| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Selinexor _J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0813975 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0587908 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0500762 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0499586 |
| MSN | moesin | 0.0483851 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0433108 |
| NDRG1 | N-myc downstream regulated 1 | 0.0428215 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0427751 |
| TLE4 | transducin-like enhancer of split 4 | 0.034021 |
| POTEF | POTE ankyrin domain family, member F | 0.0328893 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0324745 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0319921 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0315158 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0312596 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0279483 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265815 |
| FOSL1 | FOS-like antigen 1 | 0.0264833 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0260926 |
| SDC4 | syndecan 4 | 0.026008 |
| PTK2 | protein tyrosine kinase 2 | 0.0259522 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.025826 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0255407 |
| INTS6 | integrator complex subunit 6 | 0.0254206 |
| FLNA | filamin A, alpha | 0.0253415 |
| VEGFA | vascular endothelial growth factor A | 0.0253179 |
| NAV2 | neuron navigator 2 | 0.0250391 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0249974 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0249689 |
| CALD1 | caldesmon 1 | 0.0249202 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0247518 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0241178 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0232342 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0232306 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0226753 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0222591 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0221686 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0219081 |
| ZNF432 | zinc finger protein 432 | 0.0215551 |
| XPO1 | exportin 1 | 0.0213242 |
| FHIT | fragile histidine triad | 0.0213172 |
| RNF150 | ring finger protein 150 | 0.0212426 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0210464 |
| ZNF841 | zinc finger protein 841 | 0.0210374 |
| MMP12 | matrix metallopeptidase 12 | 0.0205031 |
| ANXA1 | annexin A1 | 0.0203546 |
| TUFT1 | tuftelin 1 | 0.0203541 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0203229 |
| ADM | adrenomedullin | 0.0200917 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0193349 |
| TFRC | transferrin receptor | 0.0192421 |
| WWOX | WW domain containing oxidoreductase | 0.0190655 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.018981 |
| TPM1 | tropomyosin 1 (alpha) | 0.0185742 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 | 0.018404 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0181043 |
| MYO10 | myosin X | 0.018092 |
| EXOC4 | exocyst complex component 4 | 0.0179717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0179428 |
| MECOM | MDS1 and EVI1 complex locus | 0.0177731 |
| DTNA | dystrobrevin, alpha | 0.0177481 |
| ARRDC3 | arrestin domain containing 3 | 0.0176525 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.017505 |
| KLF10 | Kruppel-like factor 10 | 0.0174334 |
| CFAP20DC | CFAP20 domain containing | 0.017356 |
| CCDC80 | coiled-coil domain containing 80 | 0.0171138 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0169716 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0168498 |
| PRKCA | protein kinase C, alpha | 0.0167347 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0166583 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.016653 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0165552 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0164422 |
| MAP1B | microtubule-associated protein 1B | 0.0163564 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0163189 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0161861 |
| PCBP2 | poly(rC) binding protein 2 | 0.0160519 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0160161 |
| CNTLN | centlein, centrosomal protein | 0.0160004 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0159881 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0157278 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0157271 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0154593 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0153144 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0150329 |
| APP | amyloid beta (A4) precursor protein | 0.0150324 |
| NHSL1 | NHS-like 1 | 0.014899 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0148563 |
| JUN | jun proto-oncogene | 0.0148396 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0147996 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0146674 |
| MED13 | mediator complex subunit 13 | 0.0146342 |
| ABHD3 | abhydrolase domain containing 3 | 0.0146144 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0145961 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0144226 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.0143883 |
| FAM13A | family with sequence similarity 13, member A | 0.0143378 |
| FUS | FUS RNA binding protein | 0.0142147 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0141834 |
| SET | SET nuclear proto-oncogene | 0.0141213 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0140378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18677 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.17334 |
| HLA-B | major histocompatibility complex, class I, B | -0.128369 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.120741 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.101333 |
| FTL | ferritin, light polypeptide | -0.0979773 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0975117 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0961547 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.07874 |
| ATP13A3 | ATPase type 13A3 | -0.0724058 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0660916 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0640926 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0595977 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0561309 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0546522 |
| GOLGA4 | golgin A4 | -0.0527073 |
| GLIS3 | GLIS family zinc finger 3 | -0.0482316 |
| OSMR | oncostatin M receptor | -0.0464453 |
| CD44 | CD44 molecule (Indian blood group) | -0.0406678 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0396801 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0389443 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0389049 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0386974 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0384989 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0377155 |
| ENO1 | enolase 1, (alpha) | -0.0372191 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0371876 |
| PGK1 | phosphoglycerate kinase 1 | -0.0371496 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0371015 |
| GRAMD2B | GRAM domain containing 2B | -0.0369137 |
| IL6ST | interleukin 6 signal transducer | -0.036896 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0349242 |
| ERBIN | erbb2 interacting protein | -0.0345877 |
| CANX | calnexin | -0.0332622 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0329956 |
| ZXDC | ZXD family zinc finger C | -0.0329394 |
| TGFB2 | transforming growth factor, beta 2 | -0.0328452 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0324849 |
| DIAPH3 | diaphanous-related formin 3 | -0.0323037 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0320965 |
| HLA-A | major histocompatibility complex, class I, A | -0.0318526 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0312609 |
| SCFD2 | sec1 family domain containing 2 | -0.0309891 |
| LOX | lysyl oxidase | -0.0308736 |
| HM13 | histocompatibility (minor) 13 | -0.0303773 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0301041 |
| COG6 | component of oligomeric golgi complex 6 | -0.0299965 |
| CALR | calreticulin | -0.0298026 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0297348 |
| FLNB | filamin B, beta | -0.0293439 |
| ARF4 | ADP-ribosylation factor 4 | -0.0293438 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0288491 |
| B2M | beta-2-microglobulin | -0.0285677 |
| RAD21 | RAD21 homolog (S. pombe) | -0.028535 |
| TXNRD1 | thioredoxin reductase 1 | -0.0279641 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0274105 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0273444 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.02695 |
| TLN1 | talin 1 | -0.0268466 |
| NEK7 | NIMA-related kinase 7 | -0.0264678 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0264252 |
| UBC | ubiquitin C | -0.0263147 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0260611 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.025854 |
| TUBB | tubulin, beta class I | -0.0257695 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0257247 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0257038 |
| CUL4B | cullin 4B | -0.0254619 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0254269 |
| MT2A | metallothionein 2A | -0.0253616 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.025177 |
| ARF1 | ADP-ribosylation factor 1 | -0.0249393 |
| COG5 | component of oligomeric golgi complex 5 | -0.024566 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0245603 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0242043 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.024099 |
| SUCO | SUN domain containing ossification factor | -0.0238529 |
| USP15 | ubiquitin specific peptidase 15 | -0.0238307 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0237779 |
| GOLGA3 | golgin A3 | -0.0236902 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0236632 |
| TMEM39A | transmembrane protein 39A | -0.0235504 |
| CTSD | cathepsin D | -0.0235193 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0234773 |
| HLA-C | major histocompatibility complex, class I, C | -0.0230977 |
| DEK | DEK proto-oncogene | -0.0230737 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0228539 |
| ECT2 | epithelial cell transforming 2 | -0.0228476 |
| VCL | vinculin | -0.0228375 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0226797 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0217635 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0217393 |
| TENM3 | teneurin transmembrane protein 3 | -0.0217055 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0216249 |
| COPA | coatomer protein complex, subunit alpha | -0.0216 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0215439 |
| GOLT1B | golgi transport 1B | -0.02148 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0214044 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0213857 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0213354 |
