Sepsis_Splenocyte_GSE4479 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4479
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Genes

600 genes differentially expressed during Sepsis_Splenocyte_GSE4479 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
SLC4A3 solute carrier family 4 (anion exchanger), member 3 3.58043
DFNB31 deafness, autosomal recessive 31 3.53503
NME2 NME/NM23 nucleoside diphosphate kinase 2 3.49456
TROAP trophinin associated protein 3.48828
CDH22 cadherin 22, type 2 3.27636
PNPLA2 patatin-like phospholipase domain containing 2 3.27435
UBOX5 U-box domain containing 5 3.16619
GADL1 glutamate decarboxylase-like 1 3.01252
KCP kielin/chordin-like protein 2.84345
ZDHHC3 zinc finger, DHHC-type containing 3 2.82439
RABEPK Rab9 effector protein with kelch motifs 2.82202
FAIM2 Fas apoptotic inhibitory molecule 2 2.78839
IL15RA interleukin 15 receptor, alpha 2.67463
GSTM1 glutathione S-transferase mu 1 2.65821
RPS8 ribosomal protein S8 2.64024
MED26 mediator complex subunit 26 2.6308
TSPAN11 tetraspanin 11 2.59912
VSIG10 V-set and immunoglobulin domain containing 10 2.58255
DOK3 docking protein 3 2.5672
TEX10 testis expressed 10 2.54731
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 2.45012
NEU1 sialidase 1 (lysosomal sialidase) 2.43126
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.42125
COG5 component of oligomeric golgi complex 5 2.39383
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 2.38703
INS insulin 2.36341
KRT78 keratin 78, type II 2.33507
ASB8 ankyrin repeat and SOCS box containing 8 2.32312
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.2941
CASC4 cancer susceptibility candidate 4 2.25828
GBP6 guanylate binding protein family, member 6 2.22502
TTI2 TELO2 interacting protein 2 2.17975
ERF Ets2 repressor factor 2.17858
NINJ1 ninjurin 1 2.16439
PRUNE prune exopolyphosphatase 2.15521
CCIN calicin 2.13811
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 2.11065
GAL3ST1 galactose-3-O-sulfotransferase 1 2.10351
MRPS26 mitochondrial ribosomal protein S26 2.09968
ATRN attractin 2.09092
ADAT3 adenosine deaminase, tRNA-specific 3 2.08598
PBX4 pre-B-cell leukemia homeobox 4 2.08272
NDFIP1 Nedd4 family interacting protein 1 2.07928
LAMA4 laminin, alpha 4 2.07231
ACVR2B activin A receptor, type IIB 2.07113
COL13A1 collagen, type XIII, alpha 1 2.06592
STC2 stanniocalcin 2 2.04151
MEF2B myocyte enhancer factor 2B 2.04089
NFAM1 NFAT activating protein with ITAM motif 1 2.03854
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2.03826
ANO10 anoctamin 10 2.03819
SCN5A sodium channel, voltage gated, type V alpha subunit 2.03544
TPSG1 tryptase gamma 1 2.02999
KLHL11 kelch-like family member 11 2.02885
USP2 ubiquitin specific peptidase 2 2.02547
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.01927
TMEM140 transmembrane protein 140 2.0119
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 2.01111
RPS28 ribosomal protein S28 2.00977
SBSN suprabasin 2.00963
KLHDC2 kelch domain containing 2 1.98092
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.97441
ARSG arylsulfatase G 1.97426
UPK3B uroplakin 3B 1.9702
POGZ pogo transposable element with ZNF domain 1.96938
RGS6 regulator of G-protein signaling 6 1.96841
AKAP7 A kinase (PRKA) anchor protein 7 1.9666
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 1.96501
RPL28 ribosomal protein L28 1.96116
POU2F1 POU class 2 homeobox 1 1.96031
RNMT RNA (guanine-7-) methyltransferase 1.94958
LIPE lipase, hormone-sensitive 1.9261
ISCA2 iron-sulfur cluster assembly 2 1.92063
FOLR2 folate receptor 2 (fetal) 1.91812
HOOK2 hook microtubule-tethering protein 2 1.91508
TTC39A tetratricopeptide repeat domain 39A 1.91323
LAMA2 laminin, alpha 2 1.91117
HIST1H3F histone cluster 1, H3f 1.90374
PTDSS2 phosphatidylserine synthase 2 1.90133
RAD18 RAD18 E3 ubiquitin protein ligase 1.89554
BMP2K BMP2 inducible kinase 1.87537
SOX1 SRY (sex determining region Y)-box 1 1.87261
NPHP1 nephronophthisis 1 (juvenile) 1.86652
PTGES prostaglandin E synthase 1.86301
NMRK1 nicotinamide riboside kinase 1 1.86274
ZNF184 zinc finger protein 184 1.85617
SOWAHB sosondowah ankyrin repeat domain family member B 1.85
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.84618
