| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.139395 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.118778 |
| APOL1 | apolipoprotein L, 1 | 0.107828 |
| SMAD3 | SMAD family member 3 | 0.106042 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0858529 |
| AHNAK | AHNAK nucleoprotein | 0.0836499 |
| APP | amyloid beta (A4) precursor protein | 0.0803999 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0794539 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0667792 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0584665 |
| CP | ceruloplasmin (ferroxidase) | 0.0577526 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0551799 |
| RAD51B | RAD51 paralog B | 0.0524409 |
| SDC4 | syndecan 4 | 0.0503025 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0501157 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.048756 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0468547 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0450356 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.044316 |
| PLEC | plectin | 0.0409536 |
| TGM2 | transglutaminase 2 | 0.0387995 |
| XPO1 | exportin 1 | 0.0383263 |
| PKM | pyruvate kinase, muscle | 0.0372842 |
| AFAP1 | actin filament associated protein 1 | 0.0370325 |
| MCL1 | myeloid cell leukemia 1 | 0.036766 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0353634 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0349226 |
| ANXA4 | annexin A4 | 0.0336371 |
| KIAA1217 | KIAA1217 | 0.0332309 |
| ENO1 | enolase 1, (alpha) | 0.0332093 |
| APOL2 | apolipoprotein L, 2 | 0.0327024 |
| PFKP | phosphofructokinase, platelet | 0.0319434 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0315883 |
| ARRDC3 | arrestin domain containing 3 | 0.031194 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303588 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0273078 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0272957 |
| MYOF | myoferlin | 0.0271304 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0270508 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0268142 |
| ASPH | aspartate beta-hydroxylase | 0.0259425 |
| VEGFA | vascular endothelial growth factor A | 0.0258842 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0258688 |
| HDAC9 | histone deacetylase 9 | 0.0256689 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0251292 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245138 |
| RNASET2 | ribonuclease T2 | 0.0237752 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0237164 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0235714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023363 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0232479 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0230977 |
| STC2 | stanniocalcin 2 | 0.0230149 |
| CFB | complement factor B | 0.0227444 |
| CMIP | c-Maf inducing protein | 0.0226643 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0224239 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0219538 |
| C3 | complement component 3 | 0.0217827 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217801 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0216085 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0214423 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0207997 |
| PRELID2 | PRELI domain containing 2 | 0.0206641 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0205657 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0203395 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0201279 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0196666 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0196602 |
| FLNA | filamin A, alpha | 0.0195609 |
| TMEM51 | transmembrane protein 51 | 0.0195022 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0194819 |
| OGA | O-GlcNAcase | 0.0192681 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0191403 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0185975 |
| HLA-E | major histocompatibility complex, class I, E | 0.0184283 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0179612 |
| LCN2 | lipocalin 2 | 0.0178938 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0176636 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0176531 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0176482 |
| NABP1 | nucleic acid binding protein 1 | 0.0176264 |
| TPM3 | tropomyosin 3 | 0.0175745 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0175181 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0172067 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0170669 |
| WDR72 | WD repeat domain 72 | 0.0168821 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0168803 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0167686 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0164429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.016423 |
| BBX | bobby sox homolog (Drosophila) | 0.0163384 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.016067 |
| IGSF11 | immunoglobulin superfamily, member 11 | 0.0159825 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0158251 |
| ANO6 | anoctamin 6 | 0.0158073 |
| VMP1 | vacuole membrane protein 1 | 0.0157155 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0156423 |
| PHF21A | PHD finger protein 21A | 0.0156297 |
| BRD2 | bromodomain containing 2 | 0.0154415 |
| RNF150 | ring finger protein 150 | 0.0154238 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202308 |
| TMSB10 | thymosin beta 10 | -0.150572 |
| SPAG9 | sperm associated antigen 9 | -0.119888 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.116914 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.106725 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0901688 |
| MT1X | metallothionein 1X | -0.0885629 |
| ACTG1 | actin gamma 1 | -0.0857702 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0847555 |
| ANXA2 | annexin A2 | -0.0788269 |
| MT2A | metallothionein 2A | -0.0774019 |
| DTNA | dystrobrevin, alpha | -0.0769963 |
| RTN4 | reticulon 4 | -0.0750872 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0714567 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0705025 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0660011 |
| TJP1 | tight junction protein 1 | -0.0657058 |
| PLAU | plasminogen activator, urokinase | -0.0653489 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0591658 |
| HMGA1 | high mobility group AT-hook 1 | -0.0587995 |
| PTMA | prothymosin, alpha | -0.0556049 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0528899 |
| CD2AP | CD2-associated protein | -0.0526416 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0524776 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0499757 |
| FTL | ferritin, light polypeptide | -0.0499069 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0498037 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0494384 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0491511 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0490173 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0489728 |
| BICC1 | BicC family RNA binding protein 1 | -0.0486078 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0475014 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0466278 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0466262 |
| RCOR1 | REST corepressor 1 | -0.0449074 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0446838 |
| OSMR | oncostatin M receptor | -0.0446537 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0441336 |
| MAP1B | microtubule-associated protein 1B | -0.0428349 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0408932 |
| MCU | mitochondrial calcium uniporter | -0.0405705 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0402885 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0398712 |
| LAMB3 | laminin, beta 3 | -0.0390413 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.038917 |
| RPL19 | ribosomal protein L19 | -0.0388588 |
| RBM25 | RNA binding motif protein 25 | -0.0385459 |
| MORF4L2 | mortality factor 4 like 2 | -0.0384707 |
| RPL35A | ribosomal protein L35a | -0.0383956 |
| PGK1 | phosphoglycerate kinase 1 | -0.0382141 |
| RASA2 | RAS p21 protein activator 2 | -0.0380224 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0379796 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.037508 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0370628 |
| RPLP1 | ribosomal protein, large, P1 | -0.0369208 |
| RRBP1 | ribosome binding protein 1 | -0.0367885 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0358773 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0358015 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0355865 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0352629 |
| RBM39 | RNA binding motif protein 39 | -0.0349915 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0348333 |
| RPL11 | ribosomal protein L11 | -0.0345505 |
| NEK7 | NIMA-related kinase 7 | -0.0342411 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0339927 |
| KLF6 | Kruppel-like factor 6 | -0.0335199 |
| RASAL2 | RAS protein activator like 2 | -0.0334973 |
| SEC24A | SEC24 family member A | -0.0333268 |
| DSG2 | desmoglein 2 | -0.0333138 |
| RPS6 | ribosomal protein S6 | -0.0332101 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0330038 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0328727 |
| TOP1 | topoisomerase (DNA) I | -0.0326001 |
| FOXO3 | forkhead box O3 | -0.0324996 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0323742 |
| LAMA4 | laminin, alpha 4 | -0.0321933 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.031675 |
| B2M | beta-2-microglobulin | -0.031435 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0310773 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0309758 |
| GOLGA4 | golgin A4 | -0.0303543 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0301016 |
| VIM | vimentin | -0.0298807 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.029849 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0296586 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0296309 |
| HLA-B | major histocompatibility complex, class I, B | -0.0296231 |
| TFG | TRK-fused gene | -0.0293223 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.029248 |
| S100A6 | S100 calcium binding protein A6 | -0.0291934 |
| CDC73 | cell division cycle 73 | -0.029138 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290595 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0289663 |
| LMO7 | LIM domain 7 | -0.0289138 |
| SP100 | SP100 nuclear antigen | -0.0288901 |
| RLF | rearranged L-myc fusion | -0.0286503 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0285212 |
| USP15 | ubiquitin specific peptidase 15 | -0.0282831 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0282705 |
