| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0303321 |
| XPO1 | exportin 1 | 0.0218469 |
| CCNG2 | cyclin G2 | 0.0200666 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0177894 |
| OGA | O-GlcNAcase | 0.0164448 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0160455 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0147077 |
| ANO10 | anoctamin 10 | 0.0140099 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.013993 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0130028 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0128611 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0124274 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0114824 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0112019 |
| MACROD2 | MACRO domain containing 2 | 0.0108742 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0108483 |
| DMXL1 | Dmx-like 1 | 0.0107714 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | 0.00966485 |
| RASEF | RAS and EF-hand domain containing | 0.00849497 |
| TUFT1 | tuftelin 1 | 0.0084059 |
| ZDHHC11B | zinc finger, DHHC-type containing 11B | 0.00833999 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00808095 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00747155 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.00747041 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00740382 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00737921 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | 0.00716268 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00714964 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00700105 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00686011 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.00669368 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00668611 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00664455 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.00657577 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00647877 |
| WHRN | whirlin | 0.00644205 |
| DUSP10 | dual specificity phosphatase 10 | 0.00640745 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00638127 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00634958 |
| RIMBP2 | RIMS binding protein 2 | 0.00629972 |
| VEGFA | vascular endothelial growth factor A | 0.00629268 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00626086 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.00624483 |
| FHL2 | four and a half LIM domains 2 | 0.00617752 |
| ARFGEF3 | ARFGEF family member 3 | 0.00611473 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.00605626 |
| DENND4C | DENN/MADD domain containing 4C | 0.00604526 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00596552 |
| NUDT16 | nudix (nucleoside diphosphate linked moiety X)-type motif 16 | 0.0059582 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.0059042 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00589241 |
| SQSTM1 | sequestosome 1 | 0.00588414 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00579068 |
| SLC22A15 | solute carrier family 22, member 15 | 0.00572025 |
| PRELID2 | PRELI domain containing 2 | 0.00557518 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.00557133 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.00556748 |
| PTEN | phosphatase and tensin homolog | 0.00550451 |
| OCLN | occludin | 0.00544235 |
| SMAP1 | small ArfGAP 1 | 0.00541356 |
| RND3 | Rho family GTPase 3 | 0.00541312 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.00537956 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 | 0.00537188 |
| TMC5 | transmembrane channel-like 5 | 0.00534172 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.00531907 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00530933 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00529002 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00523199 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00519322 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00516113 |
| UBE3D | ubiquitin protein ligase E3D | 0.00513642 |
| CAPN5 | calpain 5 | 0.00508728 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00507273 |
| EFNA5 | ephrin-A5 | 0.00507268 |
| RYBP | RING1 and YY1 binding protein | 0.0049995 |
| MEF2A | myocyte enhancer factor 2A | 0.00497318 |
| ARRDC3 | arrestin domain containing 3 | 0.00497266 |
| ANKRD13A | ankyrin repeat domain 13A | 0.00494217 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00490251 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00488914 |
| UST | uronyl-2-sulfotransferase | 0.00482619 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00479872 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.00473468 |
| GSE1 | Gse1 coiled-coil protein | 0.0046918 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00460585 |
| PTCH1 | patched 1 | 0.00457259 |
| TPD52L1 | tumor protein D52-like 1 | 0.00454249 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00452729 |
| STX16 | syntaxin 16 | 0.00450723 |
| ATF3 | activating transcription factor 3 | 0.00448456 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.00446574 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00443122 |
| PARVA | parvin, alpha | 0.0043567 |
| MPC1 | mitochondrial pyruvate carrier 1 | 0.0043119 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0042753 |
| NEBL | nebulette | 0.00421343 |
| MUC13 | mucin 13, cell surface associated | 0.00419292 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.00419197 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.00419137 |
