| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.175116 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.117129 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.107597 |
| FAT1 | FAT atypical cadherin 1 | 0.106017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.072002 |
| XPO1 | exportin 1 | 0.0654658 |
| PLAC8 | placenta-specific 8 | 0.0639808 |
| TXNRD1 | thioredoxin reductase 1 | 0.0577216 |
| TRIM2 | tripartite motif containing 2 | 0.0542926 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0534726 |
| UST | uronyl-2-sulfotransferase | 0.0475928 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0449753 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0449683 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0419581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417091 |
| EZR | ezrin | 0.0393768 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0381117 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0330561 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0330182 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0309638 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0308788 |
| ANXA11 | annexin A11 | 0.0307248 |
| BCL2L1 | BCL2-like 1 | 0.0303004 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.02972 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0295895 |
| CALB1 | calbindin 1, 28kDa | 0.0292282 |
| PTEN | phosphatase and tensin homolog | 0.0274969 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0273069 |
| SHROOM3 | shroom family member 3 | 0.0272937 |
| WWC1 | WW and C2 domain containing 1 | 0.0272495 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0268691 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0267296 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0261576 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0261492 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0260355 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0260157 |
| ARRDC3 | arrestin domain containing 3 | 0.0254511 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0254017 |
| RPL3 | ribosomal protein L3 | 0.0253522 |
| ANXA3 | annexin A3 | 0.0253069 |
| CCNG2 | cyclin G2 | 0.0248054 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0247749 |
| ATF3 | activating transcription factor 3 | 0.0242398 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0241159 |
| SLTM | SAFB-like, transcription modulator | 0.0239608 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0239403 |
| MYO6 | myosin VI | 0.0238995 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0236947 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0236009 |
| EMP1 | epithelial membrane protein 1 | 0.0234655 |
| TRIM56 | tripartite motif containing 56 | 0.0232993 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0224462 |
| FHL2 | four and a half LIM domains 2 | 0.0216784 |
| AFDN | afadin, adherens junction formation factor | 0.0216279 |
| SULT1C4 | sulfotransferase family, cytosolic, 1C, member 4 | 0.0214899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0213828 |
| OGA | O-GlcNAcase | 0.0212495 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.021097 |
| TPM1 | tropomyosin 1 (alpha) | 0.0210069 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0209903 |
| DENND4C | DENN/MADD domain containing 4C | 0.0207188 |
| UPP1 | uridine phosphorylase 1 | 0.0206204 |
| LATS2 | large tumor suppressor kinase 2 | 0.0205065 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0202346 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0200918 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0200842 |
| CDK19 | cyclin-dependent kinase 19 | 0.020071 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0200643 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0200057 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0198327 |
| TRIM31 | tripartite motif containing 31 | 0.0197908 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0197571 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0196349 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0195352 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0194746 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0193112 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0192867 |
| CCNG1 | cyclin G1 | 0.0192828 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0191382 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.018561 |
| OPTN | optineurin | 0.0185307 |
| KIF5B | kinesin family member 5B | 0.0183274 |
| HLA-E | major histocompatibility complex, class I, E | 0.0183007 |
| YME1L1 | YME1-like 1 ATPase | 0.0181556 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0180697 |
| FAM169A | family with sequence similarity 169, member A | 0.0178548 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0177492 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0177373 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.017642 |
| AUTS2 | autism susceptibility candidate 2 | 0.0176044 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0174922 |
| GPHN | gephyrin | 0.0174478 |
| MYO10 | myosin X | 0.0174096 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0173517 |
| XPOT | exportin, tRNA | 0.0172876 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0171627 |
| TSPAN8 | tetraspanin 8 | 0.0170327 |
| MX2 | MX dynamin-like GTPase 2 | 0.0166895 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0165812 |
