| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Selinexor _SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.111461 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.086033 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0702313 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0675364 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0674082 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0631211 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0619677 |
| EXOC4 | exocyst complex component 4 | 0.0616344 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0494849 |
| CLDN1 | claudin 1 | 0.0476118 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0441748 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0430915 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0428458 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0427914 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0426489 |
| INTS6 | integrator complex subunit 6 | 0.040313 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0396057 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0394504 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0390105 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0386488 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0383422 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0381299 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0368884 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0367097 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0356838 |
| RAD51B | RAD51 paralog B | 0.0354153 |
| EGFR | epidermal growth factor receptor | 0.0345655 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0344423 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.033898 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0338289 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0332046 |
| CORO1C | coronin, actin binding protein, 1C | 0.032825 |
| CYTH1 | cytohesin 1 | 0.0327748 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0327623 |
| ATG10 | autophagy related 10 | 0.0324409 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0321736 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.031741 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0315492 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0315067 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0310127 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0309177 |
| ITGAV | integrin, alpha V | 0.0308006 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.030749 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0305487 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0303878 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0300183 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.0294194 |
| DST | dystonin | 0.0293882 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0293781 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0292893 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0292124 |
| DCP1A | decapping mRNA 1A | 0.0288795 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0284432 |
| GSN | gelsolin | 0.0283091 |
| PHF3 | PHD finger protein 3 | 0.0281724 |
| ZNF609 | zinc finger protein 609 | 0.0281693 |
| STK32A | serine/threonine kinase 32A | 0.0280949 |
| AOPEP | aminopeptidase O (putative) | 0.0280411 |
| FTO | fat mass and obesity associated | 0.0279797 |
| ZC4H2 | zinc finger, C4H2 domain containing | 0.0276264 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.027586 |
| GPC5 | glypican 5 | 0.0274582 |
| ATP9B | ATPase, class II, type 9B | 0.0273637 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0270013 |
| SVIL | supervillin | 0.0269103 |
| AEBP2 | AE binding protein 2 | 0.0267529 |
| JMJD1C | jumonji domain containing 1C | 0.0266779 |
| ANXA1 | annexin A1 | 0.026604 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0263305 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0262658 |
| WDR1 | WD repeat domain 1 | 0.0259773 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0258327 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0258175 |
| TRAM2 | translocation associated membrane protein 2 | 0.0258157 |
| RNF150 | ring finger protein 150 | 0.0256463 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0256199 |
| ZCWPW2 | zinc finger, CW type with PWWP domain 2 | 0.025332 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0251493 |
| ETNK1 | ethanolamine kinase 1 | 0.0250542 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0250065 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0249995 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0249808 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0249683 |
| PCDH7 | protocadherin 7 | 0.0249657 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0244941 |
| CFAP20DC | CFAP20 domain containing | 0.0242874 |
| ARRDC3 | arrestin domain containing 3 | 0.0241218 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0240548 |
| FRMD6 | FERM domain containing 6 | 0.0239876 |
| NHSL1 | NHS-like 1 | 0.0238908 |
| ETV6 | ets variant 6 | 0.0238061 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0237209 |
| ATXN10 | ataxin 10 | 0.0236404 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0236006 |
| NEGR1 | neuronal growth regulator 1 | 0.0235142 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0233907 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0233484 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0233072 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0233014 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0232935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162709 |
| GOLGA4 | golgin A4 | -0.114118 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0806111 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0723791 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0719493 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.066176 |
| CD44 | CD44 molecule (Indian blood group) | -0.064701 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0619324 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0618478 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0613069 |
| RBM39 | RNA binding motif protein 39 | -0.0593784 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0566437 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.053855 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0537843 |
| SETD5 | SET domain containing 5 | -0.0534754 |
| PRELID2 | PRELI domain containing 2 | -0.0531192 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0530093 |
| NKTR | natural killer cell triggering receptor | -0.0527961 |
| SNX14 | sorting nexin 14 | -0.051857 |
| RIGI | RNA sensor RIG-I | -0.0500561 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.049469 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0480354 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0474133 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0465946 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0462924 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0457265 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0454602 |
| NAV2 | neuron navigator 2 | -0.0446303 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0442553 |
| SPAG9 | sperm associated antigen 9 | -0.0441102 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0440675 |
| PCBP2 | poly(rC) binding protein 2 | -0.0438201 |
| HMGA2 | high mobility group AT-hook 2 | -0.0437923 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.043602 |
| RPS6 | ribosomal protein S6 | -0.0423752 |
| ZNF207 | zinc finger protein 207 | -0.042125 |
| YBX3 | Y box binding protein 3 | -0.0418312 |
| RPS12 | ribosomal protein S12 | -0.0409342 |
| MSN | moesin | -0.0408829 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0405131 |
| GOLGB1 | golgin B1 | -0.040295 |
| CENPF | centromere protein F, 350/400kDa | -0.0401877 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0401507 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0393413 |
| RPL23 | ribosomal protein L23 | -0.0390673 |
| CALU | calumenin | -0.0386064 |
| CEP250 | centrosomal protein 250kDa | -0.0383057 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0381951 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0374908 |
| FBXO11 | F-box protein 11 | -0.0372643 |
| PTMA | prothymosin, alpha | -0.0370816 |
| OGA | O-GlcNAcase | -0.0369083 |
| RPL36 | ribosomal protein L36 | -0.0366937 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.036536 |
| ZNF292 | zinc finger protein 292 | -0.0361129 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0356673 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356491 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0352088 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0351983 |
| RPS13 | ribosomal protein S13 | -0.0349077 |
| CCNL1 | cyclin L1 | -0.0348657 |
| CEP170 | centrosomal protein 170kDa | -0.0348392 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0347155 |
| RPL26 | ribosomal protein L26 | -0.0345551 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0341278 |
| SMYD3 | SET and MYND domain containing 3 | -0.0340836 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0340671 |
| CEP57 | centrosomal protein 57kDa | -0.0340233 |
| RPL19 | ribosomal protein L19 | -0.0338684 |
| GNAS | GNAS complex locus | -0.033412 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0332082 |
| TPR | translocated promoter region, nuclear basket protein | -0.0330977 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0329491 |
| CAPRIN2 | caprin family member 2 | -0.0327358 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0327203 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0318868 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0318114 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0318098 |
| TPX2 | TPX2, microtubule-associated | -0.0317475 |
| QKI | QKI, KH domain containing, RNA binding | -0.0316455 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.031502 |
| RPS17 | ribosomal protein S17 | -0.0314143 |
| HELZ | helicase with zinc finger | -0.0312995 |
| KIAA1328 | KIAA1328 | -0.0309922 |
| PTGES2 | prostaglandin E synthase 2 | -0.0308953 |
| RPL12 | ribosomal protein L12 | -0.0308935 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0307466 |
| KLHL24 | kelch-like family member 24 | -0.0302508 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0301881 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0299134 |
| FNIP1 | folliculin interacting protein 1 | -0.0299018 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0298414 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.029812 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0297373 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0296223 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0295744 |
| TMEM87A | transmembrane protein 87A | -0.0295467 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0294124 |
| PTK2 | protein tyrosine kinase 2 | -0.0293711 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0290945 |