JDP2 Jun dimerization protein 2 1.83969
RABL3 RAB, member of RAS oncogene family-like 3 1.82985
NRARP NOTCH-regulated ankyrin repeat protein 1.80105
HTRA1 HtrA serine peptidase 1 1.79298
ISX intestine-specific homeobox 1.79106
JUND jun D proto-oncogene 1.78971
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.78825
VMP1 vacuole membrane protein 1 1.77603
ACER1 alkaline ceramidase 1 1.77341
C14ORF2 chromosome 14 open reading frame 2 1.76947
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 1.76776
TIGD3 tigger transposable element derived 3 1.76095
BAG4 BCL2-associated athanogene 4 1.75605
SMYD5 SMYD family member 5 1.75189
NPC1L1 NPC1-like 1 1.74886
USP22 ubiquitin specific peptidase 22 1.74841
MBNL2 muscleblind-like splicing regulator 2 1.74707
PRRC1 proline-rich coiled-coil 1 1.74566
RHOJ ras homolog family member J 1.74381
DAZ2 deleted in azoospermia 2 1.73898
LDHC lactate dehydrogenase C 1.72421
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 1.72122
CA9 carbonic anhydrase IX 1.71999
NMRAL1 NmrA-like family domain containing 1 1.71982
FANCD2 Fanconi anemia, complementation group D2 1.71835
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.71388
SLC35E2B solute carrier family 35, member E2B 1.71275
SYTL3 synaptotagmin-like 3 1.71219
MYO1C myosin IC 1.71207
MYO7A myosin VIIA 1.71018
GATAD2A GATA zinc finger domain containing 2A 1.70338
CYTH3 cytohesin 3 1.69856
CFAP54 cilia and flagella associated 54 1.69185
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 1.69161
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 1.68833
CNPY3 canopy FGF signaling regulator 3 1.68728
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.68498
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 1.67807
AFF1 AF4/FMR2 family, member 1 1.67145
SORBS3 sorbin and SH3 domain containing 3 1.67037
SCAMP5 secretory carrier membrane protein 5 1.66591
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 1.65984
PKP1 plakophilin 1 1.65803
TREX2 three prime repair exonuclease 2 1.65493
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 1.6515
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.65001
PPARA peroxisome proliferator-activated receptor alpha 1.64951
MRPL15 mitochondrial ribosomal protein L15 1.64818
GCLC glutamate-cysteine ligase, catalytic subunit 1.64371
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.64319
RHOU ras homolog family member U 1.64316
LRRC14 leucine rich repeat containing 14 1.64088
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.63939
DACT2 dishevelled-binding antagonist of beta-catenin 2 1.63935
ARHGAP23 Rho GTPase activating protein 23 1.6392
GAA glucosidase, alpha; acid 1.63909
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.63896
TMEM5 transmembrane protein 5 1.63399
SH2D6 SH2 domain containing 6 1.63093
TXNRD3 thioredoxin reductase 3 1.63003
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.62758
KIAA1549 KIAA1549 1.62675
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 1.62367
SYK spleen tyrosine kinase 1.62263
WDR37 WD repeat domain 37 1.62246
ADGRG3 adhesion G protein-coupled receptor G3 1.6199
HKDC1 hexokinase domain containing 1 1.61551
FBXO4 F-box protein 4 1.61532
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.61289
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 1.61284
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.6104
MTMR2 myotubularin related protein 2 1.60937
BRS3 bombesin-like receptor 3 1.60152
COL23A1 collagen, type XXIII, alpha 1 1.60064
NUCB2 nucleobindin 2 1.59916
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.59671
IL12A interleukin 12A 1.59508
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.59303
KRT71 keratin 71, type II 1.59252
SNUPN snurportin 1 1.58699
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.58571
GJD2 gap junction protein, delta 2, 36kDa 1.58417
LIMCH1 LIM and calponin homology domains 1 1.583
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.58033
ZNRF4 zinc and ring finger 4 1.57878
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 1.57772
C6ORF89 chromosome 6 open reading frame 89 1.57456
LRRC19 leucine rich repeat containing 19 1.57392
GMPR guanosine monophosphate reductase 1.56593
