| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Selinexor _SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.11957 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0680527 |
| AHNAK | AHNAK nucleoprotein | 0.0558019 |
| INTS6 | integrator complex subunit 6 | 0.0444531 |
| XPO1 | exportin 1 | 0.0395093 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0375381 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0371602 |
| PTMA | prothymosin, alpha | 0.0345534 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0343451 |
| PLEC | plectin | 0.0318599 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0311324 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0274858 |
| CD44 | CD44 molecule (Indian blood group) | 0.0241539 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239828 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0233806 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0220989 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0212491 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.021225 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0196806 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0191668 |
| GLI3 | GLI family zinc finger 3 | 0.0184838 |
| CCND1 | cyclin D1 | 0.0173876 |
| IGF2 | insulin-like growth factor 2 | 0.017352 |
| ARRDC3 | arrestin domain containing 3 | 0.0169519 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0168886 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0168682 |
| CLSTN2 | calsyntenin 2 | 0.0167448 |
| SDC4 | syndecan 4 | 0.0162593 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0161133 |
| PABIR2 | PABIR family member 2 | 0.0158015 |
| EGFR | epidermal growth factor receptor | 0.015801 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.015711 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0157013 |
| EMP1 | epithelial membrane protein 1 | 0.0156705 |
| CADM1 | cell adhesion molecule 1 | 0.0156698 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0154893 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.015263 |
| FHIT | fragile histidine triad | 0.0148386 |
| MCL1 | myeloid cell leukemia 1 | 0.014572 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0144159 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0142792 |
| RBP1 | retinol binding protein 1, cellular | 0.0142718 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0142425 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0140335 |
| NGFR | nerve growth factor receptor | 0.0139403 |
| CAVIN1 | caveolae associated protein 1 | 0.0138963 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0138503 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0136483 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0136436 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0135191 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0133892 |
| APP | amyloid beta (A4) precursor protein | 0.0131711 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0129931 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0128714 |
| TUFT1 | tuftelin 1 | 0.0121083 |
| FLNA | filamin A, alpha | 0.0117362 |
| TRIM2 | tripartite motif containing 2 | 0.0113929 |
| TLE4 | transducin-like enhancer of split 4 | 0.0110804 |
| FTL | ferritin, light polypeptide | 0.0109404 |
| SERINC5 | serine incorporator 5 | 0.0106133 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0105815 |
| FAM107B | family with sequence similarity 107, member B | 0.0105346 |
| LMNA | lamin A/C | 0.0103466 |
| UBAP2 | ubiquitin associated protein 2 | 0.0102969 |
| RCC1 | regulator of chromosome condensation 1 | 0.0102881 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0102577 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.0102313 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.01023 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0101562 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0101369 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.010131 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00999121 |
| KLHL29 | kelch-like family member 29 | 0.00989875 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.00989686 |
| HOXB3 | homeobox B3 | 0.00981495 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00978877 |
| KRT23 | keratin 23, type I | 0.00977528 |
| CCNG2 | cyclin G2 | 0.00976653 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.00968205 |
| TFRC | transferrin receptor | 0.00955392 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0092227 |
| ZNF704 | zinc finger protein 704 | 0.00917107 |
| NABP1 | nucleic acid binding protein 1 | 0.00915876 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00910664 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00907762 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00897625 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.00893793 |
| FUS | FUS RNA binding protein | 0.00892581 |
| FAM169A | family with sequence similarity 169, member A | 0.00890159 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.00880367 |
| LRRC23 | leucine rich repeat containing 23 | 0.00880068 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.00876794 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00875879 |
| BRD2 | bromodomain containing 2 | 0.0087066 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.00865687 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00859617 |
| EDA | ectodysplasin A | 0.0085332 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00851735 |
| MYO10 | myosin X | 0.00850707 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.00844577 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.274737 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.125993 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113512 |
| SYT1 | synaptotagmin I | -0.0950442 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0819165 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0812065 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0763551 |
| NAV2 | neuron navigator 2 | -0.0743961 |
| RUNX1 | runt-related transcription factor 1 | -0.0680719 |
| TNS3 | tensin 3 | -0.0671503 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0649798 |
| RPS6 | ribosomal protein S6 | -0.0625223 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0600636 |
| PROX1 | prospero homeobox 1 | -0.0571797 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0566439 |
| THOC2 | THO complex 2 | -0.0565199 |
| OXR1 | oxidation resistance 1 | -0.0555203 |
| LMO7 | LIM domain 7 | -0.0532314 |
| ATXN1 | ataxin 1 | -0.0512628 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0509519 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0493643 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0491552 |
| ETNK1 | ethanolamine kinase 1 | -0.0480134 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0479612 |
| DST | dystonin | -0.0472217 |
| TMSB10 | thymosin beta 10 | -0.0461935 |
| TMEM123 | transmembrane protein 123 | -0.0457215 |
| PGK1 | phosphoglycerate kinase 1 | -0.0451768 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0447117 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0437261 |
| SBF2 | SET binding factor 2 | -0.0434749 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0432248 |
| RBM25 | RNA binding motif protein 25 | -0.0431037 |
| YAP1 | Yes-associated protein 1 | -0.0422367 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0412549 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0412157 |
| JMJD1C | jumonji domain containing 1C | -0.0409117 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0405975 |
| GLG1 | golgi glycoprotein 1 | -0.0401393 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0400314 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0399401 |
| CD46 | CD46 molecule, complement regulatory protein | -0.039751 |
| NF1 | neurofibromin 1 | -0.0397359 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0394135 |
| VCL | vinculin | -0.0393853 |
| SETD5 | SET domain containing 5 | -0.0392715 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0390826 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0388358 |
| MED13 | mediator complex subunit 13 | -0.0385479 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0382815 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0382523 |
| RBM26 | RNA binding motif protein 26 | -0.0375088 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0375058 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0373577 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0371793 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0363972 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0362673 |
| GOLGA4 | golgin A4 | -0.036067 |
| USP34 | ubiquitin specific peptidase 34 | -0.0360245 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0358108 |
| NKTR | natural killer cell triggering receptor | -0.0356285 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0350705 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0348711 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0345644 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0338542 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0336568 |
| ABHD2 | abhydrolase domain containing 2 | -0.0335448 |
| EGR1 | early growth response 1 | -0.0331609 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0328309 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.032819 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0327672 |
| MORF4L2 | mortality factor 4 like 2 | -0.0327157 |
| BPTF | bromodomain PHD finger transcription factor | -0.0322681 |
| ZNF292 | zinc finger protein 292 | -0.0320721 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0318875 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0314535 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0313142 |
| PERP | PERP, TP53 apoptosis effector | -0.0312637 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0312429 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0312343 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0312227 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0310881 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0308296 |
| RPS12 | ribosomal protein S12 | -0.0306756 |
| RBM39 | RNA binding motif protein 39 | -0.0306681 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.030538 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0303424 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0302044 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0301137 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0300343 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0298976 |
| FOXP1 | forkhead box P1 | -0.0296159 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0296046 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295855 |
| TMEM163 | transmembrane protein 163 | -0.0295412 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0293906 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.029225 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0291985 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0291755 |
| CDH13 | cadherin 13 | -0.0291611 |
