| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.132072 |
| DST | dystonin | 0.0984711 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0782227 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0765202 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0764341 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0711465 |
| INTS6 | integrator complex subunit 6 | 0.0684106 |
| PTK2 | protein tyrosine kinase 2 | 0.0663355 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0660131 |
| MT2A | metallothionein 2A | 0.0648326 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0639379 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0624298 |
| XPO1 | exportin 1 | 0.0598227 |
| SLC35F3 | solute carrier family 35, member F3 | 0.059667 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0593637 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0535162 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0528431 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0508576 |
| EXOC4 | exocyst complex component 4 | 0.0507408 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0503222 |
| SMYD3 | SET and MYND domain containing 3 | 0.0500657 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.049837 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0492596 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0483792 |
| HDAC9 | histone deacetylase 9 | 0.048337 |
| UTRN | utrophin | 0.0479462 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0455689 |
| RNF220 | ring finger protein 220 | 0.0455217 |
| SEPTIN9 | septin 9 | 0.0454321 |
| TXNRD1 | thioredoxin reductase 1 | 0.0452283 |
| SQSTM1 | sequestosome 1 | 0.0449997 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0440185 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0430634 |
| AHNAK | AHNAK nucleoprotein | 0.042722 |
| ASPH | aspartate beta-hydroxylase | 0.0424101 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.042322 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0419561 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0409837 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.040305 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0400256 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0394895 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0390574 |
| ZNF780B | zinc finger protein 780B | 0.0385946 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0369924 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0369869 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0363867 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0362184 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0360777 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0357628 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0348628 |
| PKM | pyruvate kinase, muscle | 0.0336855 |
| HDAC8 | histone deacetylase 8 | 0.0334416 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0330863 |
| WWOX | WW domain containing oxidoreductase | 0.0328365 |
| RNF150 | ring finger protein 150 | 0.0327657 |
| NAV2 | neuron navigator 2 | 0.0326811 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0325337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0324274 |
| ERBIN | erbb2 interacting protein | 0.0324204 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0323744 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.032187 |
| DMXL1 | Dmx-like 1 | 0.0320717 |
| RAD51B | RAD51 paralog B | 0.03192 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0316515 |
| PRTG | protogenin | 0.0315709 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0315256 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0314759 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0312521 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0310188 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0309928 |
| WDR27 | WD repeat domain 27 | 0.0309708 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0308468 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0308097 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0308083 |
| EXOC6B | exocyst complex component 6B | 0.0306211 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0304051 |
| FAT1 | FAT atypical cadherin 1 | 0.0302788 |
| NHSL1 | NHS-like 1 | 0.0302778 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0301768 |
| BRD2 | bromodomain containing 2 | 0.0299596 |
| TRIM66 | tripartite motif containing 66 | 0.0298561 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.029632 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0295305 |
| FTL | ferritin, light polypeptide | 0.0294725 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0290937 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0290555 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0289515 |
| VMP1 | vacuole membrane protein 1 | 0.0287473 |
| SMAD3 | SMAD family member 3 | 0.0287053 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0286741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285855 |
| CUX1 | cut-like homeobox 1 | 0.0284885 |
| SATB2 | SATB homeobox 2 | 0.0283878 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.028257 |
| ATXN1 | ataxin 1 | 0.0282535 |
| ATG10 | autophagy related 10 | 0.028233 |
| ZNF638 | zinc finger protein 638 | 0.0281678 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0280406 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0279046 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0278229 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.14562 |
| RPS16 | ribosomal protein S16 | -0.145544 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.12702 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120966 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0940838 |
| FBL | fibrillarin | -0.0906567 |
| SPAG9 | sperm associated antigen 9 | -0.0808084 |
| TMEM123 | transmembrane protein 123 | -0.060207 |
| GOLGA4 | golgin A4 | -0.0586255 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0577771 |
| H1-0 | H1.0 linker histone | -0.0549479 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0541267 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0518165 |
| ATP13A3 | ATPase type 13A3 | -0.0508914 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0507739 |
| CANX | calnexin | -0.0505786 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0503711 |
| RPS24 | ribosomal protein S24 | -0.0502878 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0483143 |
| UBC | ubiquitin C | -0.0469982 |
| VCL | vinculin | -0.0468415 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0460682 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0455804 |
| TMEM41B | transmembrane protein 41B | -0.0455596 |
| S100A6 | S100 calcium binding protein A6 | -0.0453706 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0450413 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0442803 |
| MORF4L2 | mortality factor 4 like 2 | -0.0442575 |
| SNX14 | sorting nexin 14 | -0.0438908 |
| KLF6 | Kruppel-like factor 6 | -0.0435582 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0433661 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0428919 |
| CD44 | CD44 molecule (Indian blood group) | -0.0419253 |
| ANLN | anillin, actin binding protein | -0.0415765 |
| WDR45B | WD repeat domain 45B | -0.0404274 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0391958 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0382314 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0376703 |
| SBF2 | SET binding factor 2 | -0.0371554 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0371088 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0370973 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0366091 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0364729 |
| ACTG1 | actin gamma 1 | -0.0360813 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0357099 |
| CD109 | CD109 molecule | -0.0356719 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0349154 |
| YBX1 | Y box binding protein 1 | -0.0347379 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0343394 |
| SUCO | SUN domain containing ossification factor | -0.033651 |
| SEC24A | SEC24 family member A | -0.0331724 |
| TMSB10 | thymosin beta 10 | -0.0329691 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0326854 |
| ZFP36 | ZFP36 ring finger protein | -0.0326585 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0323039 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319993 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0319246 |
| SRP54 | signal recognition particle 54kDa | -0.0316277 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0311883 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0309911 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0307155 |
| RPLP0 | ribosomal protein, large, P0 | -0.0306367 |
| IPO7 | importin 7 | -0.0306334 |
| RTN4 | reticulon 4 | -0.0300729 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0299502 |
| RASA2 | RAS p21 protein activator 2 | -0.0296595 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0295446 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.029318 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0291997 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0291048 |
| ZNF217 | zinc finger protein 217 | -0.029043 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0290125 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0289728 |
| RPL36A | ribosomal protein L36a | -0.0285207 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0283754 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0282506 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0281683 |
| USP3 | ubiquitin specific peptidase 3 | -0.0279371 |
| CD2AP | CD2-associated protein | -0.0278419 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0275802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274987 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273942 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0272322 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0272067 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0269941 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0269856 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0265555 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265161 |
| CLINT1 | clathrin interactor 1 | -0.0264674 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0260556 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0257002 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0254513 |
| COPA | coatomer protein complex, subunit alpha | -0.0252874 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0250324 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0249999 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0247562 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0246062 |
| NOP58 | NOP58 ribonucleoprotein | -0.0245326 |
| NIPSNAP2 | nipsnap homolog 2 | -0.024193 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.024104 |
