| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.0656024 |
| XPO1 | exportin 1 | 0.0473696 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0294127 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0264012 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0221367 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.015657 |
| RNF150 | ring finger protein 150 | 0.0143386 |
| STK32A | serine/threonine kinase 32A | 0.0138489 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0130755 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0128258 |
| ANK2 | ankyrin 2, neuronal | 0.0127452 |
| UST | uronyl-2-sulfotransferase | 0.0119202 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.0113961 |
| AOPEP | aminopeptidase O (putative) | 0.0113934 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0111952 |
| GPR39 | G protein-coupled receptor 39 | 0.010713 |
| ATF7 | activating transcription factor 7 | 0.0106078 |
| THBS1 | thrombospondin 1 | 0.0105768 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.01034 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0102826 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0100768 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.00984787 |
| RHCG | Rh family, C glycoprotein | 0.00983706 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00966447 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.00957793 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.00952136 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00928017 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0090571 |
| SNX9 | sorting nexin 9 | 0.00883566 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00880507 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.00877062 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00876672 |
| OXSR1 | oxidative stress responsive 1 | 0.00831486 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.00831122 |
| HDAC9 | histone deacetylase 9 | 0.00829969 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00828111 |
| UBE3D | ubiquitin protein ligase E3D | 0.00827969 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00819406 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00815721 |
| CDK14 | cyclin-dependent kinase 14 | 0.00803024 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.00794666 |
| GALK2 | galactokinase 2 | 0.00793684 |
| FOXP2 | forkhead box P2 | 0.00790475 |
| CDK12 | cyclin-dependent kinase 12 | 0.00789556 |
| NUBPL | nucleotide binding protein-like | 0.00777787 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.00773703 |
| RNF217 | ring finger protein 217 | 0.00767196 |
| CCNG2 | cyclin G2 | 0.00757165 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.0075663 |
| REEP3 | receptor accessory protein 3 | 0.00749797 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0074658 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00741341 |
| GPR176 | G protein-coupled receptor 176 | 0.00727051 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.00723067 |
| DHFR | dihydrofolate reductase | 0.00720139 |
| WASHC4 | WASH complex subunit 4 | 0.00719243 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.00716997 |
| MIPOL1 | mirror-image polydactyly 1 | 0.00711645 |
| KIAA0586 | KIAA0586 | 0.00704075 |
| RSU1 | Ras suppressor protein 1 | 0.00703837 |
| CEP83 | centrosomal protein 83kDa | 0.00703697 |
| DMXL1 | Dmx-like 1 | 0.00702858 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0070236 |
| RNF169 | ring finger protein 169 | 0.00693607 |
| STARD9 | StAR-related lipid transfer (START) domain containing 9 | 0.00687997 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00685601 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00677814 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.00670447 |
| FRMD3 | FERM domain containing 3 | 0.00670189 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.00668129 |
| SYT1 | synaptotagmin I | 0.00667968 |
| ITGB8 | integrin, beta 8 | 0.00666624 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 0.00664919 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.00663305 |
| ZNF146 | zinc finger protein 146 | 0.00660681 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00657425 |
| RBPMS | RNA binding protein with multiple splicing | 0.00649779 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00647501 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.00638116 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.00635513 |
| TNS1 | tensin 1 | 0.00628852 |
| PTEN | phosphatase and tensin homolog | 0.00616364 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00612902 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.00605515 |
| KIF13A | kinesin family member 13A | 0.00594851 |
| ALPK1 | alpha-kinase 1 | 0.0059442 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00588612 |
| PRPF18 | pre-mRNA processing factor 18 | 0.00585165 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.005821 |
| ANXA1 | annexin A1 | 0.00578954 |
| ANTXR1 | anthrax toxin receptor 1 | 0.00569427 |
| NGFR | nerve growth factor receptor | 0.0056704 |
| TGOLN2 | trans-golgi network protein 2 | 0.00567039 |
| RBM47 | RNA binding motif protein 47 | 0.00565909 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00565806 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.00565576 |
| POU6F2 | POU class 6 homeobox 2 | 0.00560961 |
| DGLUCY | D-glutamate cyclase | 0.0055925 |
