| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.088256 |
| MT2A | metallothionein 2A | 0.0831444 |
| HLA-B | major histocompatibility complex, class I, B | 0.078906 |
| XPO1 | exportin 1 | 0.0737375 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.072432 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0701928 |
| VIM | vimentin | 0.0683483 |
| TP63 | tumor protein p63 | 0.0650017 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0614448 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0585668 |
| DST | dystonin | 0.0566297 |
| B2M | beta-2-microglobulin | 0.0545848 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.05246 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0492731 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0429362 |
| RNF213 | ring finger protein 213 | 0.0411061 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0410213 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0395763 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0377873 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0347061 |
| ENO1 | enolase 1, (alpha) | 0.0340576 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0336887 |
| VMP1 | vacuole membrane protein 1 | 0.0335082 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0323816 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0317217 |
| TPM4 | tropomyosin 4 | 0.0297814 |
| HLA-A | major histocompatibility complex, class I, A | 0.0292959 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0281694 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0275376 |
| SP100 | SP100 nuclear antigen | 0.0271535 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0262407 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0260652 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0256992 |
| CAPRIN2 | caprin family member 2 | 0.0249619 |
| DENND4C | DENN/MADD domain containing 4C | 0.0249617 |
| DMXL1 | Dmx-like 1 | 0.0246191 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0242307 |
| RIGI | RNA sensor RIG-I | 0.0239648 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0239109 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0237941 |
| MT1E | metallothionein 1E | 0.0237687 |
| TRIM56 | tripartite motif containing 56 | 0.0232127 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0227245 |
| PLIN2 | perilipin 2 | 0.022605 |
| PDE10A | phosphodiesterase 10A | 0.0221931 |
| HLA-E | major histocompatibility complex, class I, E | 0.0221522 |
| DNER | delta/notch-like EGF repeat containing | 0.0221154 |
| NDRG1 | N-myc downstream regulated 1 | 0.0216635 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0216284 |
| SDC4 | syndecan 4 | 0.0212107 |
| PMP22 | peripheral myelin protein 22 | 0.0203289 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0203271 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0201842 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0201563 |
| PRELID2 | PRELI domain containing 2 | 0.019799 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0197337 |
| PTK2 | protein tyrosine kinase 2 | 0.0196067 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0195862 |
| PRKCE | protein kinase C, epsilon | 0.0195644 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0192599 |
| MEF2A | myocyte enhancer factor 2A | 0.0192379 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.0191103 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0188489 |
| TXNIP | thioredoxin interacting protein | 0.0187187 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.018641 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0185571 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0184406 |
| PLSCR1 | phospholipid scramblase 1 | 0.018379 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0180394 |
| TPI1 | triosephosphate isomerase 1 | 0.01794 |
| NGFR | nerve growth factor receptor | 0.0175642 |
| MYADM | myeloid-associated differentiation marker | 0.017165 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0170933 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0169979 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0165968 |
| OPTN | optineurin | 0.0163376 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0160838 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0160261 |
| ANGPTL4 | angiopoietin-like 4 | 0.0160027 |
| PRTG | protogenin | 0.016002 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0158784 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | 0.0158615 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0156198 |
| CADM2 | cell adhesion molecule 2 | 0.0155 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0154122 |
| RPL36 | ribosomal protein L36 | 0.0152835 |
| DEK | DEK proto-oncogene | 0.0151458 |
| EFNA5 | ephrin-A5 | 0.0146866 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0144681 |
| STMN1 | stathmin 1 | 0.0142634 |
| CCNL1 | cyclin L1 | 0.0142396 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0140534 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0138912 |
| FHIT | fragile histidine triad | 0.0138616 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0137176 |
| RPL12 | ribosomal protein L12 | 0.0136632 |
| FAM162A | family with sequence similarity 162, member A | 0.0136414 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0134604 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0133851 |
| TUBA1B | tubulin, alpha 1b | 0.0133536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21159 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0973046 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0893567 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0807549 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0665197 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0587568 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0583836 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0583739 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0557664 |
| TOP1 | topoisomerase (DNA) I | -0.054383 |
| TXNRD1 | thioredoxin reductase 1 | -0.0542403 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0484244 |
| EHBP1 | EH domain binding protein 1 | -0.0483919 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0458339 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0457459 |
| AHNAK | AHNAK nucleoprotein | -0.0444421 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0439422 |
| USP34 | ubiquitin specific peptidase 34 | -0.0434752 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0427918 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0426939 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0424726 |
| CANX | calnexin | -0.0424127 |
| CMIP | c-Maf inducing protein | -0.0423899 |
| RAI1 | retinoic acid induced 1 | -0.0393733 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0387731 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0373182 |
| RPL26 | ribosomal protein L26 | -0.0361399 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0354814 |
| ACTG1 | actin gamma 1 | -0.034887 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0348463 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0345721 |
| TMEM41B | transmembrane protein 41B | -0.0340858 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0338631 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0328373 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324986 |
| SMAD3 | SMAD family member 3 | -0.0321604 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0318969 |
| HDLBP | high density lipoprotein binding protein | -0.0316318 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0312683 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0307682 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0305798 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0303811 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0300685 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0299018 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0290832 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0286519 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0280029 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0278721 |
| RACK1 | receptor for activated C kinase 1 | -0.027226 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0267582 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0263992 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0259933 |
| RPS6 | ribosomal protein S6 | -0.0259548 |
| BMERB1 | bMERB domain containing 1 | -0.0258911 |
| MT1X | metallothionein 1X | -0.025696 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0255683 |
| COG5 | component of oligomeric golgi complex 5 | -0.0255611 |
| PLK2 | polo-like kinase 2 | -0.0253272 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0251138 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0249939 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.024887 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0247783 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0247737 |
| TAOK1 | TAO kinase 1 | -0.0247057 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0245743 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0242721 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0241547 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0239148 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0229857 |
| OSMR | oncostatin M receptor | -0.0229539 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0229276 |
| FBXO11 | F-box protein 11 | -0.0227674 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.022635 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.0226267 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0225669 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0223988 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0223908 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0222425 |
| CEP170 | centrosomal protein 170kDa | -0.0220251 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0220102 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0218781 |
| RPS8 | ribosomal protein S8 | -0.021746 |
| WDR26 | WD repeat domain 26 | -0.0217022 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0216688 |
| PYGB | phosphorylase, glycogen; brain | -0.0215989 |
| ARF1 | ADP-ribosylation factor 1 | -0.0215823 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0215028 |
| EGR1 | early growth response 1 | -0.021454 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0211706 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0211615 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0210369 |
| HPCAL1 | hippocalcin-like 1 | -0.0209829 |
| SETX | senataxin | -0.0209524 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0209 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208503 |
| RPL23 | ribosomal protein L23 | -0.0208102 |
| RTN4 | reticulon 4 | -0.0205842 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0205135 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0204458 |
| RASA2 | RAS p21 protein activator 2 | -0.0204182 |
