| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.134602 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0427567 |
| XPO1 | exportin 1 | 0.0373564 |
| EGR1 | early growth response 1 | 0.0351367 |
| PTCHD4 | patched domain containing 4 | 0.0287884 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0224927 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0208861 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193418 |
| INTS6 | integrator complex subunit 6 | 0.0186105 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0172406 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0171648 |
| RIGI | RNA sensor RIG-I | 0.0168795 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0161605 |
| MCL1 | myeloid cell leukemia 1 | 0.0158045 |
| NAV1 | neuron navigator 1 | 0.0156367 |
| TENM2 | teneurin transmembrane protein 2 | 0.014868 |
| PTMA | prothymosin, alpha | 0.0136921 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0135435 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0131136 |
| RAD51B | RAD51 paralog B | 0.012787 |
| FOXP1 | forkhead box P1 | 0.0127421 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0125814 |
| ATXN1 | ataxin 1 | 0.012066 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0117646 |
| RNF150 | ring finger protein 150 | 0.0117304 |
| TEX14 | testis expressed 14 | 0.0113654 |
| OPHN1 | oligophrenin 1 | 0.0109654 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0109305 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0108314 |
| NLGN1 | neuroligin 1 | 0.0105298 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0104813 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0102486 |
| PCDH11X | protocadherin 11 X-linked | 0.0101554 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0100563 |
| AEBP2 | AE binding protein 2 | 0.00972078 |
| DISC1 | disrupted in schizophrenia 1 | 0.00964482 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.0095509 |
| VMP1 | vacuole membrane protein 1 | 0.00948991 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00946955 |
| RNF213 | ring finger protein 213 | 0.00916916 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00906641 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.00894121 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.00885943 |
| MKI67 | marker of proliferation Ki-67 | 0.00881806 |
| CEP112 | centrosomal protein 112kDa | 0.00880992 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00872341 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00853759 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0081415 |
| ATG10 | autophagy related 10 | 0.00805426 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0079047 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00789982 |
| SNX29 | sorting nexin 29 | 0.00754581 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00748964 |
| GPR176 | G protein-coupled receptor 176 | 0.00748481 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.00728437 |
| ANO10 | anoctamin 10 | 0.00723016 |
| CPNE1 | copine I | 0.00721392 |
| ARRDC3 | arrestin domain containing 3 | 0.00714222 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.00711957 |
| NABP1 | nucleic acid binding protein 1 | 0.00703224 |
| SECISBP2 | SECIS binding protein 2 | 0.00700157 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00693044 |
| NEK11 | NIMA-related kinase 11 | 0.00689403 |
| LRRC23 | leucine rich repeat containing 23 | 0.00688322 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00687719 |
| DTNB | dystrobrevin, beta | 0.00680087 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00679994 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.00678891 |
| FAT4 | FAT atypical cadherin 4 | 0.00678776 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.00678244 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | 0.00671739 |
| DMXL1 | Dmx-like 1 | 0.00667856 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.00656001 |
| WHRN | whirlin | 0.00648603 |
| TGFB1 | transforming growth factor, beta 1 | 0.00645862 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.00643224 |
| FMNL2 | formin-like 2 | 0.00642668 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.00640332 |
| LMNA | lamin A/C | 0.00638583 |
| STK38 | serine/threonine kinase 38 | 0.00637802 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.00630721 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.00628415 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.00626966 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00622435 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00622259 |
| PXDNL | peroxidasin-like | 0.00621383 |
| CNTLN | centlein, centrosomal protein | 0.00618506 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.00617967 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0061665 |
| TLK2 | tousled-like kinase 2 | 0.00610565 |
| ATF3 | activating transcription factor 3 | 0.00609966 |
| TNNC1 | troponin C type 1 (slow) | 0.00609406 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00605093 |
| UTRN | utrophin | 0.00603733 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0059978 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00599163 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00598979 |
| ZNF532 | zinc finger protein 532 | 0.00598508 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.00596566 |
| STX8 | syntaxin 8 | 0.00593754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181756 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.146751 |
| DTNA | dystrobrevin, alpha | -0.133192 |
| VIM | vimentin | -0.0862244 |
| LSAMP | limbic system-associated membrane protein | -0.0853818 |
| RPS6 | ribosomal protein S6 | -0.0847432 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0788923 |
| FTL | ferritin, light polypeptide | -0.0778189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.075129 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0571721 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0565183 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0531166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0528117 |
| RPS27A | ribosomal protein S27a | -0.0527091 |
| RPS12 | ribosomal protein S12 | -0.0516785 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0492536 |
| UBC | ubiquitin C | -0.0463172 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0459459 |
| GPC6 | glypican 6 | -0.0453488 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0452874 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0436157 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0433729 |
| RPL23 | ribosomal protein L23 | -0.0419832 |
| MYO10 | myosin X | -0.0413174 |
| GOLGA4 | golgin A4 | -0.0396543 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0396244 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0382906 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0377102 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.037045 |
| USP34 | ubiquitin specific peptidase 34 | -0.0364972 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0355296 |
| RUNX1 | runt-related transcription factor 1 | -0.0353231 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0353125 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0343713 |
| MMP12 | matrix metallopeptidase 12 | -0.0343521 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0335793 |
| ACTG1 | actin gamma 1 | -0.0333504 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0327709 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0327602 |
| STC1 | stanniocalcin 1 | -0.0327411 |
| LIMA1 | LIM domain and actin binding 1 | -0.0325967 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0324236 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0318553 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0318475 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0315173 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0313749 |
| SPAG9 | sperm associated antigen 9 | -0.0313077 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0312351 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0311893 |
| RPS3 | ribosomal protein S3 | -0.0309748 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0306539 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0298323 |
| RPL37A | ribosomal protein L37a | -0.0296348 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0295434 |
| JMJD1C | jumonji domain containing 1C | -0.0291923 |
| PKM | pyruvate kinase, muscle | -0.0285896 |
| NUP58 | nucleoporin 58 | -0.0285137 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0281326 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0279983 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0278377 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0273952 |
| EFNA5 | ephrin-A5 | -0.0273638 |
| YBX3 | Y box binding protein 3 | -0.0269591 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0269237 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0267997 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.026725 |
| ANXA2 | annexin A2 | -0.026514 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263196 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0262923 |
| PGK1 | phosphoglycerate kinase 1 | -0.0259909 |
| CANX | calnexin | -0.0259725 |
| RPL12 | ribosomal protein L12 | -0.02597 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.025938 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0258215 |
| RPS19 | ribosomal protein S19 | -0.0250235 |
| WDR45B | WD repeat domain 45B | -0.0249664 |
| RPL8 | ribosomal protein L8 | -0.0244503 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0244351 |
| ATP13A3 | ATPase type 13A3 | -0.024342 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024301 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0241661 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0235203 |
| PTK2 | protein tyrosine kinase 2 | -0.0234145 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.02337 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.023218 |
| RPL36 | ribosomal protein L36 | -0.0231107 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0230961 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0230579 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0230389 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0229561 |
| CDK6 | cyclin-dependent kinase 6 | -0.022844 |
| NBAS | neuroblastoma amplified sequence | -0.0228086 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0227975 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0225246 |
| TXNIP | thioredoxin interacting protein | -0.0225111 |
| ENO1 | enolase 1, (alpha) | -0.0224548 |
| RPS8 | ribosomal protein S8 | -0.0224536 |
| RBM25 | RNA binding motif protein 25 | -0.0224062 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0223862 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0222433 |
