| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Selinexor _SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.252189 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.111652 |
| NRG3 | neuregulin 3 | 0.0958293 |
| DST | dystonin | 0.0723529 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0706851 |
| FMN1 | formin 1 | 0.0588471 |
| FRMD4A | FERM domain containing 4A | 0.0561718 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0529595 |
| LSAMP | limbic system-associated membrane protein | 0.0492891 |
| FHIT | fragile histidine triad | 0.0460532 |
| MACROD2 | MACRO domain containing 2 | 0.0442346 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0438093 |
| FRMD5 | FERM domain containing 5 | 0.0428534 |
| ENO1 | enolase 1, (alpha) | 0.0367458 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0366498 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0359868 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0353439 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0353076 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0344443 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0341221 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0336491 |
| LDHA | lactate dehydrogenase A | 0.033492 |
| RUNX1 | runt-related transcription factor 1 | 0.0325442 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0323869 |
| DPP6 | dipeptidyl-peptidase 6 | 0.0321179 |
| TCF12 | transcription factor 12 | 0.0308535 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0304888 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298192 |
| SUMF1 | sulfatase modifying factor 1 | 0.0297303 |
| SFTPA2 | surfactant protein A2 | 0.0296571 |
| NRP2 | neuropilin 2 | 0.0293874 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0291383 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0289055 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0283649 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.028132 |
| HDAC9 | histone deacetylase 9 | 0.0281091 |
| CCND1 | cyclin D1 | 0.027757 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0276511 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0275938 |
| CA8 | carbonic anhydrase VIII | 0.0263264 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0260559 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0259165 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0258208 |
| CDK6 | cyclin-dependent kinase 6 | 0.0257699 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0256652 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0249597 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0249247 |
| BPTF | bromodomain PHD finger transcription factor | 0.0240642 |
| AHNAK | AHNAK nucleoprotein | 0.0235905 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023495 |
| JAK1 | Janus kinase 1 | 0.0229322 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0228363 |
| USP22 | ubiquitin specific peptidase 22 | 0.0227711 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0227437 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0226056 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0224548 |
| ANXA2 | annexin A2 | 0.0222858 |
| XPO1 | exportin 1 | 0.0222658 |
| TASOR | transcription activation suppressor | 0.0222646 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0219169 |
| NLGN1 | neuroligin 1 | 0.0218223 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.021779 |
| UTRN | utrophin | 0.0212536 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0211708 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0211185 |
| MKI67 | marker of proliferation Ki-67 | 0.0210681 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0209076 |
| DMXL1 | Dmx-like 1 | 0.0206996 |
| MBTD1 | mbt domain containing 1 | 0.0205105 |
| PLSCR1 | phospholipid scramblase 1 | 0.0204967 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0200891 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0199846 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.0198342 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0197931 |
| OGA | O-GlcNAcase | 0.0197035 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0196866 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0196746 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0196655 |
| MTAP | methylthioadenosine phosphorylase | 0.0196104 |
| CTSB | cathepsin B | 0.0193303 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0189966 |
| CLTC | clathrin, heavy chain (Hc) | 0.0186693 |
| CYTH3 | cytohesin 3 | 0.0184909 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0184796 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.018254 |
| RAD51B | RAD51 paralog B | 0.0182171 |
| CHSY3 | chondroitin sulfate synthase 3 | 0.0178456 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0177359 |
| FRMD6 | FERM domain containing 6 | 0.0176093 |
| VMP1 | vacuole membrane protein 1 | 0.0174533 |
| PGK1 | phosphoglycerate kinase 1 | 0.017395 |
| STK32A | serine/threonine kinase 32A | 0.0171691 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0170972 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0170706 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0170413 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0167951 |