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.56141
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.56056
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.55973
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 1.55893
ENHO energy homeostasis associated 1.55749
LBX2 ladybird homeobox 2 1.55714
C11ORF86 chromosome 11 open reading frame 86 1.55479
SPATA25 spermatogenesis associated 25 1.5541
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.5529
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 1.5457
RNF130 ring finger protein 130 1.54477
NSUN7 NOP2/Sun domain family, member 7 1.54281
HAGHL hydroxyacylglutathione hydrolase-like 1.54136
FLYWCH1 FLYWCH-type zinc finger 1 1.54064
BNC2 basonuclin 2 1.53639
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 1.5314
HMGN1 high mobility group nucleosome binding domain 1 1.53058
LTBP1 latent transforming growth factor beta binding protein 1 1.52989
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 1.52656
MDH1 malate dehydrogenase 1, NAD (soluble) 1.52478
KANK3 KN motif and ankyrin repeat domains 3 1.5223
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 1.51157
ARF5 ADP-ribosylation factor 5 1.51151
FRMD5 FERM domain containing 5 1.51028
SPATA24 spermatogenesis associated 24 1.50865
STK24 serine/threonine kinase 24 1.50721
CCDC105 coiled-coil domain containing 105 1.50424
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.50389
AMELY amelogenin, Y-linked 1.50186
MYADML2 myeloid-associated differentiation marker-like 2 1.49811
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 1.49668
SYN1 synapsin I 1.49548
NFIB nuclear factor I/B 1.49284
MNT MAX network transcriptional repressor 1.49176
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator 1.49038
ASXL1 additional sex combs like transcriptional regulator 1 1.49009
SLC22A25 solute carrier family 22, member 25 1.48644
VTCN1 V-set domain containing T cell activation inhibitor 1 1.48089
TTLL10 tubulin tyrosine ligase-like family member 10 1.48059
PEX19 peroxisomal biogenesis factor 19 1.48033
IFT46 intraflagellar transport 46 1.4787
MSR1 macrophage scavenger receptor 1 1.47694
INTS5 integrator complex subunit 5 1.47414
ACOT2 acyl-CoA thioesterase 2 1.46722
ZBTB22 zinc finger and BTB domain containing 22 1.46676
RPS25 ribosomal protein S25 1.46363
ADCY1 adenylate cyclase 1 (brain) 1.46214
SERP2 stress-associated endoplasmic reticulum protein family member 2 1.46212
BEND3 BEN domain containing 3 1.46165
MKRN1 makorin ring finger protein 1 1.46133
C2ORF71 chromosome 2 open reading frame 71 1.45868
MYO1E myosin IE 1.45821
PLCD3 phospholipase C, delta 3 1.45543
NRIP1 nuclear receptor interacting protein 1 1.4549
MIP major intrinsic protein of lens fiber 1.4541
ASPH aspartate beta-hydroxylase 1.45025
CPLX1 complexin 1 1.44925
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.44807
APTX aprataxin 1.44726
THBS3 thrombospondin 3 1.445
DPYSL3 dihydropyrimidinase-like 3 1.4446
CD40 CD40 molecule, TNF receptor superfamily member 5 1.44094
TH tyrosine hydroxylase 1.43649
ROMO1 reactive oxygen species modulator 1 1.43432
SESTD1 SEC14 and spectrin domains 1 1.4337
XKR6 XK, Kell blood group complex subunit-related family, member 6 1.42832
TMEM72 transmembrane protein 72 1.42812
NAIF1 nuclear apoptosis inducing factor 1 1.42803
EPN3 epsin 3 1.42575
PHF20 PHD finger protein 20 1.42301
PARP12 poly (ADP-ribose) polymerase family, member 12 1.42052
VMAC vimentin-type intermediate filament associated coiled-coil protein 1.41825
FGF11 fibroblast growth factor 11 1.41775
NXPH2 neurexophilin 2 1.41505
CPB2 carboxypeptidase B2 (plasma) 1.41452
SUGP1 SURP and G patch domain containing 1 1.41439
OASL 2'-5'-oligoadenylate synthetase-like 1.41427
TDG thymine-DNA glycosylase 1.41181
TRDMT1 tRNA aspartic acid methyltransferase 1 1.41156
TLN2 talin 2 1.41124
TLR5 toll-like receptor 5 1.41098
CH25H cholesterol 25-hydroxylase 1.40899
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 1.40881
TRIM46 tripartite motif containing 46 1.40807
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 1.40775
DUSP1 dual specificity phosphatase 1 1.40773
PMEPA1 prostate transmembrane protein, androgen induced 1 1.40707
