| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.0738903 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0566728 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0468881 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0304288 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.030378 |
| FN1 | fibronectin 1 | 0.0284791 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0266922 |
| XPO1 | exportin 1 | 0.0252387 |
| DSPP | dentin sialophosphoprotein | 0.0235446 |
| VMP1 | vacuole membrane protein 1 | 0.0233841 |
| PTCHD4 | patched domain containing 4 | 0.0230173 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0211297 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0201958 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0195001 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0187962 |
| TNS3 | tensin 3 | 0.018677 |
| BCL2L1 | BCL2-like 1 | 0.0186757 |
| FAT1 | FAT atypical cadherin 1 | 0.0184413 |
| SMAD3 | SMAD family member 3 | 0.0183813 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0183744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0179583 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0178034 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0176396 |
| CNKSR3 | CNKSR family member 3 | 0.0175818 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0169837 |
| TNS1 | tensin 1 | 0.016911 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0167504 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0166118 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0165143 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0155396 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0154014 |
| PRKCA | protein kinase C, alpha | 0.0153732 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0152691 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.014496 |
| INTS6 | integrator complex subunit 6 | 0.0142879 |
| AHNAK | AHNAK nucleoprotein | 0.01419 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0140539 |
| PDLIM5 | PDZ and LIM domain 5 | 0.01398 |
| FAM107B | family with sequence similarity 107, member B | 0.0138462 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0138425 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0138177 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0138163 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0137516 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0137449 |
| PLEC | plectin | 0.0136258 |
| SEPTIN9 | septin 9 | 0.0133743 |
| NHSL1 | NHS-like 1 | 0.0133103 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0129666 |
| TUFT1 | tuftelin 1 | 0.0128608 |
| JAG1 | jagged 1 | 0.0127768 |
| FMNL2 | formin-like 2 | 0.0123514 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0122243 |
| FLNA | filamin A, alpha | 0.0121025 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0120974 |
| ACVR1 | activin A receptor, type I | 0.0120835 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0117885 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0117152 |
| OGA | O-GlcNAcase | 0.0115366 |
| HPCAL1 | hippocalcin-like 1 | 0.0115211 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.011514 |
| AOPEP | aminopeptidase O (putative) | 0.0113778 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0112437 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0111905 |
| FOXP1 | forkhead box P1 | 0.0108689 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0102628 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00986144 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00986107 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.009796 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.00965737 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.00960039 |
| ANGPTL2 | angiopoietin-like 2 | 0.00956355 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.00952989 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.00951955 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | 0.0094856 |
| XPO6 | exportin 6 | 0.00929792 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00909074 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.00896692 |
| AHR | aryl hydrocarbon receptor | 0.00892123 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.00884814 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.00884589 |
| RUNX1 | runt-related transcription factor 1 | 0.00882326 |
| WDR27 | WD repeat domain 27 | 0.00877021 |
| SMYD3 | SET and MYND domain containing 3 | 0.00876233 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00873527 |
| SKI | SKI proto-oncogene | 0.0086248 |
| FAM120B | family with sequence similarity 120B | 0.00851103 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00850486 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0084481 |
| VCL | vinculin | 0.00842299 |
| PRTG | protogenin | 0.00840191 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00838182 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00836985 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0082538 |
| FRMD5 | FERM domain containing 5 | 0.00823347 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.00813079 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.00808928 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.00806742 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00805713 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00782248 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0078165 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.337207 |