| PRKD1 | protein kinase D1 | 0.0167214 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0166571 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0166456 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0165351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.137432 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0883705 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0647141 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0596668 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0519933 |
| RPS6 | ribosomal protein S6 | -0.0512112 |
| RPL23 | ribosomal protein L23 | -0.0507766 |
| POTEF | POTE ankyrin domain family, member F | -0.0471432 |
| UBC | ubiquitin C | -0.0466362 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0463393 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0442859 |
| TMSB10 | thymosin beta 10 | -0.0432978 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0419703 |
| MT2A | metallothionein 2A | -0.0416252 |
| GOLGA4 | golgin A4 | -0.0411097 |
| FTL | ferritin, light polypeptide | -0.0401708 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0389544 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.038911 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0359046 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349795 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0348942 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0327458 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0325369 |
| RPS27A | ribosomal protein S27a | -0.0320381 |
| PCBP2 | poly(rC) binding protein 2 | -0.0318374 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.031705 |
| ASPH | aspartate beta-hydroxylase | -0.0312688 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0311785 |
| RPS12 | ribosomal protein S12 | -0.0309935 |
| RPL9 | ribosomal protein L9 | -0.0307404 |
| RCOR1 | REST corepressor 1 | -0.0305251 |
| CABIN1 | calcineurin binding protein 1 | -0.0299345 |
| TFG | TRK-fused gene | -0.0295807 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0287108 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0284373 |
| RPS3 | ribosomal protein S3 | -0.0283428 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.027659 |
| NDRG1 | N-myc downstream regulated 1 | -0.0276469 |
| RPL37A | ribosomal protein L37a | -0.0275348 |
| RPL11 | ribosomal protein L11 | -0.0273889 |
| MYO9B | myosin IXB | -0.0272737 |
| CTBP2 | C-terminal binding protein 2 | -0.0272357 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.027235 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0271574 |
| SPAG9 | sperm associated antigen 9 | -0.0268745 |
| SBF2 | SET binding factor 2 | -0.0266189 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0265708 |
| TPD52 | tumor protein D52 | -0.0262619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0259709 |
| RPS8 | ribosomal protein S8 | -0.0258619 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.025853 |
| GPATCH2L | G patch domain containing 2-like | -0.0257271 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0254028 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.025322 |
| RPL35A | ribosomal protein L35a | -0.0250607 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0248592 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0247864 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0246594 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0242189 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0241088 |
| FLNB | filamin B, beta | -0.0239318 |
| CLIC4 | chloride intracellular channel 4 | -0.0238382 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0237234 |
| MSI2 | musashi RNA-binding protein 2 | -0.0236273 |
| ACTN4 | actinin, alpha 4 | -0.0234265 |
| RPS19 | ribosomal protein S19 | -0.0233332 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0232884 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0232852 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0232578 |
| RPL12 | ribosomal protein L12 | -0.0228665 |
| HM13 | histocompatibility (minor) 13 | -0.0226518 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0224874 |
| ATF4 | activating transcription factor 4 | -0.0224345 |
| SEPTIN9 | septin 9 | -0.0223408 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.022337 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0222812 |
| NOTCH2 | notch 2 | -0.0222246 |
| COPA | coatomer protein complex, subunit alpha | -0.0220375 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0219801 |
| S100A9 | S100 calcium binding protein A9 | -0.0219579 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0217936 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0217016 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0214964 |
| RPL5 | ribosomal protein L5 | -0.0214787 |
| RPL19 | ribosomal protein L19 | -0.0212075 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0211247 |
| RPL31 | ribosomal protein L31 | -0.0209966 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.020794 |
| RPS21 | ribosomal protein S21 | -0.0204203 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0203713 |
| RBM25 | RNA binding motif protein 25 | -0.0203135 |
| CD44 | CD44 molecule (Indian blood group) | -0.0201584 |
| RPL36 | ribosomal protein L36 | -0.0201443 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0200652 |
| RPS23 | ribosomal protein S23 | -0.0200092 |
| TJP1 | tight junction protein 1 | -0.0199843 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0199648 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0199025 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0196532 |
| RPS13 | ribosomal protein S13 | -0.0196177 |
