| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.211713 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.139065 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112732 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.112552 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0865418 |
| FAM13A | family with sequence similarity 13, member A | 0.0741603 |
| COL5A1 | collagen, type V, alpha 1 | 0.0731239 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0685548 |
| AHNAK | AHNAK nucleoprotein | 0.0658438 |
| LOXL2 | lysyl oxidase-like 2 | 0.056102 |
| CANX | calnexin | 0.0545888 |
| NDRG1 | N-myc downstream regulated 1 | 0.0545019 |
| FN1 | fibronectin 1 | 0.0529824 |
| ARRDC3 | arrestin domain containing 3 | 0.0528109 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0519975 |
| SDC4 | syndecan 4 | 0.0479995 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0447533 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0407758 |
| ANO6 | anoctamin 6 | 0.0406497 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0397663 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.039713 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.037847 |
| PRELID2 | PRELI domain containing 2 | 0.0364913 |
| HDAC9 | histone deacetylase 9 | 0.0355869 |
| XPO1 | exportin 1 | 0.0353047 |
| RND3 | Rho family GTPase 3 | 0.0345622 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333025 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0330124 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0329679 |
| ZNF395 | zinc finger protein 395 | 0.0317028 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0313021 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0306385 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.029556 |
| CALR | calreticulin | 0.0294363 |
| GSE1 | Gse1 coiled-coil protein | 0.0285412 |
| ANXA2 | annexin A2 | 0.0284723 |
| OGA | O-GlcNAcase | 0.0283017 |
| STC2 | stanniocalcin 2 | 0.0279408 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0278127 |
| TBC1D23 | TBC1 domain family, member 23 | 0.027037 |
| BPTF | bromodomain PHD finger transcription factor | 0.0269095 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0267125 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0266534 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0262843 |
| GOLGA4 | golgin A4 | 0.0259791 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0259236 |
| RASA3 | RAS p21 protein activator 3 | 0.0254483 |
| TMF1 | TATA element modulatory factor 1 | 0.0250954 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0250935 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0248235 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0247807 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0245041 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0244623 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0243761 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0243675 |
| C1D | C1D nuclear receptor corepressor | 0.0243591 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0242718 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0242367 |
| CTSB | cathepsin B | 0.0239978 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0239342 |
| SMYD3 | SET and MYND domain containing 3 | 0.023729 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0236174 |
| DYM | dymeclin | 0.0231316 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0230278 |
| MEF2A | myocyte enhancer factor 2A | 0.0228701 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0228583 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0227557 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0227555 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0226634 |
| AOPEP | aminopeptidase O (putative) | 0.0226047 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0225844 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0220876 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0220357 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0218399 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.0218325 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0218302 |
| YEATS2 | YEATS domain containing 2 | 0.0216824 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0214838 |
| DST | dystonin | 0.0210609 |
| HIP1 | huntingtin interacting protein 1 | 0.020615 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.020396 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0203855 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0202708 |
| VEGFC | vascular endothelial growth factor C | 0.0202584 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0201451 |
| NOTCH2 | notch 2 | 0.0199994 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0199584 |
| FTO | fat mass and obesity associated | 0.0198871 |
| MMP12 | matrix metallopeptidase 12 | 0.0196547 |
| RNF169 | ring finger protein 169 | 0.0196424 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0195446 |
| SDC2 | syndecan 2 | 0.0195165 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0194922 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0194487 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0190841 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0189649 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0186579 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0184651 |
| PGM3 | phosphoglucomutase 3 | 0.01841 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0183421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.20709 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1745 |
| HLA-B | major histocompatibility complex, class I, B | -0.0999007 |
| TMSB10 | thymosin beta 10 | -0.0964207 |
| B2M | beta-2-microglobulin | -0.082363 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0772208 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0670783 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0539359 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0510449 |
| PTMA | prothymosin, alpha | -0.0502532 |
| MT1X | metallothionein 1X | -0.0497941 |
| FTL | ferritin, light polypeptide | -0.0486272 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0456537 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0443884 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0438668 |
| POTEF | POTE ankyrin domain family, member F | -0.0432177 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0427232 |
| SPAG9 | sperm associated antigen 9 | -0.040642 |
| RPL35A | ribosomal protein L35a | -0.0393484 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0389617 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0383667 |
| RPS6 | ribosomal protein S6 | -0.0383338 |
| RPL11 | ribosomal protein L11 | -0.0374975 |
| USP34 | ubiquitin specific peptidase 34 | -0.0372279 |
| HLA-A | major histocompatibility complex, class I, A | -0.0370891 |
| EGR1 | early growth response 1 | -0.0369728 |
| VIM | vimentin | -0.0365218 |
| RPS19 | ribosomal protein S19 | -0.0364713 |
| RPLP1 | ribosomal protein, large, P1 | -0.036372 |
| ACTG1 | actin gamma 1 | -0.0343812 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0343573 |
| RPL23 | ribosomal protein L23 | -0.0339374 |
| RPS8 | ribosomal protein S8 | -0.0336826 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.033353 |
| S100A10 | S100 calcium binding protein A10 | -0.0328221 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0327202 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0321605 |
| ATP13A3 | ATPase type 13A3 | -0.0318 |
| H3-3B | H3.3 histone B | -0.0314529 |
| PKM | pyruvate kinase, muscle | -0.0313444 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0305152 |
| S100A6 | S100 calcium binding protein A6 | -0.0304916 |
| INHBA | inhibin, beta A | -0.0303234 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0303005 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0302863 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0301638 |
| RPS16 | ribosomal protein S16 | -0.0298571 |
| RPL28 | ribosomal protein L28 | -0.0297521 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.029605 |
| RPL19 | ribosomal protein L19 | -0.0292947 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0287409 |
| RPL31 | ribosomal protein L31 | -0.0285794 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0284584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0282921 |
| RPL12 | ribosomal protein L12 | -0.0279801 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0278597 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0277828 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0275044 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0271796 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0270168 |
| COL1A2 | collagen, type I, alpha 2 | -0.0269889 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0268355 |
| RPL36 | ribosomal protein L36 | -0.0267989 |
| RPS12 | ribosomal protein S12 | -0.0267237 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0266094 |
| QKI | QKI, KH domain containing, RNA binding | -0.0262459 |
| RPL7 | ribosomal protein L7 | -0.0259972 |
| CCNI | cyclin I | -0.0259733 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0258146 |
| JAK1 | Janus kinase 1 | -0.0258057 |
| WAC | WW domain containing adaptor with coiled-coil | -0.02568 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0256422 |
| IL6 | interleukin 6 | -0.0255385 |
| TPM1 | tropomyosin 1 (alpha) | -0.0251875 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.025118 |
| USP12 | ubiquitin specific peptidase 12 | -0.0250377 |
| FBXO11 | F-box protein 11 | -0.0250116 |
| TNS3 | tensin 3 | -0.0249343 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0248484 |
| PFN1 | profilin 1 | -0.0248211 |
| SEPTIN7 | septin 7 | -0.0247877 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0247341 |
| VCL | vinculin | -0.0247217 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0243853 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242179 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0241721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0240239 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0239731 |
| RPL34 | ribosomal protein L34 | -0.0238617 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0235768 |
| STC1 | stanniocalcin 1 | -0.0234972 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0233962 |
| NUP58 | nucleoporin 58 | -0.0230476 |
| RPL18 | ribosomal protein L18 | -0.0230202 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0230144 |
| RPL7A | ribosomal protein L7a | -0.0225282 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0224045 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0223503 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0222498 |
| RPL36A | ribosomal protein L36a | -0.0222104 |
