| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.0558455 |
| ANKRD28 | ankyrin repeat domain 28 | 0.04862 |
| XPO1 | exportin 1 | 0.0481936 |
| TXNRD1 | thioredoxin reductase 1 | 0.0386168 |
| TMEM156 | transmembrane protein 156 | 0.0382741 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0344748 |
| OGA | O-GlcNAcase | 0.0340646 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0313463 |
| STC2 | stanniocalcin 2 | 0.0307227 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0262134 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.026086 |
| CCNG2 | cyclin G2 | 0.0260305 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0242543 |
| LMNA | lamin A/C | 0.0240877 |
| EMP1 | epithelial membrane protein 1 | 0.023365 |
| SVIL | supervillin | 0.0223504 |
| TXNIP | thioredoxin interacting protein | 0.0215889 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0214245 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0211001 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.020683 |
| SIRT1 | sirtuin 1 | 0.0193651 |
| RNF150 | ring finger protein 150 | 0.0187034 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0184425 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0177606 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0177242 |
| YBX3 | Y box binding protein 3 | 0.0172712 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0170097 |
| FAT1 | FAT atypical cadherin 1 | 0.0170072 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0169226 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0165476 |
| MTMR3 | myotubularin related protein 3 | 0.01624 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0161432 |
| SGMS2 | sphingomyelin synthase 2 | 0.0159216 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0153466 |
| NOP58 | NOP58 ribonucleoprotein | 0.0152321 |
| NEK7 | NIMA-related kinase 7 | 0.0149865 |
| KLHDC10 | kelch domain containing 10 | 0.0149603 |
| WDR26 | WD repeat domain 26 | 0.0149545 |
| APP | amyloid beta (A4) precursor protein | 0.0149377 |
| RND3 | Rho family GTPase 3 | 0.0147677 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0146384 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0145173 |
| RYBP | RING1 and YY1 binding protein | 0.0144355 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0144014 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0142854 |
| NGFR | nerve growth factor receptor | 0.013832 |
| EREG | epiregulin | 0.0137245 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0132986 |
| WDR45B | WD repeat domain 45B | 0.0132765 |
| ARRDC3 | arrestin domain containing 3 | 0.0130752 |
| VEGFA | vascular endothelial growth factor A | 0.0129447 |
| ATF3 | activating transcription factor 3 | 0.0129303 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.012889 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0127284 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0127106 |
| EZR | ezrin | 0.0126129 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0125232 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0123526 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0122452 |
| PCDH7 | protocadherin 7 | 0.0121607 |
| IRS2 | insulin receptor substrate 2 | 0.012085 |
| ETV1 | ets variant 1 | 0.0120484 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0120404 |
| DENND4C | DENN/MADD domain containing 4C | 0.0119617 |
| ZNF608 | zinc finger protein 608 | 0.0119578 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0118921 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.011838 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0117883 |
| BICC1 | BicC family RNA binding protein 1 | 0.0117567 |
| AHR | aryl hydrocarbon receptor | 0.0117088 |
| SRPK2 | SRSF protein kinase 2 | 0.0115978 |
| YME1L1 | YME1-like 1 ATPase | 0.0115216 |
| HLA-E | major histocompatibility complex, class I, E | 0.0112148 |
| ATOSA | atos homolog A | 0.0111971 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0111967 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0111403 |
| RNF145 | ring finger protein 145 | 0.0111199 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0111062 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0109577 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.010874 |
| MYO10 | myosin X | 0.0108641 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0108369 |
| UBL3 | ubiquitin-like 3 | 0.0108108 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.0105008 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0104377 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0104164 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0103305 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0102662 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0101977 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0101816 |
| MYO1B | myosin IB | 0.0101686 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0100705 |
| IDS | iduronate 2-sulfatase | 0.0100635 |
| JMJD1C | jumonji domain containing 1C | 0.0100425 |
| FOXP1 | forkhead box P1 | 0.0100204 |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.0100059 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.00990408 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.00985315 |
| ANAPC1 | anaphase promoting complex subunit 1 | 0.00983618 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00974655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.316788 |
