 | Dmx-like 1 | 0.0171745 |
| KLF10 | Kruppel-like factor 10 | 0.016849 |
| NBAS | neuroblastoma amplified sequence | 0.0168143 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0167817 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0167175 |
| RYBP | RING1 and YY1 binding protein | 0.0166545 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0165899 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0165441 |
| ARFGEF3 | ARFGEF family member 3 | 0.0164639 |
| EXT1 | exostosin glycosyltransferase 1 | 0.016104 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0159466 |
| NUP58 | nucleoporin 58 | 0.0158241 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0157883 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0157637 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0157603 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0156887 |
| GPHN | gephyrin | 0.0156495 |
| AFAP1 | actin filament associated protein 1 | 0.0154913 |
| RASA3 | RAS p21 protein activator 3 | 0.0152783 |
| OTUD7B | OTU deubiquitinase 7B | 0.0152619 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.191824 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.181697 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179829 |
| FMN1 | formin 1 | -0.165416 |
| VIM | vimentin | -0.110574 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.102233 |
| FN1 | fibronectin 1 | -0.0881316 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0881289 |
| TMSB10 | thymosin beta 10 | -0.0880422 |
| HLA-B | major histocompatibility complex, class I, B | -0.0838303 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0815095 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0781556 |
| GPC6 | glypican 6 | -0.0773328 |
| HMCN1 | hemicentin 1 | -0.0675075 |
| S100A6 | S100 calcium binding protein A6 | -0.0592736 |
| FRMD4A | FERM domain containing 4A | -0.0576255 |
| DCT | dopachrome tautomerase | -0.0576181 |
| EHBP1 | EH domain binding protein 1 | -0.056864 |
| PTCHD4 | patched domain containing 4 | -0.0562688 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0556276 |
| GDF15 | growth differentiation factor 15 | -0.0538504 |
| NLGN1 | neuroligin 1 | -0.0530106 |
| MACROD2 | MACRO domain containing 2 | -0.0527368 |
| CALD1 | caldesmon 1 | -0.0525212 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0499847 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0465786 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0461309 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0448078 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0443427 |
| TNNC1 | troponin C type 1 (slow) | -0.0443422 |
| FRMD5 | FERM domain containing 5 | -0.0443317 |
| LAMB1 | laminin, beta 1 | -0.043596 |
| TAGLN2 | transgelin 2 | -0.042742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0421006 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0399832 |
| FTL | ferritin, light polypeptide | -0.0386546 |
| VGF | VGF nerve growth factor inducible | -0.0382101 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0379783 |
| SFTPA2 | surfactant protein A2 | -0.0377927 |
| NAV3 | neuron navigator 3 | -0.0363158 |
| S100A9 | S100 calcium binding protein A9 | -0.0358498 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0347144 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0329527 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0328611 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.032822 |
| RPS19 | ribosomal protein S19 | -0.0328044 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0327126 |
| MTPN | myotrophin | -0.0327005 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0324123 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0322315 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0321924 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321178 |
| PGK1 | phosphoglycerate kinase 1 | -0.0318794 |
| NHSL1 | NHS-like 1 | -0.0313917 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0313301 |
| CD63 | CD63 molecule | -0.0309967 |
| B2M | beta-2-microglobulin | -0.0306097 |
| PKM | pyruvate kinase, muscle | -0.0304196 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.029603 |
| A2M | alpha-2-macroglobulin | -0.0293924 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0291282 |
| GNAS | GNAS complex locus | -0.0291167 |
| TPI1 | triosephosphate isomerase 1 | -0.0289522 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0288067 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0287644 |
| POTEF | POTE ankyrin domain family, member F | -0.027964 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.027904 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.026888 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268528 |
| PCDH7 | protocadherin 7 | -0.0265115 |
| NRCAM | neuronal cell adhesion molecule | -0.0262884 |
| LSAMP | limbic system-associated membrane protein | -0.0262829 |
| SDC2 | syndecan 2 | -0.0256629 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0255303 |
| RPL37A | ribosomal protein L37a | -0.0249002 |
| CCND1 | cyclin D1 | -0.0247624 |
| TCF12 | transcription factor 12 | -0.0244972 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0242746 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0238077 |
| TRIM2 | tripartite motif containing 2 | -0.0237758 |
| OXR1 | oxidation resistance 1 | -0.0237032 |
| SEM1 | SEM1 26S proteasome subunit | -0.0234766 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0233465 |
| RPS6 | ribosomal protein S6 | -0.023143 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0228821 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0227707 |
| RPL35A | ribosomal protein L35a | -0.0227704 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0225147 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0224892 |
| SCFD2 | sec1 family domain containing 2 | -0.0224317 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0223662 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0223567 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0216851 |
| BBX | bobby sox homolog (Drosophila) | -0.0213967 |
| MITF | microphthalmia-associated transcription factor | -0.0211911 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0211109 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0210098 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.020877 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0208607 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | -0.0207148 |
