| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.133897 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0920125 |
| FAM13A | family with sequence similarity 13, member A | 0.0883405 |
| NDRG1 | N-myc downstream regulated 1 | 0.0881827 |
| HDAC9 | histone deacetylase 9 | 0.0730276 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0716132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0614286 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0503401 |
| XPO1 | exportin 1 | 0.0491553 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.047142 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0465548 |
| OGA | O-GlcNAcase | 0.0461194 |
| COL5A1 | collagen, type V, alpha 1 | 0.0457327 |
| VEGFA | vascular endothelial growth factor A | 0.0432505 |
| FNIP1 | folliculin interacting protein 1 | 0.0389892 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0386759 |
| LOX | lysyl oxidase | 0.0376337 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0373827 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0366496 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0364368 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0335085 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0328935 |
| GOLGA4 | golgin A4 | 0.0323341 |
| ARRDC3 | arrestin domain containing 3 | 0.0311616 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0310623 |
| MMP12 | matrix metallopeptidase 12 | 0.0302022 |
| HELZ | helicase with zinc finger | 0.0300114 |
| ZNF160 | zinc finger protein 160 | 0.0284935 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0283212 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0273854 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0270167 |
| COPA | coatomer protein complex, subunit alpha | 0.0266213 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0265352 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0262973 |
| RNF150 | ring finger protein 150 | 0.0262145 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0259877 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0258549 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0257981 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0256943 |
| PRELID2 | PRELI domain containing 2 | 0.0255995 |
| YEATS2 | YEATS domain containing 2 | 0.0253269 |
| RLIM | ring finger protein, LIM domain interacting | 0.0249067 |
| SRP54 | signal recognition particle 54kDa | 0.0247016 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0242593 |
| MYOF | myoferlin | 0.0232993 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0231233 |
| NUP58 | nucleoporin 58 | 0.0230223 |
| CCNG2 | cyclin G2 | 0.0229846 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0229424 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0227571 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0222904 |
| CD47 | CD47 molecule | 0.0222539 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0220459 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0220089 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0216687 |
| ZNF841 | zinc finger protein 841 | 0.0216476 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0216116 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0215812 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0215735 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0211694 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.021016 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.020884 |
| INSIG2 | insulin induced gene 2 | 0.0203332 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0202704 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0200752 |
| CCNL1 | cyclin L1 | 0.0200359 |
| RNF24 | ring finger protein 24 | 0.0194819 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0192162 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0191096 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.018631 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0185504 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0184863 |
| MYO1B | myosin IB | 0.0181173 |
| DTNA | dystrobrevin, alpha | 0.0181153 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0180314 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0177085 |
| TMF1 | TATA element modulatory factor 1 | 0.0176625 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0175104 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0174331 |
| ZNF292 | zinc finger protein 292 | 0.0172519 |
| ATM | ATM serine/threonine kinase | 0.0170635 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0169567 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0168555 |
| SMAD3 | SMAD family member 3 | 0.0168501 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.016744 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0167143 |
| SEC24A | SEC24 family member A | 0.0166452 |
| NGLY1 | N-glycanase 1 | 0.0165726 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0162874 |
| BRD2 | bromodomain containing 2 | 0.0162575 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0162565 |
| DENND4C | DENN/MADD domain containing 4C | 0.0162126 |
| JUN | jun proto-oncogene | 0.0162048 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0161664 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0160401 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0158628 |
| CD109 | CD109 molecule | 0.0157723 |
| TBCK | TBC1 domain containing kinase | 0.0157588 |