| FNIP1 | folliculin interacting protein 1 | 0.00558733 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.00557762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16733 |
| TMSB10 | thymosin beta 10 | -0.143967 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.120425 |
| FTL | ferritin, light polypeptide | -0.0945066 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0936644 |
| VIM | vimentin | -0.0900868 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0885684 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0794254 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0739156 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0727993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.067722 |
| CD44 | CD44 molecule (Indian blood group) | -0.0658958 |
| GPC6 | glypican 6 | -0.0645275 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0616377 |
| USP34 | ubiquitin specific peptidase 34 | -0.0608353 |
| GOLGA4 | golgin A4 | -0.0586221 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0585973 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0585471 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0576226 |
| RPLP1 | ribosomal protein, large, P1 | -0.0569 |
| PTMA | prothymosin, alpha | -0.0568922 |
| RPS6 | ribosomal protein S6 | -0.0554359 |
| EFNA5 | ephrin-A5 | -0.0552163 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0546926 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0533816 |
| GLCCI1 | glucocorticoid induced 1 | -0.0523106 |
| RPS19 | ribosomal protein S19 | -0.05159 |
| NRP1 | neuropilin 1 | -0.0511289 |
| RPS12 | ribosomal protein S12 | -0.0505765 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0499399 |
| OSMR | oncostatin M receptor | -0.0490296 |
| MT2A | metallothionein 2A | -0.0487701 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0486422 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0484145 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0483895 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0481159 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0474106 |
| STC1 | stanniocalcin 1 | -0.047311 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0469026 |
| PCBP2 | poly(rC) binding protein 2 | -0.0458415 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0453525 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0438537 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0437875 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436196 |
| NRG1 | neuregulin 1 | -0.0435899 |
| RPS8 | ribosomal protein S8 | -0.0432841 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0426477 |
| RPL37A | ribosomal protein L37a | -0.0421535 |
| FN1 | fibronectin 1 | -0.0421222 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0417528 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0416224 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0412338 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406708 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.040222 |
| RPL23 | ribosomal protein L23 | -0.03988 |
| B2M | beta-2-microglobulin | -0.0392369 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0383829 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0380789 |
| RPS21 | ribosomal protein S21 | -0.0378328 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0375909 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0366325 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0361059 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0360879 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0358966 |
| TOP1 | topoisomerase (DNA) I | -0.0357862 |
| IER3 | immediate early response 3 | -0.035566 |
| RPLP2 | ribosomal protein, large, P2 | -0.0347897 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0347501 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0344729 |
| RPL35A | ribosomal protein L35a | -0.0344331 |
| RPL11 | ribosomal protein L11 | -0.0343894 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0338022 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0332545 |
| RPL32 | ribosomal protein L32 | -0.0332521 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0332188 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0320953 |
| RPL37 | ribosomal protein L37 | -0.032095 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0318922 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0318705 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0317555 |
| ASPH | aspartate beta-hydroxylase | -0.0316183 |
| SIK3 | SIK family kinase 3 | -0.0316174 |
| FAM20C | family with sequence similarity 20, member C | -0.0315102 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314649 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0312979 |
| GNAS | GNAS complex locus | -0.0311169 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307585 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0307174 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0304896 |
| HMGA1 | high mobility group AT-hook 1 | -0.0304567 |
| PRELID2 | PRELI domain containing 2 | -0.0304394 |
| SPAG9 | sperm associated antigen 9 | -0.0304041 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.030146 |
| RPS24 | ribosomal protein S24 | -0.030141 |
| VCL | vinculin | -0.0300294 |
| RPL31 | ribosomal protein L31 | -0.0299322 |
| RPL36 | ribosomal protein L36 | -0.0298192 |
| RPLP0 | ribosomal protein, large, P0 | -0.02979 |
| CDH13 | cadherin 13 | -0.0296588 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0296056 |
