| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.0962395 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0481643 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0464059 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0460841 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0386576 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0365192 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0349888 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0278596 |
| DST | dystonin | 0.0273125 |
| GRAMD1B | GRAM domain containing 1B | 0.0236694 |
| LSAMP | limbic system-associated membrane protein | 0.0229847 |
| RAD51B | RAD51 paralog B | 0.021993 |
| HDAC4 | histone deacetylase 4 | 0.0219245 |
| PRELID2 | PRELI domain containing 2 | 0.0187724 |
| AUTS2 | autism susceptibility candidate 2 | 0.0176265 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0172883 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0166789 |
| AEBP2 | AE binding protein 2 | 0.0166085 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0164959 |
| GPHN | gephyrin | 0.0159272 |
| XPO1 | exportin 1 | 0.0148101 |
| MT2A | metallothionein 2A | 0.0147867 |
| INTS6 | integrator complex subunit 6 | 0.0140188 |
| RNF150 | ring finger protein 150 | 0.0140144 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.0139827 |
| EXOC4 | exocyst complex component 4 | 0.0136663 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0133322 |
| CADM2 | cell adhesion molecule 2 | 0.0130074 |
| PDE7B | phosphodiesterase 7B | 0.0128318 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0121259 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0118862 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0113313 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0110479 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.010287 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0101172 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0100373 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.00986278 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.00985693 |
| FNIP1 | folliculin interacting protein 1 | 0.0097523 |
| WWOX | WW domain containing oxidoreductase | 0.00973891 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.00959745 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.00941939 |
| PCDH15 | protocadherin-related 15 | 0.00917411 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.00901651 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00901252 |
| KIAA0825 | KIAA0825 | 0.00896092 |
| EGFR | epidermal growth factor receptor | 0.00888882 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.00879348 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.00875345 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.00868972 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.00852525 |
| OPHN1 | oligophrenin 1 | 0.00845302 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.00844521 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00839011 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.00811868 |
| PCDH9 | protocadherin 9 | 0.00809912 |
| NGFR | nerve growth factor receptor | 0.00805839 |
| TMEM117 | transmembrane protein 117 | 0.00794939 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0078909 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00784098 |
| PCDH7 | protocadherin 7 | 0.00781374 |
| SUMF1 | sulfatase modifying factor 1 | 0.00780863 |
| TRABD2B | TraB domain containing 2B | 0.00780475 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.00776033 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0077197 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.00770206 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0076798 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.00762932 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.00753297 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.00747085 |
| CPNE1 | copine I | 0.00742907 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | 0.00735983 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0073582 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0073417 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.00733927 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0072594 |
| MACROD2 | MACRO domain containing 2 | 0.00724762 |
| TMEM178B | transmembrane protein 178B | 0.00719317 |
| CCNG2 | cyclin G2 | 0.00702765 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.00701123 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.00699472 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.00699117 |
| FHIT | fragile histidine triad | 0.0069559 |
| STK32A | serine/threonine kinase 32A | 0.00693443 |
| PRKCE | protein kinase C, epsilon | 0.00672506 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.00672053 |
| TENM2 | teneurin transmembrane protein 2 | 0.00670779 |
| DGKI | diacylglycerol kinase, iota | 0.00667887 |
| MAP7 | microtubule-associated protein 7 | 0.00657661 |
| FKTN | fukutin | 0.00652054 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00644558 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00644118 |
| PCBP3 | poly(rC) binding protein 3 | 0.00636462 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.00636147 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00633492 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.006212 |
| GPATCH2 | G patch domain containing 2 | 0.0060902 |
| ACVR1C | activin A receptor, type IC | 0.00603524 |
| GALK2 | galactokinase 2 | 0.00591689 |
| MALT1 | MALT1 paracaspase | 0.00585314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.214307 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.187509 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.170646 |
| FN1 | fibronectin 1 | -0.164055 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.115209 |
| VIM | vimentin | -0.0888547 |
| PTMA | prothymosin, alpha | -0.0853558 |
| SPAG9 | sperm associated antigen 9 | -0.0764555 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0665873 |
| CANX | calnexin | -0.0663185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.06576 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0653722 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0643372 |
| FTL | ferritin, light polypeptide | -0.062938 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0602487 |
| TMSB10 | thymosin beta 10 | -0.0589044 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0548454 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0543203 |
| EFNA5 | ephrin-A5 | -0.0522073 |
| STC1 | stanniocalcin 1 | -0.0512504 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0509474 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0505995 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0494849 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0480723 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0473404 |
| PGK1 | phosphoglycerate kinase 1 | -0.0472469 |
| S100A6 | S100 calcium binding protein A6 | -0.0471508 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0458908 |
| B2M | beta-2-microglobulin | -0.0452649 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0452039 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0447798 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0444868 |
| RPS6 | ribosomal protein S6 | -0.0441874 |
| GDA | guanine deaminase | -0.0441231 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0431999 |
| UBC | ubiquitin C | -0.043166 |
| LDHA | lactate dehydrogenase A | -0.0425305 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0420166 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0416958 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0415479 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0410953 |
| RPLP1 | ribosomal protein, large, P1 | -0.0407826 |
| GNAS | GNAS complex locus | -0.0406916 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0406599 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0404916 |
| ANXA2 | annexin A2 | -0.0403384 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0398909 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0395917 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0388099 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0385288 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0373527 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0371017 |
| RTN4 | reticulon 4 | -0.0357288 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0356349 |
| MCL1 | myeloid cell leukemia 1 | -0.0352815 |
| GOLGA4 | golgin A4 | -0.0347785 |
| ASPH | aspartate beta-hydroxylase | -0.0345777 |
| TXNRD1 | thioredoxin reductase 1 | -0.0345146 |
| RPS24 | ribosomal protein S24 | -0.0343092 |
| RPS8 | ribosomal protein S8 | -0.034162 |
| MORF4L2 | mortality factor 4 like 2 | -0.0340711 |
| RPLP0 | ribosomal protein, large, P0 | -0.033963 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0333321 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330769 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0330488 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0329612 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0326764 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0326022 |
| CD109 | CD109 molecule | -0.0324208 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0323868 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0322333 |
| RBM39 | RNA binding motif protein 39 | -0.0318073 |
| RPL26 | ribosomal protein L26 | -0.0317153 |
| RPL19 | ribosomal protein L19 | -0.0307067 |
| RPL12 | ribosomal protein L12 | -0.0302212 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0301782 |
| S100A10 | S100 calcium binding protein A10 | -0.0300142 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0298666 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0298235 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0293812 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0293122 |
| ABLIM1 | actin binding LIM protein 1 | -0.0290311 |
| BMERB1 | bMERB domain containing 1 | -0.028781 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0287312 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0287252 |
| RACK1 | receptor for activated C kinase 1 | -0.0282775 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0280986 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0279631 |
| WDR45B | WD repeat domain 45B | -0.0279261 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0275634 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273633 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0272851 |
| HLA-A | major histocompatibility complex, class I, A | -0.02718 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0266361 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0265543 |
| COPA | coatomer protein complex, subunit alpha | -0.0265295 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0265274 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0264988 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0264916 |
