| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.179238 |
| VCL | vinculin | 0.176513 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.104977 |
| XPO1 | exportin 1 | 0.084289 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0799522 |
| PDGFC | platelet derived growth factor C | 0.0703687 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0619659 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0566399 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0533044 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.053263 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.051877 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0495699 |
| MEF2A | myocyte enhancer factor 2A | 0.0494091 |
| ZNF608 | zinc finger protein 608 | 0.0492108 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0487026 |
| ANXA1 | annexin A1 | 0.0478031 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.04776 |
| SQSTM1 | sequestosome 1 | 0.045959 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0448524 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0446316 |
| CCNL1 | cyclin L1 | 0.0443332 |
| B2M | beta-2-microglobulin | 0.0441658 |
| TPM4 | tropomyosin 4 | 0.0440693 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.044063 |
| ANK2 | ankyrin 2, neuronal | 0.042611 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0412004 |
| PLPP3 | phospholipid phosphatase 3 | 0.0407548 |
| EZR | ezrin | 0.0388585 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0383527 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0377421 |
| DGKH | diacylglycerol kinase, eta | 0.0370948 |
| OGA | O-GlcNAcase | 0.0369116 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0347547 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0347074 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0340356 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0333468 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0324708 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0323257 |
| DSTN | destrin (actin depolymerizing factor) | 0.0319962 |
| PRTG | protogenin | 0.0317563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0314804 |
| CORO1C | coronin, actin binding protein, 1C | 0.0314512 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.031362 |
| GOLGA4 | golgin A4 | 0.0305122 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0303852 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0303395 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0299413 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0288713 |
| NCOA3 | nuclear receptor coactivator 3 | 0.028529 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0279983 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0279651 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0277239 |
| ANO10 | anoctamin 10 | 0.0276378 |
| TXNIP | thioredoxin interacting protein | 0.0275133 |
| YTHDC1 | YTH domain containing 1 | 0.0270116 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0268426 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0267187 |
| DAPK3 | death-associated protein kinase 3 | 0.0264845 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262472 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.026067 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0260207 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0258858 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0257381 |
| RPL3 | ribosomal protein L3 | 0.0257045 |
| GATA6 | GATA binding protein 6 | 0.0255729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0255638 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0255011 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0254308 |
| DMXL1 | Dmx-like 1 | 0.0249445 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0246329 |
| HDGF | hepatoma-derived growth factor | 0.0246134 |
| ZNF292 | zinc finger protein 292 | 0.0245 |
| EGFR | epidermal growth factor receptor | 0.0243637 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0241606 |
| NUP153 | nucleoporin 153kDa | 0.0240466 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.023946 |
| PAPOLA | poly(A) polymerase alpha | 0.023854 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0238181 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0235226 |
| TRIM24 | tripartite motif containing 24 | 0.0234408 |
| STX8 | syntaxin 8 | 0.0234315 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0232016 |
| SPPL3 | signal peptide peptidase like 3 | 0.0229944 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0227501 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0226804 |
| FOXP1 | forkhead box P1 | 0.0226298 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0222116 |
| PTEN | phosphatase and tensin homolog | 0.0221269 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0220991 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0220067 |
| PLK2 | polo-like kinase 2 | 0.0218596 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0218464 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0218235 |
| MED13L | mediator complex subunit 13-like | 0.0217999 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0215998 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0214306 |
| LDHA | lactate dehydrogenase A | 0.0207708 |
| TFG | TRK-fused gene | 0.020728 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.020309 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0202017 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.119638 |
| AHNAK | AHNAK nucleoprotein | -0.110673 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.102288 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0997739 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0905491 |
| NAV2 | neuron navigator 2 | -0.0808144 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0804757 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0790587 |
| FLNB | filamin B, beta | -0.0786556 |
| DIAPH3 | diaphanous-related formin 3 | -0.0780473 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.076808 |
| CCND1 | cyclin D1 | -0.0737696 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0737324 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0724975 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0715331 |
| PTMA | prothymosin, alpha | -0.069448 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0683253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0677608 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0627651 |
| TJP1 | tight junction protein 1 | -0.0626434 |
| MKI67 | marker of proliferation Ki-67 | -0.0608439 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0607752 |
| GLI3 | GLI family zinc finger 3 | -0.0606986 |
| NFIA | nuclear factor I/A | -0.0579731 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.057772 |
| RPS6 | ribosomal protein S6 | -0.0551 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0528132 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0527998 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0510747 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0507111 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0506696 |
| PRELID2 | PRELI domain containing 2 | -0.0503633 |
| ZNF438 | zinc finger protein 438 | -0.0501818 |
| RRBP1 | ribosome binding protein 1 | -0.0500902 |
| RPLP0 | ribosomal protein, large, P0 | -0.0474471 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.045768 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0444653 |
| DENND1A | DENN/MADD domain containing 1A | -0.043595 |
| GLI2 | GLI family zinc finger 2 | -0.0435758 |
| CENPF | centromere protein F, 350/400kDa | -0.042752 |
| DOCK1 | dedicator of cytokinesis 1 | -0.042627 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0425264 |
| RPL35A | ribosomal protein L35a | -0.0424966 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0423484 |
| MYO5C | myosin VC | -0.0416988 |
| CENPE | centromere protein E, 312kDa | -0.0413879 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0410388 |
| SMYD3 | SET and MYND domain containing 3 | -0.0409754 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.040771 |
| CUX1 | cut-like homeobox 1 | -0.0407001 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402131 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0400849 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0399744 |
| HJURP | Holliday junction recognition protein | -0.039469 |
| RRM2 | ribonucleotide reductase M2 | -0.0391108 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0382603 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0379699 |
| DIAPH2 | diaphanous-related formin 2 | -0.0377213 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0377096 |
| RPS8 | ribosomal protein S8 | -0.0374379 |
| RPL37A | ribosomal protein L37a | -0.0371474 |
| ECT2 | epithelial cell transforming 2 | -0.0369631 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0359385 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0354745 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0353445 |
| RPL26 | ribosomal protein L26 | -0.0350805 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0343903 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0342484 |
| GNAS | GNAS complex locus | -0.0337908 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0336787 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336717 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0334369 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0332893 |
| CKAP5 | cytoskeleton associated protein 5 | -0.03293 |
| BCOR | BCL6 corepressor | -0.032699 |
| BPTF | bromodomain PHD finger transcription factor | -0.0325801 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.032532 |
| MSI2 | musashi RNA-binding protein 2 | -0.032157 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0320885 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0320695 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0316027 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0315815 |
| PSPC1 | paraspeckle component 1 | -0.0314249 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0311384 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0307575 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0304935 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0304917 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0303758 |
| RPL34 | ribosomal protein L34 | -0.0301439 |
| ACTG1 | actin gamma 1 | -0.0300794 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0299818 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0296039 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0295697 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0295134 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0294215 |
| RPS19 | ribosomal protein S19 | -0.0291968 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0291621 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0291187 |
| INTS6 | integrator complex subunit 6 | -0.0289097 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0284532 |
