| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.1923 |
| GLIS3 | GLIS family zinc finger 3 | 0.117953 |
| VCAN | versican | 0.100106 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0943013 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0910869 |
| HMGA2 | high mobility group AT-hook 2 | 0.0781252 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0607964 |
| CDH13 | cadherin 13 | 0.0583436 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0559389 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0525551 |
| HDAC9 | histone deacetylase 9 | 0.0519221 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0495269 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0461986 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0453587 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.044329 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0415034 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041173 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0402742 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0398631 |
| COL5A1 | collagen, type V, alpha 1 | 0.0388842 |
| THBS2 | thrombospondin 2 | 0.0387351 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0373021 |
| AHNAK | AHNAK nucleoprotein | 0.036046 |
| CTSB | cathepsin B | 0.0333597 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0313338 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.030721 |
| SYNJ2 | synaptojanin 2 | 0.029519 |
| STC2 | stanniocalcin 2 | 0.0294716 |
| RND3 | Rho family GTPase 3 | 0.028903 |
| STC1 | stanniocalcin 1 | 0.0279036 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0264259 |
| ASPH | aspartate beta-hydroxylase | 0.0261413 |
| CEP112 | centrosomal protein 112kDa | 0.0259512 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0258318 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0254491 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0253406 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0252958 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0251998 |
| CAVIN1 | caveolae associated protein 1 | 0.0243063 |
| CD44 | CD44 molecule (Indian blood group) | 0.0241136 |
| EXT1 | exostosin glycosyltransferase 1 | 0.024098 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0238881 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0234944 |
| EXOC4 | exocyst complex component 4 | 0.023389 |
| HLA-E | major histocompatibility complex, class I, E | 0.0229504 |
| FRMD4A | FERM domain containing 4A | 0.0221769 |
| VEGFA | vascular endothelial growth factor A | 0.0221114 |
| VMP1 | vacuole membrane protein 1 | 0.0220427 |
| AFAP1 | actin filament associated protein 1 | 0.0216193 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0215533 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | 0.0213894 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0213161 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0209132 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0208341 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0204891 |
| WDR27 | WD repeat domain 27 | 0.0202718 |
| MLPH | melanophilin | 0.0201454 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0199136 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.019447 |
| SMAD3 | SMAD family member 3 | 0.019308 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0192811 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0190433 |
| NRP1 | neuropilin 1 | 0.018613 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0185879 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.018497 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0184717 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0184482 |
| MSN | moesin | 0.0183474 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0182843 |
| DNER | delta/notch-like EGF repeat containing | 0.0182464 |
| SEPTIN9 | septin 9 | 0.0180483 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0176148 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0175751 |
| CANX | calnexin | 0.017561 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0175259 |
| TMSB4X | thymosin beta 4, X-linked | 0.0169849 |
| MMP12 | matrix metallopeptidase 12 | 0.016817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0167326 |
| DST | dystonin | 0.0165621 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0165189 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0164101 |
| EGFR | epidermal growth factor receptor | 0.0163487 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0160557 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0159531 |
| RNF150 | ring finger protein 150 | 0.0157393 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 | 0.015557 |
| RAI14 | retinoic acid induced 14 | 0.0155342 |
| COL6A2 | collagen, type VI, alpha 2 | 0.015346 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0152841 |
| NAV1 | neuron navigator 1 | 0.0151583 |
| FRMD6 | FERM domain containing 6 | 0.0150483 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0150308 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0145992 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0145634 |
| APP | amyloid beta (A4) precursor protein | 0.0144628 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 0.0144614 |
| SLFN5 | schlafen family member 5 | 0.01446 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0143351 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0143246 |
