| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0470621 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0468688 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.041489 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0377896 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0327961 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0276277 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0275695 |
| UPP1 | uridine phosphorylase 1 | 0.0275535 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0259717 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0254149 |
| SQSTM1 | sequestosome 1 | 0.0243128 |
| RYBP | RING1 and YY1 binding protein | 0.023326 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0227953 |
| SDC4 | syndecan 4 | 0.0224325 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0221673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0213424 |
| MYO5B | myosin VB | 0.0200011 |
| GPC5 | glypican 5 | 0.0199533 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0196703 |
| MYO1B | myosin IB | 0.0184675 |
| XPO1 | exportin 1 | 0.018261 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0176228 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0172192 |
| EFNA5 | ephrin-A5 | 0.0171893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0171797 |
| EZR | ezrin | 0.0157128 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.015042 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0149795 |
| TPD52L1 | tumor protein D52-like 1 | 0.0149201 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0147681 |
| NUP50 | nucleoporin 50kDa | 0.0146874 |
| CD47 | CD47 molecule | 0.0146721 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0143994 |
| EPHA2 | EPH receptor A2 | 0.0143935 |
| YOD1 | YOD1 deubiquitinase | 0.013968 |
| TUFT1 | tuftelin 1 | 0.0138518 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.0131072 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0129946 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0129349 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0128676 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0128442 |
| CCNG2 | cyclin G2 | 0.0127801 |
| MACROD2 | MACRO domain containing 2 | 0.0127434 |
| DMXL1 | Dmx-like 1 | 0.0126167 |
| PDE10A | phosphodiesterase 10A | 0.0125633 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0125055 |
| VEGFA | vascular endothelial growth factor A | 0.0123956 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0120563 |
| KIAA1671 | KIAA1671 | 0.012022 |
| RASAL2 | RAS protein activator like 2 | 0.0120167 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0119955 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.01189 |
| MNT | MAX network transcriptional repressor | 0.0118683 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.011832 |
| SLC43A2 | solute carrier family 43 (amino acid system L transporter), member 2 | 0.0116802 |
| H1-10 | H1.10 linker histone | 0.0116095 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0115906 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0115292 |
| FOSL1 | FOS-like antigen 1 | 0.0114919 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0114396 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0114385 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0112047 |
| DOCK6 | dedicator of cytokinesis 6 | 0.011131 |
| MYO10 | myosin X | 0.0110748 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0110748 |
| INTS6 | integrator complex subunit 6 | 0.0110128 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0109584 |
| IGF2 | insulin-like growth factor 2 | 0.0108708 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0107088 |
| ATN1 | atrophin 1 | 0.0106309 |
| PREPL | prolyl endopeptidase-like | 0.0106294 |
| EPHB2 | EPH receptor B2 | 0.0105849 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.010568 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0105673 |
| INSIG1 | insulin induced gene 1 | 0.0105666 |
| ATF3 | activating transcription factor 3 | 0.0105329 |
| DGKH | diacylglycerol kinase, eta | 0.0104791 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0103333 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 0.0102618 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0101999 |
| SIRT1 | sirtuin 1 | 0.0101855 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 | 0.0101505 |
| LYST | lysosomal trafficking regulator | 0.0100933 |
| ARRDC4 | arrestin domain containing 4 | 0.00997702 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.00994335 |
| TLE4 | transducin-like enhancer of split 4 | 0.00991841 |
| FN1 | fibronectin 1 | 0.00991536 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00988764 |
| ANO10 | anoctamin 10 | 0.00988723 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00987861 |
| NXN | nucleoredoxin | 0.00985359 |
| MEF2D | myocyte enhancer factor 2D | 0.00979633 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00978133 |
| DIPK2A | divergent protein kinase domain 2A | 0.00972792 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00971564 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.00970562 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00965135 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00951396 |
| ADM | adrenomedullin | 0.00949382 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00948064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.229276 |