ADCY2 adenylate cyclase 2 (brain) 1.39791
CD300A CD300a molecule 1.39671
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1.38935
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 1.3893
MAPK13 mitogen-activated protein kinase 13 1.3885
KDSR 3-ketodihydrosphingosine reductase 1.3883
ETV5 ets variant 5 1.38794
PLCL2 phospholipase C-like 2 1.38562
SHE Src homology 2 domain containing E 1.3848
RPS5 ribosomal protein S5 1.38456
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.38452
TMEM194B transmembrane protein 194B 1.38451
AKR1C3 aldo-keto reductase family 1, member C3 1.38238
TSNAXIP1 translin-associated factor X interacting protein 1 1.38136
TMOD2 tropomodulin 2 (neuronal) 1.37695
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.37685
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.37612
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.37394
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 1.37326
IZUMO4 IZUMO family member 4 1.37215
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.37151
ANGPT4 angiopoietin 4 1.37006
NPY neuropeptide Y 1.36746
BTLA B and T lymphocyte associated 1.36662
TBC1D30 TBC1 domain family, member 30 1.36626
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 1.36458
AMBP alpha-1-microglobulin/bikunin precursor 1.36374
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.35905
MMP7 matrix metallopeptidase 7 1.35734
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 1.3562
GIPC1 GIPC PDZ domain containing family, member 1 1.35514
REM1 RAS (RAD and GEM)-like GTP-binding 1 1.35482
NPAS4 neuronal PAS domain protein 4 1.35373
FAM131C family with sequence similarity 131, member C 1.35291
ZSWIM4 zinc finger, SWIM-type containing 4 1.35124
NMBR neuromedin B receptor 1.34641

decreased expression

Symbol Name Standardized Value
LXN latexin -3.90082
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -3.72737
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -3.19115
ZNF22 zinc finger protein 22 -3.1521
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -3.03097
SLC35A5 solute carrier family 35, member A5 -3.02283
BRPF3 bromodomain and PHD finger containing, 3 -2.9492
RBM20 RNA binding motif protein 20 -2.9309
CLK4 CDC-like kinase 4 -2.91395
CES4A carboxylesterase 4A -2.85182
TOB1 transducer of ERBB2, 1 -2.81439
ORC4 origin recognition complex, subunit 4 -2.80689
C16ORF91 chromosome 16 open reading frame 91 -2.76863
ING1 inhibitor of growth family, member 1 -2.66376
ZBTB37 zinc finger and BTB domain containing 37 -2.63039
GID4 GID complex subunit 4 -2.61489
ZNF790 zinc finger protein 790 -2.59272
UBE4B ubiquitination factor E4B -2.58089
DPYSL2 dihydropyrimidinase-like 2 -2.57298
OSBPL8 oxysterol binding protein-like 8 -2.5324
PRKX protein kinase, X-linked -2.52899
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -2.50379
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -2.49372
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.4905
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.44762
C1ORF52 chromosome 1 open reading frame 52 -2.38682
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.38355
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 -2.3765
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -2.37302
GSTK1 glutathione S-transferase kappa 1 -2.37265
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -2.35227
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.32738
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -2.31692
ITM2B integral membrane protein 2B -2.30722
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.29547
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -2.2884
VPS13B vacuolar protein sorting 13 homolog B (yeast) -2.288
RPA1 replication protein A1, 70kDa -2.25898
C2CD3 C2 calcium-dependent domain containing 3 -2.24786
PANK2 pantothenate kinase 2 -2.23926
ZNF148 zinc finger protein 148 -2.23509
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -2.2008
FAM49B family with sequence similarity 49, member B -2.18602
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -2.16949
FAM8A1 family with sequence similarity 8, member A1 -2.15124
NSUN3 NOP2/Sun domain family, member 3 -2.1494