| DSTN | destrin (actin depolymerizing factor) | 0.0165511 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.197269 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.179129 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.164005 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.130616 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.118365 |
| INTS6 | integrator complex subunit 6 | -0.0983098 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0981939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0981229 |
| RPLP1 | ribosomal protein, large, P1 | -0.0970982 |
| ACTG1 | actin gamma 1 | -0.0899597 |
| ANXA2 | annexin A2 | -0.0887313 |
| RPS6 | ribosomal protein S6 | -0.087693 |
| LMO7 | LIM domain 7 | -0.0794792 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0743104 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0682938 |
| RPS19 | ribosomal protein S19 | -0.0672469 |
| RPS12 | ribosomal protein S12 | -0.0660593 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0631505 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0630014 |
| DENND1A | DENN/MADD domain containing 1A | -0.0628241 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0616954 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0602722 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0602505 |
| PRELID2 | PRELI domain containing 2 | -0.0590904 |
| RPL23 | ribosomal protein L23 | -0.0587354 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0586456 |
| RPL26 | ribosomal protein L26 | -0.0577815 |
| RAD51B | RAD51 paralog B | -0.0576752 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0576462 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.055798 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0545171 |
| MSI2 | musashi RNA-binding protein 2 | -0.0544586 |
| RPS8 | ribosomal protein S8 | -0.054347 |
| RPL37A | ribosomal protein L37a | -0.053667 |
| SP100 | SP100 nuclear antigen | -0.0535744 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0519431 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0515732 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0508279 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0506555 |
| CTBP2 | C-terminal binding protein 2 | -0.050077 |
| FHIT | fragile histidine triad | -0.0484242 |
| HLA-B | major histocompatibility complex, class I, B | -0.0475029 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0472086 |
| LRRC23 | leucine rich repeat containing 23 | -0.0461158 |
| CLIC5 | chloride intracellular channel 5 | -0.0459096 |
| MYO5B | myosin VB | -0.0452183 |
| ASPH | aspartate beta-hydroxylase | -0.0451198 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0449841 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0449398 |
| MCU | mitochondrial calcium uniporter | -0.0430416 |
| NABP1 | nucleic acid binding protein 1 | -0.0428124 |
| RPS24 | ribosomal protein S24 | -0.0420737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0417589 |
| UBAP2 | ubiquitin associated protein 2 | -0.0413347 |
| RPL11 | ribosomal protein L11 | -0.041062 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0408569 |
| RPS21 | ribosomal protein S21 | -0.0407362 |
| RCC1 | regulator of chromosome condensation 1 | -0.0394146 |
| RPL9 | ribosomal protein L9 | -0.0393642 |
| RPS27A | ribosomal protein S27a | -0.039309 |
| FRMD5 | FERM domain containing 5 | -0.0388986 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0374926 |
| RREB1 | ras responsive element binding protein 1 | -0.0374592 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0373974 |
| WWOX | WW domain containing oxidoreductase | -0.036022 |
| RPL35A | ribosomal protein L35a | -0.0358021 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0355398 |
| EGFR | epidermal growth factor receptor | -0.0352991 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0351388 |
| FUS | FUS RNA binding protein | -0.0350884 |
| RCOR1 | REST corepressor 1 | -0.0344347 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0343475 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0342235 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.034193 |
| CUX1 | cut-like homeobox 1 | -0.0336241 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0335472 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334968 |
| SNX14 | sorting nexin 14 | -0.0333239 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0330365 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0329567 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0327954 |
| RPL34 | ribosomal protein L34 | -0.0327338 |
| FBXO11 | F-box protein 11 | -0.0324956 |
| MTAP | methylthioadenosine phosphorylase | -0.0320672 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0316487 |
| SVIL | supervillin | -0.0312823 |
| TMSB10 | thymosin beta 10 | -0.0308272 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0307831 |
| FOXO3 | forkhead box O3 | -0.0307463 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0302074 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0300961 |
| SUMF1 | sulfatase modifying factor 1 | -0.0299837 |
| SMYD3 | SET and MYND domain containing 3 | -0.0299797 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0298757 |
| ADIPOR2 | adiponectin receptor 2 | -0.029837 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0298254 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0297811 |
| NPSR1 | neuropeptide S receptor 1 | -0.0296239 |
| RPLP0 | ribosomal protein, large, P0 | -0.0295749 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0294514 |
