| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0785237 |
| FAT1 | FAT atypical cadherin 1 | 0.070635 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.056587 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0556326 |
| XPO1 | exportin 1 | 0.0530557 |
| HMGA2 | high mobility group AT-hook 2 | 0.0480191 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.047975 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0471895 |
| RNF150 | ring finger protein 150 | 0.0443237 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0432615 |
| EXT1 | exostosin glycosyltransferase 1 | 0.038709 |
| SMAD3 | SMAD family member 3 | 0.0380238 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0377174 |
| LYST | lysosomal trafficking regulator | 0.0355397 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0318376 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312689 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0307593 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0304056 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0299121 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0284581 |
| STK32A | serine/threonine kinase 32A | 0.028339 |
| SVIL | supervillin | 0.0282041 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0275708 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0256889 |
| HDAC9 | histone deacetylase 9 | 0.0253602 |
| DENND4C | DENN/MADD domain containing 4C | 0.0231404 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | 0.0218046 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0214195 |
| SSH2 | slingshot protein phosphatase 2 | 0.0205268 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0204888 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0201606 |
| FHIT | fragile histidine triad | 0.0199094 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0198971 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0196849 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0194379 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0182862 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0182472 |
| SEPTIN9 | septin 9 | 0.0180979 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.018003 |
| NAV2 | neuron navigator 2 | 0.0177468 |
| ARRDC3 | arrestin domain containing 3 | 0.0175861 |
| DMXL1 | Dmx-like 1 | 0.0172941 |
| TNNC1 | troponin C type 1 (slow) | 0.0172378 |
| NGFR | nerve growth factor receptor | 0.0171119 |
| UST | uronyl-2-sulfotransferase | 0.0165095 |
| AOPEP | aminopeptidase O (putative) | 0.0163458 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.0161361 |
| YEATS2 | YEATS domain containing 2 | 0.0159802 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0159309 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0158509 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.015802 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.015476 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0153857 |
| GPHN | gephyrin | 0.015359 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0153202 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0152321 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0152192 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0151724 |
| ZNF609 | zinc finger protein 609 | 0.0148078 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0142143 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0142056 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0139827 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.013875 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0137548 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0136103 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0135697 |
| MSR1 | macrophage scavenger receptor 1 | 0.0134492 |
| SUMF1 | sulfatase modifying factor 1 | 0.0134449 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0134169 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0133695 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0131976 |
| SACS | sacsin molecular chaperone | 0.0131654 |
| OGA | O-GlcNAcase | 0.0131607 |
| CAVIN1 | caveolae associated protein 1 | 0.0130857 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.0129562 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0129462 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0129302 |
| SSH1 | slingshot protein phosphatase 1 | 0.0128907 |
| CBFB | core-binding factor, beta subunit | 0.0128538 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0128445 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0126994 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0123512 |
| PLCG1 | phospholipase C, gamma 1 | 0.0123062 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0123052 |
| ENOSF1 | enolase superfamily member 1 | 0.0122746 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0121941 |
| PRTG | protogenin | 0.0120619 |
| LIMD1 | LIM domains containing 1 | 0.0120372 |
| APP | amyloid beta (A4) precursor protein | 0.0119013 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0118832 |
| ZNF91 | zinc finger protein 91 | 0.0118026 |
| COL5A1 | collagen, type V, alpha 1 | 0.0116192 |
| STARD9 | StAR-related lipid transfer (START) domain containing 9 | 0.0115423 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0115071 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.011449 |
| IGF2 | insulin-like growth factor 2 | 0.0114442 |
| ANXA1 | annexin A1 | 0.0114184 |
| DCP1A | decapping mRNA 1A | 0.0114051 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0113985 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0113556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.249437 |
| VIM | vimentin | -0.134813 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0990249 |
| TMSB10 | thymosin beta 10 | -0.0988355 |
| B2M | beta-2-microglobulin | -0.0929967 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.086172 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0843769 |
| HLA-B | major histocompatibility complex, class I, B | -0.0801496 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0789464 |
| NDRG1 | N-myc downstream regulated 1 | -0.0768461 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0759796 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0738897 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0703852 |
| COL1A1 | collagen, type I, alpha 1 | -0.0684577 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0673291 |
| MT2A | metallothionein 2A | -0.0671735 |
| NAV1 | neuron navigator 1 | -0.0621825 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0613666 |
| ASPH | aspartate beta-hydroxylase | -0.0595766 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0544503 |
| GOLGA4 | golgin A4 | -0.0534353 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0533781 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.051753 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0513844 |
| FTL | ferritin, light polypeptide | -0.0502157 |
| FRMD4A | FERM domain containing 4A | -0.0495314 |
| SP100 | SP100 nuclear antigen | -0.0493047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0488114 |
| TOP1 | topoisomerase (DNA) I | -0.0485461 |
| POTEF | POTE ankyrin domain family, member F | -0.048156 |
| VCL | vinculin | -0.0479594 |
| GLIS3 | GLIS family zinc finger 3 | -0.0476383 |
| IL1B | interleukin 1, beta | -0.0474768 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0474453 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.047426 |
| RPLP1 | ribosomal protein, large, P1 | -0.0470105 |
| RAD51B | RAD51 paralog B | -0.0466995 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0466159 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0462994 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0460501 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0460251 |
| TMEM178B | transmembrane protein 178B | -0.0456552 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0456494 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0439564 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0430258 |
| COL1A2 | collagen, type I, alpha 2 | -0.0425246 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0420522 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0415853 |
| PGK1 | phosphoglycerate kinase 1 | -0.0414286 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0405005 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0392602 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0391818 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0381323 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0372967 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0371794 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0364763 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0363331 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0360713 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0356593 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0350421 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0350411 |
| RPS8 | ribosomal protein S8 | -0.0341917 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0335411 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0334037 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331626 |
| HDLBP | high density lipoprotein binding protein | -0.0328914 |
| RPS12 | ribosomal protein S12 | -0.0324521 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0323615 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0323431 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0323016 |
| RPS6 | ribosomal protein S6 | -0.0320756 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0318706 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0318175 |
| RPS19 | ribosomal protein S19 | -0.0317162 |
| HM13 | histocompatibility (minor) 13 | -0.031546 |
| H1-0 | H1.0 linker histone | -0.0310245 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0310048 |
| RPL23 | ribosomal protein L23 | -0.0308163 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306925 |
| IFI44 | interferon-induced protein 44 | -0.0306827 |
| SEC24D | SEC24 family member D | -0.030632 |
| RRBP1 | ribosome binding protein 1 | -0.0306251 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0304886 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0304581 |
| PKM | pyruvate kinase, muscle | -0.0304444 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0301394 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.029618 |
| TPM1 | tropomyosin 1 (alpha) | -0.0295998 |
| PGM3 | phosphoglucomutase 3 | -0.0293092 |
| CDH13 | cadherin 13 | -0.0292416 |
| GOLGB1 | golgin B1 | -0.0291845 |
| BBX | bobby sox homolog (Drosophila) | -0.0290599 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0282649 |
| INHBA | inhibin, beta A | -0.0281503 |
| TMEM263 | transmembrane protein 263 | -0.0281094 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.02789 |
| MORF4L2 | mortality factor 4 like 2 | -0.0276309 |
| HLA-A | major histocompatibility complex, class I, A | -0.0273432 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0273012 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0272897 |