| EGFR | epidermal growth factor receptor | -0.174366 |
| LMO7 | LIM domain 7 | -0.136864 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.114878 |
| RPS6 | ribosomal protein S6 | -0.113362 |
| OXR1 | oxidation resistance 1 | -0.0859202 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0854083 |
| TMSB10 | thymosin beta 10 | -0.0822623 |
| GOLGA4 | golgin A4 | -0.0749401 |
| RAB10 | RAB10, member RAS oncogene family | -0.0717647 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0702242 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0693732 |
| RPL11 | ribosomal protein L11 | -0.0681013 |
| AREG | amphiregulin | -0.0654339 |
| RPS24 | ribosomal protein S24 | -0.0645622 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0640599 |
| RAD51B | RAD51 paralog B | -0.0639895 |
| RPL23 | ribosomal protein L23 | -0.0638176 |
| RPL26 | ribosomal protein L26 | -0.0625103 |
| RBM25 | RNA binding motif protein 25 | -0.0620938 |
| HDAC2 | histone deacetylase 2 | -0.0616584 |
| TOP1 | topoisomerase (DNA) I | -0.0609693 |
| RPLP1 | ribosomal protein, large, P1 | -0.059763 |
| RPS19 | ribosomal protein S19 | -0.0583187 |
| LAMB3 | laminin, beta 3 | -0.0582919 |
| ATXN1 | ataxin 1 | -0.0579859 |
| RCOR1 | REST corepressor 1 | -0.0555825 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0555142 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0543222 |
| RPL12 | ribosomal protein L12 | -0.0541391 |
| EGR1 | early growth response 1 | -0.0532657 |
| MTAP | methylthioadenosine phosphorylase | -0.0523245 |
| RPS3 | ribosomal protein S3 | -0.0515447 |
| DSPP | dentin sialophosphoprotein | -0.0507005 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0496882 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0494364 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0484892 |
| RPS4X | ribosomal protein S4, X-linked | -0.0476148 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0473435 |
| RPL5 | ribosomal protein L5 | -0.0472959 |
| RPL34 | ribosomal protein L34 | -0.0472565 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0458201 |
| RPLP0 | ribosomal protein, large, P0 | -0.0455908 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0453345 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0452536 |
| RPS8 | ribosomal protein S8 | -0.0447854 |
| SCFD1 | sec1 family domain containing 1 | -0.0447173 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0437446 |
| RPL35A | ribosomal protein L35a | -0.0436909 |
| SERINC5 | serine incorporator 5 | -0.0436552 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0430075 |
| YAP1 | Yes-associated protein 1 | -0.0424725 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0424094 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0421565 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0417833 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.041704 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0414513 |
| RPL18 | ribosomal protein L18 | -0.0407795 |
| NEMF | nuclear export mediator factor | -0.0406446 |
| RPL32 | ribosomal protein L32 | -0.040189 |
| RPL9 | ribosomal protein L9 | -0.0394894 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0392966 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0385671 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0381328 |
| USP34 | ubiquitin specific peptidase 34 | -0.0377858 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0377567 |
| RPLP2 | ribosomal protein, large, P2 | -0.0365717 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0356538 |
| SPATA13 | spermatogenesis associated 13 | -0.0355314 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0353474 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0349633 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0349382 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0348151 |
| EHBP1 | EH domain binding protein 1 | -0.0348096 |
| JMJD1C | jumonji domain containing 1C | -0.034741 |
| RPS13 | ribosomal protein S13 | -0.0347324 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0345577 |
| PHF14 | PHD finger protein 14 | -0.0342415 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0341327 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0341199 |
| CLTC | clathrin, heavy chain (Hc) | -0.0339851 |
| RUNX2 | runt-related transcription factor 2 | -0.0338637 |
| LAMA4 | laminin, alpha 4 | -0.0337869 |
| KIF5B | kinesin family member 5B | -0.0337013 |
| HMGA2 | high mobility group AT-hook 2 | -0.0337003 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0336583 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0329385 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0325719 |
| FAM3C | family with sequence similarity 3, member C | -0.0323851 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0323722 |
| RPL36A | ribosomal protein L36a | -0.032296 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0322506 |
| FLOT1 | flotillin 1 | -0.0322074 |
| CUX1 | cut-like homeobox 1 | -0.0321849 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0321559 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0320794 |
| ZNRF3 | zinc and ring finger 3 | -0.0320667 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0320443 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0318707 |
| SMAD3 | SMAD family member 3 | -0.0318047 |
