| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.126301 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0979626 |
| ANXA1 | annexin A1 | 0.0730119 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0590443 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0543212 |
| XPO1 | exportin 1 | 0.0541232 |
| CDK6 | cyclin-dependent kinase 6 | 0.0522107 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0484408 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0464094 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.043873 |
| EMP1 | epithelial membrane protein 1 | 0.0416365 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0416137 |
| EZR | ezrin | 0.0415921 |
| VEGFA | vascular endothelial growth factor A | 0.0400715 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0400017 |
| MACROD2 | MACRO domain containing 2 | 0.0387681 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.037908 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0371598 |
| FAT1 | FAT atypical cadherin 1 | 0.0356714 |
| KRT8 | keratin 8, type II | 0.0354019 |
| DSPP | dentin sialophosphoprotein | 0.034446 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0332545 |
| AGR3 | anterior gradient 3 | 0.0326797 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0325577 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0325562 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0318068 |
| PKM | pyruvate kinase, muscle | 0.0304819 |
| LCN2 | lipocalin 2 | 0.0304661 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0300309 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0299007 |
| HLA-A | major histocompatibility complex, class I, A | 0.0290828 |
| B2M | beta-2-microglobulin | 0.0286134 |
| UBB | ubiquitin B | 0.0283492 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0263591 |
| BRD2 | bromodomain containing 2 | 0.0259558 |
| NEK6 | NIMA-related kinase 6 | 0.0254954 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.0251637 |
| ENO1 | enolase 1, (alpha) | 0.0251237 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0251222 |
| HMGB2 | high mobility group box 2 | 0.0246379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0246157 |
| OGA | O-GlcNAcase | 0.0244682 |
| KRT18 | keratin 18, type I | 0.0242805 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0239875 |
| CTSB | cathepsin B | 0.0239578 |
| SET | SET nuclear proto-oncogene | 0.0236074 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0235803 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0235674 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.023421 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0233892 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.0233344 |
| DENND4C | DENN/MADD domain containing 4C | 0.0233343 |
| MYOF | myoferlin | 0.0232834 |
| ARRDC3 | arrestin domain containing 3 | 0.0232728 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0230938 |
| BCL2L1 | BCL2-like 1 | 0.0228658 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0227269 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0225811 |
| PYGB | phosphorylase, glycogen; brain | 0.0222813 |
| SDC4 | syndecan 4 | 0.0217834 |
| FTL | ferritin, light polypeptide | 0.0216537 |
| ITGB4 | integrin, beta 4 | 0.0212959 |
| SFTPA2 | surfactant protein A2 | 0.0211831 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0207568 |
| RPLP1 | ribosomal protein, large, P1 | 0.0204423 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0202277 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0198567 |
| FLNA | filamin A, alpha | 0.0195772 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0193799 |
| GSN | gelsolin | 0.0192833 |
| USP53 | ubiquitin specific peptidase 53 | 0.0186187 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0185723 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0185329 |
| RPS3 | ribosomal protein S3 | 0.0184954 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0184326 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0183787 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0183692 |
| EFNB2 | ephrin-B2 | 0.0180995 |
| ATF3 | activating transcription factor 3 | 0.0178245 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.0178188 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0177191 |
| AHR | aryl hydrocarbon receptor | 0.0176585 |
| ADD3 | adducin 3 (gamma) | 0.0173016 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0169362 |
| RYBP | RING1 and YY1 binding protein | 0.0168663 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0168518 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 | 0.0167285 |
| CALR | calreticulin | 0.0166518 |
| KIAA1217 | KIAA1217 | 0.0165353 |
| INTS6 | integrator complex subunit 6 | 0.0164358 |
| GATA6 | GATA binding protein 6 | 0.0163708 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0160467 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0160268 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0159971 |
| APP | amyloid beta (A4) precursor protein | 0.0159826 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0159106 |
| CD24 | CD24 molecule | 0.0155695 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.015393 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 0.0150885 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0146718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.196649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181196 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.163143 |
| NPSR1 | neuropeptide S receptor 1 | -0.0935495 |
| CD2AP | CD2-associated protein | -0.0829474 |
| FLNB | filamin B, beta | -0.071654 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0675009 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0650279 |
| ZNF292 | zinc finger protein 292 | -0.0632663 |
| PLSCR1 | phospholipid scramblase 1 | -0.0615954 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0603693 |
| H1-0 | H1.0 linker histone | -0.0591532 |
| RRBP1 | ribosome binding protein 1 | -0.0582086 |
| TJP1 | tight junction protein 1 | -0.0576509 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0562543 |
| ATXN1 | ataxin 1 | -0.0542262 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0533974 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0528838 |
| TMC5 | transmembrane channel-like 5 | -0.0522466 |
| GOLGA4 | golgin A4 | -0.0519504 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0516398 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0499859 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0484669 |
| LMO7 | LIM domain 7 | -0.0480415 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0465579 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0458798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0446397 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0443488 |
| ASPH | aspartate beta-hydroxylase | -0.0436669 |
| MCU | mitochondrial calcium uniporter | -0.0435942 |
| EHBP1 | EH domain binding protein 1 | -0.0432432 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0430198 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0429957 |
| TMEM123 | transmembrane protein 123 | -0.0427875 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0424995 |
| SPAG9 | sperm associated antigen 9 | -0.0422487 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0421278 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0411429 |
| MED13 | mediator complex subunit 13 | -0.0409292 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0408892 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0407831 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0404796 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0404219 |
| ANLN | anillin, actin binding protein | -0.0403483 |
| CLTC | clathrin, heavy chain (Hc) | -0.0396926 |
| NF1 | neurofibromin 1 | -0.0390614 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0388867 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0387955 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0387896 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0387145 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0384221 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0378321 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0376179 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0375254 |
| GSK3B | glycogen synthase kinase 3 beta | -0.037442 |
| DIAPH3 | diaphanous-related formin 3 | -0.0370195 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0359442 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.035938 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0357844 |
| COBL | cordon-bleu WH2 repeat protein | -0.0355322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0354065 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0353183 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0352355 |
| ECT2 | epithelial cell transforming 2 | -0.0348954 |
| XAF1 | XIAP associated factor 1 | -0.0342605 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0340465 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0338641 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0333779 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0332358 |
| USP34 | ubiquitin specific peptidase 34 | -0.0331332 |
| SNX9 | sorting nexin 9 | -0.0330299 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0329915 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0329274 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0327836 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0327254 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324465 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0322981 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0322924 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0322381 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0321749 |
| LAMA4 | laminin, alpha 4 | -0.0321486 |
| SETX | senataxin | -0.0321022 |
| DIAPH2 | diaphanous-related formin 2 | -0.0319445 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318949 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0318264 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0318241 |
| CALU | calumenin | -0.0316464 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0314914 |
| FAM135A | family with sequence similarity 135, member A | -0.031126 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0310951 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0310506 |
| STK24 | serine/threonine kinase 24 | -0.0309154 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.030877 |
| WWC1 | WW and C2 domain containing 1 | -0.0307928 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0307307 |
| HDAC9 | histone deacetylase 9 | -0.0306058 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0306026 |
| CUX1 | cut-like homeobox 1 | -0.030502 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0304399 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0303845 |
