| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.150066 |
| HMGA2 | high mobility group AT-hook 2 | 0.110187 |
| COL5A1 | collagen, type V, alpha 1 | 0.0986213 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0894912 |
| VIM | vimentin | 0.0830426 |
| AHNAK | AHNAK nucleoprotein | 0.0768008 |
| CD44 | CD44 molecule (Indian blood group) | 0.0582651 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.056282 |
| SEPTIN9 | septin 9 | 0.0441825 |
| CCND1 | cyclin D1 | 0.0415986 |
| XPO1 | exportin 1 | 0.0415701 |
| IGF2 | insulin-like growth factor 2 | 0.0401185 |
| LOX | lysyl oxidase | 0.0383266 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0369821 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0352154 |
| VMP1 | vacuole membrane protein 1 | 0.0288395 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0267451 |
| THBS2 | thrombospondin 2 | 0.0266512 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0263871 |
| GPC5 | glypican 5 | 0.026329 |
| ASPH | aspartate beta-hydroxylase | 0.0261956 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.025638 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0254276 |
| GLIS3 | GLIS family zinc finger 3 | 0.0222391 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0221544 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0216022 |
| ANXA2 | annexin A2 | 0.02117 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0208602 |
| FAT1 | FAT atypical cadherin 1 | 0.0203715 |
| MLPH | melanophilin | 0.0201058 |
| SMAD3 | SMAD family member 3 | 0.0199863 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0192132 |
| EMP1 | epithelial membrane protein 1 | 0.0188981 |
| CEP112 | centrosomal protein 112kDa | 0.0187065 |
| TPM4 | tropomyosin 4 | 0.0186583 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0185174 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.018508 |
| PLEC | plectin | 0.0183728 |
| CTSB | cathepsin B | 0.0182655 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0176985 |
| JAG1 | jagged 1 | 0.0176252 |
| PRSS23 | protease, serine, 23 | 0.0174173 |
| RNF150 | ring finger protein 150 | 0.0167483 |
| EXT1 | exostosin glycosyltransferase 1 | 0.016438 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0160817 |
| IL11 | interleukin 11 | 0.0158152 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0157701 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0157552 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0156849 |
| HLA-E | major histocompatibility complex, class I, E | 0.0156504 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0156264 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0153274 |
| RND3 | Rho family GTPase 3 | 0.0152855 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0152447 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0151186 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0150906 |
| ARRDC3 | arrestin domain containing 3 | 0.0146254 |
| ENOSF1 | enolase superfamily member 1 | 0.0145216 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0143232 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0142222 |
| PODXL | podocalyxin-like | 0.0141445 |
| SDC4 | syndecan 4 | 0.0138057 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.013752 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0136955 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.0134997 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.0131848 |
| MT1E | metallothionein 1E | 0.0128701 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0128048 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0126851 |
| KYNU | kynureninase | 0.0124235 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0123911 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0123223 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0123104 |
| DNMBP | dynamin binding protein | 0.0122249 |
| CDK6 | cyclin-dependent kinase 6 | 0.0119791 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.0119623 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0119578 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.011642 |
| SSH2 | slingshot protein phosphatase 2 | 0.0115223 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0115111 |
| AUTS2 | autism susceptibility candidate 2 | 0.0113953 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0113095 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0111695 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0110763 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0110261 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.010891 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0108566 |
| EVC | Ellis van Creveld protein | 0.0108236 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0107894 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0106692 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0106168 |
| TUSC3 | tumor suppressor candidate 3 | 0.0105171 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0103818 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0102375 |
| NEK10 | NIMA-related kinase 10 | 0.0102324 |
| COL5A3 | collagen, type V, alpha 3 | 0.0102237 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0100942 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.00986835 |
| SYAP1 | synapse associated protein 1 | 0.00983062 |
| NINL | ninein-like | 0.00979613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.184537 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.126521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.122919 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.103952 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0988774 |
| TMSB10 | thymosin beta 10 | -0.0977117 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0971626 |
| ANKRD12 | ankyrin repeat domain 12 | -0.095805 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0912456 |
| PTMA | prothymosin, alpha | -0.0751781 |
| MT2A | metallothionein 2A | -0.0750931 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0730846 |
| RUNX1 | runt-related transcription factor 1 | -0.0725497 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0714194 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0713289 |
| NDRG1 | N-myc downstream regulated 1 | -0.0713189 |
| DTNA | dystrobrevin, alpha | -0.0685223 |
| FAM13A | family with sequence similarity 13, member A | -0.068471 |
| SPAG9 | sperm associated antigen 9 | -0.0673541 |
| GOLGA4 | golgin A4 | -0.0655258 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0653749 |
| NAV2 | neuron navigator 2 | -0.0631589 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0613731 |
| SBF2 | SET binding factor 2 | -0.0608956 |
| ZNF292 | zinc finger protein 292 | -0.0607879 |
| RPS6 | ribosomal protein S6 | -0.0597106 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0581036 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0574978 |
| SETD5 | SET domain containing 5 | -0.0563297 |
| CDH13 | cadherin 13 | -0.0547843 |
| DIAPH2 | diaphanous-related formin 2 | -0.0532534 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0513938 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.051181 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0511386 |
| CENPF | centromere protein F, 350/400kDa | -0.0505582 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0493121 |
| PRELID2 | PRELI domain containing 2 | -0.0479617 |
| USP34 | ubiquitin specific peptidase 34 | -0.0472864 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0468483 |
| FLNB | filamin B, beta | -0.0464157 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0456773 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0456532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0453239 |
| RRBP1 | ribosome binding protein 1 | -0.0452416 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0452298 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0443878 |
| RBM39 | RNA binding motif protein 39 | -0.0443541 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0439115 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0429474 |
| HELZ | helicase with zinc finger | -0.0425473 |
| PDE10A | phosphodiesterase 10A | -0.0424378 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0424231 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0414383 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0401586 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.039563 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0395604 |
| RTN4 | reticulon 4 | -0.0386471 |
| ADM | adrenomedullin | -0.0381639 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0373984 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0371707 |
| NBAS | neuroblastoma amplified sequence | -0.0369831 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0368728 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0367125 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0366163 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0361375 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0361193 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0360738 |
| CLTC | clathrin, heavy chain (Hc) | -0.0360579 |
| NGLY1 | N-glycanase 1 | -0.0359471 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0357397 |
| SEC24D | SEC24 family member D | -0.0353172 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0349808 |
| NF1 | neurofibromin 1 | -0.0348849 |
| ATXN1 | ataxin 1 | -0.0348435 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0340179 |
| NKTR | natural killer cell triggering receptor | -0.0340144 |
| PTK2 | protein tyrosine kinase 2 | -0.034002 |
| VCL | vinculin | -0.0338746 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0338162 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0336757 |
| SEC24A | SEC24 family member A | -0.0335347 |
| SEPTIN2 | septin 2 | -0.0335208 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0331429 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0329198 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0329035 |
| RPL11 | ribosomal protein L11 | -0.0328624 |
| MSN | moesin | -0.0328208 |
| RRM2 | ribonucleotide reductase M2 | -0.0324896 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0320191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0320091 |
| CD109 | CD109 molecule | -0.0319529 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0318431 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0318054 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.031676 |
| COG5 | component of oligomeric golgi complex 5 | -0.0315913 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0315674 |
| TPX2 | TPX2, microtubule-associated | -0.0314825 |
| FMN1 | formin 1 | -0.0314638 |
| RPL23 | ribosomal protein L23 | -0.0314471 |
| COPA | coatomer protein complex, subunit alpha | -0.0309567 |