TBCCD1 TBCC domain containing 1 -2.14665
NUP50 nucleoporin 50kDa -2.14195
PRPF4B pre-mRNA processing factor 4B -2.1241
MAN1A1 mannosidase, alpha, class 1A, member 1 -2.12057
ZNF597 zinc finger protein 597 -2.1164
MED19 mediator complex subunit 19 -2.11083
ABHD13 abhydrolase domain containing 13 -2.10969
ICT1 immature colon carcinoma transcript 1 -2.10394
PDCL3 phosducin-like 3 -2.10167
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -2.1015
TMEM185A transmembrane protein 185A -2.09473
EXOSC1 exosome component 1 -2.08492
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.07148
NKG7 natural killer cell granule protein 7 -2.05817
NABP1 nucleic acid binding protein 1 -2.05689
ARF4 ADP-ribosylation factor 4 -2.05609
C12ORF4 chromosome 12 open reading frame 4 -2.05418
UBE2A ubiquitin-conjugating enzyme E2A -2.04854
IPP intracisternal A particle-promoted polypeptide -2.04196
N4BP2L1 NEDD4 binding protein 2-like 1 -2.03032
ABI1 abl-interactor 1 -2.01127
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.01007
ZC4H2 zinc finger, C4H2 domain containing -2.00812
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.00789
CHID1 chitinase domain containing 1 -1.99675
CAND1 cullin-associated and neddylation-dissociated 1 -1.99142
CCL24 chemokine (C-C motif) ligand 24 -1.98389
SELL selectin L -1.97668
GMPR2 guanosine monophosphate reductase 2 -1.97188
MFSD11 major facilitator superfamily domain containing 11 -1.96581
RAB21 RAB21, member RAS oncogene family -1.93802
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -1.93377
METTL20 methyltransferase like 20 -1.92718
SPATA6 spermatogenesis associated 6 -1.91216
TPD52L2 tumor protein D52-like 2 -1.89944
CYLD cylindromatosis (turban tumor syndrome) -1.89463
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -1.88555
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -1.8749
ZG16 zymogen granule protein 16 -1.86718
CHD9 chromodomain helicase DNA binding protein 9 -1.86712
CBX1 chromobox homolog 1 -1.85636
E2F5 E2F transcription factor 5, p130-binding -1.85425
TES testin LIM domain protein -1.84736
RGS3 regulator of G-protein signaling 3 -1.84594
CEP68 centrosomal protein 68kDa -1.83996
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -1.8376
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -1.83254
CNOT8 CCR4-NOT transcription complex, subunit 8 -1.82987
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) -1.82655
CCR9 chemokine (C-C motif) receptor 9 -1.82097
C12ORF49 chromosome 12 open reading frame 49 -1.81015
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -1.81003
CKLF chemokine-like factor -1.8067
CREBZF CREB/ATF bZIP transcription factor -1.80257
DPY19L3 dpy-19-like 3 (C. elegans) -1.79509
PGRMC2 progesterone receptor membrane component 2 -1.79021
C1ORF21 chromosome 1 open reading frame 21 -1.7851
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.78227
SHROOM1 shroom family member 1 -1.77549
MYNN myoneurin -1.77375
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.77139
PRDM10 PR domain containing 10 -1.77136
MRPS25 mitochondrial ribosomal protein S25 -1.7688
PAIP2B poly(A) binding protein interacting protein 2B -1.76429
FGF13 fibroblast growth factor 13 -1.75468
ZNF706 zinc finger protein 706 -1.75108
ZNF726 zinc finger protein 726 -1.74592
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.72523
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.7167
MRPL33 mitochondrial ribosomal protein L33 -1.71565
SDHAF4 succinate dehydrogenase complex assembly factor 4 -1.70863
GOPC golgi-associated PDZ and coiled-coil motif containing -1.70838
C16ORF45 chromosome 16 open reading frame 45 -1.69785
FBXL8 F-box and leucine-rich repeat protein 8 -1.69618
MSL3 male-specific lethal 3 homolog (Drosophila) -1.69593
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.69233
MOCOS molybdenum cofactor sulfurase -1.69147
RAP2C RAP2C, member of RAS oncogene family -1.6848
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.68296
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -1.68066
MXD4 MAX dimerization protein 4 -1.67995
SETD6 SET domain containing 6 -1.67938
FAM175B family with sequence similarity 175, member B -1.67928
