Sertraline Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. (Chemical Entities of Biological Interest Ontology, CHEBI_9123)
External Link http://www.drugbank.ca/drugs/DB01104
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Genes

5 interacting proteins for the Sertraline drug from the curated DrugBank Drug Targets dataset.

Symbol Name
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
MAOA monoamine oxidase A
MAOB monoamine oxidase B
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4