| STK32A | serine/threonine kinase 32A | 0.0157195 |
| NCOR2 | nuclear receptor corepressor 2 | 0.015382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.212856 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16653 |
| FTL | ferritin, light polypeptide | -0.155449 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112785 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102017 |
| VIM | vimentin | -0.0926719 |
| MT2A | metallothionein 2A | -0.0902287 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0888185 |
| PTMA | prothymosin, alpha | -0.0759853 |
| CD44 | CD44 molecule (Indian blood group) | -0.075098 |
| HLA-B | major histocompatibility complex, class I, B | -0.0747066 |
| RPS6 | ribosomal protein S6 | -0.0711811 |
| TPM4 | tropomyosin 4 | -0.0656395 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0655757 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0626963 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0610356 |
| B2M | beta-2-microglobulin | -0.060392 |
| RPS8 | ribosomal protein S8 | -0.059801 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0589212 |
| DST | dystonin | -0.0577576 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0546112 |
| RPLP1 | ribosomal protein, large, P1 | -0.0540877 |
| RPS19 | ribosomal protein S19 | -0.0527476 |
| PTCHD4 | patched domain containing 4 | -0.0516955 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0514438 |
| RPL35A | ribosomal protein L35a | -0.0499255 |
| GLIS3 | GLIS family zinc finger 3 | -0.0489684 |
| STK17A | serine/threonine kinase 17a | -0.045617 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0448802 |
| RPL23 | ribosomal protein L23 | -0.0445966 |
| TPI1 | triosephosphate isomerase 1 | -0.0439849 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0436337 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0433931 |
| MAP1B | microtubule-associated protein 1B | -0.0423067 |
| RPL28 | ribosomal protein L28 | -0.0421973 |
| ACTG1 | actin gamma 1 | -0.0420149 |
| SBF2 | SET binding factor 2 | -0.0412354 |
| POTEF | POTE ankyrin domain family, member F | -0.0408621 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0408358 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0407125 |
| RPLP2 | ribosomal protein, large, P2 | -0.0400785 |
| AHNAK | AHNAK nucleoprotein | -0.040053 |
| RPL34 | ribosomal protein L34 | -0.0393186 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0391027 |
| RPS3 | ribosomal protein S3 | -0.0385695 |
| NAV3 | neuron navigator 3 | -0.0383011 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0369681 |
| PGK1 | phosphoglycerate kinase 1 | -0.0361915 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.035523 |
| ENO1 | enolase 1, (alpha) | -0.0352841 |
| RPS24 | ribosomal protein S24 | -0.0352329 |
| ATXN1 | ataxin 1 | -0.0350714 |
| RPL37A | ribosomal protein L37a | -0.0350475 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0350039 |
| TNNC1 | troponin C type 1 (slow) | -0.0346723 |
| MT1X | metallothionein 1X | -0.0346313 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0344239 |
| GNAS | GNAS complex locus | -0.0342075 |
| S100A6 | S100 calcium binding protein A6 | -0.0340145 |
| S100A10 | S100 calcium binding protein A10 | -0.033654 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.033075 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0328298 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0325887 |
| RPS13 | ribosomal protein S13 | -0.0325721 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0323664 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0318552 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0316926 |
| CDK6 | cyclin-dependent kinase 6 | -0.0315778 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0312367 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0311872 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0305362 |
| RPL27A | ribosomal protein L27a | -0.0303592 |
| RNF216 | ring finger protein 216 | -0.0300293 |
| STC1 | stanniocalcin 1 | -0.0299902 |
| INHBA | inhibin, beta A | -0.0299519 |
| RPL11 | ribosomal protein L11 | -0.0299199 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0299153 |
| VCL | vinculin | -0.0297982 |
| CBX3 | chromobox homolog 3 | -0.0297792 |
| RTN4 | reticulon 4 | -0.0296279 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0295394 |
| TMSB4X | thymosin beta 4, X-linked | -0.0292873 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0292291 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0290793 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0289338 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0285918 |
| S100A9 | S100 calcium binding protein A9 | -0.028288 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0281766 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0280433 |
| RPS11 | ribosomal protein S11 | -0.0276269 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0274779 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0274776 |
| PKM | pyruvate kinase, muscle | -0.0274102 |
| RPL9 | ribosomal protein L9 | -0.0271571 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0269012 |
| RPL31 | ribosomal protein L31 | -0.0268904 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0268553 |
| CLMP | CXADR-like membrane protein | -0.0266217 |
| RPL37 | ribosomal protein L37 | -0.0265895 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0265587 |
