| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.107658 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0888373 |
| HDAC9 | histone deacetylase 9 | 0.0806549 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0689775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0619124 |
| IGF2 | insulin-like growth factor 2 | 0.0612017 |
| ANXA1 | annexin A1 | 0.0562683 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0533392 |
| OGA | O-GlcNAcase | 0.0505611 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0471293 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0450673 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0447843 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0440669 |
| AHNAK | AHNAK nucleoprotein | 0.0414399 |
| ACTG1 | actin gamma 1 | 0.0407041 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0405497 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0404962 |
| COL5A2 | collagen, type V, alpha 2 | 0.0398801 |
| NPSR1 | neuropeptide S receptor 1 | 0.0389078 |
| FN1 | fibronectin 1 | 0.0381198 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0378157 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0367514 |
| MT2A | metallothionein 2A | 0.0361305 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0359586 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0356091 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0349401 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0348661 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0341571 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0335698 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0334394 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0333631 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0331021 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.0327627 |
| GPHN | gephyrin | 0.0326397 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0319224 |
| TRIM33 | tripartite motif containing 33 | 0.0319219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0315656 |
| EXOC4 | exocyst complex component 4 | 0.0315072 |
| CNKSR3 | CNKSR family member 3 | 0.0311084 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0305413 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0301026 |
| RPL5 | ribosomal protein L5 | 0.0296341 |
| CD109 | CD109 molecule | 0.028928 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0287884 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0286018 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285277 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0284638 |
| RNF24 | ring finger protein 24 | 0.0283953 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0282233 |
| WLS | wntless Wnt ligand secretion mediator | 0.0278966 |
| CADM2 | cell adhesion molecule 2 | 0.0278179 |
| FBL | fibrillarin | 0.0276524 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0274814 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0273848 |
| CHMP2B | charged multivesicular body protein 2B | 0.0273793 |
| USO1 | USO1 vesicle transport factor | 0.0271581 |
| LYST | lysosomal trafficking regulator | 0.0271558 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0271155 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0270694 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0269991 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0269238 |
| ATXN10 | ataxin 10 | 0.0269012 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.0265997 |
| WDR20 | WD repeat domain 20 | 0.0265826 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0263664 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0263115 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0262158 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0261926 |
| RPS15 | ribosomal protein S15 | 0.0260783 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0260466 |
| SERINC5 | serine incorporator 5 | 0.0257292 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0255774 |
| SFTPA2 | surfactant protein A2 | 0.0255035 |
| KLF6 | Kruppel-like factor 6 | 0.0253692 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0252024 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0251004 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0249141 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248867 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0247728 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.024665 |
| ACTN4 | actinin, alpha 4 | 0.0246441 |
| SMAD3 | SMAD family member 3 | 0.0245862 |
| TCF12 | transcription factor 12 | 0.0245032 |
| NBEA | neurobeachin | 0.0244887 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0244767 |
| UBE3C | ubiquitin protein ligase E3C | 0.0243681 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0242972 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.024296 |
| RYBP | RING1 and YY1 binding protein | 0.0241387 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.023998 |
| CCNI | cyclin I | 0.023985 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0239552 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0236678 |
| G0S2 | G0/G1 switch 2 | 0.0235816 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0234737 |
| NOL10 | nucleolar protein 10 | 0.023469 |
| CDC42SE2 | CDC42 small effector 2 | 0.0234498 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0232867 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0231736 |
| VMP1 | vacuole membrane protein 1 | 0.0229806 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.263529 |
| LAMB3 | laminin, beta 3 | -0.112902 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.103155 |
| TXNRD1 | thioredoxin reductase 1 | -0.100913 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.100243 |
| ASPH | aspartate beta-hydroxylase | -0.0951485 |
| ATOSA | atos homolog A | -0.0853703 |
| RIGI | RNA sensor RIG-I | -0.0842038 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0772103 |
| DTNA | dystrobrevin, alpha | -0.0740708 |
| EGR1 | early growth response 1 | -0.0737726 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0716078 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0711001 |
| LSAMP | limbic system-associated membrane protein | -0.0698831 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0688176 |
| FTL | ferritin, light polypeptide | -0.0635796 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0600736 |
| SMYD3 | SET and MYND domain containing 3 | -0.0593046 |
| KRT17 | keratin 17, type I | -0.0573288 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0560604 |
| USP34 | ubiquitin specific peptidase 34 | -0.0560476 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0558405 |
| PARD3 | par-3 family cell polarity regulator | -0.0545105 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0539068 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0536701 |
| KYNU | kynureninase | -0.0533488 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.05147 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0514394 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0505968 |
| RAI14 | retinoic acid induced 14 | -0.0489436 |
| ANXA2 | annexin A2 | -0.0485281 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0474586 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0474239 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0472586 |
| NEMF | nuclear export mediator factor | -0.0459947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0458283 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0454457 |
| TJP1 | tight junction protein 1 | -0.045052 |
| TLK1 | tousled-like kinase 1 | -0.0446611 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0445371 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0437921 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0437143 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0436801 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0432251 |
| HMGA2 | high mobility group AT-hook 2 | -0.0426384 |
| PTK2 | protein tyrosine kinase 2 | -0.0423149 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0421345 |
| TMEM165 | transmembrane protein 165 | -0.0399059 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0397354 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0396521 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0396039 |
| MXD1 | MAX dimerization protein 1 | -0.0395704 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0394531 |
| KIF13B | kinesin family member 13B | -0.0392931 |
| RIOK3 | RIO kinase 3 | -0.0391501 |
| INHBA | inhibin, beta A | -0.0381477 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0380229 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0379489 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0376363 |
| SPAG9 | sperm associated antigen 9 | -0.0374889 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0365559 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0364901 |
| GLCCI1 | glucocorticoid induced 1 | -0.036429 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.036366 |
| ZNF638 | zinc finger protein 638 | -0.0362317 |
| RNF149 | ring finger protein 149 | -0.0360061 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0359814 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0357708 |
| TMSB10 | thymosin beta 10 | -0.0355443 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0351376 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0348704 |
| MCL1 | myeloid cell leukemia 1 | -0.0344919 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0343956 |
| RBM47 | RNA binding motif protein 47 | -0.0343902 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0341793 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0335343 |
| EFNA5 | ephrin-A5 | -0.0333161 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0329881 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0328771 |
| JUN | jun proto-oncogene | -0.0328066 |
| RCOR1 | REST corepressor 1 | -0.0327569 |
| S100A11 | S100 calcium binding protein A11 | -0.0326956 |
| JUP | junction plakoglobin | -0.0326787 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.032576 |
| MYO1E | myosin IE | -0.0325507 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0323108 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0323037 |
| REPS1 | RALBP1 associated Eps domain containing 1 | -0.03189 |
| STC1 | stanniocalcin 1 | -0.0313844 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.03137 |
| OSMR | oncostatin M receptor | -0.0308669 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0307126 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0305158 |
| WAC | WW domain containing adaptor with coiled-coil | -0.030282 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0301529 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0301315 |
| RAB10 | RAB10, member RAS oncogene family | -0.0299016 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.029658 |
| KIF16B | kinesin family member 16B | -0.0295547 |
| MED13 | mediator complex subunit 13 | -0.0293106 |