ZBTB1 zinc finger and BTB domain containing 1 -1.67559
ADAT1 adenosine deaminase, tRNA-specific 1 -1.66643
CAPN7 calpain 7 -1.66498
RNF13 ring finger protein 13 -1.66274
FMO5 flavin containing monooxygenase 5 -1.65589
RGS10 regulator of G-protein signaling 10 -1.65298
FNTA farnesyltransferase, CAAX box, alpha -1.64462
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -1.64436
ARMCX3 armadillo repeat containing, X-linked 3 -1.6379
CLIP1 CAP-GLY domain containing linker protein 1 -1.63678
RAB14 RAB14, member RAS oncogene family -1.63041
GGCT gamma-glutamylcyclotransferase -1.62451
PPP1R3E protein phosphatase 1, regulatory subunit 3E -1.62439
ARHGAP12 Rho GTPase activating protein 12 -1.62222
DPY30 dpy-30 homolog (C. elegans) -1.62149
MRPS6 mitochondrial ribosomal protein S6 -1.6209
C6ORF136 chromosome 6 open reading frame 136 -1.62066
RECQL RecQ helicase-like -1.61685
LZIC leucine zipper and CTNNBIP1 domain containing -1.6104
MCTS1 malignant T cell amplified sequence 1 -1.60993
CCNG1 cyclin G1 -1.6062
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -1.59861
UGP2 UDP-glucose pyrophosphorylase 2 -1.59684
SLC7A6OS solute carrier family 7, member 6 opposite strand -1.59676
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -1.59539
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -1.59364
CD200R1 CD200 receptor 1 -1.58957
FBXO18 F-box protein, helicase, 18 -1.58888
MOB3A MOB kinase activator 3A -1.58676
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -1.58628
BCL10 B-cell CLL/lymphoma 10 -1.57908
CHDH choline dehydrogenase -1.57848
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.57175
ZNF236 zinc finger protein 236 -1.56202
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -1.56043
MON2 MON2 homolog (S. cerevisiae) -1.55685
IFT172 intraflagellar transport 172 -1.55046
NRG4 neuregulin 4 -1.54838
AIDA axin interactor, dorsalization associated -1.54824
PRKCB protein kinase C, beta -1.54168
CD3D CD3d molecule, delta (CD3-TCR complex) -1.54127
SIRT5 sirtuin 5 -1.5402
CFDP1 craniofacial development protein 1 -1.53987
CCDC126 coiled-coil domain containing 126 -1.53802
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -1.53408
PRDM15 PR domain containing 15 -1.52913
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.52896
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.52698
MADD MAP-kinase activating death domain -1.52149
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -1.52148
THUMPD3 THUMP domain containing 3 -1.52106
OTUD1 OTU deubiquitinase 1 -1.51849
MOB3B MOB kinase activator 3B -1.51681
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 -1.51628
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.51368
TIGD2 tigger transposable element derived 2 -1.51309
RNF141 ring finger protein 141 -1.51185
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -1.5101
RPL22 ribosomal protein L22 -1.50886
ZMYM2 zinc finger, MYM-type 2 -1.50744
IL4 interleukin 4 -1.50646
TMC6 transmembrane channel-like 6 -1.50284
PHLDA1 pleckstrin homology-like domain, family A, member 1 -1.50243
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) -1.50234
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -1.49998
C15ORF40 chromosome 15 open reading frame 40 -1.49922
WDYHV1 WDYHV motif containing 1 -1.4974
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -1.49724
EFR3A EFR3 homolog A (S. cerevisiae) -1.49047
TTC21B tetratricopeptide repeat domain 21B -1.48783
HECA headcase homolog (Drosophila) -1.48483
LMBRD1 LMBR1 domain containing 1 -1.47657
ATF4 activating transcription factor 4 -1.47593
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -1.47471
MTPAP mitochondrial poly(A) polymerase -1.47437
GLP1R glucagon-like peptide 1 receptor -1.47147
ZNF248 zinc finger protein 248 -1.46922
EPM2AIP1 EPM2A (laforin) interacting protein 1 -1.46904
STAG2 stromal antigen 2 -1.46822
GYG1 glycogenin 1 -1.46743
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase -1.46606
FBXL14 F-box and leucine-rich repeat protein 14 -1.46094
AAK1 AP2 associated kinase 1 -1.45778
RPS24 ribosomal protein S24 -1.45713
TRAT1 T cell receptor associated transmembrane adaptor 1 -1.45533
IFT80 intraflagellar transport 80 -1.45436