| MT2A | metallothionein 2A | -0.190936 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.153676 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.150132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119721 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.113115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112636 |
| RPS6 | ribosomal protein S6 | -0.10381 |
| IGF2 | insulin-like growth factor 2 | -0.0944977 |
| APOA2 | apolipoprotein A-II | -0.0896412 |
| ENO1 | enolase 1, (alpha) | -0.089415 |
| RPL11 | ribosomal protein L11 | -0.0830197 |
| C3 | complement component 3 | -0.0796366 |
| FTL | ferritin, light polypeptide | -0.0785794 |
| RPS12 | ribosomal protein S12 | -0.0690762 |
| APOB | apolipoprotein B | -0.067852 |
| RPS8 | ribosomal protein S8 | -0.0678291 |
| RPL37A | ribosomal protein L37a | -0.0668466 |
| AHSG | alpha-2-HS-glycoprotein | -0.0652567 |
| GPC3 | glypican 3 | -0.0624882 |
| TMSB10 | thymosin beta 10 | -0.0592487 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.058936 |
| RPS24 | ribosomal protein S24 | -0.0584456 |
| RPLP1 | ribosomal protein, large, P1 | -0.0576011 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0571318 |
| RPS19 | ribosomal protein S19 | -0.0566036 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0558673 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0542049 |
| RPL35A | ribosomal protein L35a | -0.0508828 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0505596 |
| RPLP0 | ribosomal protein, large, P0 | -0.0505293 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0505199 |
| RPL34 | ribosomal protein L34 | -0.0501265 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0480837 |
| RPL23 | ribosomal protein L23 | -0.0471612 |
| RPL31 | ribosomal protein L31 | -0.0470412 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0456469 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0445841 |
| RPL12 | ribosomal protein L12 | -0.0437247 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0416042 |
| HMGA1 | high mobility group AT-hook 1 | -0.0405191 |
| RPLP2 | ribosomal protein, large, P2 | -0.0402554 |
| RPS27A | ribosomal protein S27a | -0.0395542 |
| RPL9 | ribosomal protein L9 | -0.0395318 |
| RPL26 | ribosomal protein L26 | -0.0394955 |
| RPS21 | ribosomal protein S21 | -0.0392375 |
| APOE | apolipoprotein E | -0.0391291 |
| NDRG1 | N-myc downstream regulated 1 | -0.0385354 |
| RACK1 | receptor for activated C kinase 1 | -0.0383109 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0381328 |
| RPS3 | ribosomal protein S3 | -0.0377374 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0374872 |
| PTMA | prothymosin, alpha | -0.0359267 |
| RPS13 | ribosomal protein S13 | -0.0347594 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0344053 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0342052 |
| RPS23 | ribosomal protein S23 | -0.0340844 |
| GOLGA4 | golgin A4 | -0.0331472 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0331188 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329498 |
| RPS14 | ribosomal protein S14 | -0.0324639 |
| APOA1 | apolipoprotein A-I | -0.0322521 |
| GNAS | GNAS complex locus | -0.0320621 |
| RPL5 | ribosomal protein L5 | -0.0318705 |
| B2M | beta-2-microglobulin | -0.0317242 |
| RPL19 | ribosomal protein L19 | -0.0314753 |
| RPS29 | ribosomal protein S29 | -0.0312783 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0312768 |
| RPS25 | ribosomal protein S25 | -0.0304971 |
| CPE | carboxypeptidase E | -0.0297465 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0296298 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293498 |
| TRIM26 | tripartite motif containing 26 | -0.0291862 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0290769 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0288401 |
| RPS5 | ribosomal protein S5 | -0.0283074 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.027754 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0277094 |
| RPL8 | ribosomal protein L8 | -0.0271583 |
| S100A9 | S100 calcium binding protein A9 | -0.0270108 |
| RPL32 | ribosomal protein L32 | -0.0268882 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0268608 |
| RPL37 | ribosomal protein L37 | -0.0265284 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0261815 |
| RPS16 | ribosomal protein S16 | -0.0261267 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.025854 |
| UBC | ubiquitin C | -0.0258039 |
| RPL10A | ribosomal protein L10a | -0.0255729 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0255245 |
| RPS17 | ribosomal protein S17 | -0.0252604 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0251673 |
| PRRC2C | proline-rich coiled-coil 2C | -0.025011 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250014 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0247649 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0247176 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0244944 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0238892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0238334 |
| RPL28 | ribosomal protein L28 | -0.0237254 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0232024 |