| TMEM65 | transmembrane protein 65 | 0.00418432 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.155388 |
| TMSB10 | thymosin beta 10 | -0.121713 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.115334 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111047 |
| NPSR1 | neuropeptide S receptor 1 | -0.106622 |
| RPS6 | ribosomal protein S6 | -0.0920965 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0816043 |
| ACTG1 | actin gamma 1 | -0.0803571 |
| KRT18 | keratin 18, type I | -0.0797624 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0745952 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0731294 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0718359 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0714885 |
| ANXA2 | annexin A2 | -0.0689835 |
| FAT1 | FAT atypical cadherin 1 | -0.0680757 |
| ITGA6 | integrin, alpha 6 | -0.0649317 |
| S100A6 | S100 calcium binding protein A6 | -0.0648763 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0635264 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0598317 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0593648 |
| KRT8 | keratin 8, type II | -0.0543462 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0513855 |
| H1-0 | H1.0 linker histone | -0.0488874 |
| RPS8 | ribosomal protein S8 | -0.0471991 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0462061 |
| PKM | pyruvate kinase, muscle | -0.0456509 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0437875 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0423896 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0402855 |
| LDHA | lactate dehydrogenase A | -0.0393501 |
| POTEF | POTE ankyrin domain family, member F | -0.0390579 |
| EPCAM | epithelial cell adhesion molecule | -0.0390155 |
| ONECUT3 | one cut homeobox 3 | -0.0389743 |
| RPL23 | ribosomal protein L23 | -0.0386774 |
| PIGR | polymeric immunoglobulin receptor | -0.0384116 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0383152 |
| RPS19 | ribosomal protein S19 | -0.0383095 |
| FLNB | filamin B, beta | -0.0383058 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0378569 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0377741 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0376474 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0372465 |
| TPM4 | tropomyosin 4 | -0.0361637 |
| PGK1 | phosphoglycerate kinase 1 | -0.0360996 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0357236 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0349932 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0348383 |
| S100P | S100 calcium binding protein P | -0.0330033 |
| RPL35A | ribosomal protein L35a | -0.0328082 |
| RPLP1 | ribosomal protein, large, P1 | -0.0327694 |
| CALB1 | calbindin 1, 28kDa | -0.0324921 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0324872 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0324778 |
| KIF5B | kinesin family member 5B | -0.0318152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.031641 |
| RPL11 | ribosomal protein L11 | -0.0316047 |
| RPLP0 | ribosomal protein, large, P0 | -0.0312796 |
| RPL26 | ribosomal protein L26 | -0.0312519 |
| DSPP | dentin sialophosphoprotein | -0.031011 |
| RPL34 | ribosomal protein L34 | -0.0308352 |
| ACTN4 | actinin, alpha 4 | -0.0305837 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0303093 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0301517 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0301472 |
| RPS12 | ribosomal protein S12 | -0.0298253 |
| PERP | PERP, TP53 apoptosis effector | -0.0293957 |
| PRSS3 | protease, serine, 3 | -0.028865 |
| ASPH | aspartate beta-hydroxylase | -0.0288427 |
| RAB10 | RAB10, member RAS oncogene family | -0.0285891 |
| MED13L | mediator complex subunit 13-like | -0.0282981 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0282158 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0279228 |
| B2M | beta-2-microglobulin | -0.0278263 |
| TNS4 | tensin 4 | -0.027493 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0272219 |
| TXNIP | thioredoxin interacting protein | -0.0268673 |
| RPL19 | ribosomal protein L19 | -0.0268153 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0267837 |
| FERMT1 | fermitin family member 1 | -0.0267684 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0264705 |
| FTL | ferritin, light polypeptide | -0.026124 |
| RPS3 | ribosomal protein S3 | -0.0258375 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0253494 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0253143 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0252411 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0249059 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248604 |
| SH3D19 | SH3 domain containing 19 | -0.0248074 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.024582 |
| EHBP1 | EH domain binding protein 1 | -0.0241793 |
| RPS27A | ribosomal protein S27a | -0.0240764 |
| ENO1 | enolase 1, (alpha) | -0.0240746 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0240394 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0239397 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0238658 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0238187 |
| RPL8 | ribosomal protein L8 | -0.0237274 |
| RPS23 | ribosomal protein S23 | -0.0236928 |
| KRT19 | keratin 19, type I | -0.0235605 |
| TPI1 | triosephosphate isomerase 1 | -0.0233194 |