| ATM | ATM serine/threonine kinase | 0.0142512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224282 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.118752 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.117021 |
| VIM | vimentin | -0.10934 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.108896 |
| FTL | ferritin, light polypeptide | -0.0982632 |
| CADM1 | cell adhesion molecule 1 | -0.09757 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0958663 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0957901 |
| ADM | adrenomedullin | -0.0953694 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0934285 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0919997 |
| MT2A | metallothionein 2A | -0.0918649 |
| IER3 | immediate early response 3 | -0.0843166 |
| TMSB10 | thymosin beta 10 | -0.0835962 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.082731 |
| ZNF292 | zinc finger protein 292 | -0.0824727 |
| UBC | ubiquitin C | -0.0747327 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0703703 |
| RPS6 | ribosomal protein S6 | -0.0694356 |
| PGK1 | phosphoglycerate kinase 1 | -0.0684139 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0683784 |
| PTMA | prothymosin, alpha | -0.0679384 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0667377 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0644189 |
| NAV2 | neuron navigator 2 | -0.0640229 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0640206 |
| SPAG9 | sperm associated antigen 9 | -0.063991 |
| HLA-B | major histocompatibility complex, class I, B | -0.0627705 |
| RPL23 | ribosomal protein L23 | -0.062549 |
| RPS12 | ribosomal protein S12 | -0.0612833 |
| GOLGA4 | golgin A4 | -0.0577726 |
| TSC22D2 | TSC22 domain family, member 2 | -0.057125 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0537289 |
| ATP13A3 | ATPase type 13A3 | -0.0534348 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.052204 |
| WTAP | Wilms tumor 1 associated protein | -0.0517751 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0517635 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0512411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0508526 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0507239 |
| PHIP | pleckstrin homology domain interacting protein | -0.049874 |
| QKI | QKI, KH domain containing, RNA binding | -0.0489791 |
| PCBP2 | poly(rC) binding protein 2 | -0.0483366 |
| OGA | O-GlcNAcase | -0.0481364 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0478588 |
| SETD5 | SET domain containing 5 | -0.0468073 |
| RPS24 | ribosomal protein S24 | -0.0465123 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0462893 |
| ANXA2 | annexin A2 | -0.0458461 |
| RPS3 | ribosomal protein S3 | -0.0455199 |
| RPS27A | ribosomal protein S27a | -0.044793 |
| CENPF | centromere protein F, 350/400kDa | -0.0447647 |
| RTN4 | reticulon 4 | -0.0443637 |
| TXNIP | thioredoxin interacting protein | -0.0441588 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0440679 |
| CCNL1 | cyclin L1 | -0.0440559 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0436906 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.043674 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0431144 |
| VCL | vinculin | -0.0428411 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0423501 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0418917 |
| RPL35A | ribosomal protein L35a | -0.041845 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0417916 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0416355 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0413687 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0409977 |
| RACK1 | receptor for activated C kinase 1 | -0.0407296 |
| FLNB | filamin B, beta | -0.0405474 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0394108 |
| ENO1 | enolase 1, (alpha) | -0.0393393 |
| RPS8 | ribosomal protein S8 | -0.0392032 |
| RPLP2 | ribosomal protein, large, P2 | -0.0383805 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0375039 |
| WDR45B | WD repeat domain 45B | -0.0372145 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0370323 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0367684 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0365912 |
| HELZ | helicase with zinc finger | -0.036118 |
| DEK | DEK proto-oncogene | -0.0357711 |
| RPL9 | ribosomal protein L9 | -0.0357421 |
| RPL12 | ribosomal protein L12 | -0.0357299 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0355588 |
| SBF2 | SET binding factor 2 | -0.0354671 |
| RPS23 | ribosomal protein S23 | -0.0354476 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0350746 |
| B2M | beta-2-microglobulin | -0.0348188 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0347665 |
| RPL11 | ribosomal protein L11 | -0.0344875 |
| RPL37A | ribosomal protein L37a | -0.0341798 |
| RPS4X | ribosomal protein S4, X-linked | -0.0341495 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0335011 |
| RPLP0 | ribosomal protein, large, P0 | -0.0330107 |
| ANLN | anillin, actin binding protein | -0.0329934 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0329577 |
| WAC | WW domain containing adaptor with coiled-coil | -0.03295 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0328159 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0327489 |
| RBM39 | RNA binding motif protein 39 | -0.0326953 |
