| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.102717 |
| VIM | vimentin | 0.088043 |
| MT2A | metallothionein 2A | 0.0842456 |
| TMSB10 | thymosin beta 10 | 0.0792312 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0696608 |
| RPLP1 | ribosomal protein, large, P1 | 0.0589427 |
| FTL | ferritin, light polypeptide | 0.0589191 |
| XPO1 | exportin 1 | 0.0480723 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0469191 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0461482 |
| CMIP | c-Maf inducing protein | 0.0455508 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0430677 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0415954 |
| RPS29 | ribosomal protein S29 | 0.0410021 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0403642 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0394168 |
| OGA | O-GlcNAcase | 0.0388653 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0386109 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0363406 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0359187 |
| CAVIN1 | caveolae associated protein 1 | 0.0348293 |
| RPL35A | ribosomal protein L35a | 0.0342683 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0337858 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0328084 |
| RPL36 | ribosomal protein L36 | 0.0324663 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.031246 |
| AHNAK | AHNAK nucleoprotein | 0.0311537 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0309458 |
| FUS | FUS RNA binding protein | 0.0308362 |
| RPS19 | ribosomal protein S19 | 0.029755 |
| RPL31 | ribosomal protein L31 | 0.0296764 |
| KYNU | kynureninase | 0.0295183 |
| FMNL2 | formin-like 2 | 0.0287512 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.028221 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0276257 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0255104 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.025489 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0249376 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0245949 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0241399 |
| INTS6 | integrator complex subunit 6 | 0.0238148 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0237415 |
| LMNA | lamin A/C | 0.0233995 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0233303 |
| HLA-E | major histocompatibility complex, class I, E | 0.0229754 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0228849 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0228126 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0225695 |
| HMGB1 | high mobility group box 1 | 0.0225329 |
| KIF13A | kinesin family member 13A | 0.0224396 |
| RBM39 | RNA binding motif protein 39 | 0.0223347 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.021625 |
| S100A10 | S100 calcium binding protein A10 | 0.0216032 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0215806 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0210888 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0210811 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0210296 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0208775 |
| RPL13A | ribosomal protein L13a | 0.0206998 |
| FAM107B | family with sequence similarity 107, member B | 0.0197687 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0197291 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0196474 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0194614 |
| RPS20 | ribosomal protein S20 | 0.0194282 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0194122 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0192431 |
| RPL23 | ribosomal protein L23 | 0.0191729 |
| JMJD1C | jumonji domain containing 1C | 0.0190724 |
| RAD51B | RAD51 paralog B | 0.0187283 |
| NPR2 | natriuretic peptide receptor 2 | 0.0187005 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0186389 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0185913 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0185072 |
| LGMN | legumain | 0.0183403 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0181741 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.018024 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.017933 |
| MED13 | mediator complex subunit 13 | 0.0176986 |
| RPL28 | ribosomal protein L28 | 0.0175393 |
| PDE10A | phosphodiesterase 10A | 0.0174291 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.017138 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0171277 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0171026 |
| CCNG2 | cyclin G2 | 0.0169224 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0169125 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0165227 |
| ZNF638 | zinc finger protein 638 | 0.0163573 |
| RPS27 | ribosomal protein S27 | 0.0161388 |
| VSIG2 | V-set and immunoglobulin domain containing 2 | 0.0161215 |
| ZFHX3 | zinc finger homeobox 3 | 0.0160462 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0159947 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0159567 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0159197 |
| BRD2 | bromodomain containing 2 | 0.0159157 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0157935 |
| ATXN1 | ataxin 1 | 0.015726 |
| SPPL3 | signal peptide peptidase like 3 | 0.0156863 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.01567 |
| KIAA0319 | KIAA0319 | 0.0155217 |
| PYGL | phosphorylase, glycogen, liver | 0.0154887 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.126755 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.118998 |
| TPM3 | tropomyosin 3 | -0.0985492 |
| TXNRD1 | thioredoxin reductase 1 | -0.0983762 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.095943 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0867482 |
| FGB | fibrinogen beta chain | -0.0774853 |
| RPS2 | ribosomal protein S2 | -0.0761995 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0754112 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0735628 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.069109 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0668374 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0657149 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0652329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0633134 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.063093 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0629305 |
| RTN4 | reticulon 4 | -0.061442 |
| WDR43 | WD repeat domain 43 | -0.0601223 |
| GRAMD1B | GRAM domain containing 1B | -0.0594892 |
| KIF5B | kinesin family member 5B | -0.0581138 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0577945 |
| RPS12 | ribosomal protein S12 | -0.0574987 |
| DENND4A | DENN/MADD domain containing 4A | -0.0566749 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.055236 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0543304 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0534348 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0533029 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0527815 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0519466 |
| POTEF | POTE ankyrin domain family, member F | -0.0503675 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.048247 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.04613 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0457775 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0452591 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0429009 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0427227 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0420666 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0406163 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0404803 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0389962 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0388807 |
| LAMB1 | laminin, beta 1 | -0.0378117 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0378008 |
| PM20D1 | peptidase M20 domain containing 1 | -0.037647 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0376179 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0370414 |
| MIS18BP1 | MIS18 binding protein 1 | -0.036288 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0360853 |
| HDGF | hepatoma-derived growth factor | -0.0355863 |
| USP3 | ubiquitin specific peptidase 3 | -0.0352218 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0343038 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.033781 |
| YBX3 | Y box binding protein 3 | -0.033043 |
| RPS6 | ribosomal protein S6 | -0.0328049 |
| PFDN2 | prefoldin subunit 2 | -0.032769 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0323139 |
| ECT2 | epithelial cell transforming 2 | -0.0321117 |
| SRGN | serglycin | -0.0319578 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0318806 |
| MPZL1 | myelin protein zero-like 1 | -0.0317875 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0317865 |
| YBX1 | Y box binding protein 1 | -0.0317732 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.0316129 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0314314 |
| GOLT1B | golgi transport 1B | -0.0313089 |
| CLTC | clathrin, heavy chain (Hc) | -0.0312321 |
| ZNF292 | zinc finger protein 292 | -0.0309908 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0308234 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0306617 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0305489 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304156 |
| SPAG9 | sperm associated antigen 9 | -0.0302873 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0290692 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0287911 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0287039 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0286727 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0283914 |
| IPO7 | importin 7 | -0.0283664 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0281625 |
| CCNL1 | cyclin L1 | -0.0279762 |
| MATR3 | matrin 3 | -0.0279393 |
| STC1 | stanniocalcin 1 | -0.0278821 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0276338 |
| SETD5 | SET domain containing 5 | -0.0273649 |
| IMMT | inner membrane protein, mitochondrial | -0.0271945 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0270246 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0270231 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0269577 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0269271 |
| PNN | pinin, desmosome associated protein | -0.0268294 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0265487 |
| PARD3 | par-3 family cell polarity regulator | -0.0265347 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0265285 |
| MSN | moesin | -0.0264657 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0264511 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0263111 |
| CANX | calnexin | -0.0262309 |
| TPX2 | TPX2, microtubule-associated | -0.0262217 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0260622 |