| FN1 | fibronectin 1 | -0.223143 |
| ASPH | aspartate beta-hydroxylase | -0.147982 |
| HMGA2 | high mobility group AT-hook 2 | -0.114422 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.1142 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.108827 |
| VCL | vinculin | -0.108149 |
| EFNA5 | ephrin-A5 | -0.0962977 |
| HLA-B | major histocompatibility complex, class I, B | -0.0856861 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0846181 |
| ITGA1 | integrin, alpha 1 | -0.0784222 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0769064 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0757393 |
| SQSTM1 | sequestosome 1 | -0.0696647 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0681681 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0681263 |
| RAI14 | retinoic acid induced 14 | -0.0656574 |
| TMSB10 | thymosin beta 10 | -0.0643483 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.063523 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0604108 |
| CANX | calnexin | -0.0592617 |
| GLIS3 | GLIS family zinc finger 3 | -0.0589412 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0585939 |
| INTS6 | integrator complex subunit 6 | -0.0546154 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0521609 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0518265 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.051492 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0507232 |
| NDRG1 | N-myc downstream regulated 1 | -0.050319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497087 |
| CADM1 | cell adhesion molecule 1 | -0.0495302 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0469178 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.046782 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0467127 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0445001 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.043661 |
| ACTG1 | actin gamma 1 | -0.0435215 |
| TMSB4X | thymosin beta 4, X-linked | -0.0429931 |
| LOXL2 | lysyl oxidase-like 2 | -0.0428414 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0426574 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0424261 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0422917 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0416848 |
| SYT1 | synaptotagmin I | -0.0412842 |
| MT2A | metallothionein 2A | -0.0399883 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0395406 |
| GPC6 | glypican 6 | -0.0385853 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0368314 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0360353 |
| LRRC23 | leucine rich repeat containing 23 | -0.0359831 |
| PTK2 | protein tyrosine kinase 2 | -0.035737 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0354264 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0343956 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0343836 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0339694 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0339685 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0336041 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0334471 |
| GPATCH2L | G patch domain containing 2-like | -0.0333475 |
| RAD51B | RAD51 paralog B | -0.0329138 |
| PALLD | palladin, cytoskeletal associated protein | -0.0327983 |
| AEBP2 | AE binding protein 2 | -0.0325661 |
| PLIN2 | perilipin 2 | -0.0317627 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0316393 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0315401 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0313928 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.031075 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0309301 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0302415 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0302063 |
| ETV6 | ets variant 6 | -0.0300052 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0298708 |
| RPS6 | ribosomal protein S6 | -0.029511 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.029213 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0289907 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0287706 |
| PRKCA | protein kinase C, alpha | -0.028536 |
| NAV1 | neuron navigator 1 | -0.0282942 |
| GOLGB1 | golgin B1 | -0.0281764 |
| CTBP2 | C-terminal binding protein 2 | -0.0278748 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0275606 |
| HDLBP | high density lipoprotein binding protein | -0.0275549 |
| EGFR | epidermal growth factor receptor | -0.0275383 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0275047 |
| B2M | beta-2-microglobulin | -0.0272525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271815 |
| CCDC91 | coiled-coil domain containing 91 | -0.0270859 |
| ATG7 | autophagy related 7 | -0.0267589 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0267065 |
| FAM20C | family with sequence similarity 20, member C | -0.0266402 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0265861 |
| CLTC | clathrin, heavy chain (Hc) | -0.026267 |
| ENO1 | enolase 1, (alpha) | -0.0262303 |
| CUX1 | cut-like homeobox 1 | -0.0262231 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0261422 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0260495 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0259915 |
| HPCAL1 | hippocalcin-like 1 | -0.0257408 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0257329 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0256043 |
