| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Selinexor perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Selinexor _hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.252013 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.121832 |
| VIM | vimentin | 0.0871002 |
| RNF150 | ring finger protein 150 | 0.0681717 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0621251 |
| HMGA2 | high mobility group AT-hook 2 | 0.0618731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.05912 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0514948 |
| FMNL2 | formin-like 2 | 0.0490116 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0470115 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.046523 |
| XPO1 | exportin 1 | 0.0451263 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0448411 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0421344 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0368547 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0363401 |
| RND3 | Rho family GTPase 3 | 0.0336258 |
| VMP1 | vacuole membrane protein 1 | 0.0330606 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0316152 |
| COL5A2 | collagen, type V, alpha 2 | 0.0310961 |
| MEF2A | myocyte enhancer factor 2A | 0.0308473 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0303282 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0295052 |
| FRMD6 | FERM domain containing 6 | 0.0286267 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0275515 |
| MMP12 | matrix metallopeptidase 12 | 0.0269835 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0265653 |
| SDC4 | syndecan 4 | 0.0264331 |
| DNER | delta/notch-like EGF repeat containing | 0.0262498 |
| RYBP | RING1 and YY1 binding protein | 0.0261748 |
| IGF2 | insulin-like growth factor 2 | 0.0255739 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0254161 |
| OGA | O-GlcNAcase | 0.025317 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0247257 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0243063 |
| DENND4C | DENN/MADD domain containing 4C | 0.0234946 |
| FAM13A | family with sequence similarity 13, member A | 0.0221024 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0219856 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0215143 |
| RASA2 | RAS p21 protein activator 2 | 0.0214515 |
| CCNG2 | cyclin G2 | 0.0213903 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0213893 |
| LOX | lysyl oxidase | 0.0212739 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0212008 |
| ACVR1 | activin A receptor, type I | 0.02085 |
| ARRDC3 | arrestin domain containing 3 | 0.0205527 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.02046 |
| SNX9 | sorting nexin 9 | 0.0203021 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.020058 |
| JUN | jun proto-oncogene | 0.0200178 |
| PCDH9 | protocadherin 9 | 0.019836 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0190513 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0185112 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0184965 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0182955 |
| GPHN | gephyrin | 0.0182886 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0182204 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181194 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0178644 |
| NGFR | nerve growth factor receptor | 0.0176398 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0170952 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0170865 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0170471 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0162896 |
| AHNAK | AHNAK nucleoprotein | 0.016275 |
| TMEM200A | transmembrane protein 200A | 0.0161832 |
| GK | glycerol kinase | 0.0159388 |
| USP53 | ubiquitin specific peptidase 53 | 0.0156171 |
| FOXO3 | forkhead box O3 | 0.0155794 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0154749 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0152798 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.0152784 |
| DUSP10 | dual specificity phosphatase 10 | 0.014951 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0147504 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0146736 |
| ACVR1C | activin A receptor, type IC | 0.0145128 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.014431 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0144184 |
| EGR1 | early growth response 1 | 0.0143271 |
| MCL1 | myeloid cell leukemia 1 | 0.0143231 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0142294 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0141799 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0141378 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0141214 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0140005 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0139486 |
| DOCK6 | dedicator of cytokinesis 6 | 0.0138977 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0138245 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0137808 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0137464 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0135013 |
| FOSL1 | FOS-like antigen 1 | 0.0133988 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0133837 |
| FAT1 | FAT atypical cadherin 1 | 0.0133169 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0132315 |
| GPR176 | G protein-coupled receptor 176 | 0.0132213 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0132013 |
| FAM162A | family with sequence similarity 162, member A | 0.0131592 |
