| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.145756 |
| FNDC3B | fibronectin type III domain containing 3B | 0.138967 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.135794 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.109145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0849384 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0748984 |
| VCL | vinculin | 0.0747295 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0649175 |
| XPO1 | exportin 1 | 0.0613581 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0592861 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0557479 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0540329 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0517007 |
| NDRG1 | N-myc downstream regulated 1 | 0.0515889 |
| GPHN | gephyrin | 0.0512618 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0500505 |
| PTMA | prothymosin, alpha | 0.0491076 |
| EZR | ezrin | 0.0490497 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0481668 |
| ANO10 | anoctamin 10 | 0.0476414 |
| FAM107B | family with sequence similarity 107, member B | 0.0476016 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0475629 |
| OGA | O-GlcNAcase | 0.0458493 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0443747 |
| SULF2 | sulfatase 2 | 0.0425239 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.0416361 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0411583 |
| TUFT1 | tuftelin 1 | 0.0406407 |
| DNM2 | dynamin 2 | 0.0405542 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0395483 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0394032 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0389216 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0385326 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0382088 |
| MEF2A | myocyte enhancer factor 2A | 0.0381861 |
| STC2 | stanniocalcin 2 | 0.0381337 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0379795 |
| RUNX1 | runt-related transcription factor 1 | 0.0371544 |
| SEPTIN9 | septin 9 | 0.0364194 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0364154 |
| RNF213 | ring finger protein 213 | 0.0363947 |
| RAD51B | RAD51 paralog B | 0.0363677 |
| HKDC1 | hexokinase domain containing 1 | 0.0356602 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0355255 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0353521 |
| SDC4 | syndecan 4 | 0.0351828 |
| SBF2 | SET binding factor 2 | 0.0349975 |
| PARVA | parvin, alpha | 0.0348442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0346074 |
| RIGI | RNA sensor RIG-I | 0.0344197 |
| INTS6 | integrator complex subunit 6 | 0.0343271 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0337834 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0330717 |
| NEO1 | neogenin 1 | 0.0327346 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0326593 |
| UPP1 | uridine phosphorylase 1 | 0.0323045 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0322913 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.032043 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0316864 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0316782 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0311771 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.0305479 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.030454 |
| FHIT | fragile histidine triad | 0.0300995 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0298662 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0296421 |
| PLSCR1 | phospholipid scramblase 1 | 0.0295744 |
| TPD52L1 | tumor protein D52-like 1 | 0.0293924 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0292093 |
| SP100 | SP100 nuclear antigen | 0.0291545 |
| CAPN5 | calpain 5 | 0.0289325 |
| PTK2 | protein tyrosine kinase 2 | 0.0286172 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0282313 |
| ADM | adrenomedullin | 0.0281858 |
| NABP1 | nucleic acid binding protein 1 | 0.0281464 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0281218 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0277087 |
| MYO1E | myosin IE | 0.0274283 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0273664 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0273082 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0272561 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0272168 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270426 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0268306 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0268261 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0267783 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0265855 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0265835 |
| USP53 | ubiquitin specific peptidase 53 | 0.0265423 |
| DENND4C | DENN/MADD domain containing 4C | 0.0261026 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0260372 |
| RND3 | Rho family GTPase 3 | 0.026 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0258083 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0257881 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) | 0.0256119 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0255999 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0255524 |
| CDK13 | cyclin-dependent kinase 13 | 0.0254577 |
| MX2 | MX dynamin-like GTPase 2 | 0.0253492 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0252278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.15375 |
| FTL | ferritin, light polypeptide | -0.139315 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.131285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0846239 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0837901 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0834337 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.07133 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0671975 |
| PERP | PERP, TP53 apoptosis effector | -0.0670601 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0620809 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0610313 |
| KRT18 | keratin 18, type I | -0.0558123 |
| TMEM123 | transmembrane protein 123 | -0.0542182 |
| TMSB10 | thymosin beta 10 | -0.0494728 |
| KRT8 | keratin 8, type II | -0.0491423 |
| SNX9 | sorting nexin 9 | -0.0471569 |
| MKI67 | marker of proliferation Ki-67 | -0.046447 |
| CCND1 | cyclin D1 | -0.0455975 |
| ZNRF3 | zinc and ring finger 3 | -0.0454597 |
| EPCAM | epithelial cell adhesion molecule | -0.0439778 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0433794 |
| ZNF292 | zinc finger protein 292 | -0.0424015 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0419759 |
| TPX2 | TPX2, microtubule-associated | -0.0417788 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0405144 |
| GNAS | GNAS complex locus | -0.0403241 |
| MATR3 | matrin 3 | -0.0397616 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0396953 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0385292 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0375446 |
| S100A6 | S100 calcium binding protein A6 | -0.0374323 |
| MED13L | mediator complex subunit 13-like | -0.0369483 |
| USP3 | ubiquitin specific peptidase 3 | -0.0361009 |
| H1-0 | H1.0 linker histone | -0.0360171 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0357651 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0344742 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0344173 |
| RPL12 | ribosomal protein L12 | -0.0343846 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.033353 |
| SEPTIN7 | septin 7 | -0.0318885 |
| AHNAK | AHNAK nucleoprotein | -0.0317958 |
| RPS6 | ribosomal protein S6 | -0.0315849 |
| FAT1 | FAT atypical cadherin 1 | -0.031421 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0312351 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0306358 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0306106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302133 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0300592 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0299152 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0298069 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291473 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0289928 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0289883 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287755 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0285763 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0284987 |
| UBC | ubiquitin C | -0.0284965 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0283592 |
| RPL23 | ribosomal protein L23 | -0.0283332 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0280531 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0280188 |
| RPLP0 | ribosomal protein, large, P0 | -0.0278405 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0278091 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0276896 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0272983 |
| IER3 | immediate early response 3 | -0.0269245 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.026713 |
| RBM27 | RNA binding motif protein 27 | -0.0265738 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0265284 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0262258 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0259143 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0259055 |
| CST3 | cystatin C | -0.0258539 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0257559 |
| KIF5B | kinesin family member 5B | -0.025626 |
| COG5 | component of oligomeric golgi complex 5 | -0.0255999 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0254652 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0253274 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.025173 |
| POTEF | POTE ankyrin domain family, member F | -0.024758 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0243394 |
| OLA1 | Obg-like ATPase 1 | -0.0241103 |
| RPL19 | ribosomal protein L19 | -0.0240496 |
| FNBP1L | formin binding protein 1-like | -0.024016 |
| RNF145 | ring finger protein 145 | -0.0239663 |
| RPS5 | ribosomal protein S5 | -0.023925 |
| RPL32 | ribosomal protein L32 | -0.0234996 |
| TMSB4X | thymosin beta 4, X-linked | -0.0233208 |
| MSI2 | musashi RNA-binding protein 2 | -0.0231893 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.023155 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0230724 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0228305 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0228161 |
| CDCP1 | CUB domain containing protein 1 | -0.0227301 |
| DEK | DEK proto-oncogene | -0.0225146 |
| CBX3 | chromobox homolog 3 | -0.0223862 |
| ACTG1 | actin gamma 1 | -0.0222362 |
| S100A10 | S100 calcium binding protein A10 | -0.0222126 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0221581 |
| ZNF207 | zinc finger protein 207 | -0.0216646 |
