| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.0800845 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0560885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0493121 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0479978 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.047308 |
| CALD1 | caldesmon 1 | 0.0465347 |
| AEBP2 | AE binding protein 2 | 0.0394567 |
| INTS6 | integrator complex subunit 6 | 0.0367153 |
| PDE10A | phosphodiesterase 10A | 0.0347222 |
| VMP1 | vacuole membrane protein 1 | 0.0342355 |
| ANK2 | ankyrin 2, neuronal | 0.0338863 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0338343 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0338285 |
| MCL1 | myeloid cell leukemia 1 | 0.0315468 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0303469 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0296082 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0295788 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0287262 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0276321 |
| MACROD2 | MACRO domain containing 2 | 0.0273986 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0269112 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0264536 |
| ATXN1 | ataxin 1 | 0.0264223 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0259602 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0258354 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0255422 |
| PRKCE | protein kinase C, epsilon | 0.0253118 |
| WWOX | WW domain containing oxidoreductase | 0.0251827 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0242216 |
| FMNL2 | formin-like 2 | 0.0234518 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0234065 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0232634 |
| EXOC4 | exocyst complex component 4 | 0.0223689 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0219181 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0217032 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0213422 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.021155 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0210096 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0207841 |
| BRD2 | bromodomain containing 2 | 0.0206902 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.020245 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0198341 |
| ATF6 | activating transcription factor 6 | 0.0196664 |
| JMJD1C | jumonji domain containing 1C | 0.0196371 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0192321 |
| DSCAM | Down syndrome cell adhesion molecule | 0.018823 |
| YAP1 | Yes-associated protein 1 | 0.0187564 |
| NLGN1 | neuroligin 1 | 0.0187001 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0186549 |
| ANO6 | anoctamin 6 | 0.01855 |
| PRELID2 | PRELI domain containing 2 | 0.0185067 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0183737 |
| WDR70 | WD repeat domain 70 | 0.018209 |
| NABP1 | nucleic acid binding protein 1 | 0.0181813 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.018044 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0179343 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0178452 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0173341 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0173302 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0172338 |
| KAZN | kazrin, periplakin interacting protein | 0.0168631 |
| MAP7 | microtubule-associated protein 7 | 0.0168607 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0168544 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.0165327 |
| DST | dystonin | 0.0165308 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.016138 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0161103 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0160851 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0159004 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0158448 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0157231 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0156492 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0153885 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0153059 |
| TPM2 | tropomyosin 2 (beta) | 0.0152802 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0152535 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0152259 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | 0.0152151 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0151933 |
| UBAP2 | ubiquitin associated protein 2 | 0.0150217 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0149247 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.014745 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0146161 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0145356 |
| FHIT | fragile histidine triad | 0.0145048 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0143341 |
| MRTFA | myocardin related transcription factor A | 0.0141453 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0141198 |
| MMP12 | matrix metallopeptidase 12 | 0.014049 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0139969 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0138329 |
| TRIM59 | tripartite motif containing 59 | 0.013743 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0137209 |
| NOTCH2 | notch 2 | 0.0136612 |
| SMYD3 | SET and MYND domain containing 3 | 0.0135936 |
| CUL4A | cullin 4A | 0.0135854 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.013546 |
| GPHN | gephyrin | 0.0134777 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0134539 |
| RBM19 | RNA binding motif protein 19 | 0.0134327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.269527 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.124504 |
| TXNRD1 | thioredoxin reductase 1 | -0.116958 |
| VIM | vimentin | -0.106331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0946399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0940995 |
| PTMA | prothymosin, alpha | -0.0857881 |
| TMSB10 | thymosin beta 10 | -0.0766537 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0595368 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0592252 |
| TPI1 | triosephosphate isomerase 1 | -0.0584578 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0562043 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0557191 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0516465 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0488284 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0481119 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0466616 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.045632 |
| MKI67 | marker of proliferation Ki-67 | -0.0456205 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0449302 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.044719 |
| RPS8 | ribosomal protein S8 | -0.0441079 |
| PHIP | pleckstrin homology domain interacting protein | -0.044027 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0438181 |
| RPL12 | ribosomal protein L12 | -0.0436113 |
| RPL35A | ribosomal protein L35a | -0.0433074 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0429716 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0429185 |
| RPS21 | ribosomal protein S21 | -0.0421509 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0411781 |
| PGK1 | phosphoglycerate kinase 1 | -0.0407227 |
| ENO1 | enolase 1, (alpha) | -0.040356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0396092 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0390745 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0389406 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0387542 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0386143 |
| RPL37 | ribosomal protein L37 | -0.0384588 |
| RPLP0 | ribosomal protein, large, P0 | -0.0382335 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0379269 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0379046 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0375565 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.037362 |
| RTN4 | reticulon 4 | -0.0372266 |
| AHNAK | AHNAK nucleoprotein | -0.0359341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0358276 |
| RRM2 | ribonucleotide reductase M2 | -0.0350619 |
| DEK | DEK proto-oncogene | -0.0348794 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345724 |
| CENPF | centromere protein F, 350/400kDa | -0.0343489 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0336255 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.033513 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0325929 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0325481 |
| CCND2 | cyclin D2 | -0.0324277 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0323488 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0320362 |
| GNAS | GNAS complex locus | -0.031959 |
| CANX | calnexin | -0.031875 |
| MATR3 | matrin 3 | -0.0318503 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0318045 |
| RPL11 | ribosomal protein L11 | -0.031605 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311779 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0307043 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0306497 |
| RPS24 | ribosomal protein S24 | -0.0305983 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0305163 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0303816 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0303022 |
| ZNF292 | zinc finger protein 292 | -0.0302066 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0297185 |
| RPL19 | ribosomal protein L19 | -0.0295854 |
| KIF5B | kinesin family member 5B | -0.0295327 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0292595 |
| RACK1 | receptor for activated C kinase 1 | -0.0288749 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0288737 |
| ZFR | zinc finger RNA binding protein | -0.0287509 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0287421 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0286679 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0278561 |
| LDHB | lactate dehydrogenase B | -0.0278219 |
| RPL34 | ribosomal protein L34 | -0.027815 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0276243 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0275237 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0275046 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272208 |
| SEPTIN7 | septin 7 | -0.027169 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0268891 |
| ZNF217 | zinc finger protein 217 | -0.0268526 |
| MT2A | metallothionein 2A | -0.0267057 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0265259 |
| TUBB | tubulin, beta class I | -0.0265141 |
| SRP72 | signal recognition particle 72kDa | -0.026232 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0261699 |
| RPS27A | ribosomal protein S27a | -0.0261228 |
| LDHA | lactate dehydrogenase A | -0.0259357 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0258811 |
| DIAPH3 | diaphanous-related formin 3 | -0.025509 |
| PKM | pyruvate kinase, muscle | -0.0254151 |
| SGO2 | shugoshin 2 | -0.0253146 |