| ANO10 | anoctamin 10 | 0.0130756 |
| EMP1 | epithelial membrane protein 1 | 0.0130474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | -0.189663 |
| COL1A1 | collagen, type I, alpha 1 | -0.120495 |
| COL6A3 | collagen, type VI, alpha 3 | -0.104252 |
| OXR1 | oxidation resistance 1 | -0.101704 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0992046 |
| HLA-B | major histocompatibility complex, class I, B | -0.0940605 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0927909 |
| ASPH | aspartate beta-hydroxylase | -0.082439 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0780146 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0760676 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0708137 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0690914 |
| TMSB10 | thymosin beta 10 | -0.0662116 |
| RPS6 | ribosomal protein S6 | -0.0661277 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0642857 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0633655 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0616941 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0593706 |
| COL1A2 | collagen, type I, alpha 2 | -0.0555859 |
| PRSS23 | protease, serine, 23 | -0.0510157 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0508367 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0507165 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0492645 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0472048 |
| MYO10 | myosin X | -0.045666 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0440505 |
| EGFR | epidermal growth factor receptor | -0.0427808 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0422543 |
| FRMD4A | FERM domain containing 4A | -0.0422134 |
| RPL23 | ribosomal protein L23 | -0.0415251 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0412361 |
| ACTG1 | actin gamma 1 | -0.0409388 |
| STC1 | stanniocalcin 1 | -0.0406541 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0384132 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0383326 |
| VCL | vinculin | -0.0382449 |
| COL5A3 | collagen, type V, alpha 3 | -0.0382345 |
| POTEF | POTE ankyrin domain family, member F | -0.0381605 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0381246 |
| RPL26 | ribosomal protein L26 | -0.0378429 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0370567 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.036997 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0368897 |
| CLTC | clathrin, heavy chain (Hc) | -0.0368146 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0366857 |
| LOXL2 | lysyl oxidase-like 2 | -0.0362338 |
| MED13L | mediator complex subunit 13-like | -0.0360208 |
| RPS19 | ribosomal protein S19 | -0.0349412 |
| FBN1 | fibrillin 1 | -0.0347359 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0346209 |
| CALD1 | caldesmon 1 | -0.0340972 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0337499 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0333222 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0330661 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0329595 |
| RPL37A | ribosomal protein L37a | -0.0325414 |
| GOLGB1 | golgin B1 | -0.0322822 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0314717 |
| CD44 | CD44 molecule (Indian blood group) | -0.031451 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0312184 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0311014 |
| RPL34 | ribosomal protein L34 | -0.0310575 |
| RPL11 | ribosomal protein L11 | -0.0310564 |
| GOLGA4 | golgin A4 | -0.0308627 |
| G0S2 | G0/G1 switch 2 | -0.0303109 |
| SEC24D | SEC24 family member D | -0.0300114 |
| RPL35A | ribosomal protein L35a | -0.0299546 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0298 |
| TMF1 | TATA element modulatory factor 1 | -0.0297262 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0296877 |
| NBAS | neuroblastoma amplified sequence | -0.029534 |
| RPL9 | ribosomal protein L9 | -0.0290817 |
| SMAD3 | SMAD family member 3 | -0.0290636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0289253 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0286024 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0284535 |
| ITGA11 | integrin, alpha 11 | -0.0278192 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0277725 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0275068 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0275036 |
| RTN4 | reticulon 4 | -0.0273822 |
| NUMB | numb homolog (Drosophila) | -0.0271571 |
| MYO9A | myosin IXA | -0.0269115 |
| RAI14 | retinoic acid induced 14 | -0.0268936 |
| TMEM165 | transmembrane protein 165 | -0.0267628 |
| B2M | beta-2-microglobulin | -0.0266708 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0265315 |
| PDE8A | phosphodiesterase 8A | -0.0263699 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0262648 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0261998 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0259499 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0259371 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0257338 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0252795 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.025188 |
| RPS13 | ribosomal protein S13 | -0.0250216 |
| RUNX1 | runt-related transcription factor 1 | -0.0247806 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247671 |
| ZNF292 | zinc finger protein 292 | -0.0246388 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0245716 |
