| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.120961 |
| COL6A3 | collagen, type VI, alpha 3 | 0.081691 |
| CDH13 | cadherin 13 | 0.0810887 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0765467 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0597117 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0531403 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0450688 |
| VMP1 | vacuole membrane protein 1 | 0.0428992 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0423523 |
| PDE10A | phosphodiesterase 10A | 0.0357775 |
| RND3 | Rho family GTPase 3 | 0.0352003 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.033054 |
| HDAC9 | histone deacetylase 9 | 0.0329477 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.031716 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306284 |
| COL5A1 | collagen, type V, alpha 1 | 0.0297113 |
| VEGFA | vascular endothelial growth factor A | 0.0267055 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0264185 |
| XPO1 | exportin 1 | 0.0256666 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0248885 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0234921 |
| RNF150 | ring finger protein 150 | 0.0215463 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0204905 |
| UST | uronyl-2-sulfotransferase | 0.0201565 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0201469 |
| PTK2 | protein tyrosine kinase 2 | 0.0197911 |
| EGFR | epidermal growth factor receptor | 0.0190816 |
| FAT1 | FAT atypical cadherin 1 | 0.018197 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0178052 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.017717 |
| NAV2 | neuron navigator 2 | 0.0175869 |
| BRD2 | bromodomain containing 2 | 0.0170501 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0165424 |
| NOTCH2 | notch 2 | 0.0154837 |
| FNIP1 | folliculin interacting protein 1 | 0.0154301 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0149504 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0141472 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.013691 |
| INTS6 | integrator complex subunit 6 | 0.0133952 |
| CMIP | c-Maf inducing protein | 0.0129582 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0128866 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0127507 |
| ARRDC3 | arrestin domain containing 3 | 0.0124878 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0124651 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0122788 |
| TNS1 | tensin 1 | 0.0122695 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0121995 |
| JMJD1C | jumonji domain containing 1C | 0.0121155 |
| EXOC4 | exocyst complex component 4 | 0.0121009 |
| DIPK2A | divergent protein kinase domain 2A | 0.0118635 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0117419 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0115366 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0115128 |
| FMNL2 | formin-like 2 | 0.0114739 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0112378 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0111053 |
| SQSTM1 | sequestosome 1 | 0.0109641 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0105283 |
| EFNA5 | ephrin-A5 | 0.010376 |
| MSN | moesin | 0.0102829 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0102323 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0102263 |
| HMGA2 | high mobility group AT-hook 2 | 0.0102243 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.010089 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0100832 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 0.0100689 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00988088 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0098551 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.00978596 |
| ANO10 | anoctamin 10 | 0.00966266 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.00960942 |
| GLIS3 | GLIS family zinc finger 3 | 0.00956394 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00955621 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00955261 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.00948708 |
| NEK10 | NIMA-related kinase 10 | 0.00938557 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.00913504 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0091079 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.00886326 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00884931 |
| SEPTIN9 | septin 9 | 0.00865668 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00859215 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0085911 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00858904 |
| NLRP1 | NLR family, pyrin domain containing 1 | 0.00853795 |
| EBF1 | early B-cell factor 1 | 0.00838237 |
| KIAA1549L | KIAA1549-like | 0.00830799 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00830378 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00828876 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00817833 |
| OGA | O-GlcNAcase | 0.0081178 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00809445 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00800764 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.00799351 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0079505 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00790953 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.00784419 |
| ANXA1 | annexin A1 | 0.00776408 |
| RUNX1 | runt-related transcription factor 1 | 0.00775367 |
| GPHN | gephyrin | 0.00773379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.235223 |
| MT2A | metallothionein 2A | -0.193324 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182432 |
| VIM | vimentin | -0.147496 |
| FN1 | fibronectin 1 | -0.141082 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.127002 |
| COL1A1 | collagen, type I, alpha 1 | -0.120982 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.116024 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0997984 |
| TMSB10 | thymosin beta 10 | -0.0924398 |
| INHBA | inhibin, beta A | -0.0913332 |
| CD44 | CD44 molecule (Indian blood group) | -0.0898891 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0728905 |
| ENO1 | enolase 1, (alpha) | -0.072169 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0714488 |
| COL1A2 | collagen, type I, alpha 2 | -0.0708599 |
| IER3 | immediate early response 3 | -0.0688319 |
| MT1X | metallothionein 1X | -0.0616097 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0586409 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0585794 |
| STC1 | stanniocalcin 1 | -0.0539612 |
| UBC | ubiquitin C | -0.0524277 |
| LDHA | lactate dehydrogenase A | -0.051783 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0517273 |
| ADM | adrenomedullin | -0.0515807 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0445617 |
| FTL | ferritin, light polypeptide | -0.0425662 |
| B2M | beta-2-microglobulin | -0.0425621 |
| LOX | lysyl oxidase | -0.0421358 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0400438 |
| ACTG1 | actin gamma 1 | -0.0388442 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0382722 |
| PTMA | prothymosin, alpha | -0.0375191 |
| ATP13A3 | ATPase type 13A3 | -0.037304 |
| RPS8 | ribosomal protein S8 | -0.0358832 |
| CALR | calreticulin | -0.0358218 |
| TPM4 | tropomyosin 4 | -0.035554 |
| RPL11 | ribosomal protein L11 | -0.035117 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0349968 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.03463 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0344086 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0339175 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0333644 |
| CANX | calnexin | -0.0333392 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330806 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0327538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0323065 |
| CALU | calumenin | -0.0322612 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0308335 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0301776 |
| RPL23 | ribosomal protein L23 | -0.0285716 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0273709 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0267522 |
| PGK1 | phosphoglycerate kinase 1 | -0.0265881 |
| S100A6 | S100 calcium binding protein A6 | -0.0262848 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0262091 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0261066 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0259133 |
| GOLGA4 | golgin A4 | -0.0258689 |
| RRBP1 | ribosome binding protein 1 | -0.0257829 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0253933 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0253674 |
| IL6 | interleukin 6 | -0.0249429 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248225 |
| RPL26 | ribosomal protein L26 | -0.0242912 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0241829 |
| MTSS1 | metastasis suppressor 1 | -0.0241634 |
| OSMR | oncostatin M receptor | -0.0237142 |
| CLIC4 | chloride intracellular channel 4 | -0.0235614 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0235175 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0232438 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0231969 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0231762 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0231272 |
| PKM | pyruvate kinase, muscle | -0.0230736 |
| RPS27A | ribosomal protein S27a | -0.0229571 |
| S100A9 | S100 calcium binding protein A9 | -0.022635 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0225002 |
| TPI1 | triosephosphate isomerase 1 | -0.0223546 |
| SBF2 | SET binding factor 2 | -0.0223535 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0223412 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0221674 |
| PRELID2 | PRELI domain containing 2 | -0.0219295 |
| RPL35A | ribosomal protein L35a | -0.0217157 |
| RPS19 | ribosomal protein S19 | -0.0214906 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0214183 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0211449 |
| RPS6 | ribosomal protein S6 | -0.0211115 |
| RPL34 | ribosomal protein L34 | -0.0210933 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0209383 |
| SPAG9 | sperm associated antigen 9 | -0.0208751 |
| RACK1 | receptor for activated C kinase 1 | -0.0206712 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0205433 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0204175 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0203984 |
| RPS3 | ribosomal protein S3 | -0.0202307 |
| BBX | bobby sox homolog (Drosophila) | -0.0201625 |
| RPL19 | ribosomal protein L19 | -0.0196827 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0195339 |
| POSTN | periostin, osteoblast specific factor | -0.019482 |