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -1.45292
JAZF1 JAZF zinc finger 1 -1.45173
NHLRC3 NHL repeat containing 3 -1.44859
RAB3D RAB3D, member RAS oncogene family -1.44817
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -1.44725
ECH1 enoyl CoA hydratase 1, peroxisomal -1.44666
GABPA GA binding protein transcription factor, alpha subunit 60kDa -1.44651
FAM105A family with sequence similarity 105, member A -1.44647
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -1.44424
STK38L serine/threonine kinase 38 like -1.44013
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -1.43848
RBBP7 retinoblastoma binding protein 7 -1.43798
THAP2 THAP domain containing, apoptosis associated protein 2 -1.43311
GALM galactose mutarotase (aldose 1-epimerase) -1.43276
NGLY1 N-glycanase 1 -1.43249
RAP1B RAP1B, member of RAS oncogene family -1.43109
ZNF250 zinc finger protein 250 -1.4305
IL16 interleukin 16 -1.42962
ADCY7 adenylate cyclase 7 -1.4285
TOB2 transducer of ERBB2, 2 -1.42532
MIER1 mesoderm induction early response 1, transcriptional regulator -1.42455
AGA aspartylglucosaminidase -1.42383
FAM198B family with sequence similarity 198, member B -1.423
SUSD6 sushi domain containing 6 -1.42057
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -1.42053
TUFM Tu translation elongation factor, mitochondrial -1.42046
AMDHD1 amidohydrolase domain containing 1 -1.41951
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -1.41885
METTL3 methyltransferase like 3 -1.41687
GLIPR1 GLI pathogenesis-related 1 -1.41581
TMEM168 transmembrane protein 168 -1.41303
C21ORF91 chromosome 21 open reading frame 91 -1.41303
TADA1 transcriptional adaptor 1 -1.41097
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -1.41097
MSRB2 methionine sulfoxide reductase B2 -1.41061
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -1.41034
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.40831
STK36 serine/threonine kinase 36 -1.40786
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -1.4029
AAGAB alpha- and gamma-adaptin binding protein -1.40267
WDR82 WD repeat domain 82 -1.40048
UBE2F ubiquitin-conjugating enzyme E2F (putative) -1.39902
PARP8 poly (ADP-ribose) polymerase family, member 8 -1.39333
LBR lamin B receptor -1.39273
SIAE sialic acid acetylesterase -1.39266
CD53 CD53 molecule -1.3879
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -1.38612
SEPT6 septin 6 -1.38369
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -1.38193
CD7 CD7 molecule -1.38176
PGM2L1 phosphoglucomutase 2-like 1 -1.38144
PDZD8 PDZ domain containing 8 -1.3811
WRN Werner syndrome, RecQ helicase-like -1.37982
RAP1A RAP1A, member of RAS oncogene family -1.37902
MKKS McKusick-Kaufman syndrome -1.37663
TMPRSS13 transmembrane protease, serine 13 -1.37574
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -1.37437
CCDC47 coiled-coil domain containing 47 -1.3738
TTC9C tetratricopeptide repeat domain 9C -1.37314
C14ORF119 chromosome 14 open reading frame 119 -1.3728
DNAAF2 dynein, axonemal, assembly factor 2 -1.37128
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -1.36825
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -1.36402
PURB purine-rich element binding protein B -1.36027
PCM1 pericentriolar material 1 -1.35733
MON1B MON1 secretory trafficking family member B -1.35578
C16ORF13 chromosome 16 open reading frame 13 -1.35427
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -1.35353
NOL8 nucleolar protein 8 -1.35095
FOXK2 forkhead box K2 -1.34946
S100A10 S100 calcium binding protein A10 -1.34898
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -1.34364
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 -1.34334
SDF2 stromal cell-derived factor 2 -1.3422
PFDN4 prefoldin subunit 4 -1.34168
FASTKD3 FAST kinase domains 3 -1.34121
HOXD13 homeobox D13 -1.33472
TMEM109 transmembrane protein 109 -1.33434
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -1.334
WLS wntless Wnt ligand secretion mediator -1.3294
DHRS7 dehydrogenase/reductase (SDR family) member 7 -1.32813
GM2A GM2 ganglioside activator -1.32747
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -1.3267
DYNLL1 dynein, light chain, LC8-type 1 -1.32296
VAV3 vav 3 guanine nucleotide exchange factor -1.32